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2C52
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BU of 2c52 by Molmil
Structural diversity in CBP p160 complexes
Descriptor: CREB-BINDING PROTEIN, NUCLEAR RECEPTOR COACTIVATOR 1
Authors:Waters, L.C, Yue, B, Veverka, V, Renshaw, P.S, Bramham, J, Matsuda, S, Frenkiel, T, Kelly, G, Muskett, F.W, Carr, M.D, Heery, D.M.
Deposit date:2005-10-25
Release date:2006-03-15
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structural diversity in p160/CREB-binding protein coactivator complexes.
J. Biol. Chem., 281, 2006
4P5K
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BU of 4p5k by Molmil
Structural Basis of Chronic Beryllium Disease: Bridging the Gap Between Allergy and Autoimmunity
Descriptor: HLA class II histocompatibility antigen, DP alpha 1 chain, RAS peptide,HLA class II histocompatibility antigen, ...
Authors:Clayton, G.M, Wang, Y, Crawford, F, Novikov, A, Wimberly, B.T, Kieft, J.S, Falta, M.T, Bowerman, N.A, Marrack, P, Fontenot, A.P, Dai, S, Kappler, J.W.
Deposit date:2014-03-17
Release date:2015-01-21
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:Structural basis of chronic beryllium disease: linking allergic hypersensitivity and autoimmunity.
Cell, 158, 2014
6CPS
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BU of 6cps by Molmil
Crystal structure of the bromodomain of human ATAD2 with a disulfide bridge
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ATPase family AAA domain-containing protein 2, SULFATE ION
Authors:Glass, K.C, Eckenroth, B.E, Carlson, S.
Deposit date:2018-03-14
Release date:2018-12-19
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Disulfide bridge formation influences ligand recognition by the ATAD2 bromodomain.
Proteins, 87, 2019
6P9K
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BU of 6p9k by Molmil
Crystal structure of Mycobacterium tuberculosis KasA in complex with O6G
Descriptor: 3-oxoacyl-ACP synthase, GLYCEROL, ISOPROPYL ALCOHOL, ...
Authors:Capodagli, G.C, Neiditch, M.B.
Deposit date:2019-06-10
Release date:2020-04-01
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.703 Å)
Cite:A Preclinical Candidate Targeting Mycobacterium tuberculosis KasA.
Cell Chem Biol, 27, 2020
5OE2
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BU of 5oe2 by Molmil
CRYSTAL STRUCTURE OF THE BETA-LACTAMASE OXA-245
Descriptor: Beta-lactamase, CHLORIDE ION, SODIUM ION
Authors:Lund, B.A, Leiros, H.K.S.
Deposit date:2017-07-07
Release date:2017-08-02
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure, activity and thermostability investigations of OXA-163, OXA-181 and OXA-245 using biochemical analysis, crystal structures and differential scanning calorimetry analysis.
Acta Crystallogr F Struct Biol Commun, 73, 2017
1E8L
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BU of 1e8l by Molmil
NMR solution structure of hen lysozyme
Descriptor: LYSOZYME
Authors:Schwalbe, H, Grimshaw, S.B, Spencer, A, Buck, M, Boyd, J, Dobson, C.M, Redfield, C, Smith, L.J.
Deposit date:2000-09-27
Release date:2000-10-09
Last modified:2018-01-24
Method:SOLUTION NMR
Cite:A refined solution structure of hen lysozyme determined using residual dipolar coupling data.
Protein Sci., 10, 2001
4WBO
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BU of 4wbo by Molmil
Bovine G Protein Coupled Receptor Kinase 1 in Complex with Amlexanox
Descriptor: 2-amino-7-(1-methylethyl)-5-oxo-5H-chromeno[2,3-b]pyridine-3-carboxylic acid, CHLORIDE ION, Rhodopsin kinase
Authors:Homan, K.T, Tesmer, J.J.G.
Deposit date:2014-09-03
Release date:2014-11-05
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.81 Å)
Cite:Identification and characterization of amlexanox as a g protein-coupled receptor kinase 5 inhibitor.
Molecules, 19, 2014
7B5R
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BU of 7b5r by Molmil
Ubiquitin ligation to F-box protein substrates by SCF-RBR E3-E3 super-assembly: CUL1-RBX1-SKP1-SKP2-CKSHS1-Cyclin A-CDK2-p27
Descriptor: Cullin-1, Cyclin-A2, Cyclin-dependent kinase 2, ...
Authors:Horn-Ghetko, D, Prabu, J.R, Schulman, B.A.
Deposit date:2020-12-07
Release date:2021-02-10
Last modified:2021-03-10
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Ubiquitin ligation to F-box protein targets by SCF-RBR E3-E3 super-assembly.
Nature, 590, 2021
8YC0
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BU of 8yc0 by Molmil
T cell receptor V delta2 V gamma9 in GDN
Descriptor: CHOLESTEROL, T cell receptor delta variable 2,T cell receptor delta constant, T cell receptor gamma variable 9,T cell receptor gamma constant 1, ...
Authors:Xin, W, Huang, B, Chi, X, Xu, M, Zhang, Y, Li, X, Su, Q, Zhou, Q.
Deposit date:2024-02-17
Release date:2024-05-08
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (4.12 Å)
Cite:Structures of human gamma delta T cell receptor-CD3 complex.
Nature, 630, 2024
6CXW
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BU of 6cxw by Molmil
Synaptotagmin 1 C2A beta4 chimera with enhanced PIP2 binding function
Descriptor: Synaptotagmin 1 C2A beta4 chimera
Authors:Sutton, R.B.
Deposit date:2018-04-04
Release date:2019-04-17
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.832 Å)
Cite:Engineering a C2-domain to bind PIP2
To Be Published
7B5L
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BU of 7b5l by Molmil
Ubiquitin ligation to F-box protein substrates by SCF-RBR E3-E3 super-assembly: NEDD8-CUL1-RBX1-SKP1-SKP2-CKSHS1-Cyclin A-CDK2-p27-UBE2L3~Ub~ARIH1. Transition State 1
Descriptor: 5-azanylpentan-2-one, Cullin-1, Cyclin-A2, ...
Authors:Horn-Ghetko, D, Prabu, J.R, Schulman, B.A.
Deposit date:2020-12-04
Release date:2021-02-10
Last modified:2021-03-10
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Ubiquitin ligation to F-box protein targets by SCF-RBR E3-E3 super-assembly.
Nature, 590, 2021
4UUR
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BU of 4uur by Molmil
Cold-adapted truncated hemoglobin from the Antarctic marine bacterium Pseudoalteromonas haloplanktis TAC125
Descriptor: PROTOPORPHYRIN IX CONTAINING FE, PUTATIVE HEMOGLOBIN-LIKE OXYGEN-BINDING PROTEIN
Authors:Pesce, A, Giordano, D, Riccio, A, Nardini, M, Caldelli, E, Howes, B, Bustamante, J.P, Boechi, L, Estrin, D, di Prisco, G, Smulevich, G, Verde, C, Bolognesi, M.
Deposit date:2014-07-31
Release date:2015-06-10
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Structural Flexibility of the Heme Cavity in the Cold-Adapted Truncated Hemoglobin from the Antarctic Marine Bacterium Pseudoalteromonas Haloplanktis Tac125.
FEBS J., 282, 2015
1EH1
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BU of 1eh1 by Molmil
RIBOSOME RECYCLING FACTOR FROM THERMUS THERMOPHILUS
Descriptor: RIBOSOME RECYCLING FACTOR
Authors:Toyoda, T, Tin, O.F, Ito, K, Fujiwara, T, Kumasaka, T, Yamamoto, M, Garber, M.B, Nakamura, Y.
Deposit date:2000-02-18
Release date:2000-11-15
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure combined with genetic analysis of the Thermus thermophilus ribosome recycling factor shows that a flexible hinge may act as a functional switch.
RNA, 6, 2000
5A4F
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BU of 5a4f by Molmil
The mechanism of Hydrogen Activation by NiFe-hydrogenases.
Descriptor: CARBONMONOXIDE-(DICYANO) IRON, CHLORIDE ION, FE3-S4 CLUSTER, ...
Authors:Evans, R.M, Brooke, E.J, Wehlin, S.A.M, Nomerotskaia, E, Sargent, F, Carr, S.B, Phillips, S.E.V, Armstrong, F.A.
Deposit date:2015-06-09
Release date:2015-11-25
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Mechanism of hydrogen activation by [NiFe] hydrogenases.
Nat. Chem. Biol., 12, 2016
7B5M
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BU of 7b5m by Molmil
Ubiquitin ligation to F-box protein substrates by SCF-RBR E3-E3 super-assembly: CUL1-RBX1-SKP1-SKP2-CKSHS1-p27~Ub~ARIH1. Transition State 2
Descriptor: Cullin-1, Cyclin-dependent kinase inhibitor 1B, Cyclin-dependent kinases regulatory subunit 1, ...
Authors:Horn-Ghetko, D, Prabu, J.R, Schulman, B.A.
Deposit date:2020-12-05
Release date:2021-02-17
Last modified:2021-03-10
Method:ELECTRON MICROSCOPY (3.91 Å)
Cite:Ubiquitin ligation to F-box protein targets by SCF-RBR E3-E3 super-assembly.
Nature, 590, 2021
2BEG
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BU of 2beg by Molmil
3D Structure of Alzheimer's Abeta(1-42) fibrils
Descriptor: Amyloid beta A4 protein
Authors:Luhrs, T, Ritter, C, Adrian, M, Riek-Loher, D, Bohrmann, B, Dobeli, H, Schubert, D, Riek, R.
Deposit date:2005-10-24
Release date:2005-11-22
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:3D structure of Alzheimer's amyloid-{beta}(1-42) fibrils.
Proc.Natl.Acad.Sci.Usa, 102, 2005
6D0A
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BU of 6d0a by Molmil
Crystal structure of Kynurenine Aminotransferase-II in apo-form, at 1.47 A resolution
Descriptor: Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial
Authors:Jayawickrama, G.S, Sun, G, Nematollahi, A, Church, W.B.
Deposit date:2018-04-10
Release date:2018-05-02
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.46809423 Å)
Cite:Crystal structure of Kynurenine Aminotransferase-II in apo-form
To Be Published
6P08
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BU of 6p08 by Molmil
Ternary structure of the E52D mutant of ANT-4'' with Neomycin, AMP and Pyrophosphate
Descriptor: ADENOSINE MONOPHOSPHATE, Kanamycin nucleotidyltransferase, MAGNESIUM ION, ...
Authors:Selvaraj, B, Cuneo, M.J.
Deposit date:2019-05-16
Release date:2020-01-29
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:"Catch and Release": a Variation of the Archetypal Nucleotidyl Transfer Reaction
Acs Catalysis, 10, 2020
5A1I
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BU of 5a1i by Molmil
The structure of Human MAT2A in complex with SAM, Adenosine, Methionine and PPNP.
Descriptor: (DIPHOSPHONO)AMINOPHOSPHONIC ACID, 1,2-ETHANEDIOL, ADENOSINE, ...
Authors:Murray, B, Antonyuk, S.V, Marina, A, Lu, S.C, Mato, J.M, Hasnain, S.S, Rojas, A.L.
Deposit date:2015-04-30
Release date:2016-03-09
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.09 Å)
Cite:Crystallography Captures Catalytic Steps in Human Methionine Adenosyltransferase Enzymes.
Proc.Natl.Acad.Sci.USA, 113, 2016
2BDM
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BU of 2bdm by Molmil
Structure of Cytochrome P450 2B4 with Bound Bifonazole
Descriptor: 1-[PHENYL-(4-PHENYLPHENYL)-METHYL]IMIDAZOLE, 5-CYCLOHEXYL-1-PENTYL-BETA-D-MALTOSIDE, Cytochrome P450 2B4, ...
Authors:Zhao, Y, White, M.A, Muralidhara, B.K, Sun, L, Halpert, J.R, Stout, C.D.
Deposit date:2005-10-20
Release date:2005-12-27
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of microsomal cytochrome P450 2B4 complexed with the antifungal drug bifonazole: insight into P450 conformational plasticity and membrane interaction.
J.Biol.Chem., 281, 2006
4UP4
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BU of 4up4 by Molmil
Structure of the recombinant lectin PVL from Psathyrella velutina in complex with GlcNAcb-D-1,3Galactoside
Descriptor: 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-beta-D-galactopyranose, ...
Authors:Audfray, A, Beljoudi, M, Hurbin, A, Varrot, A, Breiman, A, Busser, B, Lependu, J, Coll, J.L, Imberty, A.
Deposit date:2014-06-12
Release date:2015-01-28
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:A Recombinant Fungal Lectin for Labeling Truncated Glycans on Human Cancer Cells.
Plos One, 10, 2015
3LB3
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BU of 3lb3 by Molmil
Two-site competitive inhibition in dehaloperoxidase-hemoglobin
Descriptor: 4-chlorophenol, Dehaloperoxidase A, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:de Serrano, V.S, Franzen, S, Thompson, M.K, Davis, M.F, Nicoletti, F.P, Howes, B.D, Smulevich, G.
Deposit date:2010-01-07
Release date:2010-11-24
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Internal binding of halogenated phenols in dehaloperoxidase-hemoglobin inhibits peroxidase function.
Biophys.J., 99, 2010
6CTZ
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BU of 6ctz by Molmil
Structure of the GDP and kanamycin complex of APH(2")-IIia
Descriptor: CHLORIDE ION, GUANOSINE-5'-DIPHOSPHATE, Gentamicin resistance protein, ...
Authors:Smith, C.A, Vakulenko, S.B.
Deposit date:2018-03-23
Release date:2019-03-27
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.34 Å)
Cite:Structural basis for the diversity of the mechanism of nucleotide hydrolysis by the aminoglycoside-2''-phosphotransferases
Acta Crystallogr.,Sect.D, 75, 2019
5A74
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BU of 5a74 by Molmil
Crystal structure of the homing endonuclease I-CvuI in complex with its target (Sro1.3) in the presence of 2 mM Mn
Descriptor: 10MER DNA, 5'-D(*GP*AP*CP*GP*TP*TP*CP*TP*GP*AP)-3', 14MER DNA, ...
Authors:Molina, R, Redondo, P, LopezMendez, B, Villate, M, Merino, N, Blanco, F.J, Valton, J, Grizot, S, Duchateau, P, Prieto, J, Montoya, G.
Deposit date:2015-07-02
Release date:2015-09-23
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structure of the Homing Endonuclease I-Cvui Provides a New Template for Genome Modification
J.Biol.Chem., 290, 2015
6WBH
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BU of 6wbh by Molmil
Crystal structure of mRECK(CC4) in fusion with engineered MBP at medium resolution
Descriptor: CHLORIDE ION, Maltodextrin-binding protein,Reversion-inducing cysteine-rich protein with Kazal motifs fusion, ZINC ION, ...
Authors:Chang, T.H, Hsieh, F.L, Gabelli, S.B, Nathans, J.
Deposit date:2020-03-26
Release date:2020-06-17
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.455 Å)
Cite:Structure of the RECK CC domain, an evolutionary anomaly.
Proc.Natl.Acad.Sci.USA, 117, 2020

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