7MFT
 
 | | Glutamate synthase, glutamate dehydrogenase counter-enzyme complex (GudB6-GltA6-GltB6) | | Descriptor: | FE3-S4 CLUSTER, FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, ... | | Authors: | Jayaraman, V, Lee, D.J, Elad, N, Fraser, J.S, Tawfik, D.S. | | Deposit date: | 2021-04-11 | | Release date: | 2022-01-05 | | Last modified: | 2024-05-29 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | A counter-enzyme complex regulates glutamate metabolism in Bacillus subtilis.
Nat.Chem.Biol., 18, 2022
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7MFM
 | | Glutamate synthase, glutamate dehydrogenase counter-enzyme complex | | Descriptor: | FE3-S4 CLUSTER, FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, ... | | Authors: | Jayaraman, V, Lee, D.J, Elad, N, Fraser, J.S, Tawfik, D.S. | | Deposit date: | 2021-04-10 | | Release date: | 2022-01-05 | | Last modified: | 2022-02-16 | | Method: | ELECTRON MICROSCOPY (2.42 Å) | | Cite: | A counter-enzyme complex regulates glutamate metabolism in Bacillus subtilis.
Nat.Chem.Biol., 18, 2022
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1NR1
 | | Crystal structure of the R463A mutant of human Glutamate dehydrogenase | | Descriptor: | Glutamate dehydrogenase 1 | | Authors: | Banerjee, S, Schmidt, T, Fang, J, Stanley, C.A, Smith, T.J. | | Deposit date: | 2003-01-23 | | Release date: | 2003-05-06 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Structural studies on ADP activation of mammalian glutamate dehydrogenase and the evolution of regulation
Biochemistry, 42, 2003
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3SBO
 | | Structure of E.coli GDH from native source | | Descriptor: | CHLORIDE ION, NADP-specific glutamate dehydrogenase | | Authors: | Gee, C.L, Zubieta, C, Echols, N, Totir, M. | | Deposit date: | 2011-06-06 | | Release date: | 2012-03-21 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (3.204 Å) | | Cite: | Macro-to-Micro Structural Proteomics: Native Source Proteins for High-Throughput Crystallization.
Plos One, 7, 2012
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4FCC
 | | Glutamate dehydrogenase from E. coli | | Descriptor: | Glutamate dehydrogenase | | Authors: | Bilokapic, S, Schwartz, T.U. | | Deposit date: | 2012-05-24 | | Release date: | 2012-09-26 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Molecular basis for Nup37 and ELY5/ELYS recruitment to the nuclear pore complex.
Proc.Natl.Acad.Sci.USA, 109, 2012
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3R3J
 | | Kinetic and structural characterization of Plasmodium falciparum glutamate dehydrogenase 2 | | Descriptor: | Glutamate dehydrogenase | | Authors: | Zocher, K, Fritz-Wolf, K, Kehr, S, Rahlfs, S, Becker, K. | | Deposit date: | 2011-03-16 | | Release date: | 2012-03-07 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Biochemical and structural characterization of Plasmodium falciparum glutamate dehydrogenase 2.
Mol.Biochem.Parasitol., 183, 2012
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4FHN
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6G2U
 | | Crystal structure of the human glutamate dehydrogenase 2 (hGDH2) | | Descriptor: | CHLORIDE ION, Glutamate dehydrogenase 2, mitochondrial, ... | | Authors: | Fadouloglou, V.F, Dimovasili, C, Providaki, M, Kotsifaki, D, Sarrou, I, Plaitakis, A, Zaganas, I, Kokkinidis, M. | | Deposit date: | 2018-03-23 | | Release date: | 2019-04-10 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.934287 Å) | | Cite: | Crystal structure of glutamate dehydrogenase 2, a positively selected novel human enzyme involved in brain biology and cancer pathophysiology.
J.Neurochem., 2021
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2YFQ
 | | Crystal structure of Glutamate dehydrogenase from Peptoniphilus asaccharolyticus | | Descriptor: | NAD-SPECIFIC GLUTAMATE DEHYDROGENASE, SULFATE ION | | Authors: | Oliveira, T, Panjikar, S, Carrigan, J.B, Sharkey, M.A, Hamza, M, Engel, P.C, Khan, A.R. | | Deposit date: | 2011-04-07 | | Release date: | 2011-11-23 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.94 Å) | | Cite: | Crystal Structure of Nad-Dependent Peptoniphilus Asaccharolyticus Glutamate Dehydrogenase Reveals Determinants of Cofactor Specificity.
J.Struct.Biol., 177, 2012
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3ETG
 | | Glutamate dehydrogenase complexed with GW5074 | | Descriptor: | (3E)-3-[(3,5-dibromo-4-hydroxyphenyl)methylidene]-5-iodo-1,3-dihydro-2H-indol-2-one, GLUTAMIC ACID, GUANOSINE-5'-TRIPHOSPHATE, ... | | Authors: | Li, M, Smith, T.J. | | Deposit date: | 2008-10-07 | | Release date: | 2009-06-09 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Novel Inhibitors Complexed with Glutamate Dehydrogenase: ALLOSTERIC REGULATION BY CONTROL OF PROTEIN DYNAMICS
J.Biol.Chem., 284, 2009
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3ETD
 | | Structure of glutamate dehydrogenase complexed with bithionol | | Descriptor: | 2,2'-sulfanediylbis(4,6-dichlorophenol), GLUD1 protein, GLUTAMIC ACID, ... | | Authors: | Li, M, Smith, T.J. | | Deposit date: | 2008-10-07 | | Release date: | 2009-06-09 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Novel Inhibitors Complexed with Glutamate Dehydrogenase: ALLOSTERIC REGULATION BY CONTROL OF PROTEIN DYNAMICS
J.Biol.Chem., 284, 2009
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1L1F
 | | Structure of human glutamate dehydrogenase-apo form | | Descriptor: | Glutamate Dehydrogenase 1 | | Authors: | Smith, T.J, Schmidt, T, Fang, J, Wu, J, Siuzdak, G, Stanley, C.A. | | Deposit date: | 2002-02-15 | | Release date: | 2002-03-06 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | The structure of apo human glutamate dehydrogenase details subunit communication and allostery.
J.Mol.Biol., 318, 2002
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1LEH
 | | LEUCINE DEHYDROGENASE FROM BACILLUS SPHAERICUS | | Descriptor: | LEUCINE DEHYDROGENASE | | Authors: | Baker, P.J, Turnbull, A.P, Sedelnikova, S.E, Stillman, T.J, Rice, D.W. | | Deposit date: | 1995-06-09 | | Release date: | 1996-12-23 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | A role for quaternary structure in the substrate specificity of leucine dehydrogenase.
Structure, 3, 1995
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7VDA
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7UZM
 | | Glutamate dehydrogenase 1 from human liver | | Descriptor: | Glutamate dehydrogenase 1, mitochondrial | | Authors: | Zhang, Z. | | Deposit date: | 2022-05-09 | | Release date: | 2023-05-03 | | Last modified: | 2023-11-15 | | Method: | ELECTRON MICROSCOPY (3.24 Å) | | Cite: | High-resolution structural-omics of human liver enzymes.
Cell Rep, 42, 2023
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7VID
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1K89
 | | K89L MUTANT OF GLUTAMATE DEHYDROGENASE | | Descriptor: | GLUTAMATE DEHYDROGENASE | | Authors: | Stillman, T.J, Migueis, A.M.B, Wang, X.G, Baker, P.J, Britton, K.L, Engel, P.C, Rice, D.W. | | Deposit date: | 1998-06-05 | | Release date: | 1999-01-27 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Insights into the mechanism of domain closure and substrate specificity of glutamate dehydrogenase from Clostridium symbiosum.
J.Mol.Biol., 285, 1999
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3ETE
 | | Crystal structure of bovine glutamate dehydrogenase complexed with hexachlorophene | | Descriptor: | 2,2'-methanediylbis(3,4,6-trichlorophenol), GLUTAMIC ACID, GUANOSINE-5'-TRIPHOSPHATE, ... | | Authors: | Li, M, Smith, T.J. | | Deposit date: | 2008-10-07 | | Release date: | 2009-06-09 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Novel Inhibitors Complexed with Glutamate Dehydrogenase: ALLOSTERIC REGULATION BY CONTROL OF PROTEIN DYNAMICS
J.Biol.Chem., 284, 2009
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3AOE
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3AOG
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7ECT
 | | Crystal Structure of Aspergillus terreus Glutamate Dehydrogenase (AtGDH) Complexed With Tartrate and NADPH | | Descriptor: | GLYCEROL, Glutamate dehydrogenase, L(+)-TARTARIC ACID, ... | | Authors: | Godsora, B.K.J, Prakash, P, Punekar, N.S, Bhaumik, P. | | Deposit date: | 2021-03-13 | | Release date: | 2021-12-08 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Molecular insights into the inhibition of glutamate dehydrogenase by the dicarboxylic acid metabolites.
Proteins, 90, 2022
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7ECR
 | | Crystal Structure of Aspergillus terreus Glutamate Dehydrogenase (AtGDH) Complexed With Succinate and ADP-ribose | | Descriptor: | GLYCEROL, Glutamate dehydrogenase, SUCCINIC ACID, ... | | Authors: | Godsora, B.K.J, Prakash, P, Punekar, N.S, Bhaumik, P. | | Deposit date: | 2021-03-13 | | Release date: | 2021-12-08 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.73 Å) | | Cite: | Molecular insights into the inhibition of glutamate dehydrogenase by the dicarboxylic acid metabolites.
Proteins, 90, 2022
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7ECS
 | | Crystal Structure of Aspergillus terreus Glutamate Dehydrogenase (AtGDH) Complexed With Malonate and NADPH | | Descriptor: | GLYCEROL, Glutamate dehydrogenase, MALONATE ION, ... | | Authors: | Godsora, B.K.J, Prakash, P, Punekar, N.S, Bhaumik, P. | | Deposit date: | 2021-03-13 | | Release date: | 2021-12-08 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.74 Å) | | Cite: | Molecular insights into the inhibition of glutamate dehydrogenase by the dicarboxylic acid metabolites.
Proteins, 90, 2022
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1EUZ
 | | GLUTAMATE DEHYDROGENASE FROM THERMOCOCCUS PROFUNDUS IN THE UNLIGATED STATE | | Descriptor: | GLUTAMATE DEHYDROGENASE, SULFATE ION | | Authors: | Nakasako, M. | | Deposit date: | 2000-04-19 | | Release date: | 2001-04-25 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | Large-scale domain movements and hydration structure changes in the active-site cleft of unligated glutamate dehydrogenase from Thermococcus profundus studied by cryogenic X-ray crystal structure analysis and small-angle X-ray scattering.
Biochemistry, 40, 2001
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1GTM
 | | STRUCTURE OF GLUTAMATE DEHYDROGENASE | | Descriptor: | GLUTAMATE DEHYDROGENASE, SULFATE ION | | Authors: | Yip, K.S.P, Stillman, T.J, Britton, K.L, Pasquo, A, Rice, D.W. | | Deposit date: | 1996-08-22 | | Release date: | 1997-01-11 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | The structure of Pyrococcus furiosus glutamate dehydrogenase reveals a key role for ion-pair networks in maintaining enzyme stability at extreme temperatures.
Structure, 3, 1995
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