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2I1W
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Crystal structure of NAD kinase 1 from Listeria monocytogenes
Descriptor: IODIDE ION, Probable inorganic polyphosphate/ATP-NAD kinase 1
Authors:Poncet-Montange, G, Assairi, L, Arold, S, Pochet, S, Labesse, G.
Deposit date:2006-08-15
Release date:2007-08-07
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.34 Å)
Cite:NAD kinases use substrate-assisted catalysis for specific recognition of NAD.
J.Biol.Chem., 282, 2007
2I4P
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BU of 2i4p by Molmil
Crystal structure of the complex between PPARgamma and the partial agonist LT127 (ureidofibrate derivative). Structure obtained from crystals of the apo-form soaked for 30 days.
Descriptor: (2S)-2-(4-{2-[1,3-BENZOXAZOL-2-YL(HEPTYL)AMINO]ETHYL}PHENOXY)-2-METHYLBUTANOIC ACID, Peroxisome proliferator-activated receptor gamma
Authors:Pochetti, G, Mazza, F.
Deposit date:2006-08-22
Release date:2007-04-17
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Insights into the mechanism of partial agonism: crystal structures of the peroxisome proliferator-activated receptor gamma ligand-binding domain in the complex with two enantiomeric ligands.
J.Biol.Chem., 282, 2007
2I3Z
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BU of 2i3z by Molmil
rat DPP-IV with xanthine mimetic inhibitor #7
Descriptor: 2-[(3S)-3-AMINOPIPERIDIN-1-YL]-1-(2-CYANOBENZYL)-5-METHYL-4,6-DIOXO-3,4,5,6-TETRAHYDROPYRROLO[3,4-D]IMIDAZOL-1-IUM, Dipeptidyl peptidase 4 (Dipeptidyl peptidase IV) (DPP IV)
Authors:Kurukulasuriya, R, Rohde, J.J, Szczepankiewicz, B.G, Basha, F, Lai, C, Winn, M, Stewart, K.D, Longenecker, K.L, Lubben, T.W, Ballaron, S.J, Sham, H.L, VonGeldern, T.W.
Deposit date:2006-08-21
Release date:2006-12-12
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Xanthine mimetics as potent dipeptidyl peptidase IV inhibitors.
Bioorg.Med.Chem.Lett., 16, 2006
2I4J
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BU of 2i4j by Molmil
Crystal structure of the complex between PPARgamma and the agonist LT160 (ureidofibrate derivative)
Descriptor: (2R)-2-(4-{2-[1,3-BENZOXAZOL-2-YL(HEPTYL)AMINO]ETHYL}PHENOXY)-2-METHYLBUTANOIC ACID, Peroxisome proliferator-activated receptor gamma
Authors:Pochetti, G, Mazza, F.
Deposit date:2006-08-22
Release date:2007-04-17
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Insights into the mechanism of partial agonism: crystal structures of the peroxisome proliferator-activated receptor gamma ligand-binding domain in the complex with two enantiomeric ligands
J.Biol.Chem., 282, 2007
2I52
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BU of 2i52 by Molmil
Crystal structure of protein PTO0218 from Picrophilus torridus, Pfam DUF372
Descriptor: CALCIUM ION, CHLORIDE ION, GLYCEROL, ...
Authors:Ramagopal, U.A, Gilmore, J, Toro, R, Bain, K.T, McKenzie, C, Reyes, C, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2006-08-23
Release date:2006-09-12
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:Structure of hypothetical protein PTO0218 from Picrophilus torridus
To be Published
2I5M
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BU of 2i5m by Molmil
Crystal structure of Bacillus subtilis cold shock protein CspB variant A46K S48R
Descriptor: Cold shock protein cspB, MAGNESIUM ION
Authors:Max, K.E.A, Heinemann, U.
Deposit date:2006-08-25
Release date:2007-05-22
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Optimized variants of the cold shock protein from in vitro selection: structural basis of their high thermostability.
J.Mol.Biol., 369, 2007
2I7D
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BU of 2i7d by Molmil
Structure of Human cytosolic deoxyribonucleotidase in complex with deoxyuridine, AlF4 and Mg2+
Descriptor: 2'-DEOXYURIDINE, 5'(3')-deoxyribonucleotidase, cytosolic type, ...
Authors:Rinaldo-Matthis, A, Wallden, K, Nordlund, P.
Deposit date:2006-08-30
Release date:2007-10-30
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Structures of Human and Murine cytosolic deoxyribonucleotidase: Insights into substrate specificity and catalysis
To be Published
2I89
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Structure of septuple mutant of Rat Outer Mitochondrial Membrane Cytochrome B5
Descriptor: Cytochrome b5 type B, MAGNESIUM ION, PROTOPORPHYRIN IX CONTAINING FE
Authors:Terzyan, S, Zhang, X.C, Benson, D.R, Wang, L, Sun, N.
Deposit date:2006-09-01
Release date:2006-10-31
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A histidine/tryptophan pi-stacking interaction stabilizes the heme-independent folding core of microsomal apocytochrome b5 relative to that of mitochondrial apocytochrome b5.
Biochemistry, 45, 2006
2HZG
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Crystal structure of predicted Mandelate racemase from Rhodobacter sphaeroides
Descriptor: GLYCEROL, Mandelate racemase/muconate lactonizing enzyme/Enolase superfamily, SODIUM ION
Authors:Ramagopal, U.A, Toro, R, Almo, S.C, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2006-08-08
Release date:2006-08-29
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:Crystal structure of predicted Mandelate racemase from Rhodobacter sphaeroides
To be Published
2I2Q
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BU of 2i2q by Molmil
Fission Yeast cofilin
Descriptor: 1,2-ETHANEDIOL, Cofilin, LAURYL DIMETHYLAMINE-N-OXIDE, ...
Authors:Andrianantoandro, E, Pollard, T.D.
Deposit date:2006-08-16
Release date:2006-10-17
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Mechanism of Actin Filament Turnover by Severing and Nucleation at Different Concentrations of ADF/Cofilin.
Mol.Cell, 24, 2006
2GL2
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Crystal structure of the tetra mutant (T66G,R67G,F68G,Y69G) of bacterial adhesin FadA
Descriptor: adhesion A
Authors:Nithianantham, S, Xu, M, Wu, N, Shoham, M, Han, Y.W.
Deposit date:2006-04-04
Release date:2007-04-10
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystallization and preliminary X-ray data of the FadA adhesin from Fusobacterium nucleatum.
Acta Crystallogr.,Sect.F, 62, 2006
2GP0
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BU of 2gp0 by Molmil
HePTP Catalytic Domain (residues 44-339), S225D mutant
Descriptor: GLYCEROL, PHOSPHATE ION, Tyrosine-protein phosphatase non-receptor type 7
Authors:Page, R.
Deposit date:2006-04-15
Release date:2006-05-09
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:HePTP Catalytic Domain (residues 44-339), S225D mutant
To be Published
2GPH
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BU of 2gph by Molmil
Docking motif interactions in the MAP kinase ERK2
Descriptor: Mitogen-activated protein kinase 1, Tyrosine-protein phosphatase non-receptor type 7
Authors:Zhou, T, Sun, L, Humphreys, J, Goldsmith, E.J.
Deposit date:2006-04-17
Release date:2006-07-04
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Docking Interactions Induce Exposure of Activation Loop in the MAP Kinase ERK2.
Structure, 14, 2006
2GPY
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BU of 2gpy by Molmil
Crystal structure of putative O-methyltransferase from Bacillus halodurans
Descriptor: MAGNESIUM ION, O-methyltransferase, ZINC ION
Authors:Ramagopal, U.A, Patskovsky, Y.V, Almo, S.C, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2006-04-18
Release date:2006-06-06
Last modified:2021-02-03
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of putative O-methyltransferase from Bacillus halodurans
To be Published
2GRK
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BU of 2grk by Molmil
Crystal structure of ectromelia virus EVM1 chemokine binding protein
Descriptor: EVM001
Authors:Arnold, P.L, Fremont, D.H.
Deposit date:2006-04-24
Release date:2006-05-09
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural determinants of chemokine binding by an ectromelia virus-encoded decoy receptor.
J.Virol., 80, 2006
2GRR
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BU of 2grr by Molmil
Crystal Structure of human RanGAP1-Ubc9-D127S
Descriptor: Ran GTPase-activating protein 1, Ubiquitin-conjugating enzyme E2 I
Authors:Yunus, A.A, Lima, C.D.
Deposit date:2006-04-24
Release date:2006-05-30
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Lysine activation and functional analysis of E2-mediated conjugation in the SUMO pathway.
Nat.Struct.Mol.Biol., 13, 2006
2GPU
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BU of 2gpu by Molmil
Estrogen Related Receptor-gamma ligand binding domain complexed with 4-hydroxy-tamoxifen
Descriptor: 4-HYDROXYTAMOXIFEN, Estrogen-related receptor gamma
Authors:Wang, L, Zuercher, W.J, Consler, T.G, Lambert, M.H, Miller, A.B, Osband-Miller, L.A, McKee, D.D, Willson, T.M, Nolte, R.T.
Deposit date:2006-04-18
Release date:2006-09-26
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:X-ray crystal structures of the estrogen-related receptor-gamma ligand binding domain in three functional states reveal the molecular basis of small molecule regulation.
J.Biol.Chem., 281, 2006
2H0J
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BU of 2h0j by Molmil
Crystal structure of PucM in the presence of 5,6-diaminouracil
Descriptor: 5,6-DIAMINOPYRIMIDINE-2,4(1H,3H)-DIONE, Transthyretin-like protein pucM
Authors:Rhee, S.
Deposit date:2006-05-15
Release date:2006-06-27
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural and functional analysis of PucM, a hydrolase in the ureide pathway and a member of the transthyretin-related protein family.
Proc.Natl.Acad.Sci.Usa, 103, 2006
2GWM
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BU of 2gwm by Molmil
Crystal structure of the Salmonella SpvB ATR Domain
Descriptor: 65 kDa virulence protein, SULFATE ION
Authors:Stebbins, C.E, Margarit, S.M.
Deposit date:2006-05-04
Release date:2006-08-29
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:A steric antagonism of actin polymerization by a salmonella virulence protein.
Structure, 14, 2006
2GJ3
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BU of 2gj3 by Molmil
Crystal structure of the FAD-containing PAS domain of the protein NifL from Azotobacter vinelandii.
Descriptor: ETHANOL, FLAVIN-ADENINE DINUCLEOTIDE, Nitrogen fixation regulatory protein, ...
Authors:Key, J, Hefti, M, Purcell, E, Moffat, K.
Deposit date:2006-03-30
Release date:2007-03-06
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.04 Å)
Cite:Structure of the redox sensor domain of Azotobacter vinelandii NifL at atomic resolution: signaling, dimerization, and mechanism.
Biochemistry, 46, 2007
2GJG
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CRYSTAL STRUCTURE OF A PILZ-CONTAINING PROTEIN (PP4397) FROM PSEUDOMONAS PUTIDA KT2440 AT 2.25 A RESOLUTION
Descriptor: 1,2-ETHANEDIOL, hypothetical protein PP4397
Authors:Joint Center for Structural Genomics (JCSG)
Deposit date:2006-03-30
Release date:2006-04-25
Last modified:2023-01-25
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Crystal structure of hypothetical protein (NP_746511.1) from Pseudomonas putida KT2440 at 2.25 A resolution
To be published
2GJ8
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BU of 2gj8 by Molmil
Structure of the MnmE G-domain in complex with GDP*AlF4-, Mg2+ and K+
Descriptor: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, POTASSIUM ION, ...
Authors:Scrima, A, Wittinghofer, A.
Deposit date:2006-03-30
Release date:2006-07-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Dimerisation-dependent GTPase reaction of MnmE: how potassium acts as GTPase-activating element.
Embo J., 25, 2006
2GKO
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BU of 2gko by Molmil
S41 Psychrophilic Protease
Descriptor: CALCIUM ION, SODIUM ION, microbial serine proteinases; subtilisin, ...
Authors:Walter, R.L, Mekel, M.J, Grayling, R.A, Arnold, F.H, Wintrode, P.L, Almog, O.
Deposit date:2006-04-03
Release date:2007-05-01
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:The crystal structures of the psychrophilic subtilisin S41 and the mesophilic subtilisin Sph reveal the same calcium-loaded state.
Proteins, 74, 2009
2GLX
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Crystal Structure Analysis of bacterial 1,5-AF Reductase
Descriptor: 1,5-anhydro-D-fructose reductase, ACETATE ION, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Dambe, T.R, Scheidig, A.J.
Deposit date:2006-04-05
Release date:2006-08-29
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal Structure of NADP(H)-Dependent 1,5-Anhydro-d-fructose Reductase from Sinorhizobium morelense at 2.2 A Resolution: Construction of a NADH-Accepting Mutant and Its Application in Rare Sugar Synthesis
Biochemistry, 45, 2006
2GOO
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Ternary Complex of BMP-2 bound to BMPR-Ia-ECD and ActRII-ECD
Descriptor: 2-acetamido-2-deoxy-alpha-D-glucopyranose, Activin receptor type 2A, Bone morphogenetic protein 2, ...
Authors:Allendorph, G.P, Choe, S.
Deposit date:2006-04-13
Release date:2006-05-09
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of the ternary signaling complex of a TGF-beta superfamily member.
Proc.Natl.Acad.Sci.Usa, 103, 2006

225399

數據於2024-09-25公開中

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