9HPI
 
 | | Cryo-EM structure of DDB1dB-CRBN-MRT-0031619, conformation 1 | | Descriptor: | (3~{S})-3-[3-oxidanylidene-5-[8-(phenylcarbonyl)-2,8-diazaspiro[4.5]decan-2-yl]-1~{H}-isoindol-2-yl]piperidine-2,6-dione, DNA damage-binding protein 1, Protein cereblon, ... | | Authors: | Langousis, G, Hunkeler, M, Chami, M, Quan, C, Townson, S, Bonenfant, D. | | Deposit date: | 2024-12-13 | | Release date: | 2025-12-03 | | Method: | ELECTRON MICROSCOPY (2.93 Å) | | Cite: | A degron-mimicking molecular glue drives CRBN homo-dimerization and degradation.
Nat Commun, 16, 2025
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9HPJ
 | | Cryo-EM structure of DDB1dB-CRBN-MRT-0031619, conformation 2 | | Descriptor: | (3~{S})-3-[3-oxidanylidene-5-[8-(phenylcarbonyl)-2,8-diazaspiro[4.5]decan-2-yl]-1~{H}-isoindol-2-yl]piperidine-2,6-dione, DNA damage-binding protein 1, Protein cereblon, ... | | Authors: | Langousis, G, Hunkeler, M, Chami, M, Quan, C, Townson, S, Bonenfant, D. | | Deposit date: | 2024-12-13 | | Release date: | 2025-12-03 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | A degron-mimicking molecular glue drives CRBN homo-dimerization and degradation.
Nat Commun, 16, 2025
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