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7N3V
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Crystal structure of Mycobacterium smegmatis LmcA
Descriptor: GLYCEROL, LmcA, SULFATE ION
Authors:Patel, O, Lucet, I, Panjikar, S.
Deposit date:2021-06-02
Release date:2022-04-13
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Crystal structure of the putative cell-wall lipoglycan biosynthesis protein LmcA from Mycobacterium smegmatis.
Acta Crystallogr D Struct Biol, 78, 2022
6C67
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Mycobacterium tuberculosis adenosine kinase bound to iodotubercidin
Descriptor: (2R,3R,4S,5R)-2-(4-AMINO-5-IODO-7H-PYRROLO[2,3-D]PYRIMIDIN-7-YL)-5-(HYDROXYMETHYL)TETRAHYDROFURAN-3,4-DIOL, Adenosine kinase, GLYCEROL, ...
Authors:Crespo, R.A, TB Structural Genomics Consortium (TBSGC)
Deposit date:2018-01-17
Release date:2019-05-01
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.11 Å)
Cite:Structure-Guided Drug Design of 6-Substituted Adenosine Analogues as Potent Inhibitors of Mycobacterium tuberculosis Adenosine Kinase.
J.Med.Chem., 62, 2019
5ZVJ
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BU of 5zvj by Molmil
Crystal structure of HtrA1 from Mycobacterium tuberculosis
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Serine protease
Authors:Khundrakpam, H.S, Yadav, S, Kumar, D, Biswal, B.K.
Deposit date:2018-05-10
Release date:2018-09-05
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The crystal structure of an essential high-temperature requirement protein HtrA1 (Rv1223) from Mycobacterium tuberculosis reveals its unique features.
Acta Crystallogr D Struct Biol, 74, 2018
6YRK
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BU of 6yrk by Molmil
P140-P110 complex fitted into the cryo-electron density map of the heterodimer
Descriptor: Adhesin P1, Mgp-operon protein 3
Authors:Scheffer, M.P, Aparicio, D.
Deposit date:2020-04-20
Release date:2020-06-24
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Structure and mechanism of the Nap adhesion complex from the human pathogen Mycoplasma genitalium.
Nat Commun, 11, 2020
5L6G
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Xylooligosaccharide oxidase from Myceliophthora thermophila C1 in complex with Xylose
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, FAD linked oxidase-like protein, ...
Authors:Rozeboom, H.J, Ferrari, A.R, Fraaije, M.W.
Deposit date:2016-05-30
Release date:2016-09-21
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Discovery of a Xylooligosaccharide Oxidase from Myceliophthora thermophila C1.
J.Biol.Chem., 291, 2016
5K8E
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Xylooligosaccharide oxidase from Myceliophthora thermophila C1
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Rozeboom, H.J, Ferrari, A.R, Fraaije, M.W.
Deposit date:2016-05-30
Release date:2016-09-21
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Discovery of a Xylooligosaccharide Oxidase from Myceliophthora thermophila C1.
J.Biol.Chem., 291, 2016
5L6F
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Xylooligosaccharide oxidase from Myceliophthora thermophila C1 in complex with Xylobiose
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DI(HYDROXYETHYL)ETHER, ...
Authors:Rozeboom, H.J, Ferrari, A.R, Fraaije, M.W.
Deposit date:2016-05-30
Release date:2016-09-21
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Discovery of a Xylooligosaccharide Oxidase from Myceliophthora thermophila C1.
J.Biol.Chem., 291, 2016
4X7V
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BU of 4x7v by Molmil
MycF mycinamicin III 3'-O-methyltransferase (E35Q, E139A variant) in complex with Mg, SAH and mycinamicin IV (product)
Descriptor: MAGNESIUM ION, MYCINAMICIN IV, Mycinamicin III 3''-O-methyltransferase, ...
Authors:Bernard, S.M, Smith, J.L.
Deposit date:2014-12-09
Release date:2015-03-04
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Structural Basis of Substrate Specificity and Regiochemistry in the MycF/TylF Family of Sugar O-Methyltransferases.
Acs Chem.Biol., 10, 2015
6IY9
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BU of 6iy9 by Molmil
Crystal structure of aminoglycoside 7"-phoshotransferase-Ia (APH(7")-Ia/HYG) from Streptomyces hygroscopicus complexed with hygromycin B
Descriptor: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, CITRATE ANION, HYGROMYCIN B VARIANT, ...
Authors:Takenoya, M, Shimamura, T, Yamanaka, R, Adachi, Y, Ito, S, Sasaki, Y, Nakamura, A, Yajima, S.
Deposit date:2018-12-14
Release date:2019-09-11
Last modified:2019-11-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis for the substrate recognition of aminoglycoside 7''-phosphotransferase-Ia from Streptomyces hygroscopicus.
Acta Crystallogr.,Sect.F, 75, 2019
4X7Z
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MycF mycinamicin III 3'-O-methyltransferase (E35Q, M56A, E139A variant) in complex with Mg, SAH and mycinamicin III (substrate)
Descriptor: DIMETHYL SULFOXIDE, MAGNESIUM ION, MYCINAMICIN III, ...
Authors:Bernard, S.M, Smith, J.L.
Deposit date:2014-12-09
Release date:2015-03-04
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.44 Å)
Cite:Structural Basis of Substrate Specificity and Regiochemistry in the MycF/TylF Family of Sugar O-Methyltransferases.
Acs Chem.Biol., 10, 2015
4X7W
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BU of 4x7w by Molmil
MycF mycinamicin III 3'-O-methyltransferase (E35Q, E139A variant) in complex with Mg, SAH and mycinamicin VI (MycE substrate)
Descriptor: MAGNESIUM ION, Mycinamicin III 3''-O-methyltransferase, Mycinamicin VI, ...
Authors:Bernard, S.M, Smith, J.L.
Deposit date:2014-12-09
Release date:2015-03-04
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural Basis of Substrate Specificity and Regiochemistry in the MycF/TylF Family of Sugar O-Methyltransferases.
Acs Chem.Biol., 10, 2015
3MYU
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BU of 3myu by Molmil
Mycoplasma genitalium MG289
Descriptor: 3-(4-AMINO-2-METHYL-PYRIMIDIN-5-YLMETHYL)-5-(2-HYDROXY-ETHYL)-4-METHYL-THIAZOL-3-IUM, ACETATE ION, High affinity transport system protein p37
Authors:Sippel, K.H, Boehlein, S.K, Govindasamy, L, Namiki, K, Satai, Y, Quirit, J.G, Agbandje-McKenna, M, Goodison, S, Rosser, C.J, Sankaran, B, McKenna, R.
Deposit date:2010-05-11
Release date:2010-10-20
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Insights into Mycoplasma genitalium metabolism revealed by the structure of MG289, an extracytoplasmic thiamine binding lipoprotein.
Proteins, 79, 2011
6T6Z
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BU of 6t6z by Molmil
Structure of the Bottromycin epimerase BotH in complex with a bottromycin A2 derivative
Descriptor: BotH, Bottromycin A2 derivative
Authors:Koehnke, J, Sikandar, A.
Deposit date:2019-10-20
Release date:2020-07-15
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The bottromycin epimerase BotH defines a group of atypical alpha / beta-hydrolase-fold enzymes.
Nat.Chem.Biol., 16, 2020
6T70
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BU of 6t70 by Molmil
Structure of the Bottromycin epimerase BotH in complex with Bottromycin A2 derivative
Descriptor: BotH, Bottromycin A2 derivative, CHLORIDE ION, ...
Authors:Koehnke, J, Sikandar, A.
Deposit date:2019-10-20
Release date:2020-07-15
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:The bottromycin epimerase BotH defines a group of atypical alpha / beta-hydrolase-fold enzymes.
Nat.Chem.Biol., 16, 2020
6RUT
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BU of 6rut by Molmil
Mycoplasma Genitalium Heterodimer Nap Complex (P140-P110 globular)
Descriptor: Adhesin P1, Mgp-operon protein 3
Authors:Fita, I, Aparicio, D.
Deposit date:2019-05-29
Release date:2020-06-24
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structure and mechanism of the Nap adhesion complex from the human pathogen Mycoplasma genitalium.
Nat Commun, 11, 2020
4XCB
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BU of 4xcb by Molmil
Crystal Structure of HygX from Streptomyces hygroscopicus with nickel, 2-oxoglutarate, and hygromycin B bound
Descriptor: 2-OXOGLUTARIC ACID, HYGROMYCIN B VARIANT, NICKEL (II) ION, ...
Authors:McCulloch, K.M, McCranie, E.K, Sarwar, M, Mathieu, J.L, Gitschlag, B.L, Du, Y, Bachmann, B.O, Iverson, T.M.
Deposit date:2014-12-17
Release date:2015-08-05
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Oxidative cyclizations in orthosomycin biosynthesis expand the known chemistry of an oxygenase superfamily.
Proc.Natl.Acad.Sci.USA, 112, 2015
6T6Y
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BU of 6t6y by Molmil
Structure of the Bottromycin epimerase BotH in complex with Bottromycin A2
Descriptor: BotH, Bottromycin A2
Authors:Koehnke, J, Sikandar, A.
Deposit date:2019-10-20
Release date:2020-07-15
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:The bottromycin epimerase BotH defines a group of atypical alpha / beta-hydrolase-fold enzymes.
Nat.Chem.Biol., 16, 2020
6R41
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BU of 6r41 by Molmil
Structure of P110 from Mycoplasma genitalium complexed with 3'SL
Descriptor: GLYCEROL, Mgp-operon protein 3, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose, ...
Authors:Aparicio, D, Fita, I.
Deposit date:2019-03-21
Release date:2019-05-08
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Mycoplasma genitalium adhesin P110 binds sialic-acid human receptors.
Nat Commun, 9, 2018
6R3T
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BU of 6r3t by Molmil
Structure of P110 from Mycoplasma Genitalium at 2.7A
Descriptor: Mgp-operon protein 3, PHOSPHATE ION, POTASSIUM ION
Authors:Aparicio, D, Fita, I.
Deposit date:2019-03-21
Release date:2019-04-10
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (2.73 Å)
Cite:Mycoplasma genitalium adhesin P110 binds sialic-acid human receptors.
Nat Commun, 9, 2018
6R43
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BU of 6r43 by Molmil
Structure of P110 from Mycoplasma Genitalium complexed with 6'-SL
Descriptor: Mgp-operon protein 3, N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-beta-D-glucopyranose, PHOSPHATE ION, ...
Authors:Aparicio, D, Fita, I.
Deposit date:2019-03-21
Release date:2019-04-10
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.52 Å)
Cite:Mycoplasma genitalium adhesin P110 binds sialic-acid human receptors.
Nat Commun, 9, 2018
2QEX
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BU of 2qex by Molmil
Negamycin Binds to the Wall of the Nascent Chain Exit Tunnel of the 50S Ribosomal Subunit
Descriptor: 23S ribosomal RNA, 50S ribosomal protein L10e, 50S ribosomal protein L11P, ...
Authors:Schroeder, S.J, Blaha, G.
Deposit date:2007-06-26
Release date:2008-09-30
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Negamycin binds to the wall of the nascent chain exit tunnel of the 50S ribosomal subunit.
Antimicrob.Agents Chemother., 51, 2007
6TKT
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BU of 6tkt by Molmil
Structure of the bacterial toxin phenomycin
Descriptor: Pre-phenomycin
Authors:Nielsen, J.T, Mulder, F.A.A, Toerring, T, Poulsen, T.
Deposit date:2019-11-28
Release date:2020-01-22
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Structure and Function of the Bacterial Protein Toxin Phenomycin.
Structure, 28, 2020
6E16
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BU of 6e16 by Molmil
Ternary structure of c-Myc-TBP-TAF1
Descriptor: Transcription initiation factor TFIID subunit 1,Myc proto-oncogene protein,TATA-box-binding protein
Authors:Wei, Y, Dong, A, Sunnerhagen, M, Penn, L, Tong, Y, Edwards, A.M, Arrowsmith, C.H, Structural Genomics Consortium (SGC)
Deposit date:2018-07-09
Release date:2019-10-02
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Multiple direct interactions of TBP with the MYC oncoprotein.
Nat.Struct.Mol.Biol., 26, 2019
6E24
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BU of 6e24 by Molmil
Ternary structure of c-Myc-TBP-TAF1
Descriptor: Transcription initiation factor TFIID subunit 1,Myc proto-oncogene protein,TATA-box-binding protein
Authors:Wei, Y, Dong, A, Sunnerhagen, M, Penn, L, Tong, Y, Edwards, A.M, Arrowsmith, C.H, Structural Genomics Consortium (SGC)
Deposit date:2018-07-10
Release date:2019-10-02
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (3.001 Å)
Cite:Multiple direct interactions of TBP with the MYC oncoprotein.
Nat.Struct.Mol.Biol., 26, 2019
2FF4
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BU of 2ff4 by Molmil
Mycobacterium tuberculosis EmbR in complex with low affinity phosphopeptide
Descriptor: DNA repair protein RAD9, Probable regulatory protein embR
Authors:Futterer, K, Alderwick, L.J, Besra, G.S.
Deposit date:2005-12-19
Release date:2006-01-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Molecular structure of EmbR, a response element of Ser/Thr kinase signaling in Mycobacterium tuberculosis.
Proc.Natl.Acad.Sci.Usa, 103, 2006

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