1F5N
| HUMAN GUANYLATE BINDING PROTEIN-1 IN COMPLEX WITH THE GTP ANALOGUE, GMPPNP. | Descriptor: | INTERFERON-INDUCED GUANYLATE-BINDING PROTEIN 1, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | Authors: | Prakash, B, Renault, L, Praefcke, G.J.K, Herrmann, C, Wittinghofer, A. | Deposit date: | 2000-06-15 | Release date: | 2000-09-27 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Triphosphate structure of guanylate-binding protein 1 and implications for nucleotide binding and GTPase mechanism. EMBO J., 19, 2000
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1DG3
| STRUCTURE OF HUMAN GUANYLATE BINDING PROTEIN-1 IN NUCLEOTIDE FREE FORM | Descriptor: | PROTEIN (INTERFERON-INDUCED GUANYLATE-BINDING PROTEIN 1) | Authors: | Prakash, B, Praefcke, G.J.K, Renault, L, Wittinghofer, A, Herrmann, C. | Deposit date: | 1999-11-23 | Release date: | 2000-10-11 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structure of human guanylate-binding protein 1 representing a unique class of GTP-binding proteins. Nature, 403, 2000
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2D4H
| Crystal-structure of the N-terminal large GTPase Domain of human Guanylate Binding protein 1 (hGBP1) in complex with GMP | Descriptor: | GUANOSINE-5'-MONOPHOSPHATE, Interferon-induced guanylate-binding protein 1 | Authors: | Ghosh, A, Praefcke, G.J.K, Renault, L, Wittinghofer, A, Herrmann, C. | Deposit date: | 2005-10-19 | Release date: | 2006-03-07 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | How guanylate-binding proteins achieve assembly-stimulated processive cleavage of GTP to GMP. Nature, 440, 2006
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2B8W
| Crystal-structure of the N-terminal Large GTPase Domain of human Guanylate Binding protein 1 (hGBP1) in complex with GMP/AlF4 | Descriptor: | GUANOSINE-5'-MONOPHOSPHATE, Interferon-induced guanylate-binding protein 1, MAGNESIUM ION, ... | Authors: | Ghosh, A, Praefcke, G.J.K, Renault, L, Wittinghofer, A, Herrmann, C. | Deposit date: | 2005-10-10 | Release date: | 2006-03-07 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.22 Å) | Cite: | How guanylate-binding proteins achieve assembly-stimulated processive cleavage of GTP to GMP. Nature, 440, 2006
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2B92
| Crystal-structure of the N-terminal Large GTPase Domain of human Guanylate Binding protein 1 (hGBP1) in complex with GDP/AlF3 | Descriptor: | ALUMINUM FLUORIDE, GUANOSINE-5'-DIPHOSPHATE, Interferon-induced guanylate-binding protein 1, ... | Authors: | Ghosh, A, Praefcke, G.J.K, Renault, L, Wittinghofer, A, Herrmann, C. | Deposit date: | 2005-10-10 | Release date: | 2006-03-07 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | How guanylate-binding proteins achieve assembly-stimulated processive cleavage of GTP to GMP. Nature, 440, 2006
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2BC9
| Crystal-structure of the N-terminal large GTPase Domain of human Guanylate Binding protein 1 (hGBP1) in complex with non-hydrolysable GTP analogue GppNHp | Descriptor: | Interferon-induced guanylate-binding protein 1, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | Authors: | Ghosh, A, Praefcke, G.J.K, Renault, L, Wittinghofer, A, Herrmann, C. | Deposit date: | 2005-10-19 | Release date: | 2006-03-07 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | How guanylate-binding proteins achieve assembly-stimulated processive cleavage of GTP to GMP. Nature, 440, 2006
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3Q5E
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3Q5D
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3QNU
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3QOF
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4IDP
| human atlastin-1 1-446, N440T, GppNHp | Descriptor: | Atlastin-1, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | Authors: | Byrnes, L.J, Singh, A, Szeto, K, Benvin, N.M, O'Donnell, J.P, Zipfel, W.R, Sondermann, H. | Deposit date: | 2012-12-12 | Release date: | 2013-01-09 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.587 Å) | Cite: | Structural basis for conformational switching and GTP loading of the large G protein atlastin. Embo J., 32, 2013
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4IDQ
| human atlastin-1 1-446, N440T, GDPAlF4- | Descriptor: | Atlastin-1, GUANOSINE-5'-DIPHOSPHATE, HEXAETHYLENE GLYCOL, ... | Authors: | Byrnes, L.J, Singh, A, Szeto, K, Benvin, N.M, O'Donnell, J.P, Zipfel, W.R, Sondermann, H. | Deposit date: | 2012-12-12 | Release date: | 2013-01-09 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.295 Å) | Cite: | Structural basis for conformational switching and GTP loading of the large G protein atlastin. Embo J., 32, 2013
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4IDN
| Human atlastin-1 1-446, C-his6, GppNHp | Descriptor: | Atlastin-1, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | Authors: | Byrnes, L.J, Singh, A, Szeto, K, Benvin, N.M, O'Donnell, J.P, Zipfel, W.R, Sondermann, H. | Deposit date: | 2012-12-12 | Release date: | 2013-01-09 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.252 Å) | Cite: | Structural basis for conformational switching and GTP loading of the large G protein atlastin. Embo J., 32, 2013
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4IDO
| human atlastin-1 1-446, C-his6, GDPAlF4- | Descriptor: | Atlastin-1, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Byrnes, L.J, Singh, A, Szeto, K, Benvin, N.M, O'Donnell, J.P, Zipfel, W.R, Sondermann, H. | Deposit date: | 2012-12-12 | Release date: | 2013-01-09 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.091 Å) | Cite: | Structural basis for conformational switching and GTP loading of the large G protein atlastin. Embo J., 32, 2013
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3X1D
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5VGR
| Human Atlastin-3, GDP-bound | Descriptor: | Atlastin-3, GUANOSINE-5'-DIPHOSPHATE | Authors: | O'Donnell, J.P, Sondermann, H. | Deposit date: | 2017-04-11 | Release date: | 2017-05-17 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.096 Å) | Cite: | Timing and Reset Mechanism of GTP Hydrolysis-Driven Conformational Changes of Atlastin. Structure, 25, 2017
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6B9F
| Human ATL1 mutant - F151S bound to GDPAlF4- | Descriptor: | Atlastin-1, GLYCEROL, GUANOSINE-5'-DIPHOSPHATE, ... | Authors: | O'Donnell, J.P, Sondermann, H. | Deposit date: | 2017-10-10 | Release date: | 2017-12-06 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | A hereditary spastic paraplegia-associated atlastin variant exhibits defective allosteric coupling in the catalytic core. J. Biol. Chem., 293, 2018
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6B9G
| human ATL1 GTPase domain bound to GDP | Descriptor: | Atlastin-1, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION | Authors: | O'Donnell, J.P, Sondermann, H. | Deposit date: | 2017-10-10 | Release date: | 2017-12-06 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | A hereditary spastic paraplegia-associated atlastin variant exhibits defective allosteric coupling in the catalytic core. J. Biol. Chem., 293, 2018
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6B9E
| Human ATL1 mutant - R77A / F151S bound to GDP | Descriptor: | Atlastin-1, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | O'Donnell, J.P, Sondermann, H. | Deposit date: | 2017-10-10 | Release date: | 2017-12-06 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | A hereditary spastic paraplegia-associated atlastin variant exhibits defective allosteric coupling in the catalytic core. J. Biol. Chem., 293, 2018
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6B9D
| Human ATL1 mutant - R77A bound to GDP | Descriptor: | Atlastin-1, GLYCEROL, GUANOSINE-5'-DIPHOSPHATE, ... | Authors: | O'Donnell, J.P, Sondermann, H. | Deposit date: | 2017-10-10 | Release date: | 2017-12-06 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | A hereditary spastic paraplegia-associated atlastin variant exhibits defective allosteric coupling in the catalytic core. J. Biol. Chem., 293, 2018
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6K2D
| The crystal structure of GBP1 with LRR domain of IpaH9.8 | Descriptor: | E3 ubiquitin-protein ligase ipaH9.8, Guanylate-binding protein 1 | Authors: | Ji, C.G, Xiao, J.Y. | Deposit date: | 2019-05-14 | Release date: | 2019-06-12 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (3.6 Å) | Cite: | Structural mechanism for guanylate-binding proteins (GBPs) targeting by the Shigella E3 ligase IpaH9.8. Plos Pathog., 15, 2019
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6K1Z
| Crystal structure of farnesylated hGBP1 | Descriptor: | FARNESYL, Guanylate-binding protein 1 | Authors: | Du, S, Xiao, J.Y. | Deposit date: | 2019-05-13 | Release date: | 2019-06-12 | Last modified: | 2019-12-25 | Method: | X-RAY DIFFRACTION (2.307 Å) | Cite: | Structural mechanism for guanylate-binding proteins (GBPs) targeting by the Shigella E3 ligase IpaH9.8. Plos Pathog., 15, 2019
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6LOJ
| The complex structure of IpaH9.8-LRR and hGBP1 | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, Guanylate-binding protein 1, Invasion plasmid antigen | Authors: | Ye, Y, Huang, H. | Deposit date: | 2020-01-06 | Release date: | 2020-12-23 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.72 Å) | Cite: | Substrate-binding destabilizes the hydrophobic cluster to relieve the autoinhibition of bacterial ubiquitin ligase IpaH9.8. Commun Biol, 3, 2020
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6VKJ
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7CKF
| The N-terminus of interferon-inducible antiviral protein-dimer | Descriptor: | ALUMINUM FLUORIDE, GUANOSINE-5'-DIPHOSPHATE, Guanylate-binding protein 5, ... | Authors: | Cui, W, Yang, H.T. | Deposit date: | 2020-07-16 | Release date: | 2021-05-05 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.284 Å) | Cite: | Structural basis for GTP-induced dimerization and antiviral function of guanylate-binding proteins. Proc.Natl.Acad.Sci.USA, 118, 2021
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