PDB: 20635 resultsInfo pagesStatus searchChemie searchBIRD

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2NPC	An unusual twin-His arrangement in the pore of ammonia channels is essential for substrate conductance Descriptor: ACETATE ION, Ammonia channel, IMIDAZOLE Authors: Lupo, D, Winkler, F.K. Deposit date: 2006-10-27 Release date: 2006-11-14 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.1 Å) Cite: An unusual twin-his arrangement in the pore of ammonia channels is essential for substrate conductance J.Biol.Chem., 281, 2006
2NPK	An unusual twin-His arrangement in the pore of ammonia channels is essential for substrate conductance Descriptor: ACETATE ION, Ammonia channel, GLYCEROL, ... Authors: Lupo, D, Winkler, F.K. Deposit date: 2006-10-27 Release date: 2006-11-14 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2 Å) Cite: An unusual twin-his arrangement in the pore of ammonia channels is essential for substrate conductance J.Biol.Chem., 281, 2006
2NPJ	An unusual twin-His arrangement in the pore of ammonia channels is essential for substrate conductance Descriptor: ACETATE ION, Ammonia channel, IMIDAZOLE Authors: Lupo, D, Winkler, F.K. Deposit date: 2006-10-27 Release date: 2006-11-14 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2 Å) Cite: An unusual twin-his arrangement in the pore of ammonia channels is essential for substrate conductance J.Biol.Chem., 281, 2006
2NOP	An unusual twin-His arrangement in the pore of ammonia channels is essential for substrate conductance Descriptor: ACETATE ION, Ammonia channel, GLYCEROL, ... Authors: Lupo, D, Winkler, F.K. Deposit date: 2006-10-26 Release date: 2006-11-14 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2 Å) Cite: An unusual twin-his arrangement in the pore of ammonia channels is essential for substrate conductance J.Biol.Chem., 281, 2006
2NPG	An unusual twin-His arrangement in the pore of ammonia channels is essential for substrate conductance Descriptor: ACETATE ION, Ammonia channel, GLYCEROL, ... Authors: Lupo, D, Winkler, F.K. Deposit date: 2006-10-27 Release date: 2006-11-14 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2 Å) Cite: An unusual twin-his arrangement in the pore of ammonia channels is essential for substrate conductance J.Biol.Chem., 281, 2006
6BFE	BACE crystal structure with hydroxy pyrrolidine inhibitor Descriptor: Beta-secretase 1, GLYCEROL, N-[(1R,2S)-1-[(2R,4R)-4-(cyclohexylmethoxy)pyrrolidin-2-yl]-3-(3,5-difluorophenyl)-1-hydroxypropan-2-yl]acetamide Authors: Timm, D.E. Deposit date: 2017-10-26 Release date: 2017-11-15 Last modified: 2017-12-27 Method: X-RAY DIFFRACTION (1.51 Å) Cite: Optimization of Hydroxyethylamine Transition State Isosteres as Aspartic Protease Inhibitors by Exploiting Conformational Preferences. J. Med. Chem., 60, 2017
6BFD	BACE crystal structure with hydroxy pyrrolidine inhibitor Descriptor: 2-{[(2S)-butan-2-yl]amino}-N-{(1R,2S)-1-hydroxy-3-phenyl-1-[(2R)-pyrrolidin-2-yl]propan-2-yl}-6-(methylsulfonyl)pyridine-4-carboxamide, Beta-secretase 1, GLYCEROL Authors: Timm, D.E. Deposit date: 2017-10-26 Release date: 2017-11-15 Last modified: 2017-12-27 Method: X-RAY DIFFRACTION (1.62 Å) Cite: Optimization of Hydroxyethylamine Transition State Isosteres as Aspartic Protease Inhibitors by Exploiting Conformational Preferences. J. Med. Chem., 60, 2017
6BFW	BACE crystal structure with hydroxy morpholine inhibitor Descriptor: Beta-secretase 1, GLYCEROL, N-[(1S,2S)-1-[(3R,6R)-6-(cyclohexylmethoxy)morpholin-3-yl]-3-(3,5-difluorophenyl)-1-hydroxypropan-2-yl]acetamide Authors: Timm, D.E. Deposit date: 2017-10-27 Release date: 2017-11-15 Last modified: 2017-12-27 Method: X-RAY DIFFRACTION (1.84 Å) Cite: Optimization of Hydroxyethylamine Transition State Isosteres as Aspartic Protease Inhibitors by Exploiting Conformational Preferences. J. Med. Chem., 60, 2017
6BFX	BACE crystal structure with hydroxy pyrrolidine inhibitor Descriptor: Beta-secretase 1, GLYCEROL, N-{(1S,2S)-3-(3,5-difluorophenyl)-1-[(3R,5S,6R)-6-(2,2-dimethylpropoxy)-5-methylmorpholin-3-yl]-1-hydroxypropan-2-yl}acetamide Authors: Timm, D.E. Deposit date: 2017-10-27 Release date: 2017-11-15 Last modified: 2017-12-27 Method: X-RAY DIFFRACTION (1.99 Å) Cite: Optimization of Hydroxyethylamine Transition State Isosteres as Aspartic Protease Inhibitors by Exploiting Conformational Preferences. J. Med. Chem., 60, 2017
4UX9	Crystal structure of JNK1 bound to a MKK7 docking motif Descriptor: DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 7, MITOGEN-ACTIVATED PROTEIN KINASE 8, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... Authors: Kragelj, J, Palencia, A, Nanao, M.H, Maurin, D, Bouvignies, G, Blackledge, M, Ringkjobing-Jensen, M. Deposit date: 2014-08-20 Release date: 2015-03-25 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.34 Å) Cite: Structure and Dynamics of the Mkk7-Jnk Signaling Complex. Proc.Natl.Acad.Sci.USA, 112, 2015
3LTQ	Structure of Interleukin 1B solved by SAD using an inserted Lanthanide Binding Tag Descriptor: ACETATE ION, Interleukin-1 beta, SULFATE ION, ... Authors: Peisach, E, Allen, K.N. Deposit date: 2010-02-16 Release date: 2011-02-16 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Engineering encodable lanthanide-binding tags into loop regions of proteins. J.Am.Chem.Soc., 133, 2011
7STA	X-ray Crystal Structure of Truncated Human Chemokine CCL19 (7-70) Descriptor: C-C motif chemokine 19 Authors: Lewandowski, E.M, Kroeck, K, Chen, Y. Deposit date: 2021-11-12 Release date: 2022-02-23 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Structural Insights into Molecular Recognition by Human Chemokine CCL19. Biochemistry, 61, 2022
4G6M	Crystal structure of human IL-1beta in complex with therapeutic antibody binding fragment of gevokizumab Descriptor: Interleukin-1 beta, heavy chain of gevokizumab antibody binding fragment, light chain of gevokizumab antibody binding fragment Authors: Blech, M, Hoerer, S. Deposit date: 2012-07-19 Release date: 2012-12-19 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.81 Å) Cite: Crystal structure of human IL-1beta in complex with therapeutic antibody binding fragment of gevokizumab J.Mol.Biol., 425, 2013
4G6K	Crystal structure of the therapeutic antibody binding fragment of gevokizumab in its unbound state Descriptor: heavy chain of gevokizumab antibody binding fragment, light chain of gevokizumab antibody binding fragment Authors: Blech, M, Hoerer, S. Deposit date: 2012-07-19 Release date: 2012-12-19 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.9 Å) Cite: One target-two different binding modes: Structural insights into gevokizumab and canakinumab interactions to interleukin-1beta J.Mol.Biol., 425, 2013
4PBD	Crystal structure of the N-terminal CS domain of human Shq1 Descriptor: Protein SHQ1 homolog Authors: Singh, M, Wang, Z, Cascio, D, Feigon, J. Deposit date: 2014-04-12 Release date: 2015-01-14 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (1.68 Å) Cite: Structure and Interactions of the CS Domain of Human H/ACA RNP Assembly Protein Shq1. J.Mol.Biol., 427, 2015
4PCK	Crystal structure of the P22S mutant of N-terminal CS domain of human Shq1 Descriptor: GLYCEROL, Protein SHQ1 homolog Authors: Singh, M, Wang, Z, Cascio, D, Feigon, J. Deposit date: 2014-04-15 Release date: 2015-01-14 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.401 Å) Cite: Structure and Interactions of the CS Domain of Human H/ACA RNP Assembly Protein Shq1. J.Mol.Biol., 427, 2015
8IGD	The crystal structure of the minimal interaction domains of DRB7.2:DRB4 complex Descriptor: Double-stranded RNA-binding domain (DsRBD)-containing protein, Double-stranded RNA-binding protein 4 Authors: Paturi, S, Deshmukh, M.V. Deposit date: 2023-02-20 Release date: 2024-06-26 Method: X-RAY DIFFRACTION (2.9 Å) Cite: The mechanism of the DRB7.2:DRB4 mediated endogenous inverted-repeat dsRNA (endo-IR dsRNA) sequestering in plants To Be Published
3LNY	Second PDZ domain from human PTP1E in complex with RA-GEF2 peptide Descriptor: Rap guanine nucleotide exchange factor 6, SULFATE ION, THIOCYANATE ION, ... Authors: Zhang, J, Chang, A, Ke, H, Phillips Jr, G.N, Lee, A.L, Center for Eukaryotic Structural Genomics (CESG) Deposit date: 2010-02-03 Release date: 2010-03-23 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.3 Å) Cite: Crystallographic and nuclear magnetic resonance evaluation of the impact of peptide binding to the second PDZ domain of protein tyrosine phosphatase 1E. Biochemistry, 49, 2010
3VQ5	HIV-1 IN core domain in complex with N-METHYL-1-(4-METHYL-2-PHENYL-1,3-THIAZOL-5-YL)METHANAMINE Descriptor: CADMIUM ION, CHLORIDE ION, N-methyl-1-(4-methyl-2-phenyl-1,3-thiazol-5-yl)methanamine, ... Authors: Wielens, J, Chalmers, D.K, Parker, M.W, Scanlon, M.J. Deposit date: 2012-03-20 Release date: 2013-01-30 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Parallel screening of low molecular weight fragment libraries: do differences in methodology affect hit identification? J Biomol Screen, 18, 2013
3VQ4	Fragments bound to HIV-1 integrase Descriptor: (5-phenyl-1,2-oxazol-3-yl)methanol, CADMIUM ION, POL polyprotein, ... Authors: Wielens, J, Chalmers, D.K, Parker, M.W, Scanlon, M.J. Deposit date: 2012-03-20 Release date: 2013-01-30 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Parallel screening of low molecular weight fragment libraries: do differences in methodology affect hit identification? J Biomol Screen, 18, 2013
3VQ6	HIV-1 IN core domain in complex with (1-methyl-5-phenyl-1H-pyrazol-4-yl)methanol Descriptor: (1-methyl-5-phenyl-1H-pyrazol-4-yl)methanol, CADMIUM ION, POL polyprotein, ... Authors: Wielens, J, Chalmers, D.K, Parker, M.W, Scanlon, M.J. Deposit date: 2012-03-20 Release date: 2013-01-30 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Parallel screening of low molecular weight fragment libraries: do differences in methodology affect hit identification? J Biomol Screen, 18, 2013
6VJB	Crystal structure of a catalytically inactive CXC Chemokine-degrading protease SpyCEP from Streptococcus pyogenes Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, Putative cell envelope proteinase Authors: Malito, E, Rouse, S. Deposit date: 2020-01-15 Release date: 2020-04-15 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.24 Å) Cite: Structure, dynamics and immunogenicity of a catalytically inactive CXC chemokine-degrading protease SpyCEP from Streptococcus pyogenes. Comput Struct Biotechnol J, 18, 2020
5HLK	Crystal structure of the ternary EcoRV-DNA-Lu complex with cleaved DNA substrate. Descriptor: 1,2-ETHANEDIOL, DNA (5'-D(*AP*AP*AP*GP*AP*TP)-3'), DNA (5'-D(*AP*TP*CP*TP*TP*TP)-3'), ... Authors: Sangani, S.S, Kehr, A.D, Sinha, K, Rule, G.S, Jen-Jacobson, L. Deposit date: 2016-01-15 Release date: 2016-11-09 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2 Å) Cite: Metal Ion Binding at the Catalytic Site Induces Widely Distributed Changes in a Sequence Specific Protein-DNA Complex. Biochemistry, 55, 2016
5AUI	Crystal structure of Ferredoxin from Thermosynechococcus elongatus Descriptor: BENZAMIDINE, FE2/S2 (INORGANIC) CLUSTER, Ferredoxin-1 Authors: Kurisu, G, Shinmura, K. Deposit date: 2015-04-21 Release date: 2015-09-23 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.499 Å) Cite: X-ray Structure and Nuclear Magnetic Resonance Analysis of the Interaction Sites of the Ga-Substituted Cyanobacterial Ferredoxin Biochemistry, 54, 2015
5AUK	Crystal structure of the Ga-substituted Ferredoxin Descriptor: BENZAMIDINE, Ferredoxin-1, SULFATE ION, ... Authors: Kurisu, G, Muraki, N, Taya, M, Hase, T. Deposit date: 2015-04-24 Release date: 2015-09-23 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.62 Å) Cite: X-ray Structure and Nuclear Magnetic Resonance Analysis of the Interaction Sites of the Ga-Substituted Cyanobacterial Ferredoxin Biochemistry, 54, 2015

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