9FXP
| Crystal structure of BRD4 BD1 with DI00626383. | Descriptor: | 4-methoxy-1,2-benzoxazol-3-amine, Bromodomain-containing protein 4 | Authors: | Bader, G, Reinert, D. | Deposit date: | 2024-07-02 | Release date: | 2024-08-07 | Last modified: | 2024-08-21 | Method: | X-RAY DIFFRACTION (1.88 Å) | Cite: | Probing Protein-Ligand Methyl-pi Interaction Geometries through Chemical Shift Measurements of Selectively Labeled Methyl Groups. J.Med.Chem., 67, 2024
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8YF7
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8YF8
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8YF9
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6G6J
| The crystal structures of Human MYC:MAX bHLHZip complex | Descriptor: | Myc proto-oncogene protein, Protein max, SULFATE ION | Authors: | Allen, M.D, Zinzalla, G. | Deposit date: | 2018-04-01 | Release date: | 2019-04-10 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Crystal Structures and Nuclear Magnetic Resonance Studies of the Apo Form of the c-MYC:MAX bHLHZip Complex Reveal a Helical Basic Region in the Absence of DNA. Biochemistry, 58, 2019
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6G6K
| The crystal structures of Human MYC:MAX bHLHZip complex | Descriptor: | CHLORIDE ION, Myc proto-oncogene protein, Protein max | Authors: | Allen, M.D, Zinzalla, G. | Deposit date: | 2018-04-01 | Release date: | 2019-04-10 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Crystal Structures and Nuclear Magnetic Resonance Studies of the Apo Form of the c-MYC:MAX bHLHZip Complex Reveal a Helical Basic Region in the Absence of DNA. Biochemistry, 58, 2019
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8GVN
| Novel salt-resistant antimicrobial peptide, RR14 | Descriptor: | TRP-LEU-ARG-ARG-ILE-LYS-ALA-TRP-LEU-ARG-ARG-ILE-LYS-ALA | Authors: | Lin, T.L, Tseng, T.S, Fan, P.J. | Deposit date: | 2022-09-15 | Release date: | 2022-11-09 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Deciphering Structure-Function Relationship Unveils Salt-Resistant Mode of Action of a Potent MRSA-Inhibiting Antimicrobial Peptide, RR14. J.Bacteriol., 204, 2022
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8G24
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8G25
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2V1Y
| Structure of a phosphoinositide 3-kinase alpha adaptor-binding domain (ABD) in a complex with the iSH2 domain from p85 alpha | Descriptor: | PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT ALPHA, PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT ALPHA ISOFORM | Authors: | Miled, N, Yan, Y, Hon, W.C, Perisic, O, Zvelebil, M, Inbar, Y, Schneidman-Duhovny, D, Wolfson, H.J, Backer, J.M, Williams, R.L. | Deposit date: | 2007-05-30 | Release date: | 2007-07-24 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Mechanism of Two Classes of Cancer Mutations in the Phosphoinositide 3-Kinase Catalytic Subunit. Science, 317, 2007
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8G26
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8GP7
| Structure of Trioxacarcin A covalently bound to RET G4-DNA | Descriptor: | DNA (5'-D(*GP*GP*GP*GP*CP*GP*GP*GP*GP*CP*GP*GP*GP*GP*CP*GP*GP*GP*GP*T)-3'), Trioxacarcin A, bound form | Authors: | Yin, S, Cao, C. | Deposit date: | 2022-08-25 | Release date: | 2023-09-06 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Trioxacarcin A Interactions with G-Quadruplex DNA Reveal Its Potential New Targets as an Anticancer Agent. J.Med.Chem., 66, 2023
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2W4U
| Isometrically contracting insect asynchronous flight muscle quick frozen after a length step | Descriptor: | ACTIN, ALPHA SKELETAL MUSCLE, TROPOMYOSIN ALPHA-1 CHAIN, ... | Authors: | Wu, S, Liu, J, Reedy, M.C, Tregear, R.T, Winkler, H, Franzini-Armstrong, C, Sasaki, H, Lucaveche, C, Goldman, Y.E, Reedy, M.K, Taylor, K.A. | Deposit date: | 2008-12-02 | Release date: | 2010-08-25 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (35 Å) | Cite: | Structural Changes in Isometrically Contracting Insect Flight Muscle Trapped Following a Mechanical Perturbation. Plos One, 7, 2012
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8G9A
| Crystal structure of a resurrected ancestor (AncRNase) of the pancreatic-type RNases 2 and 3 sub-families | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, SULFATE ION, ... | Authors: | Tran, T.T.Q, Pham, N.T.H, Calmettes, C, Doucet, N. | Deposit date: | 2023-02-21 | Release date: | 2024-02-28 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.03 Å) | Cite: | Ancestral sequence reconstruction dissects structural and functional differences among eosinophil ribonucleases. J.Biol.Chem., 300, 2024
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2WJL
| Bacteriorhodopsin mutant E194D | Descriptor: | Bacteriorhodopsin, RETINAL | Authors: | Potschies, M, Wolf, S, Freier, E, Hofmann, E, Gerwert, K. | Deposit date: | 2009-05-27 | Release date: | 2010-08-25 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Directional proton transfer in membrane proteins achieved through protonated protein-bound water molecules: a proton diode. Angew. Chem. Int. Ed. Engl., 49, 2010
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8HDJ
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8HN3
| Soluble domain of cytochrome c-556 from Chlorobaculum tepidum | Descriptor: | ACETATE ION, Cytochrome c-556, GLYCEROL, ... | Authors: | Kishimoto, H, Azai, C, Yamamoto, T, Mutoh, R, Nakaniwa, T, Tanaka, H, Kurisu, G, Oh-oka, H. | Deposit date: | 2022-12-07 | Release date: | 2023-07-05 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Soluble domains of cytochrome c-556 and Rieske iron-sulfur protein from Chlorobaculum tepidum: Crystal structures and interaction analysis. Curr Res Struct Biol, 5, 2023
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8HN2
| Selenomethionine-labelled soluble domain of Rieske iron-sulfur protein from chlorobaculum tepidum | Descriptor: | Cytochrome b6-f complex iron-sulfur subunit, FE2/S2 (INORGANIC) CLUSTER | Authors: | Kishimoto, H, Mutoh, R, Tanaka, H, Kurisu, G, Oh-oka, H. | Deposit date: | 2022-12-07 | Release date: | 2023-07-05 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Soluble domains of cytochrome c-556 and Rieske iron-sulfur protein from Chlorobaculum tepidum: Crystal structures and interaction analysis. Curr Res Struct Biol, 5, 2023
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6HQC
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8FG6
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8FTQ
| Crystal structure of hRpn13 Pru domain in complex with Ubiquitin and XL44 | Descriptor: | N-(3-{[(3R)-5-fluoro-2-oxo-2,3-dihydro-1H-indol-3-yl]methyl}phenyl)-4-methoxybenzamide, Proteasomal ubiquitin receptor ADRM1, Ubiquitin | Authors: | Walters, K.J, Lu, X, Chandravanshi, M. | Deposit date: | 2023-01-13 | Release date: | 2024-03-27 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | A structure-based designed small molecule depletes hRpn13 Pru and a select group of KEN box proteins. Nat Commun, 15, 2024
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8HR4
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2VWF
| Grb2 SH3C (2) | Descriptor: | GRB2-ASSOCIATED-BINDING PROTEIN 2, GROWTH FACTOR RECEPTOR-BOUND PROTEIN 2 | Authors: | Harkiolaki, M, Tsirka, T, Feller, S.M. | Deposit date: | 2008-06-24 | Release date: | 2009-05-19 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.58 Å) | Cite: | Distinct Binding Modes of Two Epitopes in Gab2 that Interact with the Sh3C Domain of Grb2. Structure, 17, 2009
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8GGG
| RNase A-Adenosine 5'-Hexaphosphate (RNaseA.p6A) | Descriptor: | GLYCEROL, Ribonuclease pancreatic, adenosine 5'-hexaphosphate | Authors: | Park, G, Cummins, C. | Deposit date: | 2023-03-08 | Release date: | 2024-03-13 | Last modified: | 2024-08-07 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | Pentaphosphorylation via the Anhydride of Dihydrogen Pentametaphosphate: Access to Nucleoside Hexa- and Heptaphosphates and Study of Their Interaction with Ribonuclease A. Acs Cent.Sci., 10, 2024
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8GE0
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