6GNG
 
 | | Granule Bound Starch Synthase I from Cyanophora paradoxa bound to acarbose and ADP | | Descriptor: | 4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranose, ADENOSINE-5'-DIPHOSPHATE, Granule-bound starch synthase | | Authors: | Cuesta-Seijo, J.A, Nielsen, M.M, Palcic, M.M. | | Deposit date: | 2018-05-30 | | Release date: | 2018-07-25 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.95 Å) | | Cite: | Crystal Structures of theCatalyticDomain ofArabidopsis thalianaStarch Synthase IV, of Granule Bound Starch Synthase From CLg1 and of Granule Bound Starch Synthase I ofCyanophora paradoxaIllustrate Substrate Recognition in Starch Synthases.
Front Plant Sci, 9, 2018
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6H6O
 | | UbiJ-SCP2 Ubiquinone synthesis protein | | Descriptor: | (2S)-2-hydroxybutanedioic acid, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ... | | Authors: | Fyfe, C.D, Legrand, P, Pecqueur, L, Ciccone, L, Lombard, M, Fontecave, M. | | Deposit date: | 2018-07-28 | | Release date: | 2019-02-13 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | A Soluble Metabolon Synthesizes the Isoprenoid Lipid Ubiquinone.
Cell Chem Biol, 26, 2019
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6GNF
 | | Granule Bound Starch Synthase from Cyanobacterium sp. CLg1 bound to acarbose and ADP | | Descriptor: | 4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranose, ADENOSINE-5'-DIPHOSPHATE, Glycogen synthase, ... | | Authors: | Cuesta-Seijo, J.A, Nielsen, M.M, Palcic, M.M. | | Deposit date: | 2018-05-30 | | Release date: | 2018-07-25 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Crystal Structures of theCatalyticDomain ofArabidopsis thalianaStarch Synthase IV, of Granule Bound Starch Synthase From CLg1 and of Granule Bound Starch Synthase I ofCyanophora paradoxaIllustrate Substrate Recognition in Starch Synthases.
Front Plant Sci, 9, 2018
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6H6N
 | | UbiJ-SCP2 Ubiquinone synthesis protein | | Descriptor: | CALCIUM ION, TERBIUM(III) ION, Ubiquinone biosynthesis protein UbiJ | | Authors: | Fyfe, C.D, Legrand, P, Pecqueur, L, Ciccone, L, Lombard, M, Fontecave, M. | | Deposit date: | 2018-07-28 | | Release date: | 2019-02-13 | | Last modified: | 2024-05-15 | | Method: | X-RAY DIFFRACTION (2.12 Å) | | Cite: | A Soluble Metabolon Synthesizes the Isoprenoid Lipid Ubiquinone.
Cell Chem Biol, 26, 2019
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6H6P
 | | UbiJ-SCP2 Ubiquinone synthesis protein | | Descriptor: | CALCIUM ION, PENTAETHYLENE GLYCOL, Ubiquinone biosynthesis protein UbiJ | | Authors: | Fyfe, C.D, Legrand, P, Pecqueur, L, Ciccone, L, Lombard, M, Fontecave, M. | | Deposit date: | 2018-07-28 | | Release date: | 2019-02-13 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | A Soluble Metabolon Synthesizes the Isoprenoid Lipid Ubiquinone.
Cell Chem Biol, 26, 2019
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6GNE
 | | Catalytic domain of Starch Synthase IV from Arabidopsis thaliana bound to ADP and acarbose | | Descriptor: | 4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, ADENOSINE-5'-DIPHOSPHATE, Probable starch synthase 4, ... | | Authors: | Cuesta-Seijo, J.A, Ruzanski, C, Krucewicz, K, Striebeck, A, Palcic, M.M. | | Deposit date: | 2018-05-30 | | Release date: | 2018-07-25 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.55 Å) | | Cite: | Crystal Structures of theCatalyticDomain ofArabidopsis thalianaStarch Synthase IV, of Granule Bound Starch Synthase From CLg1 and of Granule Bound Starch Synthase I ofCyanophora paradoxaIllustrate Substrate Recognition in Starch Synthases.
Front Plant Sci, 9, 2018
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6GSF
 | | Solution structure of lipase binding domain LID1 of foldase from Pseudomonas aeruginosa | | Descriptor: | Lipase chaperone | | Authors: | Viegas, A, Jaeger, K.-E, Etzkorn, M, Gohlke, H, Verma, N, Dollinger, P, Kovacic, F. | | Deposit date: | 2018-06-14 | | Release date: | 2018-12-26 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Structural and dynamic insights revealing how lipase binding domain MD1 of Pseudomonas aeruginosa foldase affects lipase activation.
Sci Rep, 10, 2020
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7B16
 | | TRPC4 in complex with inhibitor GFB-9289 | | Descriptor: | 2-(HEXADECANOYLOXY)-1-[(PHOSPHONOOXY)METHYL]ETHYL HEXADECANOATE, 5-chloranyl-4-(4-cyclohexyl-3-oxidanylidene-piperazin-1-yl)-1~{H}-pyridazin-6-one, CALCIUM ION, ... | | Authors: | Vinayagam, D, Quentin, D, Sistel, O, Merino, F, Stabrin, M, Hofnagel, O, Ledeboer, M.W, Malojcic, G, Raunser, S. | | Deposit date: | 2020-11-23 | | Release date: | 2020-12-09 | | Last modified: | 2024-05-01 | | Method: | ELECTRON MICROSCOPY (3.15 Å) | | Cite: | Structural basis of TRPC4 regulation by calmodulin and pharmacological agents.
Elife, 9, 2020
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7B0S
 | | TRPC4 in complex with inhibitor GFB-8438 | | Descriptor: | (2R)-3-(phosphonooxy)propane-1,2-diyl dihexanoate, 5-chloranyl-4-[3-oxidanylidene-4-[[2-(trifluoromethyl)phenyl]methyl]piperazin-1-yl]-1~{H}-pyridazin-6-one, CALCIUM ION, ... | | Authors: | Vinayagam, D, Quentin, D, Sistel, O, Merino, F, Stabrin, M, Hofnagel, O, Ledeboer, M.W, Malojcic, G, Raunser, S. | | Deposit date: | 2020-11-21 | | Release date: | 2020-12-09 | | Last modified: | 2024-05-01 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Structural basis of TRPC4 regulation by calmodulin and pharmacological agents.
Elife, 9, 2020
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3CWI
 | | Crystal structure of thiamine biosynthesis protein (ThiS) from Geobacter metallireducens. Northeast Structural Genomics Consortium Target GmR137 | | Descriptor: | Thiamine-biosynthesis protein ThiS | | Authors: | Forouhar, F, Abashidze, M, Seetharaman, J, Mao, L, Janjua, H, Xiao, R, Maglaqui, M, Ciccosanti, C, Foote, E.L, Wang, H, Everett, J.K, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2008-04-21 | | Release date: | 2008-05-06 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Crystal structure of thiamine biosynthesis protein (ThiS) from Geobacter metallireducens.
To be Published
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4M8G
 | | Crystal structure of Se-Met hN33/Tusc3 | | Descriptor: | Tumor suppressor candidate 3 | | Authors: | Mohorko, E, Owen, R.L, Malojcic, G, Brozzo, M.S, Aebi, M, Glockshuber, R. | | Deposit date: | 2013-08-13 | | Release date: | 2014-03-26 | | Last modified: | 2014-05-07 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural basis of substrate specificity of human oligosaccharyl transferase subunit n33/tusc3 and its role in regulating protein N-glycosylation.
Structure, 22, 2014
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4M90
 | | crystal structure of oxidized hN33/Tusc3 | | Descriptor: | Tumor suppressor candidate 3 | | Authors: | Mohorko, E, Owen, R.L, Malojcic, G, Brozzo, M.S, Aebi, M, Glockshuber, R. | | Deposit date: | 2013-08-14 | | Release date: | 2014-03-26 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Structural basis of substrate specificity of human oligosaccharyl transferase subunit n33/tusc3 and its role in regulating protein N-glycosylation.
Structure, 22, 2014
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5U38
 | | Crystal structure of native lectin from Platypodium elegans seeds (PELa) complexed with Man1-3Man-OMe. | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Lectin, ... | | Authors: | Silva, I.B, Araripe, D.A, Neco, A.H.B, Pinto-Junior, V.R, Osterne, V.J.S, Santiago, M.Q, Silva-Filho, J.C, Leal, R.B, Rocha, C.R.C, Nascimento, K.S, Cavada, B.S. | | Deposit date: | 2016-12-01 | | Release date: | 2017-10-04 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Structural studies and nociceptive activity of a native lectin from Platypodium elegans seeds (nPELa).
Int. J. Biol. Macromol., 107, 2018
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4L0R
 | | Crystal structure of FGF2-interacting protein from Homo sapiens. Northeast Structural Genomics Consortium Target HR9027A. | | Descriptor: | Centrosomal protein of 57 kDa | | Authors: | Seetharaman, J, Lew, S, Su, M, Ciccosanti, C, Sahdev, S, Acton, T.B, Xiao, R, Everett, J.K, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2013-05-31 | | Release date: | 2013-09-04 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.49 Å) | | Cite: | Crystal structure of FGF2-interacting protein from Homo sapiens. Northeast Structural Genomics consortium id HR9027A
To be Published
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7C5D
 | | Crystal structure of TRF2 TRFH domain in complex with a MCPH1 peptide | | Descriptor: | GLYCEROL, Microcephalin, Telomeric repeat-binding factor 2 | | Authors: | Xiong, X, Chen, Y. | | Deposit date: | 2020-05-19 | | Release date: | 2020-10-21 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.151 Å) | | Cite: | Microcephalin 1/BRIT1-TRF2 interaction promotes telomere replication and repair, linking telomere dysfunction to primary microcephaly.
Nat Commun, 11, 2020
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4M91
 | | crystal structure of hN33/Tusc3-peptide 1 | | Descriptor: | Protein cereblon, Tumor suppressor candidate 3 | | Authors: | Mohorko, E, Owen, R.L, Malojcic, G, Brozzo, M.S, Aebi, M, Glockshuber, R. | | Deposit date: | 2013-08-14 | | Release date: | 2014-03-26 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.1 Å) | | Cite: | Structural basis of substrate specificity of human oligosaccharyl transferase subunit n33/tusc3 and its role in regulating protein N-glycosylation.
Structure, 22, 2014
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4M92
 | | Crystal structure of hN33/Tusc3-peptide 2 | | Descriptor: | Interleukin-1 receptor accessory protein-like 1, Tumor suppressor candidate 3 | | Authors: | Mohorko, E, Owen, R.L, Malojcic, G, Brozzo, M.S, Aebi, M, Glockshuber, R. | | Deposit date: | 2013-08-14 | | Release date: | 2014-03-26 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Structural basis of substrate specificity of human oligosaccharyl transferase subunit n33/tusc3 and its role in regulating protein N-glycosylation.
Structure, 22, 2014
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4NVS
 | | Crystal Structure of the Q18CP6_CLOD6 protein from glyoxalase family. Northeast Structural Genomics Consortium Target CfR3 | | Descriptor: | Putative enzyme, glyoxalase family | | Authors: | Vorobiev, S, Seetharaman, J, Sahdev, S, Xiao, R, Ciccosanti, C, Wang, H, Everett, J.K, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2013-12-05 | | Release date: | 2013-12-18 | | Method: | X-RAY DIFFRACTION (2.385 Å) | | Cite: | Crystal Structure of the Q18CP6_CLOD6 protein from glyoxalase family.
To be Published
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7NL4
 | | OsNIP2;1 silicon transporter from rice | | Descriptor: | Aquaporin NIP2-1, CADMIUM ION | | Authors: | van den Berg, B. | | Deposit date: | 2021-02-22 | | Release date: | 2021-11-03 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structural Basis for Silicic Acid Uptake by Higher Plants.
J.Mol.Biol., 433, 2021
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4MZV
 | | Crystal structure of extracellular part of human EpCAM | | Descriptor: | DECYL-BETA-D-MALTOPYRANOSIDE, Epithelial cell adhesion molecule | | Authors: | Pavsic, M, Guncar, G, Djinovic-Carugo, K, Lenarcic, B. | | Deposit date: | 2013-09-30 | | Release date: | 2014-08-27 | | Last modified: | 2019-12-25 | | Method: | X-RAY DIFFRACTION (1.865 Å) | | Cite: | Crystal structure and its bearing towards an understanding of key biological functions of EpCAM.
Nat Commun, 5, 2014
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4OVN
 | | Voltage-gated Sodium Channel 1.5 (Nav1.5) C-terminal domain in complex with Calmodulin poised for activation | | Descriptor: | Calmodulin, MAGNESIUM ION, PHOSPHATE ION, ... | | Authors: | Gabelli, S.B, Bianchet, M.A, Boto, A, Jakoncic, J, Tomaselli, G.F, Amzel, L.M. | | Deposit date: | 2013-12-10 | | Release date: | 2014-12-03 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Regulation of the NaV1.5 cytoplasmic domain by calmodulin.
Nat Commun, 5, 2014
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4N6C
 | | Crystal Structure of the B1RZQ2 protein from Streptococcus pneumoniae. Northeast Structural Genomics Consortium (NESG) Target SpR36. | | Descriptor: | BROMIDE ION, uncharacterized protein | | Authors: | Vorobiev, S, Seetharaman, J, Patel, D, Xiao, R, Ciccosanti, C, Wang, D, Everett, J.K, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2013-10-11 | | Release date: | 2013-10-30 | | Method: | X-RAY DIFFRACTION (1.548 Å) | | Cite: | Crystal Structure of the B1RZQ2 protein from Streptococcus pneumoniae.
To be Published
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1EF7
 | | CRYSTAL STRUCTURE OF HUMAN CATHEPSIN X | | Descriptor: | CATHEPSIN X | | Authors: | Guncar, G, Klemencic, I, Turk, B, Turk, V, Karaoglanovic-Carmona, A, Juliano, L, Turk, D. | | Deposit date: | 2000-02-07 | | Release date: | 2000-03-15 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.67 Å) | | Cite: | Crystal structure of cathepsin X: a flip-flop of the ring of His23 allows carboxy-monopeptidase and carboxy-dipeptidase activity of the protease.
Structure Fold.Des., 8, 2000
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8B1L
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2MAS
 | | PURINE NUCLEOSIDE HYDROLASE WITH A TRANSITION STATE INHIBITOR | | Descriptor: | 2-(4-AMINO-PHENYL)-5-HYDROXYMETHYL-PYRROLIDINE-3,4-DIOL, CALCIUM ION, INOSINE-URIDINE NUCLEOSIDE N-RIBOHYDROLASE | | Authors: | Degano, M, Schramm, V.L, Sacchettini, J.C. | | Deposit date: | 1996-10-17 | | Release date: | 1997-08-12 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Trypanosomal nucleoside hydrolase. A novel mechanism from the structure with a transition-state inhibitor.
Biochemistry, 37, 1998
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