9ENN
| L-amino acid oxidase 4 (HcLAAO4) from the fungus Hebeloma cylindrosporum in complex with N-epsilon-acetyl-L-lysine | Descriptor: | DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, L-amino acid oxidase 4, N(6)-ACETYLLYSINE, ... | Authors: | Gilzer, D, Koopmeiners, S, Fischer von Mollard, G, Niemann, H.H. | Deposit date: | 2024-03-13 | Release date: | 2024-08-14 | Last modified: | 2024-08-28 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure and enzyme engineering of the broad substrate spectrum l-amino acid oxidase 4 from the fungus Hebeloma cylindrosporum. Febs Lett., 2024
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9G0K
| CysG(N-16) in complex with SAH (metal free, cocrystallization in presence of EDTA) from Kitasatospora cystarginea | Descriptor: | 1,2-ETHANEDIOL, S-ADENOSYL-L-HOMOCYSTEINE, SAM-dependent methyltransferase | Authors: | Kuttenlochner, W, Beller, P, Kaysser, L, Groll, M. | Deposit date: | 2024-07-08 | Release date: | 2024-07-17 | Last modified: | 2024-09-18 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Deciphering the SAM- and metal-dependent mechanism of O-methyltransferases in cystargolide and belactosin biosynthesis: A structure-activity relationship study. J.Biol.Chem., 300, 2024
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7ANZ
| Structure of the Candida albicans gamma-Tubulin Small Complex | Descriptor: | Spindle pole body component, Tubulin gamma chain | Authors: | Zupa, E, Pfeffer, S. | Deposit date: | 2020-10-13 | Release date: | 2020-11-04 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | The cryo-EM structure of a gamma-TuSC elucidates architecture and regulation of minimal microtubule nucleation systems. Nat Commun, 11, 2020
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9AVW
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9FFD
| STRUCTURE OF ALDO-KETO REDUCTASE 1C3 (AKR1C3) IN COMPLEX WITH AN INHIBITOR MEDS765 | Descriptor: | 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Aldo-keto reductase family 1 member C3, ... | Authors: | Frydenvang, K, Hussain, S, Mirza, O.A. | Deposit date: | 2024-05-23 | Release date: | 2024-08-21 | Last modified: | 2024-08-28 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | AI Based Discovery of a New AKR1C3 Inhibitor for Anticancer Applications. Acs Med.Chem.Lett., 15, 2024
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9BVU
| NMR structure of TLP-2 in solution | Descriptor: | Temporin-1Tl | Authors: | Jia, R, McShan, A.C. | Deposit date: | 2024-05-20 | Release date: | 2024-06-05 | Method: | SOLUTION NMR | Cite: | Design and Development of Temporin L Analogues to Inhibit the Main Protease of SARS-CoV-2 To Be Published
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9BXI
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9F5Q
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7AHB
| Acyltransferase domain of the polyketide synthase PpsC of Mycobacterium tuberculosis | Descriptor: | GLYCEROL, Phthiocerol synthesis polyketide synthase type I PpsC, SODIUM ION, ... | Authors: | Faille, A, Mourey, L, Pedelacq, J.D. | Deposit date: | 2020-09-24 | Release date: | 2020-12-09 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Molecular Basis for Extender Unit Specificity of Mycobacterial Polyketide Synthases. Acs Chem.Biol., 15, 2020
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9BG1
| Tri-complex of Compound-3, KRAS G12V, and CypA | Descriptor: | (2R)-N-[(1P,7S,9S,13R,20M)-21-ethyl-20-{2-[(1S)-1-methoxyethyl]pyridin-3-yl}-17,17-dimethyl-8,14-dioxo-15-oxa-4-thia-9,21,27,28-tetraazapentacyclo[17.5.2.1~2,5~.1~9,13~.0~22,26~]octacosa-1(24),2,5(28),19,22,25-hexaen-7-yl]-3-methyl-2-(N-methylacetamido)butanamide (non-preferred name), GTPase KRas, MAGNESIUM ION, ... | Authors: | Tomlinson, A.C.A, Saldajeno-Concar, M, Knox, J.E, Yano, J.K. | Deposit date: | 2024-04-18 | Release date: | 2024-06-12 | Last modified: | 2024-06-26 | Method: | X-RAY DIFFRACTION (1.51 Å) | Cite: | Tri-complex of Compound-3, KRAS G12V, and CypA To be published
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9GBV
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9FW2
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9B0B
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9BTS
| Crystal structure of the bacterioferritin (Bfr) and ferritin (Ftn) heterooligomer complex from Acinetobacter baumannii | Descriptor: | Bacterioferritin (Bfr), Ferritin (Ftn), PROTOPORPHYRIN IX CONTAINING FE, ... | Authors: | Lovell, S, Liu, L, Battaile, K.P, Rivera, M. | Deposit date: | 2024-05-15 | Release date: | 2024-08-14 | Last modified: | 2024-08-21 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | The crystal structure of Acinetobacter baumannii bacterioferritin reveals a heteropolymer of bacterioferritin and ferritin subunits. Sci Rep, 14, 2024
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7APL
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9CRN
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9B9M
| Crystal structure of iron-bound FlcD from Pseudomonas aeruginosa | Descriptor: | FE (II) ION, Pyrroloquinoline quinone (Coenzyme PQQ) biosynthesis protein C | Authors: | Walker, M.E, Grove, T.L, Li, B, Redinbo, M.R. | Deposit date: | 2024-04-02 | Release date: | 2024-07-31 | Last modified: | 2024-09-18 | Method: | X-RAY DIFFRACTION (2.07 Å) | Cite: | Structural Basis for Methine Excision by a Heme Oxygenase-like Enzyme. Acs Cent.Sci., 10, 2024
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9D6J
| Nitrile hydratase BR52K mutant | Descriptor: | Cobalt-containing nitrile hydratase subunit alpha, Cobalt-containing nitrile hydratase subunit beta | Authors: | Miller, C.G, Holz, R.C, Liu, D, Kaley, N. | Deposit date: | 2024-08-15 | Release date: | 2024-08-28 | Method: | X-RAY DIFFRACTION (1.47 Å) | Cite: | Role of second-sphere arginine residues in metal binding and metallocentre assembly in nitrile hydratases. J Inorg Biochem, 256, 2024
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9CE9
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4P1M
| The structure of Escherichia coli ZapA | Descriptor: | CHLORIDE ION, Cell division protein ZapA | Authors: | Kimber, M.S, Roach, E.J, Khursigara, C.M. | Deposit date: | 2014-02-26 | Release date: | 2014-07-16 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Crystal Structure and Site-directed Mutational Analysis Reveals Key Residues Involved in Escherichia coli ZapA Function. J.Biol.Chem., 289, 2014
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9GII
| Jumonji domain-containing protein 2A with crystallization epitope mutation R913A | Descriptor: | GLYCEROL, Lysine-specific demethylase 4A, SULFATE ION | Authors: | Fairhead, M, Strain-Damerell, C, Ye, M, Mackinnon, S.R, Pinkas, D, MacLean, E.M, Koekemoer, L, Damerell, D, Krojer, T, Arrowsmith, C.H, Edwards, A, Bountra, C, Yue, W, Burgess-Brown, N, Marsden, B, von Delft, F, Structural Genomics Consortium (SGC) | Deposit date: | 2024-08-19 | Release date: | 2024-09-04 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | A fast, parallel method for efficiently exploring crystallization behaviour of large numbers of protein variants To be published
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9BHW
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9C6N
| ARP module of the human TIP60 complex | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Actin, cytoplasmic 1, ... | Authors: | Yang, Z, Mameri, A, Florez Ariza, A.J, Cote, J, Nogales, E. | Deposit date: | 2024-06-07 | Release date: | 2024-08-21 | Last modified: | 2024-09-11 | Method: | ELECTRON MICROSCOPY (3.29 Å) | Cite: | Structural insights into the human NuA4/TIP60 acetyltransferase and chromatin remodeling complex. Science, 385, 2024
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9FQA
| Crystal structure of SARS-CoV-2 main protease (MPro) in complex with the covalently bound inhibitor PSB-21101 (compound 30b in publication) | Descriptor: | (5-chloranylpyridin-3-yl) 2-fluoranyl-4-phenylmethoxy-benzoate, BROMIDE ION, MAGNESIUM ION, ... | Authors: | Strater, N, Claff, T, Sylvester, K, Oneto, A, Guetschow, M, Mueller, C.E. | Deposit date: | 2024-06-14 | Release date: | 2024-08-28 | Last modified: | 2024-09-25 | Method: | X-RAY DIFFRACTION (1.47 Å) | Cite: | Nonpeptidic Irreversible Inhibitors of SARS-CoV-2 Main Protease with Potent Antiviral Activity. J.Med.Chem., 67, 2024
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9GJ2
| Crystal structure of human cathepsin S produced in insect cells in complex with ketoamide 13b | Descriptor: | 1,2-ETHANEDIOL, CITRIC ACID, Cathepsin S, ... | Authors: | Falke, S, Karnicar, K, Usenik, A, Lindic, N, Sekirnik, A, Reinke, P.Y.A, Guenther, S, Turk, D, Meents, A. | Deposit date: | 2024-08-20 | Release date: | 2024-09-04 | Method: | X-RAY DIFFRACTION (1.15 Å) | Cite: | Crystal structure of human cathepsin S produced in insect cells in complex with ketoamide 13b To Be Published
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