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6NDE	RHODOCETIN IN COMPLEX WITH THE INTEGRIN ALPHA2-A DOMAIN WITH PRASEDYMIUM Descriptor: AMMONIUM ION, CHLORIDE ION, Integrin alpha-2, ... Authors: Stetefeld, J, McDougall, M.D, Loewen, P.C. Deposit date: 2018-12-13 Release date: 2019-01-23 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (3.5 Å) Cite: RHODOCETIN IN COMPLEX WITH THE INTEGRIN ALPHA2-A DOMAIN WITH PRASEDYMIUM BOUND To be published
6NDH	RHODOCETIN IN COMPLEX WITH THE INTEGRIN ALPHA2-A DOMAIN AND ZINC Descriptor: AMMONIUM ION, CHLORIDE ION, Integrin alpha-2, ... Authors: Stetefeld, J, McDougall, M.D, Loewen, P.C. Deposit date: 2018-12-13 Release date: 2019-01-23 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.9 Å) Cite: RHODOCETIN IN COMPLEX WITH THE INTEGRIN ALPHA2-A DOMAIN WITH ZINC BOUND To be published
6NDB	RHODOCETIN IN COMPLEX WITH THE INTEGRIN ALPHA2-A DOMAIN AND COBALT Descriptor: AMMONIUM ION, CHLORIDE ION, COBALT (II) ION, ... Authors: Stetefeld, J, McDougall, M.D, Loewen, P.C. Deposit date: 2018-12-13 Release date: 2019-01-23 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (3.2 Å) Cite: RHODOCETIN IN COMPLEX WITH THE INTEGRIN ALPHA2-A DOMAIN AND COBALT To be published
6ND8	RHODOCETIN IN COMPLEX WITH THE INTEGRIN ALPHA2-A DOMAIN AND BARIUM Descriptor: AMMONIUM ION, BARIUM ION, CHLORIDE ION, ... Authors: Stetefeld, J, McDougall, M.D, Loewen, P.C. Deposit date: 2018-12-13 Release date: 2018-12-26 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.9 Å) Cite: RHODOCETIN IN COMPLEX WITH THE INTEGRIN ALPHA2-A DOMAIN AND BARIUM To be published
6NDD	RHODOCETIN IN COMPLEX WITH THE INTEGRIN ALPHA2-A DOMAIN WITH MANGANESE BOUND Descriptor: AMMONIUM ION, CHLORIDE ION, Integrin alpha-2, ... Authors: Stetefeld, J, McDougall, M.D, Loewen, P.C. Deposit date: 2018-12-13 Release date: 2018-12-26 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (3.05 Å) Cite: RHODOCETIN IN COMPLEX WITH THE INTEGRIN ALPHA2-A DOMAIN WITH MANGANESE BOUND To be published
1RTK	Crystal Structure Analysis of the Bb segment of Factor B complexed with 4-guanidinobenzoic acid Descriptor: 4-carbamimidamidobenzoic acid, Complement factor B Bb fragment, IODIDE ION, ... Authors: Ponnuraj, K, Xu, Y, Macon, K, Moore, D, Volanakis, J.E, Narayana, S.V. Deposit date: 2003-12-10 Release date: 2004-12-14 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structural analysis of engineered Bb fragment of complement factor B: insights into the activation mechanism of the alternative pathway C3-convertase. Mol.Cell, 14, 2004
1RRK	Crystal Structure Analysis of the Bb segment of Factor B Descriptor: COBALT (II) ION, Complement factor B, IODIDE ION, ... Authors: Ponnuraj, K, Xu, Y, Macon, K, Moore, D, Volanakis, J.E, Narayana, S.V. Deposit date: 2003-12-08 Release date: 2004-12-14 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (2 Å) Cite: Structural analysis of engineered Bb fragment of complement factor B: insights into the activation mechanism of the alternative pathway C3-convertase. Mol.Cell, 14, 2004
1RS0	Crystal Structure Analysis of the Bb segment of Factor B complexed with Di-isopropyl-phosphate (DIP) Descriptor: Complement factor B, DIISOPROPYL PHOSPHONATE, IODIDE ION, ... Authors: Ponnuraj, K, Xu, Y, Macon, K, Moore, D, Volanakis, J.E, Narayana, S.V. Deposit date: 2003-12-09 Release date: 2004-12-14 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Structural analysis of engineered Bb fragment of complement factor B: insights into the activation mechanism of the alternative pathway C3-convertase. Mol.Cell, 14, 2004
7JTN	Human Complement Factor B Inhibited by a Slow Off-Rate Modified Aptamer of 29 Bases Descriptor: Complement factor B, DNA (30-MER) Authors: Xu, X, Geisbrecht, B.V. Deposit date: 2020-08-18 Release date: 2020-12-09 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Inhibition of the Complement Alternative Pathway by Chemically Modified DNA Aptamers That Bind with Picomolar Affinity to Factor B. J Immunol., 206, 2021
7JTQ	Human Complement Factor B Inhibited by a Slow Off-Rate Modified Aptamer of 31 Bases Descriptor: Complement factor B, DNA (32-MER) Authors: Xu, X, Geisbrecht, B.V. Deposit date: 2020-08-18 Release date: 2020-12-09 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (3.5 Å) Cite: Inhibition of the Complement Alternative Pathway by Chemically Modified DNA Aptamers That Bind with Picomolar Affinity to Factor B. J Immunol., 206, 2021
1IJK	The von Willebrand Factor mutant (I546V) A1 domain-botrocetin Complex Descriptor: Botrocetin, von Willebrand factor Authors: Fukuda, K, Doggett, T.A, Bankston, L.A, Cruz, M.A, Diacovo, T.G, Liddington, R.C. Deposit date: 2001-04-26 Release date: 2002-07-10 Last modified: 2021-10-27 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Structural basis of von Willebrand factor activation by the snake toxin botrocetin. Structure, 10, 2002
8ENU	Structure of the C3bB proconvertase in complex with lufaxin Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C3 beta chain, Complement C3b alpha' chain, ... Authors: Andersen, J.F, Lei, H. Deposit date: 2022-09-30 Release date: 2023-08-09 Last modified: 2024-02-21 Method: ELECTRON MICROSCOPY (3.22 Å) Cite: A bispecific inhibitor of complement and coagulation blocks activation in complementopathy models via a novel mechanism. Blood, 141, 2023
8EOK	Structure of the C3bB proconvertase in complex with lufaxin and factor Xa Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Activated factor Xa heavy chain, Complement C3 beta chain, ... Authors: Andersen, J.F, Lei, H. Deposit date: 2022-10-03 Release date: 2023-08-30 Method: ELECTRON MICROSCOPY (3.53 Å) Cite: A bispecific inhibitor of complement and coagulation blocks activation in complementopathy models via a novel mechanism. Blood, 141, 2023

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