PDB: 47902 resultsInfo pagesStatus searchChemie searchBIRD

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4UQS	Structure of Bacillus subtilis Nitric Oxide Synthase in complex with 3-Bromo-7-Nitroindazole Descriptor: 3-BROMO-7-NITROINDAZOLE, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... Authors: Holden, J.K, Poulos, T.L. Deposit date: 2014-06-24 Release date: 2014-09-17 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.15 Å) Cite: Identification of Redox Partners and Development of a Novel Chimeric Bacterial Nitric Oxide Synthase for Structure Activity Analyses. J.Biol.Chem., 289, 2014
4UQV	methanococcus jannaschii serine hydroxymethyl-transferase in complex with PLP Descriptor: PYRIDOXAL-5'-PHOSPHATE, SERINE HYDROXYMETHYLTRANSFERASE Authors: Saccoccia, F, Angelucci, F, Ilari, A. Deposit date: 2014-06-25 Release date: 2014-07-30 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (3 Å) Cite: The Crystal Structure of Archaeal Serine Hydroxymethyltransferase Reveals Idiosyncratic Features Likely Required to Withstand High Temperatures. Proteins, 82, 2014
4UXD	2-keto 3-deoxygluconate aldolase from Picrophilus torridus Descriptor: 1,2-ETHANEDIOL, 2-DEHYDRO-3-DEOXY-D-GLUCONATE/2-DEHYDRO-3-DEOXY-PHOSPHOGLUCONATE ALDOLASE, DI(HYDROXYETHYL)ETHER, ... Authors: Priftis, A, Zaitsev, V, Reher, M, Johnsen, U, Danson, M.J, Taylor, G.L, Schoenheit, P, Crennell, S.J. Deposit date: 2014-08-22 Release date: 2015-09-30 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Insights into the Substrate Specificity of Archaeal Entner-Doudoroff Aldolases: The Structures of Picrophilus torridus 2-Keto-3-deoxygluconate Aldolase and Sulfolobus solfataricus 2-Keto-3-deoxy-6-phosphogluconate Aldolase in Complex with 2-Keto-3-deoxy-6-phosphogluconate. Biochemistry, 57, 2018
4V4K	Bacteriophage P22 Portal Protein bound to middle Tail Factor GP4. This file contain the second biological assembly Descriptor: PACKAGED DNA STABILIZATION PROTEIN GP4, PORTAL PROTEIN Authors: Olia, A.S, Cingolani, G. Deposit date: 2010-04-19 Release date: 2014-07-09 Last modified: 2021-10-06 Method: X-RAY DIFFRACTION (3.251 Å) Cite: Three-dimensional structure of a viral genome-delivery portal vertex. Nat.Struct.Mol.Biol., 18, 2011
9GGQ	E.coli gyrase holocomplex with cleaved chirally wrapped 217 bp DNA fragment and moxifloxacin Descriptor: 1-cyclopropyl-6-fluoro-8-methoxy-7-[(4aS,7aS)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid, DNA gyrase subunit A, DNA gyrase subunit B, ... Authors: Ghilarov, D, Heddle, J.G, Pabis, M. Deposit date: 2024-08-13 Release date: 2024-09-11 Method: ELECTRON MICROSCOPY (2.6 Å) Cite: Structural basis of chiral wrap and T-segment capture by Escherichia coli DNA gyrase Proceedings of the National Academy of Sciences USA, 2024
9GDK	Jumonji domain-containing protein 1C with crystallization epitope mutations L2440Y:G2444H Descriptor: Probable JmjC domain-containing histone demethylation protein 2C Authors: Fairhead, M, Strain-Damerell, C, Ye, M, Mackinnon, S.R, Pinkas, D, MacLean, E.M, Koekemoer, L, Damerell, D, Krojer, T, Arrowsmith, C.H, Edwards, A, Bountra, C, Yue, W, Burgess-Brown, N, Marsden, B, von Delft, F, Structural Genomics Consortium (SGC) Deposit date: 2024-08-05 Release date: 2024-08-21 Method: X-RAY DIFFRACTION (1.78 Å) Cite: A fast, parallel method for efficiently exploring crystallization behaviour of large numbers of protein variants To Be Published
9FZK	SARS CoV-2 nsp10 in complex with theExoN domain from nsp14 Descriptor: Guanine-N7 methyltransferase nsp14, Non-structural protein 11, ZINC ION Authors: Fisher, S.Z. Deposit date: 2024-07-05 Release date: 2024-07-17 Method: X-RAY DIFFRACTION (1.3 Å) Cite: SARS CoV-2 nsp10 in complex with theExoN domain from nsp14 To Be Published
9ICE	DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SEVEN BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF DATP (1 MILLIMOLAR) AND CUCL2 (0.1 MILLIMOLAR) Descriptor: DNA (5'-D(*CP*AP*TP*TP*AP*GP*AP*A)-3'), DNA (5'-D(*TP*CP*TP*AP*AP*TP*G)-3'), PROTEIN (DNA POLYMERASE BETA (E.C.2.7.7.7)), ... Authors: Pelletier, H, Sawaya, M.R. Deposit date: 1995-12-15 Release date: 1996-11-15 Last modified: 2023-08-02 Method: X-RAY DIFFRACTION (3.3 Å) Cite: Characterization of the metal ion binding helix-hairpin-helix motifs in human DNA polymerase beta by X-ray structural analysis. Biochemistry, 35, 1996
9CHQ	Cryo-EM structure of the human ether-a-go-go related K+ channel (hERG) in 3 mM K+ Descriptor: Potassium voltage-gated channel subfamily H member 2 Authors: Lau, C.H.Y, Hunter, M.J, Vandenberg, J.I. Deposit date: 2024-07-01 Release date: 2024-08-21 Last modified: 2024-09-11 Method: ELECTRON MICROSCOPY (3 Å) Cite: Potassium dependent structural changes in the selectivity filter of HERG potassium channels. Nat Commun, 15, 2024
9EPM	Mpro from SARS-CoV-2 with 4A mutation Descriptor: Non-structural protein 11 Authors: Plewka, J, Lis, K, Czarna, A, Pyrc, K, Kantyka, T, Chykunova, Y. Deposit date: 2024-03-19 Release date: 2024-04-17 Last modified: 2024-04-24 Method: X-RAY DIFFRACTION (1.981 Å) Cite: SARS-CoV-2 M pro oligomerization as a potential target for therapy. Int.J.Biol.Macromol., 267, 2024
8ZRI	EcGK filament at APO state. Descriptor: Glutamate 5-kinase Authors: Zhang, T, Leng, Q, Liu, L.J. Deposit date: 2024-06-04 Release date: 2024-08-07 Method: ELECTRON MICROSCOPY (2.67 Å) Cite: EcGPR tetramer with catalytic intermediates To Be Published
9ICA	DNA POLYMERASE BETA (E.C.2.7.7.7)/DNA COMPLEX + 2'-DEOXYADENOSINE-5'-O-(1-THIOTRIPHOSPHATE), SOAKED IN THE PRESENCE OF DATP(ALPHA)S AND MNCL2 Descriptor: 2'-DEOXYADENOSINE 5'-O-(1-THIOTRIPHOSPHATE), DNA (5'-D(*CP*AP*TP*TP*AP*GP*AP*A)-3'), DNA (5'-D(*TP*CP*TP*AP*AP*TP*G)-3'), ... Authors: Pelletier, H, Sawaya, M.R. Deposit date: 1995-12-15 Release date: 1995-12-15 Last modified: 2023-08-02 Method: X-RAY DIFFRACTION (3 Å) Cite: Characterization of the metal ion binding helix-hairpin-helix motifs in human DNA polymerase beta by X-ray structural analysis. Biochemistry, 35, 1996
9CEJ	Caulobacter crescentus FljJK flagellar filament (asymmetrical) Descriptor: Flagellin Authors: Sanchez, J.C, Montemayor, E.J, Ploscariu, N.T, Parrell, D, Baumgardt, J.K, Yang, J.E, Sibert, B, Cai, K, Wright, E.R. Deposit date: 2024-06-26 Release date: 2024-08-28 Method: ELECTRON MICROSCOPY (2.53 Å) Cite: Direct evidence for multi-flagellin filament stabilization via atomic-level architecture of Caulobacter crescentus flagellar filaments To Be Published
9GH3	pleckstrin homology domain interacting protein with crystallization epitope mutations L1408N:R1409E Descriptor: 1,2-ETHANEDIOL, PH-interacting protein Authors: Fairhead, M, Strain-Damerell, C, Ye, M, Mackinnon, S.R, Pinkas, D, MacLean, E.M, Koekemoer, L, Damerell, D, Krojer, T, Arrowsmith, C.H, Edwards, A, Yue, W, Burgess-Brown, N, Marsden, B, von Delft, F, Structural Genomics Consortium (SGC) Deposit date: 2024-08-14 Release date: 2024-08-21 Method: X-RAY DIFFRACTION (1.19 Å) Cite: A fast, parallel method for efficiently exploring crystallization behaviour of large numbers of protein variants To Be Published
9ICL	DNA POLYMERASE BETA (E.C.2.7.7.7)/DNA COMPLEX, SOAKED IN THE PRESENCE OF PYROPHOSPHATE AND MNCL2 Descriptor: DNA (5'-D(*CP*AP*GP*AP*TP*G)-3'), DNA (5'-D(*CP*AP*TP*CP*TP*GP*T)-3'), MANGANESE (II) ION, ... Authors: Pelletier, H, Sawaya, M.R. Deposit date: 1996-01-04 Release date: 1996-11-15 Last modified: 2023-08-02 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Characterization of the metal ion binding helix-hairpin-helix motifs in human DNA polymerase beta by X-ray structural analysis Biochemistry, 35, 1996
9F9A	Crystal structure of MUS81-EME1 bound by compound 12. Descriptor: 2-naphthalen-2-yl-5-oxidanyl-6-oxidanylidene-1H-pyrimidine-4-carboxylic acid, Crossover junction endonuclease EME1, Crossover junction endonuclease MUS81, ... Authors: Collie, G.W. Deposit date: 2024-05-07 Release date: 2024-06-19 Last modified: 2024-07-31 Method: X-RAY DIFFRACTION (2.911 Å) Cite: Fragment-Based Discovery of Novel MUS81 Inhibitors. Acs Med.Chem.Lett., 15, 2024
9ICC	DNA POLYMERASE BETA (E.C.2.7.7.7)/DNA COMPLEX + 2'-DEOXYADENOSINE-5'-TRIPHOSPHATE, SOAKED IN THE PRESENCE OF DATP AND CRCL3 Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CHROMIUM ION, DNA (5'-D(*CP*AP*TP*TP*AP*GP*AP*A)-3'), ... Authors: Pelletier, H, Sawaya, M.R. Deposit date: 1995-12-15 Release date: 1995-12-15 Last modified: 2023-08-02 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Characterization of the metal ion binding helix-hairpin-helix motifs in human DNA polymerase beta by X-ray structural analysis. Biochemistry, 35, 1996
9AXF	Structure of human calcium-sensing receptor in complex with chimeric Gq (miniGisq) protein in detergent Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3-(2-chlorophenyl)-N-[(1R)-1-(3-methoxyphenyl)ethyl]propan-1-amine, ... Authors: Zuo, H, Park, J, Frangaj, A, Ye, J, Lu, G, Manning, J.J, Asher, W.B, Lu, Z, Hu, G, Wang, L, Mendez, J, Eng, E, Zhang, Z, Lin, X, Grasucci, R, Hendrickson, W.A, Clarke, O.B, Javitch, J.A, Conigrave, A.D, Fan, Q.R. Deposit date: 2024-03-06 Release date: 2024-04-17 Last modified: 2024-05-22 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: Promiscuous G-protein activation by the calcium-sensing receptor. Nature, 629, 2024
9ICK	DNA POLYMERASE BETA (E.C.2.7.7.7)/DNA COMPLEX, SOAKED IN THE PRESENCE OF ARTIFICIAL MOTHER LIQUOR Descriptor: DNA (5'-D(*CP*AP*GP*AP*TP*G)-3'), DNA (5'-D(*CP*AP*TP*CP*TP*GP*T)-3'), PROTEIN (DNA POLYMERASE BETA (E.C.2.7.7.7)), ... Authors: Pelletier, H, Sawaya, M.R. Deposit date: 1995-12-16 Release date: 1996-11-15 Last modified: 2023-08-02 Method: X-RAY DIFFRACTION (2.7 Å) Cite: A structural basis for metal ion mutagenicity and nucleotide selectivity in human DNA polymerase beta Biochemistry, 35, 1996
9EYW	Human PRMT5 in complex with AZ compound 21 Descriptor: (3~{S})-2-[(5-azanyl-1~{H}-pyrrolo[3,2-b]pyridin-2-yl)methyl]-6-fluoranyl-1'-[(4-fluorophenyl)methyl]spiro[isoindole-3,3'-pyrrolidine]-1,2'-dione, 5'-DEOXY-5'-METHYLTHIOADENOSINE, Methylosome protein WDR77, ... Authors: Debreczeni, J. Deposit date: 2024-04-09 Release date: 2024-08-14 Last modified: 2024-09-04 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Discovery and In Vivo Efficacy of AZ-PRMT5i-1, a Novel PRMT5 Inhibitor with High MTA Cooperativity. J.Med.Chem., 67, 2024
9CL9	WT 12C IM fraction, B-b3 with RluB bound Descriptor: 23S rRNA, Large ribosomal subunit protein bL20, Large ribosomal subunit protein bL21, ... Authors: Lee, J, Sheng, K, Williamson, J.R. Deposit date: 2024-07-10 Release date: 2024-07-24 Method: ELECTRON MICROSCOPY (5.04 Å) Cite: 50S ribosome assembly intermediates at low temperature reveal bound RluB To Be Published
9F2R	Influenza A/H17N10 polymerase with bound promoter and 3' end of template in active site Descriptor: 3' end of the promoter vRNA, 5' end of the promoter vRNA, 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE, ... Authors: Cusack, S, Drncova, P. Deposit date: 2024-04-23 Release date: 2024-09-18 Method: X-RAY DIFFRACTION (1.959 Å) Cite: High-resolution structure of a replication-initiation like configuration of influenza polymerase active site visualises the essential role of a conserved dibasic motif in the PA subunit To Be Published
5WBU	Crystal structure of mTOR(deltaN)-mLST8-PRAS40(alpha-helix & beta-strand) complex Descriptor: Proline-rich AKT1 substrate 1, Serine/threonine-protein kinase mTOR, Target of rapamycin complex subunit LST8 Authors: Pavletich, N.P, Yang, H. Deposit date: 2017-06-29 Release date: 2017-12-20 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (3.42 Å) Cite: Mechanisms of mTORC1 activation by RHEB and inhibition by PRAS40. Nature, 552, 2017
9ICM	DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SIX BASE PAIRS OF DOUBLE STRANDED DNA (NO 5'-PHOSPHATE) Descriptor: DNA (5'-D(*CP*AP*GP*AP*TP*G)-3'), DNA (5'-D(*CP*AP*TP*CP*TP*GP*T)-3'), PROTEIN (DNA POLYMERASE BETA (E.C.2.7.7.7)), ... Authors: Pelletier, H, Sawaya, M.R. Deposit date: 1995-12-16 Release date: 1996-11-15 Last modified: 2023-08-02 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Crystal structures of human DNA polymerase beta complexed with DNA: implications for catalytic mechanism, processivity, and fidelity Biochemistry, 35, 1996
9ICP	DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SIX BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF PYROPHOSPHATE (1 MILLIMOLAR) AND MGCL2 (5 MILLIMOLAR) Descriptor: DNA (5'-D(*CP*AP*GP*AP*TP*G)-3'), DNA (5'-D(*CP*AP*TP*CP*TP*GP*T)-3'), PROTEIN (DNA POLYMERASE BETA (E.C.2.7.7.7)), ... Authors: Pelletier, H, Sawaya, M.R. Deposit date: 1995-12-16 Release date: 1996-11-15 Last modified: 2023-08-02 Method: X-RAY DIFFRACTION (3.1 Å) Cite: A structural basis for metal ion mutagenicity and nucleotide selectivity in human DNA polymerase beta Biochemistry, 35, 1996

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