5O9V
 
 | | HsNMT1 in complex with CoA and Myristoylated-GGCFSKPK octapeptide | | Descriptor: | Apoptosis-inducing factor 3, CHLORIDE ION, COENZYME A, ... | | Authors: | Dian, C, Meinnel, T, Giglione, C. | | Deposit date: | 2017-06-20 | | Release date: | 2018-06-27 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.201 Å) | | Cite: | Structural and genomic decoding of human and plant myristoylomes reveals a definitive recognition pattern.
Nat. Chem. Biol., 14, 2018
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5O9T
 | | HsNMT1 in complex with CoA and acetylated-NCFSKPK peptide | | Descriptor: | 1IP-CYS-PHE-SER-LYS-PRO-ARG, CHLORIDE ION, GLYCEROL, ... | | Authors: | Dian, C, Meinnel, T, Giglione, C. | | Deposit date: | 2017-06-20 | | Release date: | 2018-06-27 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | Structural and genomic decoding of human and plant myristoylomes reveals a definitive recognition pattern.
Nat. Chem. Biol., 14, 2018
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5O9U
 | | HsNMT1 in complex with CoA and Myristoylated-GCSVSKKK octapeptide | | Descriptor: | COENZYME A, Calcineurin B-like protein 4, GLYCEROL, ... | | Authors: | Dian, C, Meinnel, T, Giglione, C. | | Deposit date: | 2017-06-20 | | Release date: | 2018-06-27 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Structural and genomic decoding of human and plant myristoylomes reveals a definitive recognition pattern.
Nat. Chem. Biol., 14, 2018
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6NFW
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6YLY
 | | pre-60S State NE2 (TAP-Flag-Nop53) | | Descriptor: | 25S rRNA, 5.8S rRNA, 60S ribosomal protein L13-A, ... | | Authors: | Kater, L, Beckmann, R. | | Deposit date: | 2020-04-07 | | Release date: | 2020-07-29 | | Last modified: | 2020-09-02 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Construction of the Central Protuberance and L1 Stalk during 60S Subunit Biogenesis.
Mol.Cell, 79, 2020
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4EY8
 | | Crystal structure of recombinant human acetylcholinesterase in complex with fasciculin-2 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Acetylcholinesterase, Fasciculin-2, ... | | Authors: | Cheung, J, Rudolph, M, Burshteyn, F, Cassidy, M, Gary, E, Love, J, Height, J, Franklin, M. | | Deposit date: | 2012-05-01 | | Release date: | 2012-10-17 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.5958 Å) | | Cite: | Structures of human acetylcholinesterase in complex with pharmacologically important ligands.
J.Med.Chem., 55, 2012
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6YLX
 | | pre-60S State NE1 (TAP-Flag-Nop53) | | Descriptor: | 25S rRNA, 27S pre-rRNA (guanosine(2922)-2'-O)-methyltransferase, 5.8S rRNA, ... | | Authors: | Kater, L, Beckmann, R. | | Deposit date: | 2020-04-07 | | Release date: | 2020-07-29 | | Last modified: | 2020-09-02 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Construction of the Central Protuberance and L1 Stalk during 60S Subunit Biogenesis.
Mol.Cell, 79, 2020
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7U0H
 | | State NE1 nucleolar 60S ribosome biogenesis intermediate - Overall model | | Descriptor: | 25S rRNA, 27S pre-rRNA (guanosine(2922)-2'-O)-methyltransferase, 5.8S rRNA, ... | | Authors: | Cruz, V.E, Sekulski, K, Peddada, N, Erzberger, J.P. | | Deposit date: | 2022-02-18 | | Release date: | 2022-12-14 | | Last modified: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (2.76 Å) | | Cite: | Sequence-specific remodeling of a topologically complex RNP substrate by Spb4.
Nat.Struct.Mol.Biol., 29, 2022
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7UQB
 | | Nucleoplasmic pre-60S intermediate of the Nog2 containing pre-rotation state from a SPB1-D52A strain with AlF4 | | Descriptor: | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 25S rRNA, 5.8S rRNA, ... | | Authors: | Sekulski, K, Cruz, V.E, Weirich, C.S, Erzberger, J.P. | | Deposit date: | 2022-04-19 | | Release date: | 2023-03-15 | | Last modified: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (2.43 Å) | | Cite: | rRNA methylation by Spb1 regulates the GTPase activity of Nog2 during 60S ribosomal subunit assembly.
Nat Commun, 14, 2023
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7UOO
 | | Nucleoplasmic pre-60S intermediate of the Nog2 containing pre-rotation state | | Descriptor: | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 25S rRNA, 5.8S rRNA, ... | | Authors: | Sekulski, K, Cruz, V.E, Weirich, C.S, Erzberger, J.P. | | Deposit date: | 2022-04-13 | | Release date: | 2023-03-15 | | Last modified: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (2.34 Å) | | Cite: | rRNA methylation by Spb1 regulates the GTPase activity of Nog2 during 60S ribosomal subunit assembly.
Nat Commun, 14, 2023
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7UQZ
 | | Nucleoplasmic pre-60S intermediate of the Nog2 containing pre-rotation state from a SPB1 D52A strain | | Descriptor: | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 25S rRNA, 5.8S rRNA, ... | | Authors: | Sekulski, K, Cruz, V.E, Weirich, C.S, Erzberger, J.P. | | Deposit date: | 2022-04-20 | | Release date: | 2023-03-15 | | Last modified: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (2.44 Å) | | Cite: | rRNA methylation by Spb1 regulates the GTPase activity of Nog2 during 60S ribosomal subunit assembly.
Nat Commun, 14, 2023
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7V08
 | | Nucleoplasmic pre-60S intermediate of the Nog2 containing pre-rotation state from a Spb1 D52A suppressor 3 strain | | Descriptor: | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 25S rRNA, 5.8S rRNA, ... | | Authors: | Sekulski, K, Cruz, V.E, Weirich, C.S, Erzberger, J.P. | | Deposit date: | 2022-05-10 | | Release date: | 2023-03-15 | | Last modified: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (2.36 Å) | | Cite: | rRNA methylation by Spb1 regulates the GTPase activity of Nog2 during 60S ribosomal subunit assembly.
Nat Commun, 14, 2023
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4P2I
 | | Crystal structure of the mouse SNX19 PX domain | | Descriptor: | MKIAA0254 protein | | Authors: | Collins, B.M. | | Deposit date: | 2014-03-04 | | Release date: | 2014-09-03 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structural Basis for Different Phosphoinositide Specificities of the PX Domains of Sorting Nexins Regulating G-protein Signaling.
J.Biol.Chem., 289, 2014
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4ZS9
 | | Raffinose and panose binding protein from Bifidobacterium animalis subsp. lactis Bl-04, bound with raffinose | | Descriptor: | CHLORIDE ION, MAGNESIUM ION, Sugar binding protein of ABC transporter system, ... | | Authors: | Fredslund, F, Ejby, M, Andersen, J.M, Slotboom, D.J, Abou Hachem, M. | | Deposit date: | 2015-05-13 | | Release date: | 2016-06-29 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.37 Å) | | Cite: | An ATP Binding Cassette Transporter Mediates the Uptake of alpha-(1,6)-Linked Dietary Oligosaccharides in Bifidobacterium and Correlates with Competitive Growth on These Substrates.
J. Biol. Chem., 291, 2016
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5A23
 | | SdsA sulfatase triclinic form | | Descriptor: | SDS HYDROLASE SDSA1, ZINC ION | | Authors: | De la Mora, E, Flores-Hernandez, E, Jakoncik, J, Stojanoff, V, Sanchez-Puig, N, Moreno, A. | | Deposit date: | 2015-05-11 | | Release date: | 2015-10-07 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.41 Å) | | Cite: | Sdsa Polymorph Isolation and Improvement of Their Crystal Quality Using Nonconventional Crystallization Techniques
J.Appl.Crystallogr., 48, 2015
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4P2J
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5A87
 | | Crystal structure of the metallo-beta-lactamase VIM-5 | | Descriptor: | GLYCEROL, METALLO-BETA-LACTAMASE VIM-5, ZINC ION | | Authors: | Brem, J, Duzgun, A.O, McDonough, M.A, Schofield, C.J. | | Deposit date: | 2015-07-13 | | Release date: | 2015-12-23 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Comparison of Verona Integron-Borne Metallo-beta-Lactamase (VIM) Variants Reveals Differences in Stability and Inhibition Profiles.
Antimicrob. Agents Chemother., 60, 2015
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4ZZE
 | | Raffinose and panose binding protein from Bifidobacterium animalis subsp. lactis Bl-04, bound with panose | | Descriptor: | CHLORIDE ION, MAGNESIUM ION, Sugar binding protein of ABC transporter system, ... | | Authors: | Fredslund, F, Ejby, M, Andersen, J.M, Slotboom, D.J, Hachem, M.A. | | Deposit date: | 2015-05-22 | | Release date: | 2016-06-29 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.76 Å) | | Cite: | An ATP Binding Cassette Transporter Mediates the Uptake of alpha-(1,6)-Linked Dietary Oligosaccharides in Bifidobacterium and Correlates with Competitive Growth on These Substrates.
J. Biol. Chem., 291, 2016
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4ZZA
 | | Raffinose and panose binding protein from Bifidobacterium animalis subsp. lactis Bl-04, bound with raffinose, selenomethionine derivative | | Descriptor: | Sugar binding protein of ABC transporter system, alpha-D-galactopyranose-(1-6)-alpha-D-glucopyranose-(1-2)-beta-D-fructofuranose | | Authors: | Fredslund, F, Ejby, M, Andersen, J.M, Slotboom, D.J, Abou Hachem, M. | | Deposit date: | 2015-05-22 | | Release date: | 2016-06-29 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.02 Å) | | Cite: | An ATP Binding Cassette Transporter Mediates the Uptake of alpha-(1,6)-Linked Dietary Oligosaccharides in Bifidobacterium and Correlates with Competitive Growth on These Substrates.
J. Biol. Chem., 291, 2016
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3BL6
 | | Crystal structure of Staphylococcus aureus 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase in complex with formycin A | | Descriptor: | (1S)-1-(7-amino-1H-pyrazolo[4,3-d]pyrimidin-3-yl)-1,4-anhydro-D-ribitol, 5'-methylthioadenosine nucleosidase/S-adenosylhomocysteine nucleosidase | | Authors: | Siu, K.K.W, Lee, J.E, Smith, G.D, Horvatin, C, Howell, P.L. | | Deposit date: | 2007-12-10 | | Release date: | 2008-06-10 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Structure of Staphylococcus aureus 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase
Acta Crystallogr.,Sect.F, 64, 2008
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6EM1
 | | State C (Nsa1-TAP Flag-Ytm1) - Visualizing the assembly pathway of nucleolar pre-60S ribosomes | | Descriptor: | 25S ribosomal RNA, 5.8S ribosomal RNA, 60S ribosomal protein L13-A, ... | | Authors: | Kater, L, Cheng, J, Barrio-Garcia, C, Hurt, E, Beckmann, R. | | Deposit date: | 2017-10-01 | | Release date: | 2017-12-27 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Visualizing the Assembly Pathway of Nucleolar Pre-60S Ribosomes.
Cell, 171, 2017
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6EM3
 | | State A architectural model (Nsa1-TAP Flag-Ytm1) - Visualizing the assembly pathway of nucleolar pre-60S ribosomes | | Descriptor: | 25S ribosomal RNA, 5.8S ribosomal RNA, 60S ribosomal protein L13-A, ... | | Authors: | Kater, L, Cheng, J, Barrio-Garcia, C, Hurt, E, Beckmann, R. | | Deposit date: | 2017-10-01 | | Release date: | 2017-12-27 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Visualizing the Assembly Pathway of Nucleolar Pre-60S Ribosomes.
Cell, 171, 2017
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5Z3G
 | | Cryo-EM structure of a nucleolar pre-60S ribosome (Rpf1-TAP) | | Descriptor: | 25S rRNA, 5.8S rRNA, 60S ribosomal protein L13-A, ... | | Authors: | Zhu, X, Zhou, D, Ye, K. | | Deposit date: | 2018-01-06 | | Release date: | 2018-04-11 | | Last modified: | 2019-11-06 | | Method: | ELECTRON MICROSCOPY (3.65 Å) | | Cite: | Cryo-EM structure of an early precursor of large ribosomal subunit reveals a half-assembled intermediate.
Protein Cell, 10, 2019
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6CEZ
 | | Crystal Structure of Rabbit Anti-HIV-1 gp120 V2 Fab 16C2 in complex with V2 peptide ConB | | Descriptor: | HIV-1 gp120 V2 Peptide Con B, Heavy chain of Fab fragment of rabbit anti-HIV1 gp120 V2 mAb 16C2, Light chain of Fab fragment of rabbit anti-HIV1 gp120 V2 mAb 16C2 | | Authors: | Kong, X, Pan, R. | | Deposit date: | 2018-02-13 | | Release date: | 2018-09-12 | | Last modified: | 2019-12-18 | | Method: | X-RAY DIFFRACTION (2.399 Å) | | Cite: | Select gp120 V2 domain specific antibodies derived from HIV and SIV infection and vaccination inhibit gp120 binding to alpha 4 beta 7.
PLoS Pathog., 14, 2018
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3UW4
 | | Crystal structure of cIAP1 BIR3 bound to GDC0152 | | Descriptor: | Baculoviral IAP repeat-containing protein 2, Baculoviral IAP repeat-containing protein 4, GDC0152, ... | | Authors: | Maurer, B, Hymowitz, S. | | Deposit date: | 2011-11-30 | | Release date: | 2012-02-22 | | Last modified: | 2023-12-06 | | Method: | X-RAY DIFFRACTION (1.79 Å) | | Cite: | Discovery of a Potent Small-Molecule Antagonist of Inhibitor of Apoptosis (IAP) Proteins and Clinical Candidate for the Treatment of Cancer (GDC-0152).
J.Med.Chem., 55, 2012
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