PDB: 277 resultsInfo pagesStatus searchChemie searchBIRD

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4FL9	Crystal Structure of bovine hsc70(aa1-554)E213A/D214A at 1.9A Resolution Descriptor: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, Heat shock cognate 71 kDa protein, trimethylamine oxide Authors: Grimm, C. Deposit date: 2012-06-14 Release date: 2013-10-02 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.901 Å) Cite: Crystal Structure of bovine hsc70(aa1-554)E213A/D214A at 1.9A Resolution TO BE PUBLISHED
4FSV	Crystal structure of a heat shock 70kDa protein 2 (HSPA2) from Homo sapiens at 1.80 A resolution Descriptor: Heat shock-related 70 kDa protein 2 Authors: Joint Center for Structural Genomics (JCSG), Partnership for T-Cell Biology (TCELL) Deposit date: 2012-06-27 Release date: 2012-07-18 Last modified: 2023-02-01 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Crystal structure of a heat shock 70kDa protein 2 (HSPA2) from Homo sapiens at 1.80 A resolution To be published
4GNI	Structure of the Ssz1 ATPase bound to ATP and Magnesium Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Putative heat shock protein Authors: Bange, G, Sinning, I. Deposit date: 2012-08-17 Release date: 2012-12-05 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.796 Å) Cite: Structural characterization of a eukaryotic chaperone-the ribosome-associated complex. Nat.Struct.Mol.Biol., 20, 2013
7KRW	Stimulating state of near full-length Hsp70 DnaK fused with a substrate peptide Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Chaperone protein DnaK fused with substrate peptide Authors: Wang, W, Hendrickson, W.A. Deposit date: 2020-11-20 Release date: 2021-09-15 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (7.7 Å) Cite: Conformational equilibria in allosteric control of Hsp70 chaperones. Mol.Cell, 81, 2021
7KO2	Restraining state of near full-length Hsp70 DnaK Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Chaperone protein DnaK, MAGNESIUM ION, ... Authors: Wang, W, Hendrickson, W.A. Deposit date: 2020-11-06 Release date: 2021-09-15 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.64 Å) Cite: Conformational equilibria in allosteric control of Hsp70 chaperones. Mol.Cell, 81, 2021
7KRU	Stimulating state of a truncated Hsp70 DnaK fused with a substrate peptide Descriptor: 1,3-PROPANDIOL, ADENOSINE-5'-TRIPHOSPHATE, Chaperone protein DnaK fused with substrate peptide, ... Authors: Wang, W, Hendrickson, W.A. Deposit date: 2020-11-20 Release date: 2021-09-15 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.82 Å) Cite: Conformational equilibria in allosteric control of Hsp70 chaperones. Mol.Cell, 81, 2021
7KRV	Stimulating state of disulfide-bridged Hsp70 DnaK Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Chaperone protein DnaK fused with substrate peptide, MAGNESIUM ION, ... Authors: Wang, W, Hendrickson, W.A. Deposit date: 2020-11-20 Release date: 2021-09-15 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.92 Å) Cite: Conformational equilibria in allosteric control of Hsp70 chaperones. Mol.Cell, 81, 2021
7KRT	Restraining state of a truncated Hsp70 DnaK Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Chaperone protein DnaK, MAGNESIUM ION Authors: Wang, W, Hendrickson, W.A. Deposit date: 2020-11-20 Release date: 2021-09-15 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.79 Å) Cite: Conformational equilibria in allosteric control of Hsp70 chaperones. Mol.Cell, 81, 2021
4HY9	Crystal structure of the substrate binding domain of E.coli DnaK in complex with pyrrhocoricin_LYZZ (residues 1 to 11) Descriptor: Chaperone protein DnaK, Pyrrhocoricin, SULFATE ION Authors: Zahn, M, Straeter, N. Deposit date: 2012-11-13 Release date: 2013-04-17 Last modified: 2017-11-15 Method: X-RAY DIFFRACTION (1.55 Å) Cite: Structural Studies on the Forward and Reverse Binding Modes of Peptides to the Chaperone DnaK. J.Mol.Biol., 425, 2013
4JWE	Crystal structure of the substrate binding domain of E.coli DnaK in complex with sheep Bac7(1-21) Descriptor: Cathelicidin-3, Chaperone protein DnaK, SULFATE ION Authors: Zahn, M, Straeter, N. Deposit date: 2013-03-27 Release date: 2013-11-13 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Structural Identification of DnaK Binding Sites within Bovine and Sheep Bactenecin Bac7. Protein Pept.Lett., 21, 2014
4JWI	Crystal structure of the substrate binding domain of E.coli DnaK in complex with sheep Bac7(35-43) Descriptor: Cathelicidin-3, Chaperone protein DnaK, SULFATE ION Authors: Zahn, M, Straeter, N. Deposit date: 2013-03-27 Release date: 2013-11-13 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Structural Identification of DnaK Binding Sites within Bovine and Sheep Bactenecin Bac7. Protein Pept.Lett., 21, 2014
4H5W	HSC70 NBD with betaine Descriptor: ACETATE ION, Heat shock cognate 71 kDa protein, MAGNESIUM ION, ... Authors: Stec, B. Deposit date: 2012-09-19 Release date: 2014-03-19 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.94 Å) Cite: New crystal structures of HSC-70 ATP binding domain confirm the role of individual binding pockets and suggest a new method of inhibition. Biochimie, 108, 2015
4JN4	Allosteric opening of the polypeptide-binding site when an Hsp70 binds ATP Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Chaperone protein DnaK, GLYCEROL, ... Authors: Qi, R, Sarbeng, E.B, Liu, Q, Le, K.Q, Xu, X, Xu, H, Yang, J, Wong, J.L, Vorvis, C, Hendrickson, W.A, Zhou, L, Liu, Q. Deposit date: 2013-03-14 Release date: 2013-05-29 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Allosteric opening of the polypeptide-binding site when an Hsp70 binds ATP. Nat.Struct.Mol.Biol., 20, 2013
4J8F	Crystal structure of a fusion protein containing the NBD of Hsp70 and the middle domain of Hip Descriptor: ADENOSINE-5'-DIPHOSPHATE, Heat shock 70 kDa protein 1A/1B, Hsc70-interacting protein, ... Authors: Li, Z, Bracher, A. Deposit date: 2013-02-14 Release date: 2013-07-03 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Structure and function of Hip, an attenuator of the Hsp70 chaperone cycle. Nat.Struct.Mol.Biol., 20, 2013
4H5T	HSC70 NBD with ADP and Mg Descriptor: ADENOSINE-5'-DIPHOSPHATE, Heat shock cognate 71 kDa protein, MAGNESIUM ION, ... Authors: Stec, B. Deposit date: 2012-09-18 Release date: 2014-03-19 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.9 Å) Cite: New crystal structures of HSC-70 ATP binding domain confirm the role of individual binding pockets and suggest a new method of inhibition. Biochimie, 108, 2015
4H5N	HSC70 NBD with PO4, Na, Cl Descriptor: CHLORIDE ION, GLYCEROL, Heat shock cognate 71 kDa protein, ... Authors: Stec, B. Deposit date: 2012-09-18 Release date: 2014-03-19 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.86 Å) Cite: New crystal structures of HSC-70 ATP binding domain confirm the role of individual binding pockets and suggest a new method of inhibition. Biochimie, 108, 2015
4JWC	Crystal structure of the substrate binding domain of E.coli DnaK in complex with bovine Bac7(1-16) Descriptor: Cathelicidin-3, Chaperone protein DnaK, SULFATE ION Authors: Zahn, M, Straeter, N. Deposit date: 2013-03-27 Release date: 2013-11-13 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Structural Identification of DnaK Binding Sites within Bovine and Sheep Bactenecin Bac7. Protein Pept.Lett., 21, 2014
4H5V	HSC70 NBD with Mg Descriptor: ACETATE ION, CHLORIDE ION, GLYCEROL, ... Authors: Stec, B. Deposit date: 2012-09-18 Release date: 2014-03-19 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.75 Å) Cite: New crystal structures of HSC-70 ATP binding domain confirm the role of individual binding pockets and suggest a new method of inhibition. Biochimie, 108, 2015
7N6M	Crystal structure of the substrate-binding domain of E. coli DnaK in complex with the peptide RQKPLLGLSR Descriptor: Alkaline phosphatase peptide, Chaperone protein DnaK, SULFATE ION Authors: Jansen, R.M, Ozden, C, Gierasch, L.M, Garman, S.C. Deposit date: 2021-06-08 Release date: 2021-06-23 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.82 Å) Cite: Selective promiscuity in the binding of E. coli Hsp70 to an unfolded protein. Proc.Natl.Acad.Sci.USA, 118, 2021
7N6K	Crystal structure of the substrate-binding domain of E. coli DnaK in complex with the peptide RALALLPLSR Descriptor: Alkaline phosphatase peptide, Chaperone protein DnaK, SULFATE ION Authors: Jansen, R.M, Ozden, C, Gierasch, L.M, Garman, S.C. Deposit date: 2021-06-08 Release date: 2021-06-23 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.55 Å) Cite: Selective promiscuity in the binding of E. coli Hsp70 to an unfolded protein. Proc.Natl.Acad.Sci.USA, 118, 2021
7N6J	Crystal structure of the substrate-binding domain of E. coli DnaK in complex with the peptide RKQSTIALALLPLLFTPRR Descriptor: Alkaline phosphatase peptide, Chaperone protein DnaK, SULFATE ION Authors: Jansen, R.M, Ozden, C, Gierasch, L.M, Garman, S.C. Deposit date: 2021-06-08 Release date: 2021-06-23 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2 Å) Cite: Selective promiscuity in the binding of E. coli Hsp70 to an unfolded protein. Proc.Natl.Acad.Sci.USA, 118, 2021
7N6L	Crystal structure of the substrate-binding domain of E. coli DnaK in complex with the peptide EANQQKPLLGLFADG Descriptor: Alkaline phosphatase peptide, Chaperone protein DnaK, GLYCEROL, ... Authors: Jansen, R.M, Ozden, C, Gierasch, L.M, Garman, S.C. Deposit date: 2021-06-08 Release date: 2021-06-23 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Selective promiscuity in the binding of E. coli Hsp70 to an unfolded protein. Proc.Natl.Acad.Sci.USA, 118, 2021
4H5R	HSC70 NBD with Na, Cl and glycerol Descriptor: CHLORIDE ION, GLYCEROL, Heat shock cognate 71 kDa protein, ... Authors: Stec, B. Deposit date: 2012-09-18 Release date: 2014-03-19 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.64 Å) Cite: New crystal structures of HSC-70 ATP binding domain confirm the role of individual binding pockets and suggest a new method of inhibition. Biochimie, 108, 2015
7KZI	Intermediate state (QQQ) of near full-length DnaK alternatively fused with a substrate peptide Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, Chaperone protein DnaK fused with substrate peptide,Chaperone protein DnaK fused with substrate peptide, ... Authors: Wang, W, Hendrickson, W.A. Deposit date: 2020-12-10 Release date: 2021-05-12 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.82 Å) Cite: Intermediates in allosteric equilibria of DnaK-ATP interactions with substrate peptides Acta Crystallogr.,Sect.D, 77, 2021
7KZU	Quasi-intermediate state (Q) of a truncated Hsp70 DnaK fused with a substrate peptide Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Chaperone protein DnaK fused with substrate peptide,Chaperone protein DnaK fused with substrate peptide, GLYCEROL, ... Authors: Wang, W, Hendrickson, W.A. Deposit date: 2020-12-10 Release date: 2021-05-12 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.15 Å) Cite: Intermediates in allosteric equilibria of DnaK-ATP interactions with substrate peptides Acta Crystallogr.,Sect.D, 77, 2021

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