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6I2S
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BU of 6i2s by Molmil
Crystal structure of the SucA domain of Mycobacterium smegmatis KGD (R802A) in complex with GarA, following 2-oxoglutarate soak
Descriptor: (4S)-4-{3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-(2-{[(S)-hydroxy(phosphonooxy)phosphoryl]oxy}ethyl)-4-methyl-1,3lambda~5~-thiazol-2-yl}-4-hydroxybutanoic acid, CALCIUM ION, Glycogen accumulation regulator GarA, ...
Authors:Wagner, T, Bellinzoni, M, Alzari, P.M.
Deposit date:2018-11-01
Release date:2019-05-22
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural insights into the functional versatility of an FHA domain protein in mycobacterial signaling.
Sci.Signal., 12, 2019
6THC
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BU of 6thc by Molmil
Crystal structure of Mycobacterium smegmatis CoaB in complex with CTP and (4-hydroxyphenyl)(2,3,4-trihydroxyphenyl)methanone
Descriptor: (4-hydroxyphenyl)-[2,3,4-tris(oxidanyl)phenyl]methanone, ACETATE ION, CALCIUM ION, ...
Authors:Mendes, V, Blaszczyk, M, Bryant, O, Cory-Wright, J, Blundell, T.L.
Deposit date:2019-11-19
Release date:2020-11-25
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.033 Å)
Cite:Inhibiting Mycobacterium tuberculosis CoaBC by targeting an allosteric site.
Nat Commun, 12, 2021
6I2R
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BU of 6i2r by Molmil
Crystal structure of the SucA domain of Mycobacterium smegmatis KGD (alpha-ketoglutarate decarboxylase), mutant R802A, in complex with GarA
Descriptor: CALCIUM ION, Glycogen accumulation regulator GarA, MAGNESIUM ION, ...
Authors:Wagner, T, Bellinzoni, M, Alzari, P.M.
Deposit date:2018-11-01
Release date:2019-05-22
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural insights into the functional versatility of an FHA domain protein in mycobacterial signaling.
Sci.Signal., 12, 2019
7JSR
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BU of 7jsr by Molmil
Crystal structure of the large glutamate dehydrogenase composed of 180 kDa subunits from Mycobacterium smegmatis
Descriptor: NAD-specific glutamate dehydrogenase
Authors:Lazaro, M, Melero, R, Huet, C, Lopez-Alonso, J.P, Delgado, S, Dodu, A, Bruch, E.M, Abriata, L.A, Alzari, P.M, Valle, M, Lisa, M.N.
Deposit date:2020-08-15
Release date:2021-06-09
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (6.27 Å)
Cite:3D architecture and structural flexibility revealed in the subfamily of large glutamate dehydrogenases by a mycobacterial enzyme.
Commun Biol, 4, 2021
4U5Q
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BU of 4u5q by Molmil
High resolution crystal structure of reductase (R) domain of nonribosomal peptide synthetase from Mycobacterium tuberculosis
Descriptor: 3,6,9,12,15,18,21,24,27-NONAOXANONACOSANE-1,29-DIOL, Peptide synthetase
Authors:Patel, K.D, Haque, A.S, Priyadarshan, K, Sankaranarayanan, R.
Deposit date:2014-07-25
Release date:2016-01-13
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.811 Å)
Cite:High resolution structure of R-domain of nonribosomal peptide synthetase from Mycobacterium tuberculosis
To Be Published
5OHZ
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BU of 5ohz by Molmil
Crystal structure of Mycolicibacterium hassiacum glucosylglycerate hydrolase (MhGgH) - SeMet derivative
Descriptor: GLYCEROL, Hydrolase, SERINE
Authors:Cereija, T.B, Macedo-Ribeiro, S, Pereira, P.J.B.
Deposit date:2017-07-18
Release date:2018-08-08
Last modified:2019-08-28
Method:X-RAY DIFFRACTION (2.036 Å)
Cite:The structural characterization of a glucosylglycerate hydrolase provides insights into the molecular mechanism of mycobacterial recovery from nitrogen starvation.
Iucrj, 6, 2019
8IDB
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BU of 8idb by Molmil
Cryo-EM structure of Mycobacterium tuberculosis FtsEX complex in peptidisc
Descriptor: Cell division ATP-binding protein FtsE, Cell division protein FtsX
Authors:Li, J, Xu, X, Luo, M.
Deposit date:2023-02-12
Release date:2023-10-04
Last modified:2023-12-20
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Regulation of the cell division hydrolase RipC by the FtsEX system in Mycobacterium tuberculosis.
Nat Commun, 14, 2023
5OI1
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BU of 5oi1 by Molmil
Crystal structure of Mycolicibacterium hassiacum glucosylglycerate hydrolase (MhGgH) D182A variant in complex with serine and glycerol
Descriptor: GLYCEROL, Hydrolase, SERINE
Authors:Cereija, T.B, Macedo-Ribeiro, S, Pereira, P.J.B.
Deposit date:2017-07-18
Release date:2018-08-08
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:The structural characterization of a glucosylglycerate hydrolase provides insights into the molecular mechanism of mycobacterial recovery from nitrogen starvation.
Iucrj, 6, 2019
2BM4
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BU of 2bm4 by Molmil
The Structure of MfpA (Rv3361c, C2 Crystal form). The Pentapeptide Repeat Protein from Mycobacterium tuberculosis Folds as A Right- handed Quadrilateral Beta-helix.
Descriptor: PENTAPEPTIDE REPEAT FAMILY PROTEIN
Authors:Hegde, S.S, Vetting, M.W, Roderick, S.L, Mitchenall, L.A, Maxwell, A, Takiff, H.E, Blanchard, J.S.
Deposit date:2005-03-09
Release date:2005-06-07
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:A Fluroquinolone Resistance Protein from Mycobacterium Tuberculosis that Mimics DNA
Science, 308, 2005
5OHC
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BU of 5ohc by Molmil
Crystal structure of Mycolicibacterium hassiacum glucosylglycerate hydrolase (MhGgH) in complex with glycerol
Descriptor: GLYCEROL, Hydrolase
Authors:Cereija, T.B, Macedo-Ribeiro, S, Pereira, P.J.B.
Deposit date:2017-07-14
Release date:2018-08-01
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2 Å)
Cite:The structural characterization of a glucosylglycerate hydrolase provides insights into the molecular mechanism of mycobacterial recovery from nitrogen starvation.
Iucrj, 6, 2019
5OIW
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BU of 5oiw by Molmil
Crystal structure of Mycolicibacterium hassiacum glucosylglycerate hydrolase (MhGgH) D182A variant in complex with glucosylglycerate
Descriptor: (2R)-2-(alpha-D-glucopyranosyloxy)-3-hydroxypropanoic acid, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
Authors:Cereija, T.B, Macedo-Ribeiro, S, Pereira, P.J.B.
Deposit date:2017-07-19
Release date:2018-08-08
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.71 Å)
Cite:The structural characterization of a glucosylglycerate hydrolase provides insights into the molecular mechanism of mycobacterial recovery from nitrogen starvation.
Iucrj, 6, 2019
5OJV
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BU of 5ojv by Molmil
Crystal structure of Mycolicibacterium hassiacum glucosylglycerate hydrolase (MhGgH) E419A variant in complex with mannosylglycerate
Descriptor: (2R)-3-hydroxy-2-(alpha-D-mannopyranosyloxy)propanoic acid, GLYCEROL, SERINE, ...
Authors:Cereija, T.B, Macedo-Ribeiro, S, Pereira, P.J.B.
Deposit date:2017-07-24
Release date:2018-08-08
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.062 Å)
Cite:The structural characterization of a glucosylglycerate hydrolase provides insights into the molecular mechanism of mycobacterial recovery from nitrogen starvation.
Iucrj, 6, 2019
5OI0
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BU of 5oi0 by Molmil
Crystal structure of Mycolicibacterium hassiacum glucosylglycerate hydrolase (MhGgH) in complex with serine and glycerol
Descriptor: GLYCEROL, SERINE, Uncharacterized protein
Authors:Cereija, T.B, Macedo-Ribeiro, S, Pereira, P.J.B.
Deposit date:2017-07-18
Release date:2018-08-08
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:The structural characterization of a glucosylglycerate hydrolase provides insights into the molecular mechanism of mycobacterial recovery from nitrogen starvation.
Iucrj, 6, 2019
4PWS
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BU of 4pws by Molmil
Crystal structure of secreted proline rich antigen MTC28 (Rv0040c) at 2.15 A with bound chloride from Mycobacterium tuberculosis
Descriptor: CHLORIDE ION, Proline-rich 28 kDa antigen
Authors:Kundu, P, Biswas, R, Mukherjee, S, Reinhard, L, Mueller-dieckmann, J, Weiss, M.S, Das, A.K.
Deposit date:2014-03-21
Release date:2015-03-25
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structure-based Epitope Mapping of Mycobacterium tuberculosis Secretary Antigen MTC28
J.Biol.Chem., 291, 2016
5OJ4
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BU of 5oj4 by Molmil
Crystal structure of Mycolicibacterium hassiacum glucosylglycerate hydrolase (MhGgH) D182A variant in complex with mannosylglycerate
Descriptor: (2R)-3-hydroxy-2-(alpha-D-mannopyranosyloxy)propanoic acid, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
Authors:Cereija, T.B, Macedo-Ribeiro, S, Pereira, P.J.B.
Deposit date:2017-07-20
Release date:2018-08-08
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:The structural characterization of a glucosylglycerate hydrolase provides insights into the molecular mechanism of mycobacterial recovery from nitrogen starvation.
Iucrj, 6, 2019
3DC2
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BU of 3dc2 by Molmil
Crystal structure of serine bound D-3-phosphoglycerate dehydrogenase from Mycobacterium tuberculosis
Descriptor: D-3-phosphoglycerate dehydrogenase, L(+)-TARTARIC ACID, SERINE
Authors:Dey, S, Sacchettini, J.C.
Deposit date:2008-06-03
Release date:2008-07-22
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural analysis of substrate and effector binding in Mycobacterium tuberculosis D-3-phosphoglycerate dehydrogenase
Biochemistry, 47, 2008
5OJU
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BU of 5oju by Molmil
Crystal structure of Mycolicibacterium hassiacum glucosylglycerate hydrolase (MhGgH) E419A variant in complex with glucosylglycerate
Descriptor: (2R)-2-(alpha-D-glucopyranosyloxy)-3-hydroxypropanoic acid, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
Authors:Cereija, T.B, Macedo-Ribeiro, S, Pereira, P.J.B.
Deposit date:2017-07-24
Release date:2018-08-08
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.17 Å)
Cite:The structural characterization of a glucosylglycerate hydrolase provides insights into the molecular mechanism of mycobacterial recovery from nitrogen starvation.
Iucrj, 6, 2019
5OIE
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BU of 5oie by Molmil
Crystal structure of Mycolicibacterium hassiacum glucosylglycerate hydrolase (MhGgH) E419A variant in complex with serine and glycerol
Descriptor: DI(HYDROXYETHYL)ETHER, GLYCEROL, SERINE, ...
Authors:Cereija, T.B, Macedo-Ribeiro, S, Pereira, P.J.B.
Deposit date:2017-07-18
Release date:2018-08-08
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.071 Å)
Cite:The structural characterization of a glucosylglycerate hydrolase provides insights into the molecular mechanism of mycobacterial recovery from nitrogen starvation.
Iucrj, 6, 2019
5OIV
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BU of 5oiv by Molmil
Crystal structure of Mycolicibacterium hassiacum glucosylglycerate hydrolase (MhGgH) D43A variant in complex with serine and glycerol
Descriptor: GLYCEROL, GLYCINE, Hydrolase, ...
Authors:Cereija, T.B, Macedo-Ribeiro, S, Pereira, P.J.B.
Deposit date:2017-07-19
Release date:2018-08-08
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.783 Å)
Cite:The structural characterization of a glucosylglycerate hydrolase provides insights into the molecular mechanism of mycobacterial recovery from nitrogen starvation.
Iucrj, 6, 2019
4V7L
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BU of 4v7l by Molmil
The structures of viomycin bound to the 70S ribosome.
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Stanley, R.E, Blaha, G.
Deposit date:2009-11-12
Release date:2014-07-09
Last modified:2018-07-11
Method:X-RAY DIFFRACTION (3 Å)
Cite:The structures of the anti-tuberculosis antibiotics viomycin and capreomycin bound to the 70S ribosome.
Nat.Struct.Mol.Biol., 17, 2010
4V7M
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BU of 4v7m by Molmil
The structures of Capreomycin bound to the 70S ribosome.
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Stanley, R.E, Blaha, G.
Deposit date:2009-11-12
Release date:2014-07-09
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (3.45 Å)
Cite:The structures of the anti-tuberculosis antibiotics viomycin and capreomycin bound to the 70S ribosome.
Nat.Struct.Mol.Biol., 17, 2010
6E3D
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BU of 6e3d by Molmil
Atomic structure of Mycobacterium tuberculosis DppA
Descriptor: Periplasmic dipeptide-binding lipoprotein DPPA, tetra-peptide picked up from the expression host
Authors:Ko, Y, Mitra, A, Niederweis, M, Cingolani, G.
Deposit date:2018-07-13
Release date:2019-09-11
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.271 Å)
Cite:Heme and hemoglobin utilization by Mycobacterium tuberculosis.
Nat Commun, 10, 2019
5CJ5
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BU of 5cj5 by Molmil
Structure of Mycobacterium thermoresistibile GlgE APO form at 3.13A resolution
Descriptor: Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase
Authors:Mendes, V, Blaszczyk, M, Maranha, A, Empadinhas, N, Blundell, T.L.
Deposit date:2015-07-13
Release date:2015-12-09
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.13 Å)
Cite:Structure of Mycobacterium thermoresistibile GlgE defines novel conformational states that contribute to the catalytic mechanism.
Sci Rep, 5, 2015
5CGM
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BU of 5cgm by Molmil
Structure of Mycobacterium thermoresistibile GlgE in complex with maltose at 1.95A resolution
Descriptor: 1,2-ETHANEDIOL, Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase, CHLORIDE ION, ...
Authors:Mendes, V, Blaszczyk, M, Maranha, A, Empadinhas, N, Blundell, T.L.
Deposit date:2015-07-09
Release date:2015-12-09
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structure of Mycobacterium thermoresistibile GlgE defines novel conformational states that contribute to the catalytic mechanism.
Sci Rep, 5, 2015
5CIM
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BU of 5cim by Molmil
Structure of Mycobacterium thermoresistibile GlgE in complex with maltose (cocrystallisation with maltose-1-phosphate) at 3.32A resolution
Descriptor: Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
Authors:Mendes, V, Blaszczyk, M, Maranha, A, Empadinhas, N, Blundell, T.L.
Deposit date:2015-07-13
Release date:2015-12-09
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.32 Å)
Cite:Structure of Mycobacterium thermoresistibile GlgE defines novel conformational states that contribute to the catalytic mechanism.
Sci Rep, 5, 2015

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数据于2024-09-25公开中

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