PDB: 17153 resultsInfo pagesStatus searchChemie searchBIRD

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8DOA	Solution structure of a model HEEH mini-protein (HEEH_TK_rd5_0958) Descriptor: HEEH mini-protein TK_rd5_0958 Authors: Houliston, S, Kim, T.-E, Rocklin, G, Arrowsmith, C.H. Deposit date: 2022-07-12 Release date: 2022-10-05 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: Dissecting the stability determinants of a challenging de novo protein fold using massively parallel design and experimentation. Proc.Natl.Acad.Sci.USA, 119, 2022
8EB2	Structure of HLA-A*02:01 in complex with NY-ESO-1 peptide and PA2.1 Fab Descriptor: Beta-2-microglobulin, HLA-A*02:01 alpha chain, NY-ESO-1 peptide, ... Authors: Jette, C.A, West, A.P. Deposit date: 2022-08-30 Release date: 2022-11-30 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.9 Å) Cite: HLA-A∗02-gated safety switch for cancer therapy has exquisite specificity for its allelic target antigen. Mol Ther Oncolytics, 27, 2022
8ELG	Crystal Structure of HLA-B*15:01 in complex with spike derived peptide NQKLIANAF from OC43 virus Descriptor: ACETATE ION, Beta-2-microglobulin, NQK-OC43 peptide, ... Authors: Murdolo, L.D, Gras, S. Deposit date: 2022-09-24 Release date: 2023-06-14 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.65 Å) Cite: A common allele of HLA is associated with asymptomatic SARS-CoV-2 infection. Nature, 620, 2023
8ELH	Crystal Structure of HLA-B*15:01 in complex with spike derived peptide NQKLIANQF from SARS-CoV-2 virus Descriptor: ACETATE ION, Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, ... Authors: Murdolo, L.D, Gras, S. Deposit date: 2022-09-24 Release date: 2023-06-14 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.85 Å) Cite: A common allele of HLA is associated with asymptomatic SARS-CoV-2 infection. Nature, 620, 2023
6WN7	Homo sapiens S100A5 Descriptor: CALCIUM ION, Protein S100-A5 Authors: Perkins, A, Harms, M.J, Wong, C.E, Wheeler, L.C. Deposit date: 2020-04-22 Release date: 2020-09-30 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.25 Å) Cite: Learning peptide recognition rules for a low-specificity protein. Protein Sci., 29, 2020
6MQF	Myotoxin II from Bothrops moojeni complexed with Acetylsalicylic acid Descriptor: 2-(ACETYLOXY)BENZOIC ACID, Basic phospholipase A2 homolog 2, DIMETHYL SULFOXIDE Authors: Salvador, G.H.M, Fontes, M.R.M. Deposit date: 2018-10-09 Release date: 2019-03-20 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.693 Å) Cite: Search for efficient inhibitors of myotoxic activity induced by ophidian phospholipase A2-like proteins using functional, structural and bioinformatics approaches. Sci Rep, 9, 2019
3V4O	Human MALT1 (caspase domain) in complex with an irreversible peptidic inhibitor Descriptor: MALT1 Inhibitor, Mucosa-associated lymphoid tissue lymphoma translocation protein 1 Authors: Renatus, M, Wiesmann, C. Deposit date: 2011-12-15 Release date: 2012-03-14 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Structural Determinants of MALT1 Protease Activity. J.Mol.Biol., 419, 2012
5WLJ	De Novo Design of Polynuclear Transition Metal Clusters in Helix Bundles-4EH1 Descriptor: De Novo Metal Binding Helical Bundle, ZINC ION Authors: Zhang, S.-Q, Liu, L, DeGrado, W.F. Deposit date: 2017-07-27 Release date: 2018-01-03 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.6 Å) Cite: De Novo Design of Tetranuclear Transition Metal Clusters Stabilized by Hydrogen-Bonded Networks in Helical Bundles. J. Am. Chem. Soc., 140, 2018
5WLM	De Novo Design of Polynuclear Transition Metal Clusters in Helix Bundles-4DH2 Descriptor: Helical Bundle 4DH2, ZINC ION Authors: Zhang, S.-Q, Liu, L, DeGrado, W.F. Deposit date: 2017-07-27 Release date: 2018-01-03 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.95 Å) Cite: De Novo Design of Tetranuclear Transition Metal Clusters Stabilized by Hydrogen-Bonded Networks in Helical Bundles. J. Am. Chem. Soc., 140, 2018
5WLK	De Novo Design of Polynuclear Transition Metal Clusters in Helix Bundles-4EH2 Descriptor: Helical Bundle 4EH2, ZINC ION Authors: Zhang, S.-Q, Liu, L, DeGrado, W.F. Deposit date: 2017-07-27 Release date: 2018-01-03 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.8 Å) Cite: De Novo Design of Tetranuclear Transition Metal Clusters Stabilized by Hydrogen-Bonded Networks in Helical Bundles. J. Am. Chem. Soc., 140, 2018
3VK8	Crystal structure of DNA-glycosylase bound to DNA containing Thymine glycol Descriptor: DNA (5'-D(*CP*GP*TP*CP*CP*AP*(CTG)P*GP*TP*CP*TP*AP*C)-3'), DNA (5'-D(*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*G)-3'), GLYCEROL, ... Authors: Imamura, K, Averill, A, Wallace, S.S, Doublie, S. Deposit date: 2011-11-10 Release date: 2011-12-14 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (2 Å) Cite: Structural characterization of viral ortholog of human DNA glycosylase NEIL1 bound to thymine glycol or 5-hydroxyuracil-containing DNA J.Biol.Chem., 287, 2012
3LY2	Catalytic Domain of Human Phosphodiesterase 4B in Complex with A Coumarin-Based Inhibitor Descriptor: 8-(cyclopentyloxy)-4-[(3,5-dichloropyridin-4-yl)amino]-7-methoxy-2H-chromen-2-one, MAGNESIUM ION, SULFATE ION, ... Authors: Shiau, A.K, Coyle, A.R, Hsien, J.H, Staszewski, L.M. Deposit date: 2010-02-26 Release date: 2010-04-28 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Water-soluble PDE4 inhibitors for the treatment of dry eye. Bioorg.Med.Chem.Lett., 20, 2010
3MOE	The structure of rat cytosolic PEPCK mutant A467G in complex with Beta-Sulfopyruvate and GTP Descriptor: 1,2-ETHANEDIOL, GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, ... Authors: Johnson, T.A, Holyoak, T. Deposit date: 2010-04-22 Release date: 2010-06-02 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.25 Å) Cite: Increasing the conformational entropy of the Omega-loop lid domain in phosphoenolpyruvate carboxykinase impairs catalysis and decreases catalytic fidelity . Biochemistry, 49, 2010
1LVN	CRYSTAL STRUCTURE OF E. COLI AMINE OXIDASE COMPLEXED WITH TRANYLCYPROMINE Descriptor: CALCIUM ION, COPPER (II) ION, Copper amine oxidase Authors: Wilmot, C.M, Phillips, S.E. Deposit date: 2002-05-28 Release date: 2003-08-05 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Medical implications from the crystal structure of a copper-containing amine oxidase complexed with the antidepressant drug tranylcypromine. Febs Lett., 576, 2004
1LW9	Multiple methionine substitutions are tolerated in T4 lysozyme and have coupled effects on folding and stability Descriptor: 2-HYDROXYETHYL DISULFIDE, CHLORIDE ION, LYSOZYME, ... Authors: Gassner, N.C, Baase, W.A, Mooers, B.H.M, Busam, R.D, Weaver, L.H, Lindstrom, J.D, Quillin, M.L, Matthews, B.W. Deposit date: 2002-05-30 Release date: 2003-05-20 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (1.45 Å) Cite: Multiple methionine substitutions are tolerated in T4 lysozyme and have coupled effects on folding and stability. Biophys.Chem., 100, 2003
8OLT	Mitochondrial complex I from Mus musculus in the active state bound with piericidin A Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ... Authors: Grba, D.N, Chung, I, Bridges, H.R, Agip, A.N.A, Hirst, J. Deposit date: 2023-03-30 Release date: 2023-08-09 Method: ELECTRON MICROSCOPY (2.84 Å) Cite: Investigation of hydrated channels and proton pathways in a high-resolution cryo-EM structure of mammalian complex I. Sci Adv, 9, 2023
8OM1	Mitochondrial complex I from Mus musculus in the active state Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ... Authors: Grba, D.N, Chung, I, Bridges, H.R, Agip, A.N.A, Hirst, J. Deposit date: 2023-03-31 Release date: 2023-08-09 Last modified: 2023-08-16 Method: ELECTRON MICROSCOPY (2.39 Å) Cite: Investigation of hydrated channels and proton pathways in a high-resolution cryo-EM structure of mammalian complex I. Sci Adv, 9, 2023
6S94	Crystal structure of group D of Usutu virus envelope protein domain III Descriptor: Genome polyprotein Authors: Schoenenwald, A.K.J, Skern, T. Deposit date: 2019-07-11 Release date: 2020-08-26 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.79 Å) Cite: Structural and antigenic investigation of Usutu virus envelope protein domain III. Virology, 551, 2020
6S92	Crystal structure of group A of Usutu virus envelope protein domain III Descriptor: Genome polyprotein Authors: Schoenenwald, A.K.J, Skern, T. Deposit date: 2019-07-11 Release date: 2020-08-26 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.93 Å) Cite: Structural and antigenic investigation of Usutu virus envelope protein domain III. Virology, 551, 2020
6S95	Crystal structure of group I of Usutu virus envelope protein domain III Descriptor: Genome polyprotein Authors: Schoenenwald, A.K.J, Skern, T. Deposit date: 2019-07-11 Release date: 2020-08-26 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.19 Å) Cite: Structural and antigenic investigation of Usutu virus envelope protein domain III. Virology, 551, 2020
6SBT	Structure of GluK1 ligand-binding domain (S1S2) in complex with N-(7-(1H-imidazol-1-yl)-2,3-dioxo-6-(trifluoromethyl)-3,4-dihydroquinoxalin-1(2H)-yl benzamide at 2.3 A resolution Descriptor: CHLORIDE ION, GLYCEROL, Glutamate receptor ionotropic, ... Authors: Moellerud, S, Frydenvang, K, Kastrup, J.S. Deposit date: 2019-07-22 Release date: 2019-10-30 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (2.3 Å) Cite: N-(7-(1H-Imidazol-1-yl)-2,3-dioxo-6-(trifluoromethyl)-3,4-dihydroquinoxalin-1(2H)-yl)benzamide, a New Kainate Receptor Selective Antagonist and Analgesic: Synthesis, X-ray Crystallography, Structure-Affinity Relationships, and in Vitro and in Vivo Pharmacology. Acs Chem Neurosci, 10, 2019
7U6B	Crystal Structure of Danio rerio Histone Deacetylase 10 in Complex with Indolethyl Piperidine-4-acrylhydroxamic Acid Inhibitor Descriptor: (2E)-N-hydroxy-3-{1-[2-(1H-indol-3-yl)ethyl]piperidin-4-yl}prop-2-enamide, PHOSPHATE ION, POTASSIUM ION, ... Authors: Herbst-Gervasoni, C.J, Christianson, D.W. Deposit date: 2022-03-03 Release date: 2022-04-06 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Identification of histone deacetylase 10 (HDAC10) inhibitors that modulate autophagy in transformed cells. Eur.J.Med.Chem., 234, 2022
316D	Selectivity of F8-actinomycin D for RNA:DNA hybrids and its anti-leukemia activity Descriptor: 8-FLUORO-ACTINOMYCIN D, DNA (5'-D(*GP*AP*AP*GP*CP*TP*TP*C)-3') Authors: Takusagawa, F, Takusagawa, K.T, Carlson, R.G, Weaver, R.F. Deposit date: 1997-03-05 Release date: 1997-11-05 Last modified: 2024-07-10 Method: X-RAY DIFFRACTION (3 Å) Cite: Selectivity of F8-Actinomycin D for RNA:DNA Hybrids and its Anti-Leukemia Activity. Bioorg.Med.Chem., 5, 1997
7U69	Crystal Structure of Danio rerio Histone Deacetylase 10 in Complex with Phenethyl Piperidine-4-acrylhydroxamic Acid Inhibitor Descriptor: (2E)-N-hydroxy-3-[1-(2-phenylethyl)piperidin-4-yl]prop-2-enamide, PHOSPHATE ION, POTASSIUM ION, ... Authors: Herbst-Gervasoni, C.J, Christianson, D.W. Deposit date: 2022-03-03 Release date: 2022-04-06 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Identification of histone deacetylase 10 (HDAC10) inhibitors that modulate autophagy in transformed cells. Eur.J.Med.Chem., 234, 2022
7U6A	Crystal Structure of Danio rerio Histone Deacetylase 10 in Complex with 3-thienylmethyl Benzhydroxamic Acid Inhibitor Descriptor: 1,2-ETHANEDIOL, N-hydroxy-4-({[(thiophen-3-yl)methyl]amino}methyl)benzamide, PHOSPHATE ION, ... Authors: Herbst-Gervasoni, C.J, Christianson, D.W. Deposit date: 2022-03-03 Release date: 2022-04-06 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.25 Å) Cite: Identification of histone deacetylase 10 (HDAC10) inhibitors that modulate autophagy in transformed cells. Eur.J.Med.Chem., 234, 2022

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