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1FCZ
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ISOTYPE SELECTIVITY OF THE HUMAN RETINOIC ACID NUCLEAR RECEPTOR HRAR: THE COMPLEX WITH THE PANAGONIST RETINOID BMS181156
Descriptor: 4-[3-OXO-3-(5,5,8,8-TETRAMETHYL-5,6,7,8-TETRAHYDRO-NAPHTHALEN-2-YL)-PROPENYL]-BENZOIC ACID, DODECYL-ALPHA-D-MALTOSIDE, RETINOIC ACID RECEPTOR GAMMA-1
Authors:Klaholz, B.P, Mitschler, A, Moras, D, Structural Proteomics in Europe (SPINE)
Deposit date:2000-07-19
Release date:2000-09-11
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.38 Å)
Cite:Structural basis for isotype selectivity of the human retinoic acid nuclear receptor.
J.Mol.Biol., 302, 2000
1HVY
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Human thymidylate synthase complexed with dUMP and Raltitrexed, an antifolate drug, is in the closed conformation
Descriptor: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, BETA-MERCAPTOETHANOL, THYMIDYLATE SYNTHASE, ...
Authors:Phan, J, Koli, S, Minor, W, Dunlap, R.B, Berger, S.H, Lebioda, L.
Deposit date:2001-01-08
Release date:2001-01-31
Last modified:2022-04-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Human thymidylate synthase is in the closed conformation when complexed with dUMP and raltitrexed, an antifolate drug
Biochemistry, 40, 2001
1HM6
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X-RAY STRUCTURE OF FULL-LENGTH ANNEXIN 1
Descriptor: ANNEXIN 1, SULFATE ION
Authors:Rosengarth, A, Gerke, V, Luecke, H.
Deposit date:2000-12-04
Release date:2001-02-28
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:X-ray structure of full-length annexin 1 and implications for membrane aggregation.
J.Mol.Biol., 306, 2001
1GML
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crystal structure of the mouse CCT gamma apical domain (triclinic)
Descriptor: GLYCEROL, T-COMPLEX PROTEIN 1 SUBUNIT GAMMA
Authors:Pappenberger, G, Wilsher, J.A, Roe, S.M, Willison, K.R, Pearl, L.H.
Deposit date:2001-09-17
Release date:2002-06-18
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal Structure of the Cct Gamma Apical Domain:: Implications for Substrate Binding to the Eukaryotic Cytosolic Chaperonin
J.Mol.Biol., 318, 2002
1GN1
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crystal structure of the mouse CCT gamma apical domain (monoclinic)
Descriptor: CALCIUM ION, CCT-GAMMA
Authors:Pappenberger, G, Wilsher, J.A, Roe, S.M, Willison, K.R, Pearl, L.H.
Deposit date:2001-10-01
Release date:2002-06-18
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal Structure of the Cct Gamma Apical Domain:: Implications for Substrate Binding to the Eukaryotic Cytosolic Chaperonin
J.Mol.Biol., 318, 2002
1GK4
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HUMAN VIMENTIN COIL 2B FRAGMENT (CYS2)
Descriptor: ACETATE ION, VIMENTIN
Authors:Strelkov, S.V, Herrmann, H, Geisler, N, Zimbelmann, R, Aebi, U, Burkhard, P.
Deposit date:2001-08-08
Release date:2002-03-15
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Conserved Segments 1A and 2B of the Intermediate Filament Dimer: Their Atomic Structures and Role in Filament Assembly.
Embo J., 21, 2002
1IBR
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COMPLEX OF RAN WITH IMPORTIN BETA
Descriptor: GTP-binding nuclear protein RAN, Importin beta-1 subunit, MAGNESIUM ION, ...
Authors:Vetter, I.R, Arndt, A, Kutay, U, Goerlich, D, Wittinghofer, A.
Deposit date:1999-05-14
Release date:1999-06-03
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural view of the Ran-Importin beta interaction at 2.3 A resolution
Cell(Cambridge,Mass.), 97, 1999
1I10
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HUMAN MUSCLE L-LACTATE DEHYDROGENASE M CHAIN, TERNARY COMPLEX WITH NADH AND OXAMATE
Descriptor: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ACETATE ION, L-LACTATE DEHYDROGENASE M CHAIN, ...
Authors:Read, J.A, Winter, V.J, Eszes, C.M, Sessions, R.B, Brady, R.L.
Deposit date:2001-01-30
Release date:2001-03-28
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for altered activity of M- and H-isozyme forms of human lactate dehydrogenase.
Proteins, 43, 2001
1I2M
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RAN-RCC1-SO4 COMPLEX
Descriptor: GTP-BINDING NUCLEAR PROTEIN RAN, REGULATOR OF CHROMOSOME CONDENSATION 1, SULFATE ION
Authors:Renault, L, Kuhlmann, J, Henkel, A, Wittinghofer, A.
Deposit date:2001-02-11
Release date:2001-05-02
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Structural basis for guanine nucleotide exchange on Ran by the regulator of chromosome condensation (RCC1).
Cell(Cambridge,Mass.), 105, 2001
1HVE
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STRUCTURAL AND ELECTROPHYSIOLOGICAL ANALYSIS OF ANNEXIN V MUTANTS. MUTAGENESIS OF HUMAN ANNEXIN V, AN IN VITRO VOLTAGE-GATED CALCIUM CHANNEL, PROVIDES INFORMATION ABOUT THE STRUCTURAL FEATURES OF THE ION PATHWAY, THE VOLTAGE SENSOR AND THE ION SELECTIVITY FILTER
Descriptor: ANNEXIN V, CALCIUM ION, SULFATE ION
Authors:Burger, A, Huber, R.
Deposit date:1994-06-29
Release date:1995-03-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural and electrophysiological analysis of annexin V mutants. Mutagenesis of human annexin V, an in vitro voltage-gated calcium channel, provides information about the structural features of the ion pathway, the voltage sensor and the ion selectivity filter
J.Mol.Biol., 237, 1994
1HMP
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THE CRYSTAL STRUCTURE OF HUMAN HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE WITH BOUND GMP
Descriptor: GUANOSINE-5'-MONOPHOSPHATE, HYPOXANTHINE GUANINE PHOSPHORIBOSYL-TRANSFERASE
Authors:Eads, J.C, Scapin, G, Xu, Y, Grubmeyer, C, Sacchettini, J.C.
Deposit date:1994-06-03
Release date:1995-06-03
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The crystal structure of human hypoxanthine-guanine phosphoribosyltransferase with bound GMP.
Cell(Cambridge,Mass.), 78, 1994
1HVD
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STRUCTURAL AND ELECTROPHYSIOLOGICAL ANALYSIS OF ANNEXIN V MUTANTS. MUTAGENESIS OF HUMAN ANNEXIN V, AN IN VITRO VOLTAGE-GATED CALCIUM CHANNEL, PROVIDES INFORMATION ABOUT THE STRUCTURAL FEATURES OF THE ION PATHWAY, THE VOLTAGE SENSOR AND THE ION SELECTIVITY FILTER
Descriptor: ANNEXIN V, CALCIUM ION
Authors:Burger, A, Huber, R.
Deposit date:1994-06-29
Release date:1995-03-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural and electrophysiological analysis of annexin V mutants. Mutagenesis of human annexin V, an in vitro voltage-gated calcium channel, provides information about the structural features of the ion pathway, the voltage sensor and the ion selectivity filter
J.Mol.Biol., 237, 1994
1HVF
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STRUCTURAL AND ELECTROPHYSIOLOGICAL ANALYSIS OF ANNEXIN V MUTANTS. MUTAGENESIS OF HUMAN ANNEXIN V, AN IN VITRO VOLTAGE-GATED CALCIUM CHANNEL, PROVIDES INFORMATION ABOUT THE STRUCTURAL FEATURES OF THE ION PATHWAY, THE VOLTAGE SENSOR AND THE ION SELECTIVITY FILTER
Descriptor: ANNEXIN V, CALCIUM ION, SULFATE ION
Authors:Burger, A, Huber, R.
Deposit date:1994-06-29
Release date:1995-03-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural and electrophysiological analysis of annexin V mutants. Mutagenesis of human annexin V, an in vitro voltage-gated calcium channel, provides information about the structural features of the ion pathway, the voltage sensor and the ion selectivity filter
J.Mol.Biol., 237, 1994
1HVG
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STRUCTURAL AND ELECTROPHYSIOLOGICAL ANALYSIS OF ANNEXIN V MUTANTS. MUTAGENESIS OF HUMAN ANNEXIN V, AN IN VITRO VOLTAGE-GATED CALCIUM CHANNEL, PROVIDES INFORMATION ABOUT THE STRUCTURAL FEATURES OF THE ION PATHWAY, THE VOLTAGE SENSOR AND THE ION SELECTIVITY FILTER
Descriptor: ANNEXIN V
Authors:Burger, A, Huber, R.
Deposit date:1994-06-29
Release date:1995-03-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural and electrophysiological analysis of annexin V mutants. Mutagenesis of human annexin V, an in vitro voltage-gated calcium channel, provides information about the structural features of the ion pathway, the voltage sensor and the ion selectivity filter
J.Mol.Biol., 237, 1994
1F68
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NMR SOLUTION STRUCTURE OF THE BROMODOMAIN FROM HUMAN GCN5
Descriptor: HISTONE ACETYLTRANSFERASE
Authors:Wright, P.E, Hudson, B.P, Dyson, H.J.
Deposit date:2000-06-20
Release date:2000-12-13
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution structure and acetyl-lysine binding activity of the GCN5 bromodomain.
J.Mol.Biol., 304, 2000
1F95
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SOLUTION STRUCTURE OF DYNEIN LIGHT CHAIN 8 (DLC8) AND BIM PEPTIDE COMPLEX
Descriptor: BCL2-LIKE 11 (APOPTOSIS FACILITATOR), DYNEIN
Authors:Fan, J.-S, Zhang, Q, Tochio, H, Li, M, Zhang, M.
Deposit date:2000-07-07
Release date:2001-02-28
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Structural basis of diverse sequence-dependent target recognition by the 8 kDa dynein light chain.
J.Mol.Biol., 306, 2001
1FCY
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ISOTYPE SELECTIVITY OF THE HUMAN RETINOIC ACID NUCLEAR RECEPTOR HRAR: THE COMPLEX WITH THE RARBETA/GAMMA-SELECTIVE RETINOID CD564
Descriptor: 6-(5,5,8,8-TETRAMETHYL-5,6,7,8-TETRAHYDRO-NAPHTALENE-2-CARBONYL)-NAPHTALENE-2-CARBOXYLIC ACID, DODECYL-ALPHA-D-MALTOSIDE, RETINOIC ACID RECEPTOR GAMMA-1
Authors:Klaholz, B.P, Mitschler, A, Moras, D, Structural Proteomics in Europe (SPINE)
Deposit date:2000-07-19
Release date:2000-09-11
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Structural basis for isotype selectivity of the human retinoic acid nuclear receptor.
J.Mol.Biol., 302, 2000
1F96
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SOLUTION STRUCTURE OF DYNEIN LIGHT CHAIN 8 (DLC8) AND NNOS PEPTIDE COMPLEX
Descriptor: DYNEIN LIGHT CHAIN 8, PROTEIN (NNOS, NEURONAL NITRIC OXIDE SYNTHASE)
Authors:Fan, J.S, Zhang, Q, Tochio, H, Li, M, Zhang, M.
Deposit date:2000-07-07
Release date:2001-02-28
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Structural basis of diverse sequence-dependent target recognition by the 8 kDa dynein light chain.
J.Mol.Biol., 306, 2001
1J4E
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FRUCTOSE-1,6-BISPHOSPHATE ALDOLASE COVALENTLY BOUND TO THE SUBSTRATE DIHYDROXYACETONE PHOSPHATE
Descriptor: 1,3-DIHYDROXYACETONEPHOSPHATE, FRUCTOSE-BISPHOSPHATE ALDOLASE A
Authors:Choi, K.H, Shi, J, Hopkins, C.E, Tolan, D.R, Allen, K.N.
Deposit date:2001-09-19
Release date:2002-02-13
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Snapshots of catalysis: the structure of fructose-1,6-(bis)phosphate aldolase covalently bound to the substrate dihydroxyacetone phosphate.
Biochemistry, 40, 2001
1GG5
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CRYSTAL STRUCTURE OF A COMPLEX OF HUMAN NAD[P]H-QUINONE OXIDOREDUCTASE AND A CHEMOTHERAPEUTIC DRUG (E09) AT 2.5 A RESOLUTION
Descriptor: 3-HYDROXYMETHYL-5-AZIRIDINYL-1METHYL-2-[1H-INDOLE-4,7-DIONE]-PROPANOL, FLAVIN-ADENINE DINUCLEOTIDE, NAD(P)H DEHYDROGENASE [QUINONE] 1
Authors:Faig, M, Bianchet, M.A, Winski, S, Hargreaves, R, Moody, C.J, Hudnott, A.R, Ross, D, Amzel, L.M.
Deposit date:2000-07-12
Release date:2001-09-12
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure-based development of anticancer drugs: complexes of NAD(P)H:quinone oxidoreductase 1 with chemotherapeutic quinones.
Structure, 9, 2001
1GDF
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STRUCTURE OF RHOGDI: A C-TERMINAL BINDING DOMAIN TARGETS AN N-TERMINAL INHIBITORY PEPTIDE TO GTPASES, NMR, MINIMIZED AVERAGE STRUCTURE
Descriptor: RHOGDI
Authors:Rosen, M.K, Gosser, Y.Q.
Deposit date:1997-05-11
Release date:1997-11-19
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:C-terminal binding domain of Rho GDP-dissociation inhibitor directs N-terminal inhibitory peptide to GTPases.
Nature, 387, 1997
1G5N
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ANNEXIN V COMPLEX WITH HEPARIN OLIGOSACCHARIDES
Descriptor: 4-deoxy-2-O-sulfo-alpha-L-threo-hex-4-enopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, ANNEXIN V, CALCIUM ION
Authors:Capila, I, Heraiz, M.J, Mo, Y.D, Mealy, T.R, Campos, B, Dedman, J.R, Linhardt, R.J, Seaton, B.A.
Deposit date:2000-11-01
Release date:2001-06-06
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Annexin V--heparin oligosaccharide complex suggests heparan sulfate--mediated assembly on cell surfaces.
Structure, 9, 2001
1J0X
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Crystal structure of the rabbit muscle glyceraldehyde-3-phosphate dehydrogenase (GAPDH)
Descriptor: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, glyceraldehyde-3-phosphate dehydrogenase
Authors:Cowan-Jacob, S.W, Kaufmann, M, Anselmo, A.N, Stark, W, Grutter, M.G.
Deposit date:2002-11-25
Release date:2003-12-09
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of rabbit-muscle glyceraldehyde-3-phosphate dehydrogenase.
Acta Crystallogr.,Sect.D, 59, 2003
1IQT
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Solution structure of the C-terminal RNA-binding domain of heterogeneous nuclear ribonucleoprotein D0 (AUF1)
Descriptor: heterogeneous nuclear ribonucleoprotein D0
Authors:Katahira, M, Miyanoiri, Y, Enokizono, Y, Matsuda, G, Nagata, T, Ishikawa, F, Uesugi, S.
Deposit date:2001-08-01
Release date:2002-08-07
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Structure of the C-terminal RNA-binding domain of hnRNP D0 (AUF1), its interactions with RNA and DNA, and change in backbone dynamics upon complex formation with DNA.
J.Mol.Biol., 311, 2001
2YTC
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Solution structure of RNA binding domain in Pre-mRNA-splicing factor RBM22
Descriptor: Pre-mRNA-splicing factor RBM22
Authors:Kasahara, N, Tsuda, K, Muto, Y, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-04-05
Release date:2007-10-09
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure of RNA binding domain in Pre-mRNA-splicing factor RBM22
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