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4V4I
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Crystal Structure of a 70S Ribosome-tRNA Complex Reveals Functional Interactions and Rearrangements.
Descriptor: 16S SMALL SUBUNIT RIBOSOMAL RNA, 23S LARGE SUBUNIT RIBOSOMAL RNA, 30S ribosomal protein S10, ...
Authors:Korostelev, A, Trakhanov, S, Laurberg, M, Noller, H.F.
Deposit date:2007-02-15
Release date:2014-07-09
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (3.71 Å)
Cite:Crystal Structure of a 70S Ribosome-tRNA Complex Reveals Functional Interactions and Rearrangements
Cell(Cambridge,Mass.), 126, 2006
4V4W
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BU of 4v4w by Molmil
Structure of a SecM-stalled E. coli ribosome complex obtained by fitting atomic models for RNA and protein components into cryo-EM map EMD-1143
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal subunit protein S10, ...
Authors:Mitra, K, Frank, J.
Deposit date:2006-05-09
Release date:2014-07-09
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (15 Å)
Cite:Elongation arrest by SecM via a cascade of ribosomal RNA rearrangements
Mol.Cell, 22, 2006
4V5F
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BU of 4v5f by Molmil
The structure of the ribosome with elongation factor G trapped in the post-translocational state
Descriptor: 16S ribosomal RNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ...
Authors:Gao, Y.-G, Selmer, M, Dunham, C.M, Weixlbaumer, A, Kelley, A.C, Ramakrishnan, V.
Deposit date:2009-09-01
Release date:2014-07-09
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:The structure of the ribosome with elongation factor G trapped in the posttranslocational state.
Science, 326, 2009
3QE3
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BU of 3qe3 by Molmil
Sheep liver sorbitol dehydrogenase
Descriptor: ACETIC ACID, GLYCEROL, Sorbitol dehydrogenase, ...
Authors:Yennawar, N.H, Yennawar, H.P.
Deposit date:2011-01-19
Release date:2011-04-27
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:X-ray crystal structure and small-angle X-ray scattering of sheep liver sorbitol dehydrogenase.
Acta Crystallogr.,Sect.D, 67, 2011
7KPG
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BU of 7kpg by Molmil
Blocking Fab 25 anti-SIRP-alpha antibody in complex with SIRP-alpha Variant 1
Descriptor: Heavy chain of Fab 25 anti-SIRP-alpha antibody, Light chain of Fab 25 anti-SIRP-alpha antibody, SULFATE ION, ...
Authors:Sim, J, Pons, J.
Deposit date:2020-11-11
Release date:2020-12-16
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:Targeting the myeloid checkpoint receptor SIRP alpha potentiates innate and adaptive immune responses to promote anti-tumor activity.
J Hematol Oncol, 13, 2020
3EK9
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BU of 3ek9 by Molmil
SPRY Domain-containing SOCS Box Protein 2: Crystal Structure and Residues Critical for Protein Binding
Descriptor: GLYCEROL, SPRY domain-containing SOCS box protein 2
Authors:Kuang, Z, Yao, S, Xu, Y, Garrett, T.J.P, Norton, R.S.
Deposit date:2008-09-19
Release date:2009-02-24
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:SPRY domain-containing SOCS box protein 2: crystal structure and residues critical for protein binding.
J.Mol.Biol., 386, 2009
3LUH
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BU of 3luh by Molmil
Crystal structure of MID domain from hAGO2 in complex with GMP
Descriptor: GUANOSINE-5'-MONOPHOSPHATE, PHOSPHATE ION, Protein argonaute-2
Authors:Frank, F, Sonenberg, N, Nagar, B.
Deposit date:2010-02-17
Release date:2010-05-26
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.999 Å)
Cite:Structural basis for 5'-nucleotide base-specific recognition of guide RNA by human AGO2.
Nature, 465, 2010
3EOR
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BU of 3eor by Molmil
Crystal structure of 2C-methyl-D-erythritol 2,4-clycodiphosphate synthase complexed with ligand
Descriptor: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, GERANYL DIPHOSPHATE, SODIUM ION, ...
Authors:Hunter, W.N, Ramsden, N.L, Dawson, A.
Deposit date:2008-09-29
Release date:2009-08-25
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:A structure-based approach to ligand discovery for 2C-methyl-D-erythritol-2,4-cyclodiphosphate synthase: a target for antimicrobial therapy
J.Med.Chem., 52, 2009
3EPI
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BU of 3epi by Molmil
Structure of Human DNA Polymerase Iota complexed with N2-ethylguanine and incoming TTP
Descriptor: 5'-D(*DTP*DCP*DTP*(2EG)P*DGP*DGP*DGP*DTP*DCP*DCP*DTP*DAP*DGP*DGP*DAP*DCP*DCP*(DOC))-3', DNA polymerase iota, PHOSPHATE ION, ...
Authors:Pence, M.G.
Deposit date:2008-09-29
Release date:2008-12-16
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Lesion bypass of N2-ethylguanine by human DNA polymerase iota.
J.Biol.Chem., 284, 2009
3ERF
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BU of 3erf by Molmil
Crystal structure of Gtt2 from Saccharomyces cerevisiae
Descriptor: Glutathione S-transferase 2
Authors:Ma, X.X, Jiang, Y.L, He, Y.X, Chen, Y.X, Zhou, C.Z.
Deposit date:2008-10-02
Release date:2009-10-13
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:Structures of yeast glutathione-S-transferase Gtt2 reveal a new catalytic type of GST family.
Embo Rep., 10, 2009
3E8T
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Crystal Structure of Epiphyas postvittana Takeout 1
Descriptor: Takeout-like protein 1, Ubiquinone-8
Authors:Hamiaux, C, Stanley, D, Greenwood, D.R, Baker, E.N, Newcomb, R.D.
Deposit date:2008-08-20
Release date:2008-12-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Crystal structure of Epiphyas postvittana takeout 1 with bound ubiquinone supports a role as ligand carriers for takeout proteins in insects
J.Biol.Chem., 284, 2009
1PCJ
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BU of 1pcj by Molmil
Enzyme-ligand complex of P. aeruginosa PMM/PGM
Descriptor: 1-O-phosphono-alpha-D-mannopyranose, Phosphomannomutase, ZINC ION
Authors:Regni, C, Tipton, P.A, Beamer, L.J.
Deposit date:2003-05-16
Release date:2004-01-20
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis of diverse substrate recognition by the enzyme PMM/PGM from P. aeruginosa.
Structure, 12, 2004
3QX8
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BU of 3qx8 by Molmil
Crystal structure of MID domain from hAGO2 in complex with m7GpppG
Descriptor: 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE, Protein argonaute-2
Authors:Frank, F, Fabian, M.R, Stepinski, J, Jemielity, J, Darzynkiewicz, E, Sonenberg, N, Nagar, B.
Deposit date:2011-03-01
Release date:2011-04-20
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural analysis of 5'-mRNA-cap interactions with the human AGO2 MID domain.
Embo Rep., 12, 2011
3EB5
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BU of 3eb5 by Molmil
Structure of the cIAP2 RING domain
Descriptor: Baculoviral IAP repeat-containing protein 3, SODIUM ION, ZINC ION
Authors:Mace, P.D, Linke, K, Smith, C.A, Day, C.L.
Deposit date:2008-08-27
Release date:2008-09-09
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structures of the cIAP2 RING domain reveal conformational changes associated with ubiquitin-conjugating enzyme (E2) recruitment.
J.Biol.Chem., 283, 2008
3EHR
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BU of 3ehr by Molmil
Crystal Structure of Human Osteoclast Stimulating Factor
Descriptor: Osteoclast-stimulating factor 1
Authors:Tong, S, Zhou, H, Gao, Y, Zhu, Z, Zhang, X, Teng, M, Niu, L.
Deposit date:2008-09-14
Release date:2009-08-04
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal structure of human osteoclast stimulating factor
Proteins, 75, 2009
3EIY
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BU of 3eiy by Molmil
Crystal structure of inorganic pyrophosphatase from burkholderia pseudomallei with bound pyrophosphate
Descriptor: DI(HYDROXYETHYL)ETHER, Inorganic pyrophosphatase, POTASSIUM ION, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2008-09-17
Release date:2008-09-30
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The role of medical structural genomics in discovering new drugs for infectious diseases.
PLoS Comput Biol, 5, 2009
3ENN
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BU of 3enn by Molmil
2.1A crystal structure of glucose/ribitol dehydrogenase from brucella melitensis (p43212)
Descriptor: GLUCOSE/RIBITOL DEHYDROGENASE
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2008-09-25
Release date:2008-11-25
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:2.1A crystal structure of glucose/ribitol dehydrogenase from brucella melitensis (p43212)
To be Published
3ESK
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BU of 3esk by Molmil
Structure of HOP TPR2A domain in complex with the non-cognate Hsc70 peptide ligand
Descriptor: Heat shock cognate 71 kDa protein, NICKEL (II) ION, Stress-induced-phosphoprotein 1
Authors:Kajander, T, Regan, L.
Deposit date:2008-10-06
Release date:2009-07-07
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Electrostatic interactions of Hsp-organizing protein tetratricopeptide domains with Hsp70 and Hsp90: computational analysis and protein engineering.
J.Biol.Chem., 284, 2009
3E8L
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BU of 3e8l by Molmil
The Crystal Structure of the Double-headed Arrowhead Protease Inhibitor A in Complex with Two Trypsins
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, CALCIUM ION, ...
Authors:Bao, R, Jiang, C.-H, Chi, C.W, Lin, S.X, Chen, Y.X.
Deposit date:2008-08-20
Release date:2009-07-28
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.48 Å)
Cite:The ternary structure of double-headed arrowhead protease inhibitor API-A complexed with two trypsins reveals a novel reactive site conformation.
J.Biol.Chem., 284, 2009
3RJE
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BU of 3rje by Molmil
Ternary complex of DNA Polymerase Beta with a gapped DNA containing 8odG at template position
Descriptor: DNA (5'-D(*CP*CP*GP*AP*CP*(8OG)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), DNA (5'-D(P*GP*TP*CP*GP*G)-3'), ...
Authors:Batra, V.K, Beard, W.A, Wilson, S.H.
Deposit date:2011-04-15
Release date:2012-01-18
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Binary complex crystal structure of DNA polymerase beta reveals multiple conformations of the templating 8-oxoguanine lesion
Proc.Natl.Acad.Sci.USA, 109, 2012
3E5Y
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BU of 3e5y by Molmil
Crystal structure of TrmH family RNA methyltransferase from Burkholderia pseudomallei
Descriptor: TrmH family RNA methyltransferase
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2008-08-14
Release date:2008-08-26
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of TrmH family RNA methyltransferase from Burkholderia pseudomallei
To be Published
3R0Q
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BU of 3r0q by Molmil
A Uniquely Open Conformation Revealed in the Crystal Structure of Arabidopsis Thaliana Protein Arginine Methyltransferase 10
Descriptor: Probable protein arginine N-methyltransferase 4.2, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Cheng, Y, Redinbo, M.R.
Deposit date:2011-03-08
Release date:2011-10-19
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.61 Å)
Cite:Crystal structure of the plant epigenetic protein arginine methyltransferase 10.
J.Mol.Biol., 414, 2011
3EQY
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BU of 3eqy by Molmil
Crystal structure of human MDMX in complex with a 12-mer peptide inhibitor
Descriptor: 12-mer peptide inhibitor, GUANIDINE, Mdm4 protein, ...
Authors:Pazgier, M, Lu, W.
Deposit date:2008-10-01
Release date:2009-03-17
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:Structural basis for high-affinity peptide inhibition of p53 interactions with MDM2 and MDMX.
Proc.Natl.Acad.Sci.USA, 106, 2009
3EQS
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BU of 3eqs by Molmil
Crystal structure of human MDM2 in complex with a 12-mer peptide inhibitor
Descriptor: 12-mer peptide inhibitor, E3 ubiquitin-protein ligase Mdm2, GUANIDINE
Authors:Pazgier, M, Lu, W.
Deposit date:2008-10-01
Release date:2009-03-17
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structural basis for high-affinity peptide inhibition of p53 interactions with MDM2 and MDMX.
Proc.Natl.Acad.Sci.USA, 106, 2009
3RH6
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BU of 3rh6 by Molmil
DNA Polymerase Beta Mutant (Y271) with a dideoxy-terminated primer with an incoming ribonucleotide (rCTP)
Descriptor: (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*(DDG))-3'), (5'-D(P*GP*TP*CP*GP*G)-3'), 5'-D(*CP*CP*GP*AP*CP*GP*CP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', ...
Authors:Cavanaugh, N.A, Beard, W.A, Batra, V.K, Perera, L, Pedersen, L.G, Wilson, S.H.
Deposit date:2011-04-11
Release date:2011-07-06
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.048 Å)
Cite:Molecular insights into DNA polymerase deterrents for ribonucleotide insertion.
J.Biol.Chem., 286, 2011

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數據於2024-09-25公開中

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