3V6B
 
 | | VEGFR-2/VEGF-E complex structure | | Descriptor: | VEGF-E, Vascular endothelial growth factor receptor 2 | | Authors: | Brozzo, M.S, Leppanen, V.-M, Winkler, F.K, Kisko, K, Ballmer-Hofer, K. | | Deposit date: | 2011-12-19 | | Release date: | 2012-01-18 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (3.205 Å) | | Cite: | Thermodynamic and structural description of allosterically regulated VEGFR-2 dimerization.
Blood, 119, 2012
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3V2A
 | | VEGFR-2/VEGF-A COMPLEX STRUCTURE | | Descriptor: | Vascular endothelial growth factor A, Vascular endothelial growth factor receptor 2 | | Authors: | Brozzo, M.S, Leppanen, V.-M, Winkler, F.K, Ballmer-Hofer, K. | | Deposit date: | 2011-12-12 | | Release date: | 2012-01-18 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (3.204 Å) | | Cite: | Thermodynamic and structural description of allosterically regulated VEGFR-2 dimerization.
Blood, 119, 2012
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7TJ7
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7TIJ
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6YGN
 | | Titin kinase and its flanking domains | | Descriptor: | 1,2-ETHANEDIOL, GLYCEROL, Titin | | Authors: | Fleming, J.R, Franke, B, Bogomolovas, J, Mayans, O. | | Deposit date: | 2020-03-27 | | Release date: | 2021-04-07 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Titin kinase ubiquitination aligns autophagy receptors with mechanical signals in the sarcomere.
Embo Rep., 22, 2021
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6A69
 | | Cryo-EM structure of a P-type ATPase | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Neuroplastin, Plasma membrane calcium-transporting ATPase 1 | | Authors: | Gong, D.S, Chi, X.M, Ren, K, Huang, G.X.Y, Zhou, G.W, Yan, N, Lei, J.L, Zhou, Q. | | Deposit date: | 2018-06-27 | | Release date: | 2018-09-19 | | Last modified: | 2020-07-29 | | Method: | ELECTRON MICROSCOPY (4.11 Å) | | Cite: | Structure of the human plasma membrane Ca2+-ATPase 1 in complex with its obligatory subunit neuroplastin.
Nat Commun, 9, 2018
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8TKT
 | | ZIG-4-INS-6 complex, C-centered monoclinic form | | Descriptor: | Probable insulin-like peptide beta-type 5, Zwei Ig domain protein zig-4 | | Authors: | Cheng, S, Baltrusaitis, E, Aziz, Z, Nawrocka, W.I, Ozkan, E. | | Deposit date: | 2023-07-25 | | Release date: | 2024-08-28 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Nematode Extracellular Protein Interactome Expands Connections between Signaling Pathways
To Be Published
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8TKU
 | | ZIG-4-INS-6 complex, primitive monoclinic form | | Descriptor: | Probable insulin-like peptide beta-type 5, Zwei Ig domain protein zig-4 | | Authors: | Cheng, S, Baltrusaitis, E, Aziz, Z, Nawrocka, W.I, Ozkan, E. | | Deposit date: | 2023-07-25 | | Release date: | 2024-08-28 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Nematode Extracellular Protein Interactome Expands Connections between Signaling Pathways
To Be Published
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7LBF
 | | CryoEM structure of the HCMV Trimer gHgLgO in complex with human Platelet-derived growth factor receptor alpha and neutralizing fabs 13H11 and MSL-109 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein H, ... | | Authors: | Kschonsak, M, Rouge, L, Arthur, C.P, Hoangdung, H, Patel, N, Kim, I, Johnson, M, Kraft, E, Rohou, A.L, Gill, A, Martinez-Martin, N, Payandeh, J, Ciferri, C. | | Deposit date: | 2021-01-07 | | Release date: | 2021-03-10 | | Last modified: | 2021-03-17 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | Structures of HCMV Trimer reveal the basis for receptor recognition and cell entry.
Cell, 184, 2021
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8TK9
 | | ZIG-4-INS-6 complex, tetragonal form | | Descriptor: | GLYCEROL, Probable insulin-like peptide beta-type 5, SULFATE ION, ... | | Authors: | Cheng, S, Baltrusaitis, E, Aziz, Z, Nawrocka, W.I, Ozkan, E. | | Deposit date: | 2023-07-25 | | Release date: | 2024-08-28 | | Method: | X-RAY DIFFRACTION (1.3 Å) | | Cite: | Nematode Extracellular Protein Interactome Expands Connections between Signaling Pathways
To Be Published
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7LRG
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4EDQ
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7RAM
 | | Cryo-EM Structure of the HCMV gHgLgO Trimer Derived from AD169 and TR strains in complex with PDGFRalpha | | Descriptor: | Envelope glycoprotein H, Envelope glycoprotein L, Envelope glycoprotein O, ... | | Authors: | Liu, J, Vanarsdall, A.L, Chen, D, Johnson, D.C, Jardetzky, T.S. | | Deposit date: | 2021-07-02 | | Release date: | 2022-06-08 | | Method: | ELECTRON MICROSCOPY (3.43 Å) | | Cite: | Cryo-Electron Microscopy Structure and Interactions of the Human Cytomegalovirus gHgLgO Trimer with Platelet-Derived Growth Factor Receptor Alpha.
Mbio, 12, 2021
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5FM5
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1KOA
 | | TWITCHIN KINASE FRAGMENT (C.ELEGANS), AUTOREGULATED PROTEIN KINASE AND IMMUNOGLOBULIN DOMAINS | | Descriptor: | TWITCHIN | | Authors: | Kobe, B, Heierhorst, J, Feil, S.C, Parker, M.W, Benian, G.M, Weiss, K.R, Kemp, B.E. | | Deposit date: | 1996-06-28 | | Release date: | 1997-03-12 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Giant protein kinases: domain interactions and structural basis of autoregulation.
EMBO J., 15, 1996
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7TIT
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6IAA
 | | hRobo2 ectodomain | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Roundabout homolog 2, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | | Authors: | Barak, R, Isupov, N.M, Opatowsky, Y. | | Deposit date: | 2018-11-26 | | Release date: | 2019-03-13 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (3.6 Å) | | Cite: | Structural Principles in Robo Activation and Auto-inhibition.
Cell, 177, 2019
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3ZYI
 | | NetrinG2 in complex with NGL2 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, LEUCINE-RICH REPEAT-CONTAINING PROTEIN 4, ... | | Authors: | Seiradake, E, Coles, C.H, Perestenko, P.V, Harlos, K, McIlhinney, R.A.J, Aricescu, A.R, Jones, E.Y. | | Deposit date: | 2011-08-23 | | Release date: | 2011-10-05 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structural Basis for Cell Surface Patterning Through Netring-Ngl Interactions
Embo J., 30, 2011
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3ZYJ
 | | NetrinG1 in complex with NGL1 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, LEUCINE-RICH REPEAT-CONTAINING PROTEIN 4C, ... | | Authors: | Seiradake, E, Coles, C.H, Perestenko, P.V, Harlos, K, McIlhinney, R.A.J, Aricescu, A.R, Jones, E.Y. | | Deposit date: | 2011-08-23 | | Release date: | 2011-10-05 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (3.25 Å) | | Cite: | Structural Basis for Cell Surface Patterning Through Netring-Ngl Interactions.
Embo J., 30, 2011
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5FTT
 | | Octameric complex of Latrophilin 3 (Lec, Olf) , Unc5D (Ig, Ig2, TSP1) and FLRT2 (LRR) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ADHESION G PROTEIN-COUPLED RECEPTOR L3, CALCIUM ION, ... | | Authors: | Jackson, V.A, Mehmood, S, Chavent, M, Roversi, P, Carrasquero, M, del Toro, D, Seyit-Bremer, G, Ranaivoson, F.M, Comoletti, D, Sansom, M.S.P, Robinson, C.V, Klein, R, Seiradake, E. | | Deposit date: | 2016-01-15 | | Release date: | 2016-05-04 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (3.4 Å) | | Cite: | Super-Complexes of Adhesion Gpcrs and Neural Guidance Receptors
Nat.Commun., 7, 2016
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4PBX
 | | Crystal structure of the six N-terminal domains of human receptor protein tyrosine phosphatase sigma | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Receptor-type tyrosine-protein phosphatase S | | Authors: | Coles, C.H, Mitakidis, N, Zhang, P, Elegheert, J, Lu, W, Stoker, A.W, Nakagawa, T, Craig, A.M, Jones, E.Y, Aricescu, A.R. | | Deposit date: | 2014-04-14 | | Release date: | 2014-11-12 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (3.15 Å) | | Cite: | Structural basis for extracellular cis and trans RPTP sigma signal competition in synaptogenesis.
Nat Commun, 5, 2014
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4PBW
 | | Crystal structure of chicken receptor protein tyrosine phosphatase sigma in complex with TrkC | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, NT-3 growth factor receptor, Protein-tyrosine phosphatase CRYPalpha1 isoform | | Authors: | Coles, C.H, Mitakidis, N, Zhang, P, Elegheert, J, Lu, W, Stoker, A.W, Nakagawa, T, Craig, A.M, Jones, E.Y, Aricescu, A.R. | | Deposit date: | 2014-04-14 | | Release date: | 2014-11-12 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (3.05 Å) | | Cite: | Structural basis for extracellular cis and trans RPTP sigma signal competition in synaptogenesis.
Nat Commun, 5, 2014
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8K53
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8K3J
 | | Structure of human CNTN2 immunoglobulin domains 1-6 homo-dimer | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Contactin-2, ... | | Authors: | Zhang, Z.Z. | | Deposit date: | 2023-07-16 | | Release date: | 2024-07-17 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Structure of human CNTN2 immunoglobulin domains 1-6 homo-dimer
To Be Published
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5T89
 | | Crystal structure of VEGF-A in complex with VEGFR-1 domains D1-6 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Vascular endothelial growth factor A, ... | | Authors: | Markovic-Mueller, S, Stuttfeld, E, Asthana, M, Weinert, T, Bliven, S, Goldie, K.N, Kisko, K, Capitani, G, Ballmer-Hofer, K. | | Deposit date: | 2016-09-07 | | Release date: | 2017-02-01 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (4 Å) | | Cite: | Structure of the Full-length VEGFR-1 Extracellular Domain in Complex with VEGF-A.
Structure, 25, 2017
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