9DOM
 
 | | PVTX-405: A Potent, Highly Selective, and Orally Efficacious Molecular Glue Degrader of IKZF2 for Cancer Immunotherapy | | Descriptor: | (3S)-3-(1'-benzyl-6-oxo-6,8-dihydro-2H,7H-spiro[furo[2,3-e]isoindole-3,4'-piperidin]-7-yl)piperidine-2,6-dione, Protein cereblon, ZINC ION, ... | | Authors: | Strickland, C.O, Rice, C.T. | | Deposit date: | 2024-09-19 | | Release date: | 2025-05-14 | | Method: | X-RAY DIFFRACTION (1.69 Å) | | Cite: | Development of PVTX-405 as a potent and highly selective molecular glue degrader of IKZF2 for cancer immunotherapy.
Nat Commun, 16, 2025
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