2WE4
| Carbamate kinase from Enterococcus faecalis bound to a sulfate ion and two water molecules, which mimic the substrate carbamyl phosphate | Descriptor: | CARBAMATE KINASE 1, SULFATE ION | Authors: | Ramon-Maiques, S, Marina, A, Gil-Ortiz, F, Rubio, V. | Deposit date: | 2009-03-27 | Release date: | 2010-03-16 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.02 Å) | Cite: | Substrate Binding and Catalysis in Carbamate Kinase Ascertained by Crystallographic and Site-Directed Mutagenesis Studies. Movements and Significance of a Unique Globular Subdomain of This Key Enzyme for Fermentative ATP Production in Bacteria. J.Mol.Biol., 397, 2010
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3ZFQ
| Crystal structure of product-like, processed N-terminal protease Npro with mercury | Descriptor: | MERCURY (II) ION, MONOTHIOGLYCEROL, N-TERMINAL PROTEASE NPRO | Authors: | Zogg, T, Sponring, M, Schindler, S, Koll, M, Schneider, R, Brandstetter, H, Auer, B. | Deposit date: | 2012-12-12 | Release date: | 2013-05-15 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Crystal Structures of the Viral Protease Npro Imply Distinct Roles for the Catalytic Water in Catalysis Structure, 21, 2013
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7D4B
| Crystal structure of 4-1BB in complex with a VHH | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | Authors: | Wang, C. | Deposit date: | 2020-09-23 | Release date: | 2021-07-14 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.14 Å) | Cite: | Generation of a safe and efficacious llama single-domain antibody fragment (vHH) targeting the membrane-proximal region of 4-1BB for engineering therapeutic bispecific antibodies for cancer. J Immunother Cancer, 9, 2021
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7CZD
| Crystal structure of PD-L1 in complex with a VHH | Descriptor: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Programmed cell death 1 ligand 1, ... | Authors: | Wang, C. | Deposit date: | 2020-09-08 | Release date: | 2021-07-14 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.64 Å) | Cite: | Generation of a safe and efficacious llama single-domain antibody fragment (vHH) targeting the membrane-proximal region of 4-1BB for engineering therapeutic bispecific antibodies for cancer. J Immunother Cancer, 9, 2021
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7DDM
| Crystal Structure of PenA39 beta-Lactamase | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, ALA-ALA-ARG-ASP-ALA-ALA-VAL-SER-ASP-ALA-ALA-ALA, ... | Authors: | Nukaga, M, Hoshino, T, Papp-Wallace, K.M. | Deposit date: | 2020-10-29 | Release date: | 2021-11-03 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Frameshift mutations in genes encoding PBP3 and PBP4 trigger an unusual, extreme beta-lactam resistance phenotype in Burkholderia multivorans To Be Published
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4APX
| CRYSTAL STRUCTURE OF MOUSE CADHERIN-23 EC1-2 AND PROTOCADHERIN-15 EC1- 2 FORM I | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CADHERIN-23, CALCIUM ION, ... | Authors: | Sotomayor, M, Weihofen, W, Gaudet, R, Corey, D.P. | Deposit date: | 2012-04-07 | Release date: | 2012-11-07 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Structure of a Force-Conveying Cadherin Bond Essential for Inner-Ear Mechanotransduction Nature, 492, 2012
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2WE5
| Carbamate kinase from Enterococcus faecalis bound to MgADP | Descriptor: | ACETATE ION, ADENOSINE-5'-DIPHOSPHATE, CARBAMATE KINASE 1, ... | Authors: | Ramon-Maiques, S, Marina, A, Rubio, V. | Deposit date: | 2009-03-27 | Release date: | 2010-03-16 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.39 Å) | Cite: | Substrate Binding and Catalysis in Carbamate Kinase Ascertained by Crystallographic and Site- Directed Mutagenesis Studies. Movements and Significance of a Unique Globular Subdomain of This Key Enzyme for Fermentative ATP Production in Bacteria. J.Mol.Biol., 397, 2010
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2W8H
| Crystal structure of spin labeled Wza24-345. | Descriptor: | CHLORIDE ION, PUTATIVE OUTER MEMBRANE LIPOPROTEIN WZA, S-[(1-oxyl-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-yl)methyl] methanesulfonothioate | Authors: | Hagelueken, G, Ingledew, W.J, Huang, H, Petrovic-Stojanovska, B, Whitfield, C, ElMkami, H, Schiemann, O, Naismith, J.H. | Deposit date: | 2009-01-16 | Release date: | 2009-02-10 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.76 Å) | Cite: | Peldor Distance Fingerprinting of the Octameric Outer-Membrane Protein Wza from Escherichia Coli. Angew.Chem.Int.Ed.Engl., 48, 2009
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4A2B
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1Y7K
| NMR structure family of Human Agouti Signalling Protein (80-132: Q115Y, S124Y) | Descriptor: | Agouti Signaling Protein | Authors: | McNulty, J.C, Jackson, P.J, Thompson, D.A, Chai, B, Gantz, I, Barsh, G.S, Dawson, P.E, Millhauser, G.L. | Deposit date: | 2004-12-08 | Release date: | 2005-02-15 | Last modified: | 2021-10-20 | Method: | SOLUTION NMR | Cite: | Structures of the agouti signaling protein. J.Mol.Biol., 346, 2005
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7AMR
| Crystal structure of the complex of the KFN mutant of Jovi-1 Fab with human TRBC1 | Descriptor: | CHLORIDE ION, GLYCEROL, Human Jovi-1 Fab fragment, ... | Authors: | Ferrari, M, Bulek, A, Bughda, R, Jha, R, Welin, M, Logan, D.T, Sewell, A, Onuoha, S, Pule, M. | Deposit date: | 2020-10-09 | Release date: | 2022-04-20 | Last modified: | 2022-04-27 | Method: | X-RAY DIFFRACTION (1.949 Å) | Cite: | Structure-Guided Engineering of Immunotherapies Targeting TRBC1 and TRBC2 in T Cell Malignancies Res Sq, 2022
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2VER
| Structural model for the complex between the Dr adhesins and carcinoembryonic antigen (CEA) | Descriptor: | AFIMBRIAL ADHESIN AFA-III, ARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 5, S-[(1-oxyl-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-yl)methyl] methanesulfonothioate | Authors: | Korotkova, N, Yang, Y, Le Trong, I, Cota, E, Demeler, B, Marchant, J, Thomas, W.E, Stenkamp, R.E, Moseley, S.L, Matthews, S. | Deposit date: | 2007-10-26 | Release date: | 2008-01-08 | Last modified: | 2011-07-13 | Method: | SOLUTION NMR | Cite: | Binding of Dr Adhesins of Escherichia Coli to Carcinoembryonic Antigen Triggers Receptor Dissociation. Mol.Microbiol., 67, 2008
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7BT8
| Mevo lectin complex with mannotriose | Descriptor: | 1,2-ETHANEDIOL, GLYCEROL, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose, ... | Authors: | Sivaji, N, Suguna, K, Surolia, A, Vijayan, M. | Deposit date: | 2020-03-31 | Release date: | 2021-02-03 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural and related studies on Mevo lectin from Methanococcus voltae A3: the first thorough characterization of an archeal lectin and its interactions. Glycobiology, 31, 2021
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3ZFR
| Crystal structure of product-like, processed N-terminal protease Npro with iridium | Descriptor: | HYDROXIDE ION, IRIDIUM (III) ION, MONOTHIOGLYCEROL, ... | Authors: | Zogg, T, Sponring, M, Schindler, S, Koll, M, Schneider, R, Brandstetter, H, Auer, B. | Deposit date: | 2012-12-12 | Release date: | 2013-05-15 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal Structures of the Viral Protease Npro Imply Distinct Roles for the Catalytic Water in Catalysis Structure, 21, 2013
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1Y7J
| NMR structure family of Human Agouti Signalling Protein (80-132: Q115Y, S124Y) | Descriptor: | Agouti Signaling Protein | Authors: | McNulty, J.C, Jackson, P.J, Thompson, D.A, Chai, B, Gantz, I, Barsh, G.S, Dawson, P.E, Millhauser, G.L. | Deposit date: | 2004-12-08 | Release date: | 2005-02-15 | Last modified: | 2021-10-20 | Method: | SOLUTION NMR | Cite: | Structures of the agouti signaling protein. J.Mol.Biol., 346, 2005
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1Q0K
| Crystal structure of Ni-containing superoxide dismutase with Ni-ligation corresponding to the thiosulfate-reduced state | Descriptor: | NICKEL (II) ION, SULFATE ION, Superoxide dismutase [Ni], ... | Authors: | Wuerges, J, Lee, J.-W, Yim, Y.-I, Yim, H.-S, Kang, S.-O, Djinovic Carugo, K. | Deposit date: | 2003-07-16 | Release date: | 2004-05-18 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structure of nickel-containing superoxide dismutase reveals another type of active site Proc.Natl.Acad.Sci.USA, 101, 2004
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2XE7
| The complete reaction cycle of human phosphoglycerate kinase: The open ternary complex with 3PG and ADP | Descriptor: | 3-PHOSPHOGLYCERIC ACID, ADENOSINE-5'-DIPHOSPHATE, PHOSPHOGLYCERATE KINASE 1 | Authors: | Cliff, M.J, Baxter, N.J, Blackburn, G.M, Merli, A, Vas, M, Waltho, J.P, Bowler, M.W. | Deposit date: | 2010-05-11 | Release date: | 2011-01-19 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | A Spring Loaded Release Mechanism Regulates Domain Movement and Catalysis in Phosphoglycerate Kinase. J.Biol.Chem., 286, 2011
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7E4R
| Crystal structure of tubulin in complex with D-DM1-SMe | Descriptor: | (10E,12E)-86-chloro-14-hydroxy-85,14-dimethoxy-33,2,7,10-tetramethyl-12,6-dioxo-7-aza-1(6,4)-oxazinana-3(2,3)-oxirana-8(1,3)-benzenacyclotetradecaphane-10,12-dien-4-yl N-methyl-N-(3-(methylsulfinothioyl)propanoyl)-D-alaninate, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... | Authors: | Wang, Y, Li, W. | Deposit date: | 2021-02-15 | Release date: | 2021-07-07 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.597 Å) | Cite: | C3 ester side chain plays a pivotal role in the antitumor activity of Maytansinoids. Biochem.Biophys.Res.Commun., 566, 2021
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2XE6
| The complete reaction cycle of human phosphoglycerate kinase: The open binary complex with 3PG | Descriptor: | 3-PHOSPHOGLYCERIC ACID, PHOSPHOGLYCERATE KINASE 1 | Authors: | Cliff, M.J, Baxter, N.J, Blackburn, G.M, Merli, A, Vas, M, Waltho, J.P, Bowler, M.W. | Deposit date: | 2010-05-11 | Release date: | 2011-01-19 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.74 Å) | Cite: | A Spring Loaded Release Mechanism Regulates Domain Movement and Catalysis in Phosphoglycerate Kinase. J.Biol.Chem., 286, 2011
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2XE8
| The complete reaction cycle of human phosphoglycerate kinase: The open ternary complex with 3PG and AMP-PNP | Descriptor: | 3-PHOSPHOGLYCERIC ACID, PHOSPHOGLYCERATE KINASE 1, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER | Authors: | Cliff, M.J, Baxter, N.J, Blackburn, G.M, Merli, A, Vas, M, Waltho, J.P, Bowler, M.W. | Deposit date: | 2010-05-11 | Release date: | 2011-01-19 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | A Spring Loaded Release Mechanism Regulates Domain Movement and Catalysis in Phosphoglycerate Kinase. J.Biol.Chem., 286, 2011
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3ZFP
| Crystal structure of product-like, processed N-terminal protease Npro with internal His-Tag | Descriptor: | CHLORIDE ION, MONOTHIOGLYCEROL, N-TERMINAL PROTEASE NPRO | Authors: | Zogg, T, Sponring, M, Schindler, S, Koll, M, Schneider, R, Brandstetter, H, Auer, B. | Deposit date: | 2012-12-12 | Release date: | 2013-05-15 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.25 Å) | Cite: | Crystal Structures of the Viral Protease Npro Imply Distinct Roles for the Catalytic Water in Catalysis Structure, 21, 2013
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7D8Q
| The structure of nucleotide phosphatase Sa1684 complex with GDP analogue from Staphylococcus aureus | Descriptor: | MAGNESIUM ION, UPF0374 protein SAB1800c, [(2R,3R,4S,5S)-5-(2-azanyl-6-oxidanyl-purin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl bis(oxidanyl)phosphinothioyl hydrogen phosphate | Authors: | Wang, Z, Li, X. | Deposit date: | 2020-10-09 | Release date: | 2021-03-17 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | The structural mechanism for the nucleoside tri- and diphosphate hydrolysis activity of Ntdp from Staphylococcus aureus. Febs J., 288, 2021
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3ZFT
| Crystal structure of product-like, processed N-terminal protease Npro at pH 3 | Descriptor: | CHLORIDE ION, MONOTHIOGLYCEROL, N-TERMINAL PROTEASE NPRO | Authors: | Zogg, T, Sponring, M, Schindler, S, Koll, M, Schneider, R, Brandstetter, H, Auer, B. | Deposit date: | 2012-12-12 | Release date: | 2013-05-15 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal Structures of the Viral Protease Npro Imply Distinct Roles for the Catalytic Water in Catalysis Structure, 21, 2013
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2V1Q
| Atomic-resolution structure of the yeast Sla1 SH3 domain 3 | Descriptor: | CHLORIDE ION, CYTOSKELETON ASSEMBLY CONTROL PROTEIN SLA1, PLATINUM (II) ION, ... | Authors: | Kursula, I, Kursula, P, Zou, P, Lehmann, F, Song, Y.H, Wilmanns, M. | Deposit date: | 2007-05-29 | Release date: | 2008-06-03 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Structural Genomics of Yeast SH3 Domains To be Published
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7E48
| Crystal structure of InhA in complex with 3-nitropropanoic acid inhibitor | Descriptor: | 3-NITROPROPANOIC ACID, Enoyl-[acyl-carrier-protein] reductase [NADH], GLYCEROL, ... | Authors: | Songsiriritthigul, C, Hanwarinroj, C, Suttipanta, N, Kamsri, P, Kittakoop, P, Pungpo, P. | Deposit date: | 2021-02-10 | Release date: | 2021-11-24 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Inhibition of Mycobacterium tuberculosis InhA by 3-nitropropanoic acid. Proteins, 90, 2022
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