6HW8
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![BU of 6hw8 by Molmil](/molmil-images/mine/6hw8) | Yeast 20S proteasome in complex with 39 | Descriptor: | (2~{S})-~{N}-[(3~{S},4~{R})-1-cyclohexyl-5-methyl-4,5-bis(oxidanyl)hexan-3-yl]-3-(4-methoxyphenyl)-2-[[(2~{S})-2-(2-morpholin-4-ylethanoylamino)propanoyl]amino]propanamide, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, ... | Authors: | Huber, E.M, Groll, M. | Deposit date: | 2018-10-11 | Release date: | 2019-01-30 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure-Based Design of Inhibitors Selective for Human Proteasome beta 2c or beta 2i Subunits. J.Med.Chem., 62, 2019
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6HWN
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![BU of 6hwn by Molmil](/molmil-images/mine/6hwn) | Structure of Thermus thermophilus ClpP in complex with a tripeptide. | Descriptor: | ATP-dependent Clp protease proteolytic subunit, DI(HYDROXYETHYL)ETHER, Unknown tripeptide | Authors: | Felix, J, Schanda, P, Fraga, H, Morlot, C. | Deposit date: | 2018-10-12 | Release date: | 2019-09-18 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Mechanism of the allosteric activation of the ClpP protease machinery by substrates and active-site inhibitors. Sci Adv, 5, 2019
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5TSX
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![BU of 5tsx by Molmil](/molmil-images/mine/5tsx) | |
5TRS
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![BU of 5trs by Molmil](/molmil-images/mine/5trs) | Structure of Mycobacterium tuberculosis proteasome in complex with N,C-capped dipeptide PKS2144 | Descriptor: | N-tert-butoxy-N~2~-(5-methyl-1,2-oxazole-3-carbonyl)-L-asparaginyl-O-methyl-N-[(naphthalen-1-yl)methyl]-L-serinamide, Proteasome subunit alpha, Proteasome subunit beta | Authors: | Hsu, H.-C, Fan, H, Singh, P.K, Wang, R, Sukenick, G, Nathan, C, Lin, G, Li, H. | Deposit date: | 2016-10-27 | Release date: | 2017-01-11 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (3.083567 Å) | Cite: | Structural Basis for the Species-Selective Binding of N,C-Capped Dipeptides to the Mycobacterium tuberculosis Proteasome. Biochemistry, 56, 2017
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6TDV
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6TF9
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![BU of 6tf9 by Molmil](/molmil-images/mine/6tf9) | Structure of the vertebrate gamma-Tubulin Ring Complex | Descriptor: | Actin, cytoplasmic 1, Belt helices 1,2,3,4, ... | Authors: | Zupa, E, Pfeffer, S. | Deposit date: | 2019-11-13 | Release date: | 2019-12-11 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (4.8 Å) | Cite: | Insights into the assembly and activation of the microtubule nucleator gamma-TuRC. Nature, 578, 2020
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6HCJ
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![BU of 6hcj by Molmil](/molmil-images/mine/6hcj) | Structure of the rabbit 80S ribosome on globin mRNA in the rotated state with A/P and P/E tRNAs | Descriptor: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ... | Authors: | Juszkiewicz, S, Chandrasekaran, V, Lin, Z, Kraatz, S, Ramakrishnan, V, Hegde, R.S. | Deposit date: | 2018-08-15 | Release date: | 2018-10-17 | Last modified: | 2018-11-14 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | ZNF598 Is a Quality Control Sensor of Collided Ribosomes. Mol. Cell, 72, 2018
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6HCQ
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![BU of 6hcq by Molmil](/molmil-images/mine/6hcq) | Structure of the rabbit collided di-ribosome (collided monosome) | Descriptor: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ... | Authors: | Juszkiewicz, S, Chandrasekaran, V, Lin, Z, Kraatz, S, Ramakrishnan, V, Hegde, R.S. | Deposit date: | 2018-08-16 | Release date: | 2018-10-17 | Last modified: | 2018-11-14 | Method: | ELECTRON MICROSCOPY (6.5 Å) | Cite: | ZNF598 Is a Quality Control Sensor of Collided Ribosomes. Mol. Cell, 72, 2018
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6HJD
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![BU of 6hjd by Molmil](/molmil-images/mine/6hjd) | Cholera toxin classical B-pentamer in complex with Lewis-x | Descriptor: | BICINE, CALCIUM ION, Cholera toxin B subunit, ... | Authors: | Krengel, U, Heim, J.B. | Deposit date: | 2018-09-03 | Release date: | 2019-08-14 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.54 Å) | Cite: | Crystal structures of cholera toxin in complex with fucosylated receptors point to importance of secondary binding site. Sci Rep, 9, 2019
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6TDU
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![BU of 6tdu by Molmil](/molmil-images/mine/6tdu) | Cryo-EM structure of Euglena gracilis mitochondrial ATP synthase, full dimer, rotational states 1 | Descriptor: | 2-(HEXADECANOYLOXY)-1-[(PHOSPHONOOXY)METHYL]ETHYL HEXADECANOATE, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ... | Authors: | Muhleip, A, Amunts, A. | Deposit date: | 2019-11-10 | Release date: | 2019-11-27 | Method: | ELECTRON MICROSCOPY (4.32 Å) | Cite: | Structure of a mitochondrial ATP synthase with bound native cardiolipin. Elife, 8, 2019
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5TW1
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![BU of 5tw1 by Molmil](/molmil-images/mine/5tw1) | Crystal structure of a Mycobacterium smegmatis transcription initiation complex with RbpA | Descriptor: | 1,2-ETHANEDIOL, DNA (26-MER), DNA (31-MER), ... | Authors: | Hubin, E.A, Darst, S.A, Campbell, E.A. | Deposit date: | 2016-11-10 | Release date: | 2017-01-18 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.76 Å) | Cite: | Structure and function of the mycobacterial transcription initiation complex with the essential regulator RbpA. Elife, 6, 2017
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6HK6
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![BU of 6hk6 by Molmil](/molmil-images/mine/6hk6) | Human RIOK2 bound to inhibitor | Descriptor: | 1,2-ETHANEDIOL, 2-naphthalen-2-yl-~{N}-pyridin-2-yl-ethanamide, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | Authors: | Wang, J, Krojer, T, Bountra, C, Edwards, A.M, Arrowsmith, C, Knapp, S, Elkins, J.M. | Deposit date: | 2018-09-05 | Release date: | 2018-10-24 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Crystal structure of human RIOK2 bound to a specific inhibitor. Open Biology, 9, 2019
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4ZK1
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![BU of 4zk1 by Molmil](/molmil-images/mine/4zk1) | Crystal Structure of Lymnaea stagnalis Acetylcholine-Binding Protein (LsAChBP) in Complex with 3-Pyrrolylmethylene Anabaseine | Descriptor: | (3E)-3-(1H-pyrrol-3-ylmethylidene)-3,4,5,6-tetrahydro-2,3'-bipyridine, Acetylcholine-binding protein, PHOSPHATE ION | Authors: | Bobango, J, Wu, J, Talley, T.T. | Deposit date: | 2015-04-29 | Release date: | 2015-05-13 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Crystal Structure of Lymnaea stagnalis Acetylcholine-Binding Protein (LsAChBP) in Complex with 3-Pyrrolylmethylene Anabaseine To be Published
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6TLK
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![BU of 6tlk by Molmil](/molmil-images/mine/6tlk) | Structure of methylene-tetrahydromethanopterin dehydrogenase from Methylorubrum extorquens AM1 in an open conformation containing NADP+ and methylene-H4MPT | Descriptor: | 5,10-DIMETHYLENE TETRAHYDROMETHANOPTERIN, Bifunctional protein MdtA, CHLORIDE ION, ... | Authors: | Wagner, T, Huang, G, Demmer, U, Warkentin, E, Ermler, U, Shima, S. | Deposit date: | 2019-12-02 | Release date: | 2020-02-26 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The Hydride Transfer Process in NADP-dependent Methylene-tetrahydromethanopterin Dehydrogenase. J.Mol.Biol., 432, 2020
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6TMK
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![BU of 6tmk by Molmil](/molmil-images/mine/6tmk) | Cryo-EM structure of Toxoplasma gondii mitochondrial ATP synthase dimer, composite model | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine, ADENOSINE-5'-DIPHOSPHATE, ... | Authors: | Muhleip, A, Kock Flygaard, R, Amunts, A. | Deposit date: | 2019-12-04 | Release date: | 2020-12-16 | Last modified: | 2021-01-20 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | ATP synthase hexamer assemblies shape cristae of Toxoplasma mitochondria. Nat Commun, 12, 2021
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6TSU
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![BU of 6tsu by Molmil](/molmil-images/mine/6tsu) | Capsid of empty GTA particle computed with C5 symmetry | Descriptor: | Major capsid protein Rcc01687, Uncharacterized protein | Authors: | Bardy, P, Fuzik, T, Hrebik, D, Pantucek, R, Beatty, J.T, Plevka, P. | Deposit date: | 2019-12-21 | Release date: | 2020-07-22 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.42 Å) | Cite: | Structure and mechanism of DNA delivery of a gene transfer agent. Nat Commun, 11, 2020
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5VPO
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![BU of 5vpo by Molmil](/molmil-images/mine/5vpo) | The 70S P-site ASL SufA6 complex | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | Authors: | Hong, S, Sunita, S, Dunkle, J.A, Maehigashi, T, Dunham, C.M. | Deposit date: | 2017-05-05 | Release date: | 2018-09-26 | Last modified: | 2018-11-07 | Method: | X-RAY DIFFRACTION (3.34 Å) | Cite: | Mechanism of tRNA-mediated +1 ribosomal frameshifting. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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7WUY
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![BU of 7wuy by Molmil](/molmil-images/mine/7wuy) | The crystal structure of FinI in complex with SAM and fischerin | Descriptor: | 1,2-ETHANEDIOL, 3-[[(1~{S},2~{R},4~{a}~{S},8~{a}~{S})-2-methyl-1,2,4~{a},5,6,7,8,8~{a}-octahydronaphthalen-1-yl]carbonyl]-5-[(1~{S},2~{R},5~{S},6~{S})-2,5-bis(oxidanyl)-7-oxabicyclo[4.1.0]heptan-2-yl]-4-oxidanyl-1~{H}-pyridin-2-one, DI(HYDROXYETHYL)ETHER, ... | Authors: | Zhou, J, Lu, J. | Deposit date: | 2022-02-09 | Release date: | 2023-02-15 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.84 Å) | Cite: | The crystal structure of FinI in complex with SAM and fischerin To Be Published
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6TB3
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![BU of 6tb3 by Molmil](/molmil-images/mine/6tb3) | yeast 80S ribosome in complex with the Not5 subunit of the CCR4-NOT complex | Descriptor: | 25S rRNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ... | Authors: | Buschauer, R, Cheng, J, Berninghausen, O, Tesina, P, Becker, T, Beckmann, R. | Deposit date: | 2019-10-31 | Release date: | 2020-04-22 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | The Ccr4-Not complex monitors the translating ribosome for codon optimality. Science, 368, 2020
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7WVS
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![BU of 7wvs by Molmil](/molmil-images/mine/7wvs) | The structure of FinI complex with SAM | Descriptor: | 1,2-ETHANEDIOL, GLYCEROL, Methyltransf_2 domain-containing protein, ... | Authors: | Lu, J, Zhou, J. | Deposit date: | 2022-02-11 | Release date: | 2023-02-15 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | The structure of FinI complex with SAM To Be Published
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6HTN
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![BU of 6htn by Molmil](/molmil-images/mine/6htn) | Structure of a fucose lectin from Kordia zhangzhouensis in complex with methyl-fucoside | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, 1,2-ETHANEDIOL, 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, ... | Authors: | Varrot, A. | Deposit date: | 2018-10-04 | Release date: | 2019-01-23 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Architecture and Evolution of Blade Assembly in beta-propeller Lectins. Structure, 27, 2019
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4Z3Z
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![BU of 4z3z by Molmil](/molmil-images/mine/4z3z) | Active site complex BamBC of Benzoyl Coenzyme A reductase in complex with Zinc | Descriptor: | Benzoyl-CoA reductase, putative, IRON/SULFUR CLUSTER, ... | Authors: | Weinert, T, Kung, J.W, Weidenweber, S, Huwiler, S.G, Boll, M, Ermler, U. | Deposit date: | 2015-04-01 | Release date: | 2015-06-24 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.666 Å) | Cite: | Structural basis of enzymatic benzene ring reduction. Nat.Chem.Biol., 11, 2015
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7WYI
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![BU of 7wyi by Molmil](/molmil-images/mine/7wyi) | Native Photosystem I of Chlamydomonas reinhardtii | Descriptor: | CHLOROPHYLL A, CHLOROPHYLL A ISOMER, CHLOROPHYLL B, ... | Authors: | Kurisu, G, Gerle, C, Mitsuoka, K, Kawamoto, A, Tanaka, H. | Deposit date: | 2022-02-16 | Release date: | 2023-02-22 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Three structures of PSI-LHCI from Chlamydomonas reinhardtii suggest a resting state re-activated by ferredoxin. Biochim Biophys Acta Bioenerg, 1864, 2023
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4Z77
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5VFS
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![BU of 5vfs by Molmil](/molmil-images/mine/5vfs) | Nucleotide-Driven Triple-State Remodeling of the AAA-ATPase Channel in the Activated Human 26S Proteasome | Descriptor: | 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, 26S proteasome non-ATPase regulatory subunit 12, ... | Authors: | Zhu, Y, Wang, W.L, Yu, D, Ouyang, Q, Lu, Y, Mao, Y. | Deposit date: | 2017-04-09 | Release date: | 2018-07-18 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structural mechanism for nucleotide-driven remodeling of the AAA-ATPase unfoldase in the activated human 26S proteasome. Nat Commun, 9, 2018
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