2QOJ
| Coevolution of a homing endonuclease and its host target sequence | Descriptor: | I-AniI DNA target seq1, I-AniI DNA target seq2, LAGLIDADG endonuclease, ... | Authors: | Scalley-Kim, M, McConnell Smith, A, Stoddard, B.L. | Deposit date: | 2007-07-20 | Release date: | 2008-11-11 | Last modified: | 2021-10-20 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Coevolution of a homing endonuclease and its host target sequence. J.Mol.Biol., 372, 2007
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3TGE
| A novel series of potent and selective PDE5 inhibitor1 | Descriptor: | 7-(6-methoxypyridin-3-yl)-3-{[2-(morpholin-4-yl)ethyl]amino}-1-(2-propoxyethyl)pyrido[3,4-b]pyrazin-2(1H)-one, MAGNESIUM ION, ZINC ION, ... | Authors: | Han, S. | Deposit date: | 2011-08-17 | Release date: | 2011-11-09 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.96 Å) | Cite: | Investigation of the pyrazinones as PDE5 inhibitors: Evaluation of regioisomeric projections into the solvent region. Bioorg.Med.Chem.Lett., 21, 2011
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1MXL
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3Q8C
| Crystal structure of Protective Antigen W346F (pH 5.5) | Descriptor: | CALCIUM ION, Protective antigen | Authors: | Lovell, S, Battaile, K.P, Rajapaksha, M, Janowiak, B.E, Andra, K.K, Bann, J.G. | Deposit date: | 2011-01-06 | Release date: | 2012-02-15 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | pH effects on binding between the anthrax protective antigen and the host cellular receptor CMG2. Protein Sci., 21, 2012
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2L28
| Solution structure of lactobacillus casei dihydrofolate reductase apo-form, 25 conformers | Descriptor: | Dihydrofolate reductase | Authors: | Polshakov, V.I, Birdsall, B, Feeney, J. | Deposit date: | 2010-08-13 | Release date: | 2011-04-06 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | NMR Structures of Apo L. casei Dihydrofolate Reductase and Its Complexes with Trimethoprim and NADPH: Contributions to Positive Cooperative Binding from Ligand-Induced Refolding, Conformational Changes, and Interligand Hydrophobic Interactions. Biochemistry, 50, 2011
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2AM2
| sp protein ligand 2 | Descriptor: | 2-CHLORO-N-(3-CYANO-5,6-DIHYDRO-4H-CYCLOPENTA[B]THIOPHEN-2-YL)-5-DIETHYLSULFAMOYL-BENZAMIDE, UDP-N-acetylmuramoylalanine-D-glutamyl-lysine-D-alanyl-D-alanine ligase, MurF protein | Authors: | Longenecker, K.L, Stamper, G.F, Hajduk, P.J, Fry, E.H, Jakob, C.G, Harlan, J.E, Edalji, R, Bartley, D.M, Walter, K.A, Solomon, L.R. | Deposit date: | 2005-08-08 | Release date: | 2006-01-24 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure of MurF from Streptococcus pneumoniae co-crystallized with a small molecule inhibitor exhibits interdomain closure Protein Sci., 14, 2005
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3Q8A
| Crystal structure of WT Protective Antigen (pH 5.5) | Descriptor: | CALCIUM ION, Protective antigen | Authors: | Rajapaksha, M, Lovell, S, Janowiak, B.E, Andra, K.K, Battaile, K.P, Bann, J.G. | Deposit date: | 2011-01-06 | Release date: | 2012-01-18 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (3.129 Å) | Cite: | pH effects on binding between the anthrax protective antigen and the host cellular receptor CMG2. Protein Sci., 21, 2012
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3QDH
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3Q8B
| Crystal structure of WT Protective Antigen (pH 9.0) | Descriptor: | CALCIUM ION, Protective antigen | Authors: | Lovell, S, Battaile, K.P, Rajapaksha, M, Janowiak, B.E, Andra, K.K, Bann, J.G. | Deposit date: | 2011-01-06 | Release date: | 2012-02-15 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | pH effects on binding between the anthrax protective antigen and the host cellular receptor CMG2. Protein Sci., 21, 2012
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1JBZ
| CRYSTAL STRUCTURE ANALYSIS OF A DUAL-WAVELENGTH EMISSION GREEN FLUORESCENT PROTEIN VARIANT AT HIGH PH | Descriptor: | 1,2-ETHANEDIOL, GREEN FLUORESCENT PROTEIN, MAGNESIUM ION | Authors: | Hanson, G.T, McAnaney, T.B, Park, E.S, Rendell, M.E.P, Yarbrough, D.K, Chu, S, Xi, L, Boxer, S.G, Montrose, M.H, Remington, S.J. | Deposit date: | 2001-06-07 | Release date: | 2003-01-07 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Green Fluorescent Protein Variants as Ratiometric Dual Emission pH Sensors. 1. Structural Characterization and Preliminary Application. Biochemistry, 41, 2002
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1WT1
| Mutant ABO(H) blood group glycosyltransferase with bound UDP and acceptor | Descriptor: | Histo-blood group ABO system transferase, MERCURY (II) ION, URIDINE-5'-DIPHOSPHATE, ... | Authors: | Lee, H.J, Barry, C.H, Borisova, S.N, Seto, N.O.L, Zheng, R.B, Blancher, A, Evans, S.V, Palcic, M.M. | Deposit date: | 2004-11-12 | Release date: | 2004-12-07 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Structural basis for the inactivity of human blood group o2 glycosyltransferase J.Biol.Chem., 280, 2005
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1AGL
| STRUCTURE OF A DNA-BISDAUNOMYCIN COMPLEX | Descriptor: | 4-METHYLBENZYL-N-BIS[DAUNOMYCIN], DNA (5'-D(*CP*GP*AP*TP*CP*G)-3') | Authors: | Hu, G.G, Shui, X, Leng, F, Priebe, W, Chaires, J.B, Williams, L.D. | Deposit date: | 1997-03-25 | Release date: | 1997-04-29 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure of a DNA-bisdaunomycin complex. Biochemistry, 36, 1997
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1WT2
| Mutant human ABO(H) blood group glycosyltransferase A with bound UDP and inhibitor | Descriptor: | Histo-blood group ABO system transferase, MERCURY (II) ION, URIDINE-5'-DIPHOSPHATE, ... | Authors: | Lee, H.J, Barry, C.H, Borisova, S.N, Seto, N.O.L, Zheng, R.B, Blancher, A, Evans, S.V, Palcic, M.M. | Deposit date: | 2004-11-12 | Release date: | 2004-12-07 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural basis for the inactivity of human blood group o2 glycosyltransferase J.Biol.Chem., 280, 2005
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1X41
| Solution structure of the Myb-like DNA binding domain of human Transcriptional adaptor 2-like, isoform B | Descriptor: | Transcriptional adaptor 2-like, isoform b | Authors: | Sasagawa, A, Sato, M, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2005-05-12 | Release date: | 2005-11-12 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the Myb-like DNA binding domain of human Transcriptional adaptor 2-like, isoform B To be Published
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1DWU
| Ribosomal protein L1 | Descriptor: | RIBOSOMAL PROTEIN L1 | Authors: | Tishchenko, S.V, Nevskaya, N.A, Pavelyev, M.N, Nikonov, S.V, Garber, M.B, Piendl, W. | Deposit date: | 1999-12-13 | Release date: | 2000-12-07 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure of Ribosomal Protein L1 from Methanococcus Thermolithotrophicus. Functionally Important Structural Invariants on the L1 Surface Acta Crystallogr.,Sect.D, 58, 2002
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1WSZ
| Mutant human ABO(H) blood group transferase A | Descriptor: | Histo-blood group ABO system transferase, MERCURY (II) ION | Authors: | Lee, H.J, Barry, C.H, Borisova, S.N, Seto, N.O.L, Zheng, R.B, Blancher, A, Evans, S.V, Palcic, M.M. | Deposit date: | 2004-11-12 | Release date: | 2004-12-07 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.59 Å) | Cite: | Structural basis for the inactivity of human blood group o2 glycosyltransferase J.Biol.Chem., 280, 2005
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2B5Y
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3ULQ
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2P7C
| Solution structure of the bacillus licheniformis BlaI monomeric form in complex with the blaP half-operator. | Descriptor: | Penicillinase repressor, Strand 1 of Twelve base-pair DNA, Strand 2 of Twelve base-pair DNA | Authors: | Boudet, J, Duval, V, Van Melckebeke, H, Blackledge, M, Amoroso, A, Joris, B, Simorre, J.-P. | Deposit date: | 2007-03-20 | Release date: | 2007-06-12 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Conformational and thermodynamic changes of the repressor/DNA operator complex upon monomerization shed new light on regulation mechanisms of bacterial resistance against beta-lactam antibiotics. Nucleic Acids Res., 35, 2007
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2D0E
| Substrate assited in Oxygen Activation in Cytochrome P450 158A2 | Descriptor: | 2-HYDROXYNAPHTHOQUINONE, PROTOPORPHYRIN IX CONTAINING FE, putative cytochrome P450 | Authors: | Zhao, B, Waterman, M.R. | Deposit date: | 2005-08-02 | Release date: | 2005-10-25 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Role of active site water molecules and substrate hydroxyl groups in oxygen activation by cytochrome P450 158A2: a new mechanism of proton transfer J.Biol.Chem., 280, 2005
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1WT3
| Mutant human ABO(H) blood group glycosyltransferase with bound UDP and acceptor | Descriptor: | Histo-blood group ABO system transferase, MERCURY (II) ION, URIDINE-5'-DIPHOSPHATE, ... | Authors: | Lee, H.J, Barry, C.H, Borisova, S.N, Seto, N.O.L, Zheng, R.B, Blancher, A, Evans, S.V, Palcic, M.M. | Deposit date: | 2004-11-12 | Release date: | 2004-12-03 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural basis for the inactivity of human blood group o2 glycosyltransferase J.Biol.Chem., 280, 2005
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2DJ4
| Solution structure of the 13th filamin domain from human Filamin-B | Descriptor: | Filamin-B | Authors: | Tomizawa, T, Koshiba, S, Watanabe, S, Harada, T, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2006-03-31 | Release date: | 2006-10-01 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the 13th filamin domain from human Filamin-B To be Published
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2DIC
| Solution structure of the 12th filamin domain from human Filamin-B | Descriptor: | Filamin-B | Authors: | Tomizawa, T, Koshiba, S, Watanabe, S, Harada, T, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2006-03-29 | Release date: | 2006-09-29 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the 12th filamin domain from human Filamin-B To be Published
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2DMB
| Solution structure of the 15th Filamin domain from human Filamin-B | Descriptor: | Filamin-B | Authors: | Tomizawa, T, Tochio, N, Koshiba, S, Watanabe, S, Harada, T, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2006-04-20 | Release date: | 2006-10-20 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the 15th Filamin domain from human Filamin-B To be Published
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1ZA0
| X-ray structure of putative acyl-ACP desaturase DesA2 from Mycobacterium tuberculosis H37Rv | Descriptor: | 1,2-ETHANEDIOL, MANGANESE (II) ION, POSSIBLE ACYL-[ACYL-CARRIER PROTEIN] DESATURASE DESA2 (ACYL-[ACP] DESATURASE) (STEAROYL-ACP DESATURASE) | Authors: | Dyer, H.D, Lyle, K.S, Rayment, I, Fox, B.G. | Deposit date: | 2005-04-05 | Release date: | 2005-06-07 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | X-ray structure of putative acyl-ACP desaturase DesA2 from Mycobacterium tuberculosis H37Rv. Protein Sci., 14, 2005
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