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6EAM	CRYSTAL STRUCTURE OF HUMAN RESPIRATORY SYNCYTIAL VIRUS FUSION GLYCOPROTEIN INHIBITOR ESCAPE VARIANT E487D STABILIZED IN THE PREFUSION STATE Descriptor: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, D(-)-TARTARIC ACID, ... Authors: Battles, M.B, McLellan, J.S. Deposit date: 2018-08-03 Release date: 2019-08-07 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.739 Å) Cite: Structural Basis for Respiratory Syncytial Virus Fusion Inhibitor Resistance To be published
6EDU	B41 SOSIP.664 in complex with soluble CD4 (D1-D2), the co-receptor mimicking antibody 21c and the broadly neutralizing antibody 8ANC195 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 21c Fab VH domain, ... Authors: Barnes, C.O, Bjorkman, P.J. Deposit date: 2018-08-11 Release date: 2018-10-17 Last modified: 2020-07-29 Method: ELECTRON MICROSCOPY (4.06 Å) Cite: Partially Open HIV-1 Envelope Structures Exhibit Conformational Changes Relevant for Coreceptor Binding and Fusion. Cell Host Microbe, 24, 2018
4G7O	Crystal structure of Thermus thermophilus transcription initiation complex containing 2 nt of RNA Descriptor: 5'-D(*CP*CP*T*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*GP*G)-3', 5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*CP*AP*GP*G)-3', 5'-R(*GP*A)-3', ... Authors: Zhang, Y, Ebright, R.H. Deposit date: 2012-07-20 Release date: 2012-10-31 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.993 Å) Cite: Structural basis of transcription initiation. Science, 338, 2012
4GAW	Crystal structure of active human granzyme H Descriptor: CHLORIDE ION, Granzyme H, SULFATE ION Authors: Wang, L, Li, Q, Wu, L, Zhang, K, Tong, L, Sun, F, Fan, Z. Deposit date: 2012-07-25 Release date: 2013-01-16 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (3 Å) Cite: Identification of SERPINB1 as a physiological inhibitor of human granzyme H J.Immunol., 190, 2013
4OSD	Dimer of a C-terminal fragment of phage T4 gp5 beta-helix Descriptor: 9-OCTADECENOIC ACID, MAGNESIUM ION, PALMITIC ACID, ... Authors: Buth, S.A, Leiman, P.G, Shneider, M.M. Deposit date: 2014-02-12 Release date: 2015-02-18 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.96 Å) Cite: Structure and Biophysical Properties of a Triple-Stranded Beta-Helix Comprising the Central Spike of Bacteriophage T4. Viruses, 7, 2015
4OX9	Crystal structure of the aminoglycoside resistance methyltransferase NpmA bound to the 30S ribosomal subunit Descriptor: 16S rRNA, 16S rRNA (adenine(1408)-N(1))-methyltransferase, 30S ribosomal protein S10, ... Authors: Dunkle, J.A, Conn, G.L, Dunham, C.M. Deposit date: 2014-02-04 Release date: 2014-04-09 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (3.8035 Å) Cite: Molecular recognition and modification of the 30S ribosome by the aminoglycoside-resistance methyltransferase NpmA. Proc.Natl.Acad.Sci.USA, 111, 2014
4FW7	Crystal Structure of the LpxC in complex with N-[(2S,3R)-3-HYDROXY-1-(HYDROXYAMINO)-1-OXOBUTAN-2-YL]BIPHENYL-4-CARBOXAMIDE inhibitor Descriptor: ACETATE ION, GLYCEROL, N-[(2S,3R)-3-hydroxy-1-(hydroxyamino)-1-oxobutan-2-yl]biphenyl-4-carboxamide, ... Authors: Kang, Y.N, Stuckey, J.A. Deposit date: 2012-06-30 Release date: 2013-05-15 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Crystal Structure of the LpxC to be published
4FZB	Structure of thymidylate synthase ThyX complexed to a new inhibitor Descriptor: 2-hydroxy-3-(4-methoxybenzyl)naphthalene-1,4-dione, DIMETHYL SULFOXIDE, FLAVIN-ADENINE DINUCLEOTIDE, ... Authors: Basta, T, Boum, Y, Briffotaux, J, Becker, H.F, Lamarre-Jouenne, I, Lambry, J.C, Skouloubris, S, Liebl, U, van Tilbeurgh, H, Graille, M, Myllylkallio, H. Deposit date: 2012-07-06 Release date: 2013-05-22 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.59 Å) Cite: Mechanistic and structural basis for inhibition of thymidylate synthase ThyX. Open Biology, 2, 2012
4OKN	Crystal structure of human muscle L-lactate dehydrogenase, ternary complex with NADH and oxalate Descriptor: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, KANAMYCIN A, L-lactate dehydrogenase A chain, ... Authors: Kolappan, S, Craig, L. Deposit date: 2014-01-22 Release date: 2014-12-03 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Structures of lactate dehydrogenase A (LDHA) in apo, ternary and inhibitor-bound forms. Acta Crystallogr.,Sect.D, 71, 2015
4DV6	Crystal structure of the Thermus thermophilus 30S ribosomal subunit with a 16S rRNA mutation, A915G Descriptor: 16S rRNA, MAGNESIUM ION, ZINC ION, ... Authors: Demirci, H, Murphy IV, F, Murphy, E, Gregory, S.T, Dahlberg, A.E, Jogl, G. Deposit date: 2012-02-22 Release date: 2013-02-27 Method: X-RAY DIFFRACTION (3.297 Å) Cite: A structural basis for streptomycin resistance To be Published
4DR6	Crystal structure of the Thermus thermophilus (HB8) 30S ribosomal subunit with codon, near-cognate transfer RNA anticodon stem-loop mismatched at the first codon position and streptomycin bound Descriptor: 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... Authors: Demirci, H, Murphy IV, F, Murphy, E, Gregory, S.T, Dahlberg, A.E, Jogl, G. Deposit date: 2012-02-16 Release date: 2012-11-14 Last modified: 2013-01-30 Method: X-RAY DIFFRACTION (3.3 Å) Cite: A structural basis for streptomycin-induced misreading of the genetic code. Nat Commun, 4, 2013
4DV0	Crystal structure of the Thermus thermophilus 30S ribosomal subunit with a 16S rRNA mutation, U20G Descriptor: 16S rRNA, MAGNESIUM ION, ZINC ION, ... Authors: Demirci, H, Murphy IV, F, Murphy, E, Gregory, S.T, Dahlberg, A.E, Jogl, G. Deposit date: 2012-02-22 Release date: 2013-02-27 Method: X-RAY DIFFRACTION (3.853 Å) Cite: A structural basis for streptomycin resistance To be Published
4DYU	The crystal structure of DNA starvation/stationary phase protection protein Dps from Yersinia pestis KIM 10 Descriptor: DNA protection during starvation protein, SULFATE ION, ZINC ION Authors: Tan, K, Gu, M, Kwon, K, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) Deposit date: 2012-02-29 Release date: 2012-03-14 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.75 Å) Cite: The crystal structure of DNA starvation/stationary phase protection protein Dps from Yersinia pestis KIM 10 To be Published
4E2Q	Crystal Structure of (S)-Ureidoglycine Aminohydrolase from Arabidopsis thaliana Descriptor: MANGANESE (II) ION, Ureidoglycine aminohydrolase Authors: Shin, I, Rhee, S. Deposit date: 2012-03-09 Release date: 2012-04-18 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Structural and functional insights into (S)-ureidoglycine aminohydrolase, key enzyme of purine catabolism in Arabidopsis thaliana J.Biol.Chem., 287, 2012
4E1L	Crystal structure of Acetoacetyl-CoA thiolase (thlA2) from Clostridium difficile Descriptor: Acetoacetyl-CoA thiolase 2, IODIDE ION Authors: Anderson, S.M, Wawrzak, Z, Kudritska, M, Peterson, S.N, Anderson, W.F, Savchenko, A, Center for Structural Genomics of Infectious Diseases (CSGID) Deposit date: 2012-03-06 Release date: 2012-03-21 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2 Å) Cite:
4DV1	Crystal structure of the Thermus thermophilus 30S ribosomal subunit with a 16S rRNA mutation, U20G, bound with streptomycin Descriptor: 16S rRNA, MAGNESIUM ION, STREPTOMYCIN, ... Authors: Demirci, H, Murphy IV, F, Murphy, E, Gregory, S.T, Dahlberg, A.E, Jogl, G. Deposit date: 2012-02-22 Release date: 2013-02-27 Method: X-RAY DIFFRACTION (3.849 Å) Cite: A structural basis for streptomycin resistance To be Published
4DZ4	X-ray crystal structure of a hypothetical Agmatinase from Burkholderia thailandensis Descriptor: 1,2-ETHANEDIOL, Agmatinase, MANGANESE (II) ION, ... Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2012-02-29 Release date: 2012-03-28 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Combining functional and structural genomics to sample the essential Burkholderia structome. Plos One, 8, 2013
4E2S	Crystal structure of (S)-Ureidoglycine Aminohydrolase from Arabidopsis thaliana in complex with its substrate, (S)-Ureidoglycine Descriptor: (2S)-amino(carbamoylamino)ethanoic acid, MANGANESE (II) ION, Ureidoglycine aminohydrolase Authors: Shin, I, Rhee, S. Deposit date: 2012-03-09 Release date: 2012-04-18 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (2.59 Å) Cite: Structural and functional insights into (S)-ureidoglycine aminohydrolase, key enzyme of purine catabolism in Arabidopsis thaliana J.Biol.Chem., 287, 2012
4DX5	Transport of drugs by the multidrug transporter AcrB involves an access and a deep binding pocket that are separated by a switch-loop Descriptor: (4S,4AS,5AR,12AS)-4,7-BIS(DIMETHYLAMINO)-3,10,12,12A-TETRAHYDROXY-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDROTETRACENE-2- CARBOXAMIDE, Acriflavine resistance protein B, DARPIN, ... Authors: Eicher, T, Cha, H, Seeger, M.A, Brandstaetter, L, El-Delik, J, Bohnert, J.A, Kern, W.V, Verrey, F, Gruetter, M.G, Diederichs, K, Pos, K.M. Deposit date: 2012-02-27 Release date: 2012-05-02 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Transport of drugs by the multidrug transporter AcrB involves an access and a deep binding pocket that are separated by a switch-loop. Proc.Natl.Acad.Sci.USA, 109, 2012
4P3B	Crystal structure of the mouse C5a-desArg anaphylatoxin Descriptor: Complement C5, FORMIC ACID Authors: Yatime, L, Schatz-Jakobsen, J.A, Andersen, G.R. Deposit date: 2014-03-06 Release date: 2014-06-11 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Structural and functional characterization of human and murine C5a anaphylatoxins. Acta Crystallogr. D Biol. Crystallogr., 70, 2014
4DR1	Crystal structure of the apo 30S ribosomal subunit from Thermus thermophilus (HB8) Descriptor: 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... Authors: Demirci, H, Murphy IV, F, Murphy, E, Gregory, S.T, Dahlberg, A.E, Jogl, G. Deposit date: 2012-02-16 Release date: 2012-11-14 Last modified: 2013-01-30 Method: X-RAY DIFFRACTION (3.6 Å) Cite: A structural basis for streptomycin-induced misreading of the genetic code. Nat Commun, 4, 2013
4DV3	Crystal structure of the Thermus thermophilus 30S ribosomal subunit with a 16S rRNA mutation, C912A, bound with streptomycin Descriptor: 16S rRNA, MAGNESIUM ION, STREPTOMYCIN, ... Authors: Demirci, H, Murphy IV, F, Murphy, E, Gregory, S.T, Dahlberg, A.E, Jogl, G. Deposit date: 2012-02-22 Release date: 2013-02-27 Method: X-RAY DIFFRACTION (3.547 Å) Cite: A structural basis for streptomycin resistance To be Published
4POQ	Structure of unliganded VP1 pentamer of Human Polyomavirus 9 Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, ISOPROPYL ALCOHOL, ... Authors: Khan, Z.M, Stehle, T. Deposit date: 2014-02-26 Release date: 2014-04-09 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2 Å) Cite: Crystallographic and glycan microarray analysis of human polyomavirus 9 VP1 identifies N-glycolyl neuraminic acid as a receptor candidate. J.Virol., 88, 2014
4PV6	Crystal Structure Analysis of Ard1 from Thermoplasma volcanium Descriptor: ACETYL COENZYME *A, COENZYME A, N-terminal acetyltransferase complex subunit [ARD1] Authors: Ma, C, Lee, S.J, Lee, B.J. Deposit date: 2014-03-15 Release date: 2015-01-21 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (3.32 Å) Cite: Structure of Thermoplasma volcanium Ard1 belongs to N-acetyltransferase family member suggesting multiple ligand binding modes with acetyl coenzyme A and coenzyme A. Biochim.Biophys.Acta, 1844, 2014
4PJ1	Crystal structure of the human mitochondrial chaperonin symmetrical 'football' complex Descriptor: 10 kDa heat shock protein, mitochondrial, 60 kDa heat shock protein, ... Authors: Frolow, F, Azem, A, Nisemblat, S. Deposit date: 2014-05-10 Release date: 2015-04-29 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (3.15 Å) Cite: Crystal structure of the human mitochondrial chaperonin symmetrical football complex. Proc.Natl.Acad.Sci.USA, 112, 2015

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