3JR4
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![BU of 3jr4 by Molmil](/molmil-images/mine/3jr4) | MutM interrogating an extrahelical G | Descriptor: | DNA (5'-D(*AP*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*C)-3'), DNA (5'-D(*TP*G*CP*GP*TP*CP*CP*AP*(GX1)P*GP*TP*CP*TP*AP*CP*C)-3'), DNA glycosylase, ... | Authors: | Qi, Y, Spong, M.C, Verdine, G.L. | Deposit date: | 2009-09-08 | Release date: | 2009-11-03 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.601 Å) | Cite: | Entrapment and structure of an extrahelical guanine attempting to enter the active site of a bacterial DNA glycosylase, MutM. J.Biol.Chem., 285, 2010
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3JR9
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3JRF
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![BU of 3jrf by Molmil](/molmil-images/mine/3jrf) | |
3JRP
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![BU of 3jrp by Molmil](/molmil-images/mine/3jrp) | SEC13 with NUP145C (AA109-179) insertion blade | Descriptor: | FUSION PROTEIN OF PROTEIN TRANSPORT PROTEIN SEC13 AND NUCLEOPORIN NUP145 | Authors: | Brohawn, S.G, Gogola, M, Schwartz, T.U. | Deposit date: | 2009-09-08 | Release date: | 2009-10-27 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Molecular architecture of the Nup84-Nup145C-Sec13 edge element in the nuclear pore complex lattice. Nat.Struct.Mol.Biol., 16, 2009
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3JSK
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![BU of 3jsk by Molmil](/molmil-images/mine/3jsk) | Thiazole synthase from Neurospora crassa | Descriptor: | ADENOSINE DIPHOSPHATE 5-(BETA-ETHYL)-4-METHYL-THIAZOLE-2-CARBOXYLIC ACID, CyPBP37 protein, FE (II) ION | Authors: | Kang, Y.N, Bale, S, Ealick, S.E. | Deposit date: | 2009-09-10 | Release date: | 2010-09-29 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structure of thiazole synthase Thi4 from Neurospora crassa to be published
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3JUA
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![BU of 3jua by Molmil](/molmil-images/mine/3jua) | |
3JUJ
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![BU of 3juj by Molmil](/molmil-images/mine/3juj) | |
3JV0
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![BU of 3jv0 by Molmil](/molmil-images/mine/3jv0) | |
3JV5
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![BU of 3jv5 by Molmil](/molmil-images/mine/3jv5) | |
3JVE
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![BU of 3jve by Molmil](/molmil-images/mine/3jve) | |
3JWI
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![BU of 3jwi by Molmil](/molmil-images/mine/3jwi) | |
3K02
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![BU of 3k02 by Molmil](/molmil-images/mine/3k02) | Crystal structures of the GacH receptor of Streptomyces glaucescens GLA.O in the unliganded form and in complex with acarbose and an acarbose homolog. Comparison with acarbose-loaded maltose binding protein of Salmonella typhimurium. | Descriptor: | 4,6-dideoxy-4-{[(1S,2R,3R,4S,5S)-2,3,4-trihydroxy-5-(hydroxymethyl)cyclohexyl]amino}-alpha-D-allopyranosyl-(1->4)-alpha-D-glucopyranosyl-(1->4)-alpha-D-glucopyranosyl-(1->4)-alpha-D-glucopyranose, Acarbose/maltose binding protein GacH, SULFATE ION | Authors: | Vahedi-Faridi, A, Licht, A, Bulut, H, Schneider, E. | Deposit date: | 2009-09-24 | Release date: | 2010-02-16 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Crystal Structures of the Solute Receptor GacH of Streptomyces glaucescens in Complex with Acarbose and an Acarbose Homolog: Comparison with the Acarbose-Loaded Maltose-Binding Protein of Salmonella typhimurium. J.Mol.Biol., 397, 2010
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3K10
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3K16
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![BU of 3k16 by Molmil](/molmil-images/mine/3k16) | Crystal Structure of BRCA1 BRCT D1840T in complex with a minimal recognition tetrapeptide with a free carboxy C-terminus | Descriptor: | Breast cancer type 1 susceptibility protein, CHLORIDE ION, NICKEL (II) ION, ... | Authors: | Campbell, S.J, Edwards, R.A, Glover, J.N. | Deposit date: | 2009-09-25 | Release date: | 2010-03-02 | Last modified: | 2021-10-13 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Comparison of the Structures and Peptide Binding Specificities of the BRCT Domains of MDC1 and BRCA1 Structure, 18, 2010
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3JPV
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![BU of 3jpv by Molmil](/molmil-images/mine/3jpv) | Crystal structure of human proto-oncogene serine threonine kinase (PIM1) in complex with a consensus peptide and a pyrrolo[2,3-a]carbazole ligand | Descriptor: | 1,10-dihydropyrrolo[2,3-a]carbazole-3-carbaldehyde, Peptide (PIMTIDE) ARKRRRHPSGPPTA, Proto-oncogene serine/threonine-protein kinase Pim-1 | Authors: | Filippakopoulos, P, Bullock, A.N, Fedorov, O, Akue-Gedu, R, Rossignol, E, Azzaro, S, Bain, J, Cohen, P, Prudhomme, M, Moreau, P, Amizon, F, von Delft, F, Arrowsmith, C.H, Weigelt, J, Edwards, A, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2009-09-04 | Release date: | 2009-10-27 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Synthesis, kinase inhibitory potencies, and in vitro antiproliferative evaluation of new pim kinase inhibitors. J.Med.Chem., 52, 2009
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3JQ1
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3JQC
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![BU of 3jqc by Molmil](/molmil-images/mine/3jqc) | Crystal structure of pteridine reductase 1 (PTR1) from Trypanosoma brucei in ternary complex with cofactor (NADP+) and inhibitor 2-amino-6-bromo-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile (JU2) | Descriptor: | 2-amino-6-bromo-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Pteridine reductase 1 | Authors: | Tulloch, L.B, Hunter, W.N. | Deposit date: | 2009-09-06 | Release date: | 2009-12-08 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structure-based design of pteridine reductase inhibitors targeting african sleeping sickness and the leishmaniases. J.Med.Chem., 53, 2010
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3K50
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3K7A
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![BU of 3k7a by Molmil](/molmil-images/mine/3k7a) | Crystal Structure of an RNA polymerase II-TFIIB complex | Descriptor: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... | Authors: | Liu, X, Bushnell, D.A, Wang, D, Calero, G, Kornberg, R.D. | Deposit date: | 2009-10-12 | Release date: | 2009-11-24 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (3.8 Å) | Cite: | Structure of an RNA polymerase II-TFIIB complex and the transcription initiation mechanism. Science, 327, 2010
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3JRD
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3JRM
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![BU of 3jrm by Molmil](/molmil-images/mine/3jrm) | |
3K8R
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![BU of 3k8r by Molmil](/molmil-images/mine/3k8r) | |
3JSU
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![BU of 3jsu by Molmil](/molmil-images/mine/3jsu) | Quadruple mutant(N51I+C59R+S108N+I164L) plasmodium falciparum dihydrofolate reductase-thymidylate synthase(PFDHFR-TS) complexed with QN254, NADPH, and dUMP | Descriptor: | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, 5-chloro-N~6~-(2,5-dimethoxybenzyl)quinazoline-2,4,6-triamine, Dihydrofolate reductase-thymidylate synthase, ... | Authors: | Chitnumsub, P, Maneeruttanarungroj, C, Kamchonwongpaisan, S, Yuthavong, Y, Diagana, T.T. | Deposit date: | 2009-09-11 | Release date: | 2010-07-28 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Preclinical evaluation of the antifolate QN254, 5-chloro- N'6'-(2,5-dimethoxy-benzyl)-quinazoline-2,4,6-triamine, as an antimalarial drug candidate Antimicrob.Agents Chemother., 54, 2010
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3K8Y
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![BU of 3k8y by Molmil](/molmil-images/mine/3k8y) | Allosteric modulation of H-Ras GTPase | Descriptor: | ACETATE ION, CALCIUM ION, GTPase HRas, ... | Authors: | Holzapfel, G, Buhrman, G, Mattos, C. | Deposit date: | 2009-10-15 | Release date: | 2010-03-02 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Allosteric modulation of Ras positions Q61 for a direct role in catalysis. Proc.Natl.Acad.Sci.USA, 107, 2010
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3JTX
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