3IEF
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3IMT
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![BU of 3imt by Molmil](/molmil-images/mine/3imt) | Transthyretin in complex with (E)-4-(4-aminostyryl)-2,6-dibromophenol | Descriptor: | 4-[(E)-2-(4-aminophenyl)ethenyl]-2,6-dibromophenol, Transthyretin | Authors: | Connelly, S, Wilson, I. | Deposit date: | 2009-08-11 | Release date: | 2010-01-12 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | A substructure combination strategy to create potent and selective transthyretin kinetic stabilizers that prevent amyloidogenesis and cytotoxicity. J.Am.Chem.Soc., 132, 2010
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3IET
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![BU of 3iet by Molmil](/molmil-images/mine/3iet) | Crystal Structure of 237mAb with antigen | Descriptor: | 2-acetamido-2-deoxy-alpha-D-galactopyranose, Immunoglobulin heavy chain (IgG2a), Immunoglobulin light chain (IgG2a), ... | Authors: | Brooks, C.L, Evans, S.V, Borisova, S.N. | Deposit date: | 2009-07-23 | Release date: | 2010-06-23 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Antibody recognition of a unique tumor-specific glycopeptide antigen. Proc.Natl.Acad.Sci.USA, 107, 2010
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3IN7
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3INU
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![BU of 3inu by Molmil](/molmil-images/mine/3inu) | Crystal structure of an unbound KZ52 neutralizing anti-Ebolavirus antibody. | Descriptor: | GLYCEROL, KZ52 antibody fragment heavy chain, KZ52 antibody fragment light chain, ... | Authors: | Lee, J.E, Fusco, M.L, Abelson, D.M, Hessell, A.J, Burton, D.R, Saphire, E.O. | Deposit date: | 2009-08-12 | Release date: | 2009-10-27 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Techniques and tactics used in determining the structure of the trimeric ebolavirus glycoprotein. Acta Crystallogr.,Sect.D, 65, 2009
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3IOK
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![BU of 3iok by Molmil](/molmil-images/mine/3iok) | 2-Aminopyrazolo[1,5-a]pyrimidines as potent and selective inhibitors of JAK2 | Descriptor: | 3-(6-{[(1S)-1-(4-fluorophenyl)ethyl]amino}pyrimidin-4-yl)pyrazolo[1,5-a]pyrimidin-2-amine, Tyrosine-protein kinase JAK2 | Authors: | Zuccola, H.J, Ledeboer, M.W, Pierce, A.C. | Deposit date: | 2009-08-14 | Release date: | 2009-11-10 | Last modified: | 2013-04-03 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | 2-Aminopyrazolo[1,5-a]pyrimidines as potent and selective inhibitors of JAK2. Bioorg.Med.Chem.Lett., 19, 2009
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3ITA
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![BU of 3ita by Molmil](/molmil-images/mine/3ita) | Crystal structure of Penicillin-Binding Protein 6 (PBP6) from E. coli in acyl-enzyme complex with ampicillin | Descriptor: | (2R,4S)-2-[(1R)-1-{[(2R)-2-amino-2-phenylacetyl]amino}-2-oxoethyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid, (2S,5R,6R)-6-{[(2R)-2-AMINO-2-PHENYLETHANOYL]AMINO}-3,3-DIMETHYL-7-OXO-4-THIA-1-AZABICYCLO[3.2.0]HEPTANE-2-CARBOXYLIC ACID, D-alanyl-D-alanine carboxypeptidase dacC, ... | Authors: | Chen, Y, Zhang, W, Shi, Q, Hesek, D, Lee, M, Mobashery, S, Shoichet, B.K. | Deposit date: | 2009-08-27 | Release date: | 2009-10-20 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structures of penicillin-binding protein 6 from Escherichia coli. J.Am.Chem.Soc., 131, 2009
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3ITQ
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![BU of 3itq by Molmil](/molmil-images/mine/3itq) | Crystal Structure of a Prolyl 4-Hydroxylase from Bacillus anthracis | Descriptor: | GLYCEROL, PHOSPHATE ION, Prolyl 4-hydroxylase, ... | Authors: | Culpepper, M.A, Scott, E.E, Limburg, J. | Deposit date: | 2009-08-28 | Release date: | 2009-12-15 | Last modified: | 2017-11-01 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Crystal structure of prolyl 4-hydroxylase from Bacillus anthracis. Biochemistry, 49, 2010
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3I71
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3I76
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![BU of 3i76 by Molmil](/molmil-images/mine/3i76) | The crystal structure of the orthorhombic form of the putative HAD-hydrolase YfnB from Bacillus subtilis bound to magnesium reveals interdomain movement | Descriptor: | CHLORIDE ION, GLYCEROL, MAGNESIUM ION, ... | Authors: | Bonanno, J.B, Dickey, M, Bain, K.T, Tang, B.K, Romero, R, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2009-07-08 | Release date: | 2009-07-21 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The crystal structure of the orthorhombic form of the putative HAD-hydrolase YfnB from Bacillus subtilis bound to magnesium reveals interdomain movement To be Published
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3IJM
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![BU of 3ijm by Molmil](/molmil-images/mine/3ijm) | The structure of a restriction endonuclease-like fold superfamily protein from Spirosoma linguale. | Descriptor: | GLYCEROL, SODIUM ION, SULFATE ION, ... | Authors: | Cuff, M.E, Tesar, C, Samano, S, Bearden, J, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2009-08-04 | Release date: | 2009-09-22 | Last modified: | 2017-11-01 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | The structure of a restriction endonuclease-like fold superfamily protein from Spirosoma linguale. TO BE PUBLISHED
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3I9I
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![BU of 3i9i by Molmil](/molmil-images/mine/3i9i) | Crystal structure of human transthyretin variant A25T - #2 | Descriptor: | TRIETHYLENE GLYCOL, Transthyretin | Authors: | Palmieri, L.C, Freire, J.B.B, Palhano, F.L, Azevedo, E.P.C, Foguel, D, Lima, L.M.T.R. | Deposit date: | 2009-07-11 | Release date: | 2011-02-23 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of human transthyretin variant A25T - #2 To be Published
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3IMK
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3INA
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![BU of 3ina by Molmil](/molmil-images/mine/3ina) | Crystal structure of heparin lyase I H151A mutant complexed with a dodecasaccharide heparin | Descriptor: | 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-3,6-di-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid, CALCIUM ION, Heparin lyase I | Authors: | Han, Y.H, Ryu, K.S, Kim, H.Y, Jeon, Y.H. | Deposit date: | 2009-08-12 | Release date: | 2009-09-29 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural snapshots of heparin depolymerization by heparin lyase I J.Biol.Chem., 284, 2009
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3IAE
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![BU of 3iae by Molmil](/molmil-images/mine/3iae) | Structure of benzaldehyde lyase A28S mutant with benzoylphosphonate | Descriptor: | 3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-2-{(S)-hydroxy[(R)-hydroxy(methoxy)phosphoryl]phenylmethyl}-5-(2-{[(R)-hydroxy(phosphonooxy)phosphoryl]oxy}ethyl)-4-methyl-1,3-thiazol-3-ium, Benzaldehyde lyase, CALCIUM ION | Authors: | Brandt, G.S, Petsko, G.A, Ringe, D, McLeish, M.J. | Deposit date: | 2009-07-13 | Release date: | 2010-03-02 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Active-site engineering of benzaldehyde lyase shows that a point mutation can confer both new reactivity and susceptibility to mechanism-based inhibition. J.Am.Chem.Soc., 132, 2010
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3INL
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![BU of 3inl by Molmil](/molmil-images/mine/3inl) | Human Mitochondrial Aldehyde Dehydrogenase Asian Variant, ALDH2*2, complexed with agonist Alda-1 | Descriptor: | 1,2-ETHANEDIOL, Aldehyde dehydrogenase, mitochondrial, ... | Authors: | Perez-Miller, S, Hurley, T.D. | Deposit date: | 2009-08-12 | Release date: | 2010-01-12 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.862 Å) | Cite: | Alda-1 is an agonist and chemical chaperone for the common human aldehyde dehydrogenase 2 variant. Nat.Struct.Mol.Biol., 17, 2010
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3IB7
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![BU of 3ib7 by Molmil](/molmil-images/mine/3ib7) | Crystal structure of full length Rv0805 | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETATE ION, ... | Authors: | Podobnik, M, Dermol, U. | Deposit date: | 2009-07-15 | Release date: | 2009-09-29 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | A mycobacterial cyclic AMP phosphodiesterase that moonlights as a modifier of cell wall permeability J.Biol.Chem., 284, 2009
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3IBK
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3IBP
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![BU of 3ibp by Molmil](/molmil-images/mine/3ibp) | The Crystal Structure of the Dimerization Domain of Escherichia coli Structural Maintenance of Chromosomes Protein MukB | Descriptor: | AMMONIUM ION, Chromosome partition protein mukB | Authors: | Li, Y, Schoeffler, A.J, Berger, J.M, Oakley, M.G. | Deposit date: | 2009-07-16 | Release date: | 2010-01-26 | Last modified: | 2017-11-01 | Method: | X-RAY DIFFRACTION (3.099 Å) | Cite: | The crystal structure of the hinge domain of the Escherichia coli structural maintenance of chromosomes protein MukB. J.Mol.Biol., 395, 2010
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3IR6
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![BU of 3ir6 by Molmil](/molmil-images/mine/3ir6) | Crystal structure of NarGHI mutant NarG-H49S | Descriptor: | (1S)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PENTANOYLOXY)METHYL]ETHYL OCTANOATE, FE3-S4 CLUSTER, GUANOSINE-5'-DIPHOSPHATE, ... | Authors: | Bertero, M.G, Rothery, R.A, Weiner, J.H, Strynadka, N.C.J. | Deposit date: | 2009-08-21 | Release date: | 2010-01-05 | Last modified: | 2021-10-13 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Protein crystallography reveals a role for the FS0 cluster of Escherichia coli nitrate reductase A (NarGHI) in enzyme maturation. J.Biol.Chem., 285, 2010
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3IDQ
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![BU of 3idq by Molmil](/molmil-images/mine/3idq) | Crystal structure of S. cerevisiae Get3 at 3.7 Angstrom resolution | Descriptor: | ATPase GET3, NICKEL (II) ION, ZINC ION | Authors: | Suloway, C.J.M, Chartron, J.W, Zaslaver, M, Clemons Jr, W.M. | Deposit date: | 2009-07-21 | Release date: | 2009-08-25 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (3.701 Å) | Cite: | Model for eukaryotic tail-anchored protein binding based on the structure of Get3 Proc.Natl.Acad.Sci.USA, 106, 2009
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3ISG
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![BU of 3isg by Molmil](/molmil-images/mine/3isg) | Structure of the class D beta-lactamase OXA-1 in complex with doripenem | Descriptor: | (2S,3R,4S)-2-[(2S,3R)-3-hydroxy-1-oxobutan-2-yl]-3-methyl-4-({(3S,5S)-5-[(sulfamoylamino)methyl]pyrrolidin-3-yl}sulfanyl)-3,4-dihydro-2H-pyrrole-5-carboxylic acid, (4S)-2-METHYL-2,4-PENTANEDIOL, Beta-lactamase OXA-1 | Authors: | Powers, R.A. | Deposit date: | 2009-08-25 | Release date: | 2009-12-01 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | The 1.4 A crystal structure of the class D beta-lactamase OXA-1 complexed with doripenem. Biochemistry, 48, 2009
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3IE1
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![BU of 3ie1 by Molmil](/molmil-images/mine/3ie1) | Crystal structure of H380A mutant TTHA0252 from Thermus thermophilus HB8 complexed with RNA | Descriptor: | CITRATE ANION, RNA (5'-R(P*UP*UP*UP*U)-3'), Ribonuclease TTHA0252, ... | Authors: | Ishikawa, H, Nakagawa, N, Kuramitsu, S, Yokoyama, S, Masui, R, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2009-07-22 | Release date: | 2009-08-04 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Crystal structure of H380A mutant TTHA0252 from Thermus thermophilus HB8 complexed with RNA To be Published
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3IT1
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![BU of 3it1 by Molmil](/molmil-images/mine/3it1) | Crystal Structure Francisella tularensis histidine acid phosphatase complexed with L(+)-tartrate | Descriptor: | 2-(2-METHOXYETHOXY)ETHANOL, ACETATE ION, Acid phosphatase, ... | Authors: | Singh, H, Felts, R.L, Reilly, T.J, Tanner, J.J. | Deposit date: | 2009-08-27 | Release date: | 2009-11-10 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.691 Å) | Cite: | Crystal Structures of the histidine acid phosphatase from Francisella tularensis provide insight into substrate recognition. J.Mol.Biol., 394, 2009
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3IU5
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![BU of 3iu5 by Molmil](/molmil-images/mine/3iu5) | Crystal structure of the first bromodomain of human poly-bromodomain containing protein 1 (PB1) | Descriptor: | Protein polybromo-1 | Authors: | Filippakopoulos, P, Picaud, S, Keates, T, Ugochukwu, E, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2009-08-30 | Release date: | 2009-09-22 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.63 Å) | Cite: | Histone recognition and large-scale structural analysis of the human bromodomain family. Cell(Cambridge,Mass.), 149, 2012
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