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5AKV
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BU of 5akv by Molmil
Transthyretin binding heterogeneity and anti-amyloidogenic activity of natural polyphenols and their metabolites: genistein-7-O- glucuronide
Descriptor: Genistein-7-O-glucuronide, TRANSTHYRETIN
Authors:Florio, P, Foll, C, Cianci, M, Del Rio, D, Zanotti, G, Berni, R.
Deposit date:2015-03-05
Release date:2015-10-21
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.52 Å)
Cite:Transthyretin Binding Heterogeneity and Anti-Amyloidogenic Activity of Natural Polyphenols and Their Metabolites
J.Biol.Chem., 290, 2015
6ZUS
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BU of 6zus by Molmil
Crystal structure of the effector Ecp11-1 from Fulvia fulva
Descriptor: DI(HYDROXYETHYL)ETHER, Extracellular protein 11-1, GLYCEROL, ...
Authors:Lazar, N, Mesarich, C, Petit-Houdenot, Y, Talbi, N, Li de la Sierra-Gallay, I, Zelie, E, Blondeau, K, Gracy, J, Ollivier, B, van de Wouw, A, Balesdent, M.H, Idnurm, A, van Tilbeurgh, H, Fudal, I.
Deposit date:2020-07-23
Release date:2021-08-04
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:A new family of structurally conserved fungal effectors displays epistatic interactions with plant resistance proteins.
Plos Pathog., 18, 2022
6ZUQ
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BU of 6zuq by Molmil
Crystal structure of the effector Ecp11-1 from Fulvia fulva
Descriptor: Extracellular protein 11-1, GLYCEROL, ZINC ION
Authors:Lazar, N, Mesarich, C, Petit-Houdenot, Y, Talbi, N, Li de la Sierra-Gallay, I, Zelie, E, Blondeau, K, Gracy, J, Ollivier, B, van de Wouw, A, Balesdent, M.H, Idnurm, A, van Tilbeurgh, H, Fudal, I.
Deposit date:2020-07-23
Release date:2021-08-04
Last modified:2022-07-27
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:A new family of structurally conserved fungal effectors displays epistatic interactions with plant resistance proteins.
Plos Pathog., 18, 2022
7AD5
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BU of 7ad5 by Molmil
Crystal structure of the effector AvrLm5-9 from Leptosphaeria maculans
Descriptor: ACETATE ION, Avirulence protein LmJ1, GLYCEROL, ...
Authors:Lazar, N, Mesarich, C, Petit-Houdenot, Y, Talbi, N, Li de la Sierra-Gallay, I, Zelie, E, Blondeau, K, Gracy, J, Ollivier, B, van de Wouw, A, Balesdent, M.H, Idnurm, A, van Tilbeurgh, H, Fudal, I.
Deposit date:2020-09-14
Release date:2021-10-06
Last modified:2022-07-27
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:A new family of structurally conserved fungal effectors displays epistatic interactions with plant resistance proteins.
Plos Pathog., 18, 2022
3DJS
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BU of 3djs by Molmil
Crystal structure of transthyretin variant L58H at acidic pH
Descriptor: Transthyretin
Authors:Cendron, L, Zanotti, G, Folli, C, Berni, R.
Deposit date:2008-06-24
Release date:2009-07-14
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Amyloidogenic potential of transthyretin variants: insights from structural and computational analyses.
J.Biol.Chem., 284, 2009
3DJZ
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BU of 3djz by Molmil
Crystal structure of transthyretin variant L55P at neutral pH
Descriptor: Transthyretin
Authors:Cendron, L, Zanotti, G, Folli, C, Berni, R.
Deposit date:2008-06-24
Release date:2009-07-14
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:Amyloidogenic potential of transthyretin variants: insights from structural and computational analyses.
J.Biol.Chem., 284, 2009
4P5K
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BU of 4p5k by Molmil
Structural Basis of Chronic Beryllium Disease: Bridging the Gap Between Allergy and Autoimmunity
Descriptor: HLA class II histocompatibility antigen, DP alpha 1 chain, RAS peptide,HLA class II histocompatibility antigen, ...
Authors:Clayton, G.M, Wang, Y, Crawford, F, Novikov, A, Wimberly, B.T, Kieft, J.S, Falta, M.T, Bowerman, N.A, Marrack, P, Fontenot, A.P, Dai, S, Kappler, J.W.
Deposit date:2014-03-17
Release date:2015-01-21
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:Structural basis of chronic beryllium disease: linking allergic hypersensitivity and autoimmunity.
Cell, 158, 2014
7SZZ
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BU of 7szz by Molmil
Structure of the smaller diameter PSMalpha3 nanotubes
Descriptor: Phenol-soluble modulin PSM-alpha-3
Authors:Beltran, L.C, Kreutzberger, M.A, Wang, S, Egelman, E.H, Conticello, V.P.
Deposit date:2021-11-29
Release date:2022-05-18
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Phenol-soluble modulins PSM alpha 3 and PSM beta 2 form nanotubes that are cross-alpha amyloids.
Proc.Natl.Acad.Sci.USA, 119, 2022
7T8U
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BU of 7t8u by Molmil
Structure of PSMbeta2 nanotubes
Descriptor: Antibacterial protein
Authors:Kreutzberger, M.A, Wang, S, Egelman, E.H, Conicello, V.P.
Deposit date:2021-12-17
Release date:2022-05-18
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Phenol-soluble modulins PSM alpha 3 and PSM beta 2 form nanotubes that are cross-alpha amyloids.
Proc.Natl.Acad.Sci.USA, 119, 2022
7T0X
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BU of 7t0x by Molmil
Structure of the larger diameter PSMalpha3 nanotube
Descriptor: Phenol-soluble modulin PSM-alpha-3
Authors:Kreutzberger, M.A, Wang, S, Beltran, L.C, Egelman, E.H, Conticello, V.P.
Deposit date:2021-11-30
Release date:2022-05-18
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Phenol-soluble modulins PSM alpha 3 and PSM beta 2 form nanotubes that are cross-alpha amyloids.
Proc.Natl.Acad.Sci.USA, 119, 2022
6PX7
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BU of 6px7 by Molmil
Dg12a in Weaponisation 'on the fly': Convergent recruitment of knottin and defensin scaffolds as neurotoxins in the venom of assassin fly Dolopus genitalis (Diptera: Asilidae)
Descriptor: Venom polypeptide
Authors:Agwa, A.J, Schroeder, C.
Deposit date:2019-07-25
Release date:2020-01-22
Last modified:2020-02-05
Method:SOLUTION NMR
Cite:Weaponisation 'on the fly': Convergent recruitment of knottin and defensin peptide scaffolds into the venom of predatory assassin flies.
Insect Biochem.Mol.Biol., 118, 2019
2RGK
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BU of 2rgk by Molmil
Functional annotation of Escherichia coli yihS-encoded protein
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Uncharacterized sugar isomerase yihS
Authors:Itoh, T, Mikami, B, Hashimoto, W, Murata, K.
Deposit date:2007-10-03
Release date:2008-08-26
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of YihS in complex with D-mannose: structural annotation of Escherichia coli and Salmonella enterica yihS-encoded proteins to an aldose-ketose isomerase
J.Mol.Biol., 377, 2008
6PX8
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BU of 6px8 by Molmil
Dg3b in Weaponisation 'on the fly': Convergent recruitment of knottin and defensin scaffolds as neurotoxins in the venom of assassin fly Dolopus genitalis (Diptera: Asilidae)
Descriptor: Venom polypeptide
Authors:Agwa, A.J, Schroeder, C.
Deposit date:2019-07-25
Release date:2020-01-22
Last modified:2020-02-05
Method:SOLUTION NMR
Cite:Weaponisation 'on the fly': Convergent recruitment of knottin and defensin peptide scaffolds into the venom of predatory assassin flies.
Insect Biochem.Mol.Biol., 118, 2019
4B9B
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BU of 4b9b by Molmil
The structure of the omega aminotransferase from Pseudomonas aeruginosa
Descriptor: BETA-ALANINE-PYRUVATE TRANSAMINASE, CALCIUM ION, CHLORIDE ION, ...
Authors:Sayer, C, Isupov, M.N, Westlake, A, Littlechild, J.A.
Deposit date:2012-09-03
Release date:2013-03-27
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:Structural Studies with Pseudomonas and Chromobacterium [Omega]-Aminotransferases Provide Insights Into Their Differing Substrate Specificity.
Acta Crystallogr.,Sect.D, 69, 2013
5VEH
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BU of 5veh by Molmil
Re-refinement OF THE PDB STRUCTURE 1yiz of Aedes aegypti kynurenine aminotransferase
Descriptor: BROMIDE ION, GLYCEROL, Kynurenine aminotransferase
Authors:Wlodawer, A, Dauter, Z, Minor, W, Stanfield, R, Porebski, P, Jaskolski, M, Pozharski, E, Weichenberger, C.X, Rupp, B.
Deposit date:2017-04-04
Release date:2017-11-29
Last modified:2022-04-13
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Detect, correct, retract: How to manage incorrect structural models.
FEBS J., 285, 2018
6DQP
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BU of 6dqp by Molmil
Crystal structure of SsuE FMN reductase Delta118 mutant in apo form
Descriptor: FMN reductase (NADPH), GLYCEROL
Authors:McFarlane, J.S, Ellis, H.R, Lamb, A.L.
Deposit date:2018-06-11
Release date:2019-01-09
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.546 Å)
Cite:Not as easy as pi : An insertional residue does not explain the pi-helix gain-of-function in two-component FMN reductases.
Protein Sci., 28, 2019
6DQI
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BU of 6dqi by Molmil
Crystal structure of SsuE FMN reductase Y118A mutant in apo form.
Descriptor: FMN reductase (NADPH), SULFATE ION
Authors:McFarlane, J.S, Ellis, H.R, Lamb, A.L.
Deposit date:2018-06-11
Release date:2019-01-09
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Not as easy as pi : An insertional residue does not explain the pi-helix gain-of-function in two-component FMN reductases.
Protein Sci., 28, 2019
6DQO
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BU of 6dqo by Molmil
Crystal structure of SsuE FMN reductase Y118A mutant in FMN bound form.
Descriptor: FLAVIN MONONUCLEOTIDE, FMN reductase (NADPH), GLYCEROL
Authors:McFarlane, J.S, Ellis, H.R, Lamb, A.L.
Deposit date:2018-06-11
Release date:2019-01-09
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.705 Å)
Cite:Not as easy as pi : An insertional residue does not explain the pi-helix gain-of-function in two-component FMN reductases.
Protein Sci., 28, 2019
4BA5
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BU of 4ba5 by Molmil
Crystal structure of omega-transaminase from Chromobacterium violaceum
Descriptor: 3-[O-PHOSPHONOPYRIDOXYL]--AMINO-BENZOIC ACID, AMINOTRANSFERASE, SULFATE ION
Authors:Sayer, C, Isupov, M.N, Littlechild, J.A.
Deposit date:2012-09-11
Release date:2013-03-27
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Structural Studies with Pseudomonas and Chromobacterium [Omega]-Aminotransferases Provide Insights Into Their Differing Substrate Specificity.
Acta Crystallogr.,Sect.D, 69, 2013
4B98
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BU of 4b98 by Molmil
The structure of the omega aminotransferase from Pseudomonas aeruginosa
Descriptor: 3-[O-PHOSPHONOPYRIDOXYL]--AMINO-BENZOIC ACID, BETA-ALANINE--PYRUVATE TRANSAMINASE, CALCIUM ION, ...
Authors:Sayer, C, Isupov, M.N, Westlake, A, Littlechild, J.A.
Deposit date:2012-09-03
Release date:2013-03-27
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structural Studies with Pseudomonas and Chromobacterium [Omega]-Aminotransferases Provide Insights Into Their Differing Substrate Specificity.
Acta Crystallogr.,Sect.D, 69, 2013
8AZ8
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BU of 8az8 by Molmil
SARS-CoV-2 non-structural protein-1 (nsp1) in complex with 2-(benzylamino)ethan-1-ol
Descriptor: 2-[(phenylmethyl)amino]ethanol, Host translation inhibitor nsp1
Authors:Ma, S, Damfo, S, Pinotsis, N, Bowler, M.W, Kozielski, F.
Deposit date:2022-09-05
Release date:2022-11-23
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.18 Å)
Cite:Two Ligand-Binding Sites on SARS-CoV-2 Non-Structural Protein 1 Revealed by Fragment-Based X-ray Screening.
Int J Mol Sci, 23, 2022
4AO4
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BU of 4ao4 by Molmil
Structural Determinants of the beta-Selectivity of a Bacterial Aminotransferase
Descriptor: (3R)-3-[({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)AMINO]-5-METHYLHEXANOIC ACID, 1,2-ETHANEDIOL, Beta-transaminase
Authors:Wybenga, G.G, Crismaru, C.G, Janssen, D.B, Dijkstra, B.W.
Deposit date:2012-03-23
Release date:2012-06-06
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural determinants of the beta-selectivity of a bacterial aminotransferase.
J. Biol. Chem., 287, 2012
8ORS
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BU of 8ors by Molmil
Knockout of GMC-oxidoreductase genes reveals that functional redundancy preserves mimivirus essential functions
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, Putative GMC-type oxidoreductase
Authors:Alempic, J.M, Bisio, H, Villalta, A, Santini, S, Lartigue, A, Schmitt, A, Bugnot, C, Notaro, A, Belmudes, L, Adrait, A, Poirot, O, Ptchelkine, D, De Castro, C, Coute, Y, Abergel, C.
Deposit date:2023-04-17
Release date:2024-04-17
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Functional redundancy revealed by the deletion of the mimivirus GMC-oxidoreductase genes.
Microlife, 5, 2024
8ORH
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BU of 8orh by Molmil
Knockout of GMC-oxidoreductase genes reveals that functional redundancy preserves mimivirus essential functions
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, Putative GMC-type oxidoreductase
Authors:Alempic, J.M, Bisio, H, Villalta, A, Santini, S, Lartigue, A, Schmitt, A, Bugnot, C, Notaro, A, Belmudes, L, Adrait, A, Poirot, O, Ptchelkine, D, De Castro, C, Coute, Y, Abergel, C.
Deposit date:2023-04-14
Release date:2024-04-17
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Functional redundancy revealed by the deletion of the mimivirus GMC-oxidoreductase genes.
Microlife, 5, 2024
4C6Y
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BU of 4c6y by Molmil
Ancestral PNCA (last common ancestors of Gram-positive and Gram- negative bacteria) beta-lactamase class A
Descriptor: ACETATE ION, BETA-LACTAMASE, CHLORIDE ION, ...
Authors:Gavira, J.A, Risso, V.A, Sanchez-Ruiz, J.M.
Deposit date:2013-09-19
Release date:2014-04-16
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.799 Å)
Cite:Phenotypic Comparisons of Consensus Variants Versus Laboratory Resurrections of Precambrian Proteins.
Proteins, 82, 2014

225399

數據於2024-09-25公開中

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