4YU0
| Crystal structure of a tetramer of GluA2 TR mutant ligand binding domains bound with glutamate at 1.26 Angstrom resolution | Descriptor: | DI(HYDROXYETHYL)ETHER, GLUTAMIC ACID, Glutamate receptor 2,Glutamate receptor 2, ... | Authors: | Chebli, M, Salazar, H, Baranovic, J, Carbone, A.L, Ghisi, V, Faelber, K, Lau, A.Y, Daumke, O, Plested, A.J.R. | Deposit date: | 2015-03-18 | Release date: | 2016-01-13 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.26 Å) | Cite: | Crystal structure of the tetrameric GluA2 ligand-binding domain in complex with glutamate at 1.26 Angstroms resolution To Be Published
|
|
5E6O
| Crystal structure of C. elegans LGG-2 bound to an AIM/LIR motif | Descriptor: | Protein lgg-2, TRP-GLU-GLU-LEU | Authors: | Qi, X, Ren, J.Q, Wu, F, Zhang, H, Feng, W. | Deposit date: | 2015-10-10 | Release date: | 2016-01-06 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural Basis of the Differential Function of the Two C. elegans Atg8 Homologs, LGG-1 and LGG-2, in Autophagy Mol.Cell, 60, 2015
|
|
6BH8
| Crystal structure of ZMPSTE24 in complex with phosphoramidon | Descriptor: | (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, CAAX prenyl protease 1 homolog, N-ALPHA-L-RHAMNOPYRANOSYLOXY(HYDROXYPHOSPHINYL)-L-LEUCYL-L-TRYPTOPHAN, ... | Authors: | Goblirsch, B.R, Arachea, B.T, Wiener, M.C. | Deposit date: | 2017-10-30 | Release date: | 2018-08-15 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (3.85 Å) | Cite: | Phosphoramidon inhibits the integral membrane protein zinc metalloprotease ZMPSTE24. Acta Crystallogr D Struct Biol, 74, 2018
|
|
2VA5
| X-ray crystal structure of beta secretase complexed with compound 8c | Descriptor: | 2-amino-6-[2-(1H-indol-6-yl)ethyl]pyrimidin-4(3H)-one, BETA-SECRETASE 1 ., IODIDE ION | Authors: | Edwards, P.D, Albert, J.S, Sylvester, M, Aharony, D, Andisik, D, Callaghan, O, Campbell, J.B, Carr, R.A, Chessari, G, Congreve, M, Frederickson, M, Folmer, R.H.A, Geschwindner, S, Koether, G, Kolmodin, K, Krumrine, J, Mauger, R.C, Murray, C.W, Olsson, L, Patel, S, Spear, N, Tian, G. | Deposit date: | 2007-08-30 | Release date: | 2007-11-13 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Application of Fragment-Based Lead Generation to the Discovery of Novel, Cyclic Amidine Beta-Secretase Inhibitors with Nanomolar Potency, Cellular Activity, and High Ligand Efficiency. J.Med.Chem., 50, 2007
|
|
2V1P
| Crystal Structure of the apo form of Y74F mutant E. coli tryptophanase | Descriptor: | CHLORIDE ION, MAGNESIUM ION, TRYPTHOPANASE | Authors: | Kogan, A, Gdalevsky, G.Y, Cohen-Luria, R, Goldgur, Y, Parola, A.H, Almog, O. | Deposit date: | 2007-05-28 | Release date: | 2008-06-10 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Conformational Changes and Loose Packing Promote E. Coli Tryptophanase Cold Lability. Bmc Struct.Biol., 9, 2009
|
|
1K9A
| Crystal structure analysis of full-length carboxyl-terminal Src kinase at 2.5 A resolution | Descriptor: | Carboxyl-terminal Src kinase | Authors: | Ogawa, A, Takayama, Y, Nagata, A, Chong, K.T, Takeuchi, S, Sakai, H, Nakagawa, A, Nada, S, Okada, M, Tsukihara, T. | Deposit date: | 2001-10-28 | Release date: | 2002-03-20 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structure of the carboxyl-terminal Src kinase, Csk. J.Biol.Chem., 277, 2002
|
|
2CG6
| Second and third fibronectin type I module pair (crystal form I). | Descriptor: | HUMAN FIBRONECTIN, SULFATE ION | Authors: | Rudino-Pinera, E, Ravelli, R.B.G, Sheldrick, G.M, Nanao, M.H, Werner, J.M, Schwarz-Linek, U, Potts, J.R, Garman, E.F. | Deposit date: | 2006-02-27 | Release date: | 2007-02-27 | Last modified: | 2017-08-30 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | The Solution and Crystal Structures of a Module Pair from the Staphylococcus Aureus-Binding Site of Human Fibronectin-A Tale with a Twist. J.Mol.Biol., 368, 2007
|
|
4HH8
| Crystal structure of bovine butyrophilin | Descriptor: | Butyrophilin subfamily 1 member A1 | Authors: | Eichinger, A, Skerra, A. | Deposit date: | 2012-10-09 | Release date: | 2013-11-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | The extracellular region of bovine butyrophilin exhibits high structural similarity to human myelin oligodendrocyte glycoprotein To be Published
|
|
1K9T
| Chitinase a complexed with tetra-N-acetylchitotriose | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHITINASE A | Authors: | Prag, G, Tucker, P.A, Oppenheim, A.B. | Deposit date: | 2001-10-30 | Release date: | 2002-11-06 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Complex Structures of Chitinase A Mutant with Oligonag Provide Insight Into the Enzymatic Mechanism To be Published
|
|
6BQL
| Crystal Structure of the Human CAMKK2B in complex with TAE-226 | Descriptor: | 1,2-ETHANEDIOL, 2-({5-CHLORO-2-[(2-METHOXY-4-MORPHOLIN-4-YLPHENYL)AMINO]PYRIMIDIN-4-YL}AMINO)-N-METHYLBENZAMIDE, ACETATE ION, ... | Authors: | Counago, R.M, de Souza, G.P, dos Reis, C.V, Ramos, P.Z, Drewry, D, Massirer, K.B, Arruda, P, Edwards, A.M, Elkins, J.M, Structural Genomics Consortium (SGC) | Deposit date: | 2017-11-28 | Release date: | 2017-12-13 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal Structure of the Human CAMKK2B in complex with TAE-226 To Be Published
|
|
3F19
| |
1KBU
| CRE RECOMBINASE BOUND TO A LOXP HOLLIDAY JUNCTION | Descriptor: | CRE RECOMBINASE, LOXP | Authors: | Martin, S.S, Pulido, E, Chu, V.C, Lechner, T, Baldwin, E.P. | Deposit date: | 2001-11-06 | Release date: | 2002-06-07 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | The Order of Strand Exchanges in Cre-LoxP Recombination and its Basis Suggested by the Crystal Structure of a
Cre-LoxP Holliday Junction Complex J.Mol.Biol., 319, 2002
|
|
5DPE
| Thermolysin in complex with inhibitor. | Descriptor: | CALCIUM ION, DIMETHYL SULFOXIDE, GLYCEROL, ... | Authors: | Krimmer, S.G, Heine, A, Klebe, G. | Deposit date: | 2015-09-12 | Release date: | 2015-10-28 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.34 Å) | Cite: | Thermodynamics of protein-ligand interactions as a reference for computational analysis: how to assess accuracy, reliability and relevance of experimental data. J. Comput. Aided Mol. Des., 29, 2015
|
|
4GQH
| The Conformations and Interactions of the Four-Layer Aggregate Revealed by X-ray Crystallography Diffraction Implied the Importance of Peptides at Opposite Ends in Their Assemblies | Descriptor: | Capsid protein | Authors: | Li, X.Y, Song, B.A, Hu, D.Y, Chen, X, Wang, Z.C, Zeng, M.J, Yu, D.D, Chen, Z, Jin, L.H, Yang, S. | Deposit date: | 2012-08-23 | Release date: | 2013-08-28 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (3.06 Å) | Cite: | The Conformations and Interactions of the Four-Layer Aggregate Revealed by X-ray Crystallography Diffraction Implied the Importance of Peptides at Opposite Ends in Their Assemblies To be Published
|
|
4YAX
| Crystal structure of TRIM24 PHD-bromodomain complexed with N-[6-(4-methoxyphenoxy)-1,3-dimethyl-2-oxo-2,3-dihydro-1H-1,3-benzodiazol-5-yl]benzenesulfonamide (5g) | Descriptor: | GLYCEROL, N-[6-(4-methoxyphenoxy)-1,3-dimethyl-2-oxo-2,3-dihydro-1H-benzimidazol-5-yl]benzenesulfonamide, SULFATE ION, ... | Authors: | Poncet-Montange, G, Palmer, W, Jones, P. | Deposit date: | 2015-02-18 | Release date: | 2015-06-24 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Structure-Guided Design of IACS-9571, a Selective High-Affinity Dual TRIM24-BRPF1 Bromodomain Inhibitor. J.Med.Chem., 59, 2016
|
|
5DPX
| 1,2,4-Triazole-3-thione compounds as inhibitors of L1, di-zinc metallo-beta-lactamases. | Descriptor: | 5-(2-methylphenyl)-3H-1,2,4-triazole-3-thione, Metallo-beta-lactamase L1 type 3, SULFATE ION, ... | Authors: | Nauton, L, Garau, G, Khan, R, Dideberg, O. | Deposit date: | 2015-09-14 | Release date: | 2017-01-11 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | 1,2,4-Triazole-3-thione Compounds as Inhibitors of Dizinc Metallo-beta-lactamases. ChemMedChem, 12, 2017
|
|
2WJU
| |
5DQM
| Green/cyan WasCFP at pH 2.0 | Descriptor: | WasCFP_pH2 | Authors: | Pletnev, V.Z, Pletneva, N.V, Pletnev, S.V. | Deposit date: | 2015-09-14 | Release date: | 2016-07-27 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Crystal structure of pH and T dependent green fluorescent protein WasCFP with Trp based chromophore Russ.J.Bioorganic Chem., 42 (6), 2016
|
|
4YC7
| |
5DR1
| |
4GU8
| Crystal Structure of Burkholderia oklahomensis agglutinin (BOA) | Descriptor: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, Burkholderia oklahomensis agglutinin (BOA), GLYCEROL | Authors: | Whitley, M.J, Furey, W, Gronenborn, A.M. | Deposit date: | 2012-08-29 | Release date: | 2013-05-08 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Burkholderia oklahomensis agglutinin is a canonical two-domain OAA-family lectin: structures, carbohydrate binding and anti-HIV activity. Febs J., 280, 2013
|
|
2CTT
| Solution structure of zinc finger domain from human DnaJ subfamily A menber 3 | Descriptor: | DnaJ homolog subfamily A member 3, ZINC ION | Authors: | Kobayashi, N, Tochio, N, Saito, K, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2005-05-24 | Release date: | 2005-11-24 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of zinc finger domain from human DnaJ subfamily A menber 3 To be Published
|
|
2WIO
| Structure of the histidine tagged, open cytochrome P450 Eryk from S. erythraea | Descriptor: | ERYTHROMYCIN B/D C-12 HYDROXYLASE, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Savino, C, Montemiglio, L.C, Sciara, G, Miele, A.E, Kedrew, S.G, Gianni, S, Vallone, B. | Deposit date: | 2009-05-14 | Release date: | 2009-07-21 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Investigating the Structural Plasticity of a Cytochrome P450: Three-Dimensional Structures of P450 Eryk and Binding to its Physiological Substrate. J.Biol.Chem., 284, 2009
|
|
3F36
| Apoferritin: complex with 2-isopropylphenol | Descriptor: | 2-(1-methylethyl)phenol, CADMIUM ION, Ferritin light chain, ... | Authors: | Vedula, L.S, Economou, N.J, Rossi, M.J, Eckenhoff, R.G, Loll, P.J. | Deposit date: | 2008-10-30 | Release date: | 2009-07-14 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | A unitary anesthetic binding site at high resolution. J.Biol.Chem., 284, 2009
|
|
2WM4
| X-ray structure of Mycobacterium tuberculosis cytochrome P450 CYP124 in complex with phytanic acid | Descriptor: | (3R,7S,11S)-3,7,11,15-tetramethylhexadecanoic acid, CALCIUM ION, PROTOPORPHYRIN IX CONTAINING FE, ... | Authors: | Johnston, J.B, Kells, P.M, Podust, L.M, Ortiz de Montellano, P.R. | Deposit date: | 2009-06-30 | Release date: | 2009-10-06 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.11 Å) | Cite: | Biochemical and structural characterization of CYP124: a methyl-branched lipid omega-hydroxylase from Mycobacterium tuberculosis. Proc. Natl. Acad. Sci. U.S.A., 106, 2009
|
|