1PUU
| Mistletoe lectin I in complex with lactose | Descriptor: | 1,4-DIETHYLENE DIOXIDE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Krauspenhaar, R, Voelter, W, Stoeva, S, Mikhailov, A, Konareva, N, Betzel, C. | Deposit date: | 2003-06-25 | Release date: | 2004-06-25 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Mistletoe lectin I in complex with galactose and lactose reveals distinct sugar-binding properties Acta Crystallogr.,Sect.F, 61, 2005
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1RMY
| Crystal structure of AphA class B acid phosphatase/phosphotransferase ternary complex with deoxycytosine and phosphate bound to the catalytic metal | Descriptor: | 2'-DEOXYCYTIDINE, Class B acid phosphatase, MAGNESIUM ION, ... | Authors: | Calderone, V, Forleo, C, Benvenuti, M, Rossolini, G.M, Thaller, M.C, Mangani, S. | Deposit date: | 2003-11-28 | Release date: | 2004-12-14 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Insights in the catalytic mechanism of AphA from Escherichia coli To be Published
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1QYV
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3LQ0
| Zymogen structure of crayfish astacin metallopeptidase | Descriptor: | GLYCEROL, ProAstacin, SULFATE ION, ... | Authors: | Guevara, T, Yiallouros, I, Kappelhoff, R, Bissdorf, S, Stocker, W, Gomis-Ruth, F.X. | Deposit date: | 2010-02-08 | Release date: | 2010-02-23 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Proenzyme structure and activation of astacin metallopeptidase J.Biol.Chem., 285, 2010
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1RH1
| crystal structure of the cytotoxic bacterial protein colicin B at 2.5 A resolution | Descriptor: | Colicin B | Authors: | Hilsenbeck, J.L, Park, H, Chen, G, Youn, B, Postle, K, Kang, C. | Deposit date: | 2003-11-13 | Release date: | 2004-03-09 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of the cytotoxic bacterial protein colicin B at 2.5 A resolution Mol.Microbiol., 51, 2004
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1UJ6
| Crystal structure of Thermus thermophilus ribose-5-phosphate isomerase complexed with arabinose-5-phosphate | Descriptor: | ARABINOSE-5-PHOSPHATE, CHLORIDE ION, ribose 5-phosphate isomerase | Authors: | Hamada, K, Ago, H, Sugahara, M, Nodake, Y, Kuramitsu, S, Yokoyama, S, Miyano, M, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2003-07-26 | Release date: | 2004-07-13 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.74 Å) | Cite: | Oxyanion hole-stabilized stereospecific isomerization in ribose-5-phosphate isomerase (Rpi) J.Biol.Chem., 278, 2003
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1WN4
| NMR Structure of VoNTR | Descriptor: | VoNTR protein | Authors: | Dutton, J.L, Renda, R.F, Waine, C, Clark, R.J, Daly, N.L, Jennings, C.V, Anderson, M.A, Craik, D.J. | Deposit date: | 2004-07-27 | Release date: | 2004-09-14 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Conserved structural and sequence elements implicated in the processing of gene-encoded circular proteins J.Biol.Chem., 279, 2004
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1WN8
| NMR Structure of OaNTR | Descriptor: | Kalata B3/B6 | Authors: | Dutton, J.L, Renda, R.F, Waine, C, Clark, R.J, Daly, N.L, Jennings, C.V, Anderson, M.A, Craik, D.J. | Deposit date: | 2004-07-28 | Release date: | 2004-09-14 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Conserved structural and sequence elements implicated in the processing of gene-encoded circular proteins J.Biol.Chem., 279, 2004
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8PD4
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4P60
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4P73
| PheRS in complex with compound 1a | Descriptor: | 1-{3-[(4-pyridin-2-ylpiperazin-1-yl)sulfonyl]phenyl}-3-(1,3-thiazol-2-yl)urea, Phenylalanine--tRNA ligase alpha subunit, Phenylalanine--tRNA ligase beta subunit | Authors: | Ferguson, A.D. | Deposit date: | 2014-03-25 | Release date: | 2014-06-25 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (3.03 Å) | Cite: | The role of a novel auxiliary pocket in bacterial phenylalanyl-tRNA synthetase druggability. J.Biol.Chem., 289, 2014
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4PBE
| Phosphotriesterase Variant Rev6 | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, CACODYLATE ION, Phosphotriesterase variant PTE-revR6, ... | Authors: | Campbell, E, Kaltenbach, M, Tokuriki, N, Jackson, C.J. | Deposit date: | 2014-04-12 | Release date: | 2015-05-06 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.51 Å) | Cite: | The role of protein dynamics in the evolution of new enzyme function. Nat. Chem. Biol., 12, 2016
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2W99
| Crystal Structure of CDK4 in complex with a D-type cyclin | Descriptor: | CELL DIVISION PROTEIN KINASE 4, G1/S-SPECIFIC CYCLIN-D1 | Authors: | Day, P.J, Cleasby, A, Tickle, I.J, Reilly, M.O, Coyle, J.E, Holding, F.P, McMenamin, R.L, Yon, J, Chopra, R, Lengauer, C, Jhoti, H. | Deposit date: | 2009-01-22 | Release date: | 2009-03-10 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal Structure of Human Cdk4 in Complex with a D-Type Cyclin. Proc.Natl.Acad.Sci.USA, 106, 2009
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1JK2
| Zif268 D20A mutant bound to the GCT DNA site | Descriptor: | 5'-D(*AP*GP*CP*GP*TP*GP*GP*GP*CP*TP*G)-3', 5'-D(*TP*CP*AP*GP*CP*CP*CP*AP*CP*GP*C)-3', ZIF268, ... | Authors: | Miller, J.C, Pabo, C.O. | Deposit date: | 2001-07-11 | Release date: | 2001-10-19 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Rearrangement of side-chains in a Zif268 mutant highlights the complexities of zinc finger-DNA recognition. J.Mol.Biol., 313, 2001
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4PMO
| Crystal structure of the Mycobacterium tuberculosis Tat-secreted protein Rv2525c, monoclinic crystal form I | Descriptor: | FORMIC ACID, GLYCEROL, SODIUM ION, ... | Authors: | Bellinzoni, M, Haouz, A, Shepard, W, Alzari, P.M. | Deposit date: | 2014-05-22 | Release date: | 2014-10-08 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.33 Å) | Cite: | Structural studies suggest a peptidoglycan hydrolase function for the Mycobacterium tuberculosis Tat-secreted protein Rv2525c. J.Struct.Biol., 188, 2014
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4PN8
| A de novo designed pentameric coiled coil CC-Pent. | Descriptor: | CC-Pent | Authors: | Wood, C.W, Burton, A.J, Thomson, A.R, Brady, R.L, Woolfson, D.N. | Deposit date: | 2014-05-23 | Release date: | 2014-10-22 | Last modified: | 2017-09-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Computational design of water-soluble alpha-helical barrels. Science, 346, 2014
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4PCS
| Crystal structure of a bacterial fucosidase with iminosugar (2S,3S,4R,5S)-3,4-dihydroxy-2-[2'-phenyl]ethynyl-5-methylpyrrolidine | Descriptor: | (2S,3R,4S,5S)-2-methyl-5-(phenylethynyl)pyrrolidine-3,4-diol, Alpha-L-fucosidase, IMIDAZOLE, ... | Authors: | Davies, G.J, Wright, D.W, Behr, J.B. | Deposit date: | 2014-04-16 | Release date: | 2014-07-09 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.77 Å) | Cite: | Exploiting the Hydrophobic Terrain in Fucosidases with Aryl-Substituted Pyrrolidine Iminosugars. Chembiochem, 16, 2015
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4PHM
| The Structural Basis of Differential Inhibition of Human Calpain by Indole and Phenyl alpha-Mercaptoacrylic Acids | Descriptor: | 3-(5-bromo-1H-indol-3-yl)-2-thioxopropanoic acid, CALCIUM ION, Calpain small subunit 1 | Authors: | Rizkallah, P.J, Allemann, R.K, Adams, S.E, Miller, D.J, Hallett, M.B. | Deposit date: | 2014-05-06 | Release date: | 2014-08-13 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.03 Å) | Cite: | The structural basis of differential inhibition of human calpain by indole and phenyl alpha-mercaptoacrylic acids. J.Struct.Biol., 187, 2014
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4PFR
| CRYSTAL STRUCTURE OF A TRAP PERIPLASMIC SOLUTE BINDING PROTEIN FROM RHODOBACTER SPHAEROIDES (Rsph17029_3541, TARGET EFI-510203), APO OPEN PARTIALLY DISORDERED | Descriptor: | D-MALATE, TRAP dicarboxylate transporter, DctP subunit | Authors: | Vetting, M.W, Al Obaidi, N.F, Morisco, L.L, Wasserman, S.R, Stead, M, Attonito, J.D, Scott Glenn, A, Chowdhury, S, Evans, B, Hillerich, B, Love, J, Seidel, R.D, Whalen, K.L, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) | Deposit date: | 2014-04-30 | Release date: | 2014-05-14 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Experimental strategies for functional annotation and metabolism discovery: targeted screening of solute binding proteins and unbiased panning of metabolomes. Biochemistry, 54, 2015
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4P75
| PheRS in complex with compound 4a | Descriptor: | 3-(3-methoxyphenyl)-5-(trifluoromethyl)-1H-pyrazole, Phenylalanine--tRNA ligase alpha subunit, Phenylalanine--tRNA ligase beta subunit | Authors: | Ferguson, A.D. | Deposit date: | 2014-03-25 | Release date: | 2014-06-25 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.96 Å) | Cite: | The role of a novel auxiliary pocket in bacterial phenylalanyl-tRNA synthetase druggability. J.Biol.Chem., 289, 2014
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4P81
| Structure of ancestral PyrR protein (AncORANGEPyrR) | Descriptor: | Ancestral PyrR protein (Orange), GLYCEROL, SULFATE ION | Authors: | Perica, T, Kondo, Y, Tiwari, S, McLaughlin, S, Steward, A, Reuter, N, Clarke, J, Teichmann, S.A. | Deposit date: | 2014-03-29 | Release date: | 2014-12-17 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Evolution of oligomeric state through allosteric pathways that mimic ligand binding. Science, 346, 2014
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4PBF
| Phosphotriesterase variant Rev12 | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, CACODYLATE ION, Phosphotriesterase variant PTE-revR12, ... | Authors: | Campbell, E, Kaltenbach, M, Tokuriki, N, Jackson, C.J. | Deposit date: | 2014-04-12 | Release date: | 2015-05-06 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The role of protein dynamics in the evolution of new enzyme function. Nat. Chem. Biol., 12, 2016
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4PBZ
| Structure of the human RbAp48-MTA1(670-695) complex | Descriptor: | Histone-binding protein RBBP4, Metastasis-associated protein MTA1 | Authors: | Murthy, A, Pei, X.Y, Watson, A.A, Silva, A.P.G, Mackay, J.P, Laue, E.D. | Deposit date: | 2014-04-14 | Release date: | 2014-06-11 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Insight into the architecture of the NuRD complex: Structure of the RbAp48-MTA1 sub-complex. J.Biol.Chem., 289, 2014
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4PCN
| Phosphotriesterase variant R22 | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, Phosphotriesterase variant PTE-R22, ZINC ION | Authors: | Jackson, C.J, Campbell, E, Kaltenbach, M, Tokuriki, N. | Deposit date: | 2014-04-16 | Release date: | 2015-05-06 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.54 Å) | Cite: | The role of protein dynamics in the evolution of new enzyme function. Nat. Chem. Biol., 12, 2016
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4PA8
| Crystal structure of a de novo retro-aldolase catalyzing asymmetric Michael additions, with a covalently bound product analog | Descriptor: | (3R)-3-(4-methoxyphenyl)-5-oxohexanenitrile, GLYCEROL, SULFATE ION, ... | Authors: | Beck, T, Garrabou Pi, X, Hilvert, D. | Deposit date: | 2014-04-07 | Release date: | 2015-04-01 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | A Promiscuous De Novo Retro-Aldolase Catalyzes Asymmetric Michael Additions via Schiff Base Intermediates. Angew.Chem.Int.Ed.Engl., 54, 2015
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