8ZMY
| F0502B-bound WT polymorph 5a alpha-synuclein fibril | Descriptor: | 2-bromanyl-4-[(~{E})-2-[6-[2-(2-fluoranylethoxy)ethyl-methyl-amino]-5-methyl-1,3-benzothiazol-2-yl]ethenyl]phenol, Alpha-synuclein | Authors: | Liu, K.E, Tao, Y.Q, Li, D, Liu, C. | Deposit date: | 2024-05-24 | Release date: | 2024-09-11 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Binding adaptability of chemical ligands to polymorphic alpha-synuclein amyloid fibrils. Proc.Natl.Acad.Sci.USA, 121, 2024
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8YFN
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9F4O
| UP1 in complex with Z991506900 | Descriptor: | (3~{R})-3-methyl-1-(6-methylpyridin-2-yl)piperazine, Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed | Authors: | Dunnett, L, Prischi, F. | Deposit date: | 2024-04-28 | Release date: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Enhanced identification of small molecules binding to hnRNP A1 via in silico hotspot and cryptic pockets mapping coupled with X-Ray fragment screening To Be Published
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9F55
| UP1 in complex with Z235361315 | Descriptor: | Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed, ~{N}-(3-azanyl-2-methyl-phenyl)propanamide | Authors: | Dunnett, L, Prischi, F. | Deposit date: | 2024-04-28 | Release date: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Enhanced identification of small molecules binding to hnRNP A1 via in silico hotspot and cryptic pockets mapping coupled with X-Ray fragment screening To Be Published
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8ZLP
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8YFM
| Crystal structure of FIP200 claw/TNIP1_FIR_pS122 | Descriptor: | GLYCEROL, RB1-inducible coiled-coil protein 1, SULFATE ION, ... | Authors: | Lv, M.Q, Wu, S.M. | Deposit date: | 2024-02-24 | Release date: | 2024-08-14 | Last modified: | 2024-08-28 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structural basis for TNIP1 binding to FIP200 during mitophagy. J.Biol.Chem., 300, 2024
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9EM9
| Structure of SynDLP MGD with GMPPNP | Descriptor: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Slr0869 protein | Authors: | Junglas, B, Gewehr, L, Schoennenbeck, P, Schneider, D, Sachse, C. | Deposit date: | 2024-03-07 | Release date: | 2024-09-11 | Method: | ELECTRON MICROSCOPY (3.76 Å) | Cite: | Structural basis for GTPase activity and conformational changes of the bacterial dynamin-like protein SynDLP. Cell Rep, 43, 2024
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9F4Y
| UP1 in complex with Z90120418 | Descriptor: | 1-(3,4,5-trimethoxyphenyl)methanamine, Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed | Authors: | Dunnett, L, Prischi, F. | Deposit date: | 2024-04-28 | Release date: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Enhanced identification of small molecules binding to hnRNP A1 via in silico hotspot and cryptic pockets mapping coupled with X-Ray fragment screening To Be Published
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8X99
| Cryo-EM structure of coxsackievirus A16 A-particle in complex with Fab h1A6.2 | Descriptor: | Capsid protein VP1, Capsid protein VP2, Capsid protein VP3 | Authors: | Jiang, Y, Huang, Y, Zhu, R, Zheng, Q, Li, S, Xia, N. | Deposit date: | 2023-11-29 | Release date: | 2024-09-04 | Method: | ELECTRON MICROSCOPY (3.38 Å) | Cite: | Cryo-EM structure of coxsackievirus A16 A-particle in complex with Fab h1A6.2 To Be Published
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4V6Y
| E. coli 70S-fMetVal-tRNAVal-tRNAfMet complex in classic pre-translocation state (pre1a) | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Blau, C, Bock, L.V, Schroder, G.F, Davydov, I, Fischer, N, Stark, H, Rodnina, M.V, Vaiana, A.C, Grubmuller, H. | Deposit date: | 2013-10-14 | Release date: | 2014-07-09 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (12 Å) | Cite: | Energy barriers and driving forces in tRNA translocation through the ribosome. Nat.Struct.Mol.Biol., 20, 2013
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9F5E
| UP1 in complex with Z30820160 | Descriptor: | Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed, N-(4-methyl-1,3-thiazol-2-yl)propanamide | Authors: | Dunnett, L, Prischi, F. | Deposit date: | 2024-04-28 | Release date: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Enhanced identification of small molecules binding to hnRNP A1 via in silico hotspot and cryptic pockets mapping coupled with X-Ray fragment screening To Be Published
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8ZSB
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9EP4
| Structure of Integrator subcomplex INTS5/8/15 | Descriptor: | Integrator complex subunit 15, Integrator complex subunit 5, Integrator complex subunit 8 | Authors: | Razew, M, Galej, W.P. | Deposit date: | 2024-03-17 | Release date: | 2024-06-12 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structural basis of the Integrator complex assembly and association with transcription factors. Mol.Cell, 84, 2024
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9B33
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9EP1
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8YBR
| Choline transporter BetT | Descriptor: | BCCT family transporter | Authors: | Yang, T.J, Nian, Y.W, Lin, H.J, Li, J, Zhang, J.R, Fan, M.R. | Deposit date: | 2024-02-16 | Release date: | 2024-09-04 | Method: | ELECTRON MICROSCOPY (2.57 Å) | Cite: | Structure and mechanism of the osmoregulated choline transporter BetT. Sci Adv, 10, 2024
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9FA7
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7TAA
| FAMILY 13 ALPHA AMYLASE IN COMPLEX WITH ACARBOSE | Descriptor: | CALCIUM ION, MODIFIED ACARBOSE HEXASACCHARIDE, TAKA AMYLASE | Authors: | Davies, G.J, Brzozowski, A.M. | Deposit date: | 1997-10-06 | Release date: | 1998-11-25 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.98 Å) | Cite: | Structure of the Aspergillus oryzae alpha-amylase complexed with the inhibitor acarbose at 2.0 A resolution. Biochemistry, 36, 1997
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9EO5
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4V91
| Kluyveromyces lactis 80S ribosome in complex with CrPV-IRES | Descriptor: | 25S RRNA, 5.8S RRNA, 5S RRNA, ... | Authors: | Fernandez, I.S, Bai, X, Scheres, S.H.W, Ramakrishnan, V. | Deposit date: | 2014-03-21 | Release date: | 2014-07-09 | Last modified: | 2019-12-11 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Initiation of Translation by Cricket Paralysis Virus Ires Requires its Translocation in the Ribosome. Cell(Cambridge,Mass.), 157, 2014
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9AU3
| Crystal structure of GenB2 in complex with G418 | Descriptor: | 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, 6'-epimerase, C-6' aminotransferase, ... | Authors: | De Oliveira, G.S, Bury, P.S, Huang, F, Li, Y, Araujo, N.C, Zhou, J, Sun, Y, Leeper, F, Leadlay, P, Dias, M.V.B. | Deposit date: | 2024-02-28 | Release date: | 2024-09-11 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Structural and Functional Basis of GenB2 Isomerase Activity from Gentamicin Biosynthesis. Acs Chem.Biol., 2024
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9FA4
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9BUV
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9F4R
| UP1 in complex with Z802821712 | Descriptor: | Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed, N-ethyl-6-methylpyridazin-3-amine | Authors: | Dunnett, L, Prischi, F. | Deposit date: | 2024-04-28 | Release date: | 2024-05-15 | Method: | X-RAY DIFFRACTION (1.59 Å) | Cite: | Enhanced identification of small molecules binding to hnRNP A1 via in silico hotspot and cryptic pockets mapping coupled with X-Ray fragment screening To Be Published
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9EZ8
| Cryo-EM structure of the icosahedral lumazine synthase from Vicia faba. | Descriptor: | 6,7-dimethyl-8-ribityllumazine synthase | Authors: | Chee, M, Trapani, S, Hoh, F, Lai Kee Him, J, Yvon, M, Blanc, S, Bron, P. | Deposit date: | 2024-04-11 | Release date: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Cryo-EM structure of the icosahedral lumazine synthase from Vicia faba. To Be Published
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