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3IHB	Crystal Structure Analysis of Mglu in its tris and glutamate form Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLUTAMIC ACID, Salt-tolerant glutaminase Authors: Yoshimune, K, Shirakihara, Y. Deposit date: 2009-07-29 Release date: 2010-01-19 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Crystal structure of salt-tolerant glutaminase from Micrococcus luteus K-3 in the presence and absence of its product l-glutamate and its activator Tris Febs J., 277, 2010
3IDO	Crystal structure of protein tyrosine phosphatase from Entamoeba histolytica with a phosphotyrosine crude mimic HEPES molecule in the active site Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Protein tyrosine phosphatase Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2009-07-21 Release date: 2009-07-28 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Crystal structure and putative substrate identification for the Entamoeba histolytica low molecular weight tyrosine phosphatase. Mol.Biochem.Parasitol., 193, 2014
3IDZ	Crystal Structure of S378Q mutant TTHA0252 from Thermus thermophilus HB8 Descriptor: CITRATE ANION, Ribonuclease TTHA0252, SULFATE ION, ... Authors: Ishikawa, H, Nakagawa, N, Kuramitsu, S, Yokoyama, S, Masui, R, RIKEN Structural Genomics/Proteomics Initiative (RSGI) Deposit date: 2009-07-22 Release date: 2009-08-04 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Crystal Structure of S378Q mutant TTHA0252 from Thermus thermophilus HB8 To be Published
3IJ4	Cesium sites in the crystal structure of a functional acid sensing ion channel in the desensitized state Descriptor: Amiloride-sensitive cation channel 2, neuronal, CESIUM ION, ... Authors: Gonzales, E.B, Gouaux, E. Deposit date: 2009-08-03 Release date: 2009-11-10 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (3 Å) Cite: Pore architecture and ion sites in acid-sensing ion channels and P2X receptors. Nature, 460, 2009
3IER	Firefly luciferase apo structure (P41 form) with PEG 400 bound Descriptor: Luciferin 4-monooxygenase, TETRAETHYLENE GLYCOL Authors: Lovell, S, Battaile, K.P, Auld, D.S, Thorne, N, Lea, W.A, Maloney, D.J, Shen, M, Raj, G, Thomas, C.J, Simeonov, A, Hanzlik, R.P, Inglese, J. Deposit date: 2009-07-23 Release date: 2010-02-16 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Molecular basis for the high-affinity binding and stabilization of firefly luciferase by PTC124. Proc.Natl.Acad.Sci.USA, 107, 2010
3IF5	Crystal Structure Analysis of Mglu Descriptor: Salt-tolerant glutaminase Authors: Yoshimune, K, Shirakihara, Y. Deposit date: 2009-07-24 Release date: 2009-08-04 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (2.44 Å) Cite: Crystal structure of salt-tolerant glutaminase from Micrococcus luteus K-3 in the presence and absence of its product L-glutamate and its activator Tris. Febs J., 277, 2010
3IJG	Macrophage Migration Inhibitory Factor (MIF) Bound to the (R)-Stereoisomer of AV1013 Descriptor: (2R)-2-amino-1-[2-(1-methylethyl)pyrazolo[1,5-a]pyridin-3-yl]propan-1-one, CHLORIDE ION, Macrophage migration inhibitory factor Authors: Crichlow, G.V, Cho, Y, Lolis, E.J. Deposit date: 2009-08-04 Release date: 2010-06-16 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Allosteric inhibition of macrophage migration inhibitory factor revealed by ibudilast. Proc.Natl.Acad.Sci.USA, 107, 2010
3IFJ	Crystal structure of Mtu recA intein, splicing domain Descriptor: Endonuclease PI-MtuI, ZINC ION Authors: Van Roey, P, Belfort, M. Deposit date: 2009-07-24 Release date: 2009-10-06 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Selection and structure of hyperactive inteins: peripheral changes relayed to the catalytic center. J.Mol.Biol., 393, 2009
3IKE	Crystal structure of 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase from Burkholderia pseudomallei with cytosine Descriptor: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, 6-AMINOPYRIMIDIN-2(1H)-ONE, CHLORIDE ION, ... Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2009-08-05 Release date: 2009-08-18 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Leveraging structure determination with fragment screening for infectious disease drug targets: MECP synthase from Burkholderia pseudomallei. J Struct Funct Genomics, 12, 2011
3IG7	Novel CDK-5 inhibitors - crystal structure of inhibitor EFP with CDK-2 Descriptor: Cell division protein kinase 2, N-{1-[cis-3-(acetylamino)cyclobutyl]-1H-imidazol-4-yl}-2-(4-methoxyphenyl)acetamide Authors: Pandit, J. Deposit date: 2009-07-27 Release date: 2009-09-08 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Potent and cellularly active 4-aminoimidazole inhibitors of cyclin-dependent kinase 5/p25 for the treatment of Alzheimer's disease. Bioorg.Med.Chem.Lett., 19, 2009
3IMM	Crystal structure of Putative glycosyl hydrolase (YP_001301887.1) from Parabacteroides distasonis ATCC 8503 at 2.00 A resolution Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, Putative secreted glycosylhydrolase, ... Authors: Joint Center for Structural Genomics (JCSG) Deposit date: 2009-08-10 Release date: 2009-08-18 Last modified: 2023-02-01 Method: X-RAY DIFFRACTION (2 Å) Cite: Crystal structure of Putative glycosyl hydrolase (YP_001301887.1) from Parabacteroides distasonis ATCC 8503 at 2.00 A resolution To be published
3IH7	Crystal structure of catalytically active human 8-oxoguanine glycosylase distally crosslinked to guanine-containing DNA Descriptor: 5'-D(*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*G)-3', 5'-D(AP*TP*CP*TP*GP*GP*AP*CP*CP*TP*GP*CP*A)-3', N-glycosylase/DNA lyase Authors: Verdine, G.L, Crenshaw, C.M, Oo, K.S, Kutchukian, P.S. Deposit date: 2009-07-29 Release date: 2010-11-03 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (3.1 Å) Cite: A Catalytic Checkpoint in Base Excision by the Human 8-Oxoguanine DNA Glycosylase hOGG1 To be Published
3INO	1.95A Resolution Structure of Protective Antigen Domain 4 Descriptor: Protective antigen PA-63 Authors: Lovell, S, Williams, A.S, Anbanandam, A, El-Chami, R, Bann, J.G. Deposit date: 2009-08-12 Release date: 2009-11-03 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Domain 4 of the anthrax protective antigen maintains structure and binding to the host receptor CMG2 at low pH Protein Sci., 18, 2009
3II4	Structure of mycobacterial lipoamide dehydrogenase bound to a triazaspirodimethoxybenzoyl inhibitor Descriptor: Dihydrolipoyl dehydrogenase, FLAVIN-ADENINE DINUCLEOTIDE, N-[2-(2,4-dichlorophenyl)ethyl]-2-{8-[(2,4-dimethoxyphenyl)carbonyl]-4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]dec-3-yl}acetamide Authors: Lima, C.D. Deposit date: 2009-07-31 Release date: 2010-01-26 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.42 Å) Cite: Triazaspirodimethoxybenzoyls as selective inhibitors of mycobacterial lipoamide dehydrogenase . Biochemistry, 49, 2010
3IJV	Chicken egg white lysozyme by classical hanging drop vapour diffusion method Descriptor: Lysozyme C Authors: Pechkova, E, Tripathi, S.K, Nicolini, C. Deposit date: 2009-08-05 Release date: 2010-08-11 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Comparison of lysozyme crystals grown by APA and classical hanging drop method To be Published
3IJX	Crystal structure of the AMPA subunit GluR2 bound to the allosteric modulator, hydrochlorothiazide Descriptor: 6-chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide, GLUTAMIC ACID, Glutamate receptor 2, ... Authors: Ptak, C.P, Ahmed, A.H, Oswald, R.E. Deposit date: 2009-08-05 Release date: 2009-09-15 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.881 Å) Cite: Probing the allosteric modulator binding site of GluR2 with thiazide derivatives Biochemistry, 48, 2009
3IKF	Crystal structure of 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase from Burkholderia pseudomallei with FOL fragment 717, imidazo[2,,1-b][1,3]thiazol-6-ylmethanol Descriptor: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, ACETATE ION, CHLORIDE ION, ... Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2009-08-05 Release date: 2009-08-18 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.07 Å) Cite: Leveraging structure determination with fragment screening for infectious disease drug targets: MECP synthase from Burkholderia pseudomallei. J Struct Funct Genomics, 12, 2011
3IPH	Crystal structure of p38 in complex with a biphenylamide inhibitor Descriptor: 6-[5-(cyclopropylcarbamoyl)-2-methylphenyl]-N-(cyclopropylmethyl)pyridine-3-carboxamide, GLYCEROL, Mitogen-activated protein kinase 14, ... Authors: Somers, D.O. Deposit date: 2009-08-17 Release date: 2009-11-24 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.1 Å) Cite: p38alpha mitogen-activated protein kinase inhibitors: optimization of a series of biphenylamides to give a molecule suitable for clinical progression. J.Med.Chem., 52, 2009
3IMU	Transthyretin in complex with (E)-4-(3-aminostyryl)-2,6-dibromoaniline Descriptor: 4-[(E)-2-(3-aminophenyl)ethenyl]-2,6-dibromoaniline, Transthyretin Authors: Connelly, S, Wilson, I.A. Deposit date: 2009-08-11 Release date: 2010-01-12 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.4 Å) Cite: A substructure combination strategy to create potent and selective transthyretin kinetic stabilizers that prevent amyloidogenesis and cytotoxicity. J.Am.Chem.Soc., 132, 2010
3IN9	Crystal structure of heparin lyase I complexed with disaccharide heparin Descriptor: 4-deoxy-2-O-sulfo-alpha-L-threo-hex-4-enopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, CALCIUM ION, Heparin lyase I Authors: Han, Y.H, Ryu, K.S, Kim, H.Y, Jeon, Y.H. Deposit date: 2009-08-12 Release date: 2009-09-29 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2 Å) Cite: Structural snapshots of heparin depolymerization by heparin lyase I J.Biol.Chem., 284, 2009
3IQQ	X-ray structure of bovine TRTK12-Ca(2+)-S100B Descriptor: CALCIUM ION, Protein S100-B, TRTK12 peptide, ... Authors: Charpentier, T.H, Weber, D.J, Toth, E.A. Deposit date: 2009-08-20 Release date: 2010-02-02 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.01 Å) Cite: The Effects of CapZ Peptide (TRTK-12) Binding to S100B-Ca(2+) as Examined by NMR and X-ray Crystallography J.Mol.Biol., 396, 2010
3IQX	ADP complex of C.therm. Get3 in closed form Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Tail-anchored protein targeting factor Get3, ... Authors: Bozkurt, G, Wild, K, Sinning, I. Deposit date: 2009-08-21 Release date: 2009-12-15 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (3.5 Å) Cite: Structural insights into tail-anchored protein binding and membrane insertion by Get3. Proc.Natl.Acad.Sci.USA, 106, 2009
3IRC	Crystal structure analysis of dengue-1 envelope protein domain III Descriptor: ENVELOPE PROTEIN, SULFATE ION Authors: Nelson, C.A, Kim, T, Warren, J.T, Chruszcz, M, Minor, W, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID) Deposit date: 2009-08-21 Release date: 2009-09-29 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.25 Å) Cite: Crystal Structure Analysis of the Dengue-1 Envelope Protein Domain III To be Published
3ISE	Structure of mineralized Bfrb (double soak) from Pseudomonas aeruginosa to 2.8A Resolution Descriptor: Bacterioferritin, FE (III) ION, POTASSIUM ION, ... Authors: Lovell, S, Weeratunga, S.K, Battaile, K.P, Rivera, M. Deposit date: 2009-08-25 Release date: 2010-02-02 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Structural Studies of Bacterioferritin B from Pseudomonas aeruginosa Suggest a Gating Mechanism for Iron Uptake via the Ferroxidase Center Biochemistry, 49, 2010
3IT0	Crystal Structure Francisella tularensis histidine acid phosphatase complexed with phosphate Descriptor: 2-(2-METHOXYETHOXY)ETHANOL, Acid phosphatase, PENTAETHYLENE GLYCOL, ... Authors: Singh, H, Felts, R.L, Reilly, T.J, Tanner, J.J. Deposit date: 2009-08-27 Release date: 2009-11-10 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.692 Å) Cite: Crystal Structures of the histidine acid phosphatase from Francisella tularensis provide insight into substrate recognition. J.Mol.Biol., 394, 2009

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