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PDB: 2 results

7P35
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BU of 7p35 by Molmil
Structure of the SARS-CoV-2 3CL protease in complex with rupintrivir
Descriptor: 3C-like proteinase, 4-{2-(4-FLUORO-BENZYL)-6-METHYL-5-[(5-METHYL-ISOXAZOLE-3-CARBONYL)-AMINO]-4-OXO-HEPTANOYLAMINO}-5-(2-OXO-PYRROLIDIN-3-YL)-PENTANOIC ACID ETHYL ESTER
Authors:Fabrega-Ferrer, M, Perez-Saavedra, J, Herrera-Morande, A, Coll, M.
Deposit date:2021-07-07
Release date:2021-07-21
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.256 Å)
Cite:Structure and inhibition of SARS-CoV-1 and SARS-CoV-2 main proteases by oral antiviral compound AG7404.
Antiviral Res., 208, 2022
7P2G
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BU of 7p2g by Molmil
Identification of low micromolar SARS-CoV-2 Mpro inhibitors from hits identified by in silico screens
Descriptor: (4~{R})-~{N}-(4-iodophenyl)-2-oxidanylidene-3,4-dihydro-1~{H}-quinoline-4-carboxamide, 3C-like proteinase
Authors:Rempel, S, Halazonetis, T.D.
Deposit date:2021-07-05
Release date:2022-05-04
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Non-covalent SARS-CoV-2 M pro inhibitors developed from in silico screen hits.
Sci Rep, 12, 2022

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