6P5I
 
 | | Structure of a mammalian 80S ribosome in complex with the Israeli Acute Paralysis Virus IRES (Class 1) | | Descriptor: | 18S rRNA, 28S rRNA, 5.8S rRNA, ... | | Authors: | Acosta-Reyes, F.J, Neupane, R, Frank, J, Fernandez, I.S. | | Deposit date: | 2019-05-30 | | Release date: | 2019-09-18 | | Last modified: | 2020-02-26 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | The Israeli acute paralysis virus IRES captures host ribosomes by mimicking a ribosomal state with hybrid tRNAs.
Embo J., 38, 2019
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4ZS8
 | | Crystal structure of ligand-free, full length DasR | | Descriptor: | 1,2-ETHANEDIOL, HTH-type transcriptional repressor DasR | | Authors: | Fillenberg, S.B, Muller, Y.A. | | Deposit date: | 2015-05-13 | | Release date: | 2016-06-08 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Crystal Structures of the Global Regulator DasR from Streptomyces coelicolor: Implications for the Allosteric Regulation of GntR/HutC Repressors.
Plos One, 11, 2016
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2BEM
 | | Crystal structure of the Serratia marcescens chitin-binding protein CBP21 | | Descriptor: | 1,2-ETHANEDIOL, CBP21, SODIUM ION, ... | | Authors: | Vaaje-Kolstad, G, Houston, D.R, Eijsink, V.G.H, van Aalten, D.M.F. | | Deposit date: | 2004-11-26 | | Release date: | 2004-12-08 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | Crystal Structure and Binding Properties of the Serratia Marcescens Chitin-Binding Protein Cbp21
J.Biol.Chem., 280, 2005
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5NUS
 | | Structure of a minimal complex between p44 and p34 from Chaetomium thermophilum | | Descriptor: | ZINC ION, p34, p44 | | Authors: | Koelmel, W, Schoenwetter, E, Kuper, J, Schmitt, D.R, Kisker, C. | | Deposit date: | 2017-05-02 | | Release date: | 2017-10-18 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | The intricate network between the p34 and p44 subunits is central to the activity of the transcription/DNA repair factor TFIIH.
Nucleic Acids Res., 45, 2017
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4ZVV
 | | Lactate dehydrogenase A in complex with a trisubstituted piperidine-2,4-dione inhibitor GNE-140 | | Descriptor: | (2~{R})-5-(2-chlorophenyl)sulfanyl-2-(4-morpholin-4-ylphenyl)-4-oxidanyl-2-thiophen-3-yl-1,3-dihydropyridin-6-one, L-lactate dehydrogenase A chain, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | | Authors: | Li, Y, Chen, Z, Eigenbrot, C. | | Deposit date: | 2015-05-18 | | Release date: | 2016-05-18 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Metabolic plasticity underpins innate and acquired resistance to LDHA inhibition.
Nat.Chem.Biol., 12, 2016
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2BH0
 | | Crystal structure of a SeMet derivative of EXPA from Bacillus subtilis at 2.5 angstrom | | Descriptor: | YOAJ | | Authors: | Petrella, S, Herman, R, Sauvage, E, Filee, P, Joris, B, Charlier, P. | | Deposit date: | 2005-01-06 | | Release date: | 2006-06-28 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystal Structure and Activity of Bacillus Subtilis Yoaj (Exlx1), a Bacterial Expansin that Promotes Root Colonization.
Proc.Natl.Acad.Sci.USA, 105, 2008
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5NV5
 | | Enterococcus faecalis FIC protein | | Descriptor: | Fic family protein | | Authors: | Veyron, S, Cherfils, J. | | Deposit date: | 2017-05-03 | | Release date: | 2018-05-30 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | A Ca2+-regulated deAMPylation switch in human and bacterial FIC proteins.
Nat Commun, 10, 2019
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2C3V
 | | Structure of iodinated CBM25 from Bacillus halodurans amylase | | Descriptor: | ALPHA-AMYLASE G-6, IODIDE ION | | Authors: | Boraston, A.B, Healey, M, Klassen, J, Ficko-Blean, E, Lammerts van Bueren, A, Law, V. | | Deposit date: | 2005-10-12 | | Release date: | 2005-10-17 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.39 Å) | | Cite: | A Structural and Functional Analysis of Alpha-Glucan Recognition by Family 25 and 26 Carbohydrate-Binding Modules Reveals a Conserved Mode of Starch Recognition
J.Biol.Chem., 281, 2006
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5WQJ
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5O77
 | | Klebsiella pneumoniae OmpK35 | | Descriptor: | (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, OmpK35 | | Authors: | van den berg, B, Pathania, M, Zahn, M. | | Deposit date: | 2017-06-08 | | Release date: | 2018-06-20 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Getting Drugs into Gram-Negative Bacteria: Rational Rules for Permeation through General Porins.
Acs Infect Dis., 4, 2018
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5NWC
 | | Crystal structure of TNKS2 in complex with 2-(2-aminophenyl)-3,4-dihydroquinazolin-4-one | | Descriptor: | 2-(2-aminophenyl)-3~{H}-quinazolin-4-one, GLYCEROL, SULFATE ION, ... | | Authors: | Nkizinkiko, Y, Haikarainen, T, Lehtio, L. | | Deposit date: | 2017-05-05 | | Release date: | 2018-05-02 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | 2-Phenylquinazolinones as dual-activity tankyrase-kinase inhibitors.
Sci Rep, 8, 2018
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5O7G
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5NWL
 | | Crystal structure of a human RAD51-ATP filament. | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, DNA repair protein RAD51 homolog 1, MAGNESIUM ION | | Authors: | Pellegrini, L, Moschetti, T. | | Deposit date: | 2017-05-06 | | Release date: | 2018-03-07 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (3.93 Å) | | Cite: | Two distinct conformational states define the interaction of human RAD51-ATP with single-stranded DNA.
EMBO J., 37, 2018
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4ZTA
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5NXN
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4ZXC
 | | Crystal Structure of hydroquinone 1,2-dioxygenase PnpCD in complex with Fe3+ | | Descriptor: | FE (III) ION, Hydroquinone dioxygenase large subunit, Hydroquinone dioxygenase small subunit | | Authors: | Liu, S, Su, T, Zhang, C, Gu, L. | | Deposit date: | 2015-05-20 | | Release date: | 2015-09-02 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (3.05 Å) | | Cite: | Crystal Structure of PnpCD, a Two-subunit Hydroquinone 1,2-Dioxygenase, Reveals a Novel Structural Class of Fe2+-dependent Dioxygenases.
J.Biol.Chem., 290, 2015
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2C4X
 | | Structural basis for the promiscuous specificity of the carbohydrate- binding modules from the beta-sandwich super family | | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, ENDOGLUCANASE | | Authors: | Najmudin, S, Guerreiro, C.I.P.D, Carvalho, A.L, Bolam, D.N, Prates, J.A.M, Correia, M.A.S, Alves, V.D, Ferreira, L.M.A, Romao, M.J, Gilbert, H.J, Fontes, C.M.G.A. | | Deposit date: | 2005-10-25 | | Release date: | 2005-10-27 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Xyloglucan is Recognized by Carbohydrate-Binding Modules that Interact with Beta-Glucan Chains.
J.Biol.Chem., 281, 2006
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5NYI
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4ZXS
 | | HSV-1 nuclear egress complex | | Descriptor: | CHLORIDE ION, NICKEL (II) ION, SODIUM ION, ... | | Authors: | Bigalke, J.M, Heldwein, E.E. | | Deposit date: | 2015-05-20 | | Release date: | 2015-11-11 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.772 Å) | | Cite: | Structural basis of membrane budding by the nuclear egress complex of herpesviruses.
Embo J., 34, 2015
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4ZY7
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5NZB
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4ZUA
 | | Crystal structure of the ExsA regulatory domain | | Descriptor: | Exoenzyme S synthesis regulatory protein ExsA | | Authors: | Schubot, F.D. | | Deposit date: | 2015-05-15 | | Release date: | 2016-02-03 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structural Analysis of the Regulatory Domain of ExsA, a Key Transcriptional Regulator of the Type Three Secretion System in Pseudomonas aeruginosa.
Plos One, 10, 2015
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5OC9
 | | Crystal Structure of human TMEM16K / Anoctamin 10 | | Descriptor: | (2R)-2,3-dihydroxypropyl (7Z)-hexadec-7-enoate, Anoctamin-10, CALCIUM ION | | Authors: | Bushell, S.R, Pike, A.C.W, Chu, A, Tessitore, A, Rotty, B, Mukhopadhyay, S, Kupinska, K, Shrestha, L, Borkowska, O, Chalk, R, Burgess-Brown, N.A, Love, J, Edwards, A.M, Arrowsmith, C.H, Bountra, C, Carpenter, E.P, Structural Genomics Consortium (SGC) | | Deposit date: | 2017-06-29 | | Release date: | 2018-07-25 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | The structural basis of lipid scrambling and inactivation in the endoplasmic reticulum scramblase TMEM16K.
Nat Commun, 10, 2019
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3V00
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4ZZH
 | | SIRT1/Activator Complex | | Descriptor: | (4S)-N-[3-(1,3-oxazol-5-yl)phenyl]-7-[3-(trifluoromethyl)phenyl]-3,4-dihydro-1,4-methanopyrido[2,3-b][1,4]diazepine-5(2H)-carboxamide, NAD-dependent protein deacetylase sirtuin-1, ZINC ION | | Authors: | Dai, H. | | Deposit date: | 2015-05-22 | | Release date: | 2015-07-15 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (3.1001 Å) | | Cite: | Crystallographic structure of a small molecule SIRT1 activator-enzyme complex.
Nat Commun, 6, 2015
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