PDB: 72703 resultsInfo pagesStatus searchChemie searchBIRD

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6PIF	V. cholerae TniQ-Cascade complex, open conformation Descriptor: Cas7, type I-F CRISPR-associated protein, TniQ monomer 1, ... Authors: Halpin-Healy, T, Klompe, S, Sternberg, S.H. Deposit date: 2019-06-26 Release date: 2019-10-02 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Structural basis of DNA targeting by a transposon-encoded CRISPR-Cas system. Nature, 577, 2020
6D3X	Highly Potent and Selective Plasmin Inhibitors Based on the Sunflower Trypsin Inhibitor-1 Scaffold Attenuate Fibrinolysis in Plasma Descriptor: Plasminogen, Trypsin inhibitor 1 Authors: Law, R.H.P, Wu, G. Deposit date: 2018-04-17 Release date: 2019-01-23 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Highly Potent and Selective Plasmin Inhibitors Based on the Sunflower Trypsin Inhibitor-1 Scaffold Attenuate Fibrinolysis in Plasma. J. Med. Chem., 62, 2019
2UXW	Crystal structure of human very long chain acyl-CoA dehydrogenase (ACADVL) Descriptor: 1,2-ETHANEDIOL, FLAVIN-ADENINE DINUCLEOTIDE, TRANS DELTA2 PALMITENOYL-COENZYMEA, ... Authors: Pike, A.C.W, Hozjan, V, Smee, C, Berridge, G, Burgess, N, Salah, E, Bunkoczi, G, Uppenberg, J, Ugochukwu, E, von Delft, F, Arrowsmith, C.H, Edwards, A, Weigelt, J, Sundstrom, M, Oppermann, U. Deposit date: 2007-03-30 Release date: 2007-05-01 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (1.45 Å) Cite: Crystal Structure of Human Very Long Chain Acyl- Coa Dehydrogenase (Acadvl) To be Published
8Y8D	Structure of HCoV-HKU1C spike in the inactive-1up conformation Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... Authors: Lu, Y.C, Zhang, X, Wang, H.F, Sun, L, Yang, H.T. Deposit date: 2024-02-06 Release date: 2024-07-17 Last modified: 2024-08-28 Method: ELECTRON MICROSCOPY (3.41 Å) Cite: TMPRSS2 and glycan receptors synergistically facilitate coronavirus entry. Cell, 187, 2024
8Y8I	Structure of HCoV-HKU1C spike in the glycan-activated-3up conformation Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein Authors: Lu, Y.C, Zhang, X, Wang, H.F, Sun, L, Yang, H.T. Deposit date: 2024-02-06 Release date: 2024-07-17 Last modified: 2024-08-28 Method: ELECTRON MICROSCOPY (3.58 Å) Cite: TMPRSS2 and glycan receptors synergistically facilitate coronavirus entry. Cell, 187, 2024
6PGP	Crystal structure of human KRAS G12C covalently bound to a quinazolinone inhibitor Descriptor: 6-chloro-7-(2-fluoro-6-hydroxyphenyl)-4-(4-propanoylpiperazin-1-yl)-1-[2-(propan-2-yl)phenyl]quinazolin-2(1H)-one, CALCIUM ION, GTPase KRas, ... Authors: Mohr, C, Whittington, D.A. Deposit date: 2019-06-24 Release date: 2019-12-25 Last modified: 2020-01-22 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Discovery of a Covalent Inhibitor of KRASG12C(AMG 510) for the Treatment of Solid Tumors. J.Med.Chem., 63, 2020
5IQE	Aminoglycoside Phosphotransferase (2'')-Ia (CTD of AAC(6')-Ie/APH(2'')-Ia) in complex with GMPPNP, Magnesium, and Neomycin B Descriptor: Bifunctional AAC/APH, GLYCEROL, MAGNESIUM ION, ... Authors: Caldwell, S.J, Berghuis, A.M. Deposit date: 2016-03-10 Release date: 2016-05-25 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Antibiotic Binding Drives Catalytic Activation of Aminoglycoside Kinase APH(2)-Ia. Structure, 24, 2016
8Y8C	Structure of HCoV-HKU1C spike in the inactive-closed conformation Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein Authors: Lu, Y.C, Zhang, X, Wang, H.F, Sun, L, Yang, H.T. Deposit date: 2024-02-06 Release date: 2024-07-17 Last modified: 2024-08-28 Method: ELECTRON MICROSCOPY (2.95 Å) Cite: TMPRSS2 and glycan receptors synergistically facilitate coronavirus entry. Cell, 187, 2024
5IJ9	Cryo EM density of microtubule assembled from human TUBB3-D417H mutant Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... Authors: Ti, S.C, Pamula, M.C, Howes, S.C, Duellberg, C, Cade, N.I, Kleiner, R.E, Forth, S, Surrey, T, Nogales, E, Kapoor, T.M. Deposit date: 2016-03-01 Release date: 2016-04-20 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: Mutations in Human Tubulin Proximal to the Kinesin-Binding Site Alter Dynamic Instability at Microtubule Plus- and Minus-Ends. Dev.Cell, 37, 2016
8Y89	Structure of HCoV-HKU1C spike in the functionally anchored-3up conformation with 2TMPRSS2 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... Authors: Lu, Y.C, Wang, H.F, Zhang, X, Liu, X.C, Sun, L, Yang, H.T. Deposit date: 2024-02-06 Release date: 2024-07-17 Last modified: 2024-08-28 Method: ELECTRON MICROSCOPY (3.32 Å) Cite: TMPRSS2 and glycan receptors synergistically facilitate coronavirus entry. Cell, 187, 2024
8Y8E	Structure of HCoV-HKU1C spike in the inactive-2up conformation Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein Authors: Lu, Y.C, Zhang, X, Wang, H.F, Sun, L, Yang, H.T. Deposit date: 2024-02-06 Release date: 2024-07-17 Last modified: 2024-08-28 Method: ELECTRON MICROSCOPY (3.62 Å) Cite: TMPRSS2 and glycan receptors synergistically facilitate coronavirus entry. Cell, 187, 2024
8Y88	Structure of HCoV-HKU1C spike in the functionally anchored-2up conformation with 2TMPRSS2 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... Authors: Lu, Y.C, Zhang, X, Wang, H.F, Liu, X.C, Sun, L, Yang, H.T. Deposit date: 2024-02-06 Release date: 2024-07-17 Last modified: 2024-08-28 Method: ELECTRON MICROSCOPY (3.03 Å) Cite: TMPRSS2 and glycan receptors synergistically facilitate coronavirus entry. Cell, 187, 2024
8Y7X	Structure of HCoV-HKU1A spike in the functionally anchored-3up conformation with 3TMPRSS2 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... Authors: Lu, Y.C, Zhang, X, Wang, H.F, Liu, X.C, Sun, L, Yang, H.T. Deposit date: 2024-02-05 Release date: 2024-07-17 Last modified: 2024-08-28 Method: ELECTRON MICROSCOPY (3.09 Å) Cite: TMPRSS2 and glycan receptors synergistically facilitate coronavirus entry. Cell, 187, 2024
7NR1	Crystal structure of holo-S116A mutant of Hydroxy ketone aldolase (SwHKA) from Sphingomonas wittichii RW1 Descriptor: HpcH/HpaI aldolase, MAGNESIUM ION Authors: Justo, I, Marsden, S.R, Hanefeld, U, Bento, I. Deposit date: 2021-03-02 Release date: 2022-09-21 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Substrate Induced Movement of the Metal Cofactor between Active and Resting State. Angew.Chem.Int.Ed.Engl., 61, 2022
7NUJ	Crystal structure of holo-SwHPA-Mg (hydroxy ketone aldolase) from Sphingomonas wittichii RW1 Descriptor: HpcH/HpaI aldolase, MAGNESIUM ION Authors: Laustsen, J, Justo, I, Marsden, S.R, Hanefeld, U, Bento, I. Deposit date: 2021-03-12 Release date: 2022-09-21 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Substrate Induced Movement of the Metal Cofactor between Active and Resting State. Angew.Chem.Int.Ed.Engl., 61, 2022
8Y8G	Structure of HCoV-HKU1C spike in the glycan-activated-1up conformation Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... Authors: Lu, Y.C, Zhang, X, Wang, H.F, Sun, L, Yang, H.T. Deposit date: 2024-02-06 Release date: 2024-07-17 Last modified: 2024-08-28 Method: ELECTRON MICROSCOPY (3.23 Å) Cite: TMPRSS2 and glycan receptors synergistically facilitate coronavirus entry. Cell, 187, 2024
7O5R	Crystal structure of holo-SwHPA-Mn (hydroxyketoacid aldolase) from Sphingomonas wittichii RW1 Descriptor: BROMIDE ION, MANGANESE (II) ION, POTASSIUM ION, ... Authors: Laustsen, J, Justo, I, Marsden, S.R, Hanefeld, U, Bento, I. Deposit date: 2021-04-09 Release date: 2022-10-26 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Substrate Induced Movement of the Metal Cofactor between Active and Resting State. Angew.Chem.Int.Ed.Engl., 61, 2022
7O9R	Crystal structure of holo-H44A mutant of Hydroxy ketone aldolase (SwHKA) from Sphingomonas wittichii RW1 Descriptor: BROMIDE ION, DI(HYDROXYETHYL)ETHER, HpcH/HpaI aldolase, ... Authors: Laustsen, J, Justo, I, Marsden, S.R, Hanefeld, U, Bento, I. Deposit date: 2021-04-16 Release date: 2022-10-26 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Substrate Induced Movement of the Metal Cofactor between Active and Resting State. Angew.Chem.Int.Ed.Engl., 61, 2022
8Y87	Structure of HCoV-HKU1C spike in the functionally anchored-1up conformation with 1TMPRSS2 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... Authors: Lu, Y.C, Zhang, X, Wang, H.F, Liu, X.C, Sun, L, Yang, H.T. Deposit date: 2024-02-06 Release date: 2024-07-17 Last modified: 2024-08-28 Method: ELECTRON MICROSCOPY (3.26 Å) Cite: TMPRSS2 and glycan receptors synergistically facilitate coronavirus entry. Cell, 187, 2024
6JO0	Crystal structure of the DTS-motif rhodopsin from Phaeocystis globosa virus 12T Descriptor: (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, DECANE, DODECANE, ... Authors: Hosaka, T, Kimura-Someya, T, Shirouzu, M. Deposit date: 2019-03-19 Release date: 2019-10-02 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.651 Å) Cite: A distinct lineage of giant viruses brings a rhodopsin photosystem to unicellular marine predators. Proc.Natl.Acad.Sci.USA, 116, 2019
7O5W	Crystal structure of holo-F210W mutant of Hydroxy ketone aldolase (SwHKA)from Sphingomonas wittichii RW1 Descriptor: BROMIDE ION, DI(HYDROXYETHYL)ETHER, HpcH/HpaI aldolase, ... Authors: Laustsen, J, Justo, I, Marsden, S.R, Hanefeld, U, Bento, I. Deposit date: 2021-04-09 Release date: 2022-10-26 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.2 Å) Cite: Substrate Induced Movement of the Metal Cofactor between Active and Resting State. Angew.Chem.Int.Ed.Engl., 61, 2022
8Y8B	Local structure of HCoV-HKU1C spike in complex with TMPRSS2 and glycan Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... Authors: Wang, H.F, Zhang, X, Lu, Y.C, Liu, X.C, Sun, L, Yang, H.T. Deposit date: 2024-02-06 Release date: 2024-07-17 Last modified: 2024-08-28 Method: ELECTRON MICROSCOPY (3.01 Å) Cite: TMPRSS2 and glycan receptors synergistically facilitate coronavirus entry. Cell, 187, 2024
7OBU	Crystal structure of holo-F210W mutant of Hydroxy ketone aldolase (SwHKA) from Sphingomonas wittichii RW1, with the active site in the resting and the active state Descriptor: 3-HYDROXYPYRUVIC ACID, HpcH/HpaI aldolase, MAGNESIUM ION, ... Authors: Laustsen, J, Justo, I, Marsden, S.R, Hanefeld, U, Bento, I. Deposit date: 2021-04-23 Release date: 2022-10-26 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.2 Å) Cite: Substrate Induced Movement of the Metal Cofactor between Active and Resting State. Angew.Chem.Int.Ed.Engl., 61, 2022
7O87	Crystal structure of holo-F210W mutant of Hydroxy ketone aldolase (SwHKA) from Sphingomonas wittichii RW1 in complex with hydroxypyruvate Descriptor: 3-HYDROXYPYRUVIC ACID, BROMIDE ION, DI(HYDROXYETHYL)ETHER, ... Authors: Laustsen, J, Justo, I, Marsden, S.R, Hanefeld, U, Bento, I. Deposit date: 2021-04-14 Release date: 2022-10-26 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Substrate Induced Movement of the Metal Cofactor between Active and Resting State. Angew.Chem.Int.Ed.Engl., 61, 2022
8Y8A	Structure of HCoV-HKU1C spike in the functionally anchored-3up conformation with 3TMPRSS2 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... Authors: Lu, Y.C, Zhang, X, Wang, H.F, Liu, X.C, Sun, L, Yang, H.T. Deposit date: 2024-02-06 Release date: 2024-07-17 Last modified: 2024-08-28 Method: ELECTRON MICROSCOPY (3.19 Å) Cite: TMPRSS2 and glycan receptors synergistically facilitate coronavirus entry. Cell, 187, 2024

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