7ZIT
| 14-3-3 in complex with SARS-COV2 N phospho-peptide | Descriptor: | 14-3-3 protein zeta/delta, ACETATE ION, BENZOIC ACID, ... | Authors: | Eisenreichova, A, Boura, E. | Deposit date: | 2022-04-08 | Release date: | 2022-10-26 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | Structural basis for SARS-CoV-2 nucleocapsid (N) protein recognition by 14-3-3 proteins. J.Struct.Biol., 214, 2022
|
|
1FFQ
| CRYSTAL STRUCTURE OF CHITINASE A COMPLEXED WITH ALLOSAMIDIN | Descriptor: | 2-acetamido-2-deoxy-beta-D-allopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-allopyranose, ALLOSAMIZOLINE, CHITINASE A | Authors: | Papanikolau, Y, Tavlas, G, Vorgias, C.E, Petratos, K. | Deposit date: | 2000-07-26 | Release date: | 2003-02-11 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | De novo purification scheme and crystallization conditions yield high-resolution structures of chitinase A and its complex with the inhibitor allosamidin. Acta Crystallogr.,Sect.D, 59, 2003
|
|
1FGT
| |
1WCI
| Reactivity modulation of human branched-chain alpha-ketoacid dehydrogenase by an internal molecular switch | Descriptor: | 2-OXOISOVALERATE DEHYDROGENASE ALPHA SUBUNIT, 2-OXOISOVALERATE DEHYDROGENASE BETA SUBUNIT, C2-1-HYDROXY-3-METHYL-BUTYL-THIAMIN, ... | Authors: | Machius, M, Wynn, R.M, Chuang, J.L, Tomchick, D.R, Brautigam, C.A, Chuang, D.T. | Deposit date: | 2004-11-16 | Release date: | 2006-02-16 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.84 Å) | Cite: | A Versatile Conformational Switch Regulates Reactivity in Human Branched-Chain Alpha-Ketoacid Dehydrogenase. Structure, 14, 2006
|
|
3Q14
| Toluene 4 monooxygenase HD Complex with p-cresol | Descriptor: | FE (III) ION, P-CRESOL, PENTAETHYLENE GLYCOL, ... | Authors: | Acheson, J.F, Bailey, L.J, Fox, B.G. | Deposit date: | 2010-12-16 | Release date: | 2011-12-21 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Crystallographic analysis of active site contributions to regiospecificity in the diiron enzyme toluene 4-monooxygenase. Biochemistry, 51, 2012
|
|
1R00
| Crystal structure of aclacinomycin-10-hydroxylase (RdmB) in complex with S-adenosyl-L-homocysteine (SAH) | Descriptor: | ACETATE ION, S-ADENOSYL-L-HOMOCYSTEINE, aclacinomycin-10-hydroxylase | Authors: | Jansson, A, Niemi, J, Lindqvist, Y, Mantsala, P, Schneider, G. | Deposit date: | 2003-09-19 | Release date: | 2003-11-25 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal Structure of Aclacinomycin-10-Hydroxylase, a S-Adenosyl-L-Methionine-dependent Methyltransferase Homolog Involved in Anthracycline Biosynthesis in Streptomyces purpurascens. J.Mol.Biol., 334, 2003
|
|
1DHK
| STRUCTURE OF PORCINE PANCREATIC ALPHA-AMYLASE | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BEAN LECTIN-LIKE INHIBITOR, ... | Authors: | Bompard-Gilles, C, Payan, F. | Deposit date: | 1996-10-14 | Release date: | 1997-12-24 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Substrate mimicry in the active center of a mammalian alpha-amylase: structural analysis of an enzyme-inhibitor complex. Structure, 4, 1996
|
|
3CB0
| CobR | Descriptor: | 4-HYDROXYPHENYLACETATE 3-MONOOXYGENASE, FLAVIN MONONUCLEOTIDE | Authors: | Lawrence, A.D, Warren, M.J, Pickersgill, R.W. | Deposit date: | 2008-02-21 | Release date: | 2008-03-11 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Identification, characterization, and structure/function analysis of a corrin reductase involved in adenosylcobalamin biosynthesis J.Biol.Chem., 283, 2008
|
|
4B3B
| Humanised monomeric RadA in complex with FHTA tetrapeptide | Descriptor: | DNA REPAIR AND RECOMBINATION PROTEIN RADA, FHTA TETRAPEPTIDE, PHOSPHATE ION | Authors: | Scott, D.E, Ehebauer, M.T, Pukala, T, Marsh, M, Blundell, T.L, Venkitaraman, A.R, Abell, C, Hyvonen, M. | Deposit date: | 2012-07-23 | Release date: | 2013-02-27 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.193 Å) | Cite: | Using a Fragment-Based Approach to Target Protein-Protein Interactions. Chembiochem, 14, 2013
|
|
1WDL
| fatty acid beta-oxidation multienzyme complex from Pseudomonas fragi, form II (native4) | Descriptor: | 3,6,9,12,15-PENTAOXATRICOSAN-1-OL, 3-ketoacyl-CoA thiolase, ACETYL COENZYME *A, ... | Authors: | Ishikawa, M, Tsuchiya, D, Oyama, T, Tsunaka, Y, Morikawa, K. | Deposit date: | 2004-05-17 | Release date: | 2004-07-27 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Structural basis for channelling mechanism of a fatty acid beta-oxidation multienzyme complex Embo J., 23, 2004
|
|
3CCW
| Thermodynamic and structure guided design of statin hmg-coa reductase inhibitors | Descriptor: | (3R,5R)-7-[4-(benzylcarbamoyl)-2-(4-fluorophenyl)-5-(1-methylethyl)-1H-imidazol-1-yl]-3,5-dihydroxyheptanoic acid, 3-hydroxy-3-methylglutaryl-coenzyme A reductase | Authors: | Pavlovsky, A, Sarver, R.W, Harris, M.S, Finzel, B.C. | Deposit date: | 2008-02-26 | Release date: | 2008-06-17 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Thermodynamic and structure guided design of statin based inhibitors of 3-hydroxy-3-methylglutaryl coenzyme a reductase. J.Med.Chem., 51, 2008
|
|
1DIL
| SIALIDASE FROM SALMONELLA TYPHIMURIUM COMPLEXED WITH APANA AND EPANA INHIBITORS | Descriptor: | (1R)-4-acetamido-1,5-anhydro-2,4-dideoxy-1-phosphono-D-glycero-D-galacto-octitol, (1S)-4-acetamido-1,5-anhydro-2,4-dideoxy-1-phosphono-D-glycero-D-galacto-octitol, POTASSIUM ION, ... | Authors: | Garman, E.F, Crennell, S.C, Vimr, E.R, Laver, W.G, Taylor, G.L. | Deposit date: | 1996-04-23 | Release date: | 1996-12-07 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The structures of Salmonella typhimurium LT2 neuraminidase and its complexes with three inhibitors at high resolution. J.Mol.Biol., 259, 1996
|
|
1DOR
| DIHYDROOROTATE DEHYDROGENASE A FROM LACTOCOCCUS LACTIS | Descriptor: | DIHYDROOROTATE DEHYDROGENASE A, FLAVIN MONONUCLEOTIDE | Authors: | Rowland, P, Larsen, S. | Deposit date: | 1997-01-14 | Release date: | 1997-04-21 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The crystal structure of the flavin containing enzyme dihydroorotate dehydrogenase A from Lactococcus lactis. Structure, 5, 1997
|
|
3CDR
| R96Q Mutant of wildtype phage T4 lysozyme at 298 K | Descriptor: | 2-HYDROXYETHYL DISULFIDE, CHLORIDE ION, Lysozyme | Authors: | Mooers, B.H.M. | Deposit date: | 2008-02-27 | Release date: | 2009-02-17 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Contributions of all 20 amino acids at site 96 to the stability and structure of T4 lysozyme. Protein Sci., 18, 2009
|
|
3OGS
| Complex structure of beta-galactosidase from Trichoderma reesei with IPTG | Descriptor: | 1-methylethyl 1-thio-beta-D-galactopyranoside, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Maksimainen, M, Rouvinen, J. | Deposit date: | 2010-08-17 | Release date: | 2011-03-16 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Crystal structures of Trichoderma reesei beta-galactosidase reveal conformational changes in the active site J.Struct.Biol., 174, 2011
|
|
1IEQ
| CRYSTAL STRUCTURE OF BARLEY BETA-D-GLUCAN GLUCOHYDROLASE ISOENZYME EXO1 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)]2-acetamido-2-deoxy-beta-D-glucopyranose, BETA-D-GLUCAN GLUCOHYDROLASE ISOENZYME EXO1, beta-D-glucopyranose, ... | Authors: | Hrmova, M, DeGori, R, Fincher, G.B, Varghese, J.N. | Deposit date: | 2001-04-11 | Release date: | 2001-11-14 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Catalytic mechanisms and reaction intermediates along the hydrolytic pathway of a plant beta-D-glucan glucohydrolase. Structure, 9, 2001
|
|
4B7U
| |
1DOD
| THE MOBIL FLAVIN OF 4-OH BENZOATE HYDROXYLASE: MOTION OF A PROSTHETIC GROUP REGULATES CATALYSIS | Descriptor: | 2,4-DIHYDROXYBENZOIC ACID, FLAVIN-ADENINE DINUCLEOTIDE, P-HYDROXYBENZOATE HYDROXYLASE | Authors: | Gatti, D.L, Palfey, B.A, Lah, M.S, Entsch, B, Massey, V, Ballou, D.P, Ludwig, M.L. | Deposit date: | 1994-09-06 | Release date: | 1994-11-30 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The mobile flavin of 4-OH benzoate hydroxylase. Science, 266, 1994
|
|
2Z29
| Thr109Ala dihydroorotase from E. coli | Descriptor: | (4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, Dihydroorotase, N-CARBAMOYL-L-ASPARTATE, ... | Authors: | Lee, M, Maher, M.J, Guss, J.M. | Deposit date: | 2007-05-17 | Release date: | 2007-10-09 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Kinetic and Structural Analysis of Mutant Escherichia coli Dihydroorotases: A Flexible Loop Stabilizes the Transition State Biochemistry, 46, 2007
|
|
1IGO
| Family 11 xylanase | Descriptor: | SULFATE ION, family 11 xylanase | Authors: | Oakley, A.J, Thomson, C, Heinrich, T, Dunlop, R, Wilce, M.C.J. | Deposit date: | 2001-04-18 | Release date: | 2002-04-18 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Characterization of a family 11 xylanase from Bacillus subtillis B230 used for paper bleaching. Acta Crystallogr.,Sect.D, 59, 2003
|
|
8A4C
| Structure of human Rep15:Rab3B complex. | Descriptor: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Rab15 effector protein, ... | Authors: | Rai, A, Vetter, I.R, Goody, R.S. | Deposit date: | 2022-06-10 | Release date: | 2022-08-10 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Rep15 interacts with several Rab GTPases and has a distinct fold for a Rab effector. Nat Commun, 13, 2022
|
|
1IO9
| THERMOPHILIC CYTOCHROME P450 (CYP119) FROM SULFOLOBUS SOLFATARICUS: HIGH RESOLUTION STRUCTURAL ORIGIN OF ITS THERMOSTABILITY AND FUNCTIONAL PROPERTIES | Descriptor: | CYTOCHROME P450 CYP119, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Park, S.-Y, Yamane, K, Adachi, S, Shiro, Y, Sligar, S.G, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2001-02-08 | Release date: | 2001-03-07 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Thermophilic cytochrome P450 (CYP119) from Sulfolobus solfataricus: high resolution structure and functional properties. J.Inorg.Biochem., 91, 2002
|
|
1QKT
| MUTANT ESTROGEN NUCLEAR RECEPTOR LIGAND BINDING DOMAIN COMPLEXED WITH ESTRADIOL | Descriptor: | ESTRADIOL, ESTRADIOL RECEPTOR | Authors: | Ruff, M, Gangloff, M, Eiler, S, Duclaud, S, Wurtz, J.M, Moras, D. | Deposit date: | 1999-08-05 | Release date: | 2000-08-18 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal Structure of a Mutant Heralpha Ligand- Binding Domain Reveals Key Structural Features for the Mechanism of Partial Agonism J.Biol.Chem., 276, 2001
|
|
3WE7
| Crystal Structure of Diacetylchitobiose Deacetylase from Pyrococcus horikoshii | Descriptor: | ACETIC ACID, GLYCEROL, HEXANE-1,6-DIOL, ... | Authors: | Mine, S, Nakamura, T, Fukuda, Y, Inoue, T, Uegaki, K, Sato, T. | Deposit date: | 2013-07-01 | Release date: | 2014-05-07 | Last modified: | 2014-08-20 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Expression from engineered Escherichia coli chromosome and crystallographic study of archaeal N,N'-diacetylchitobiose deacetylase Febs J., 281, 2014
|
|
1WU5
| Crystal structure of reducing-end-xylose releasing exo-oligoxylanase complexed with xylose | Descriptor: | GLYCEROL, NICKEL (II) ION, beta-D-xylopyranose, ... | Authors: | Fushinobu, S, Hidaka, M, Honda, Y, Wakagi, T, Shoun, H, Kitaoka, M. | Deposit date: | 2004-12-01 | Release date: | 2005-02-22 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural Basis for the Specificity of the Reducing End Xylose-releasing Exo-oligoxylanase from Bacillus halodurans C-125 J.Biol.Chem., 280, 2005
|
|