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7LIR
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BU of 7lir by Molmil
Structure of the invertebrate ALK GRD
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ALK tyrosine kinase receptor homolog scd-2, ...
Authors:Stayrook, S, Li, T, Klein, D.E.
Deposit date:2021-01-27
Release date:2021-11-24
Last modified:2021-12-15
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis for ligand reception by anaplastic lymphoma kinase.
Nature, 600, 2021
6ZXM
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BU of 6zxm by Molmil
Diguanylate cyclase DgcR in complex with c-di-GMP
Descriptor: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), MAGNESIUM ION, Putative GGDEF/response regulator receiver domain protein
Authors:Teixeira, R.D, Schirmer, T.
Deposit date:2020-07-29
Release date:2021-03-31
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Activation mechanism of a small prototypic Rec-GGDEF diguanylate cyclase.
Nat Commun, 12, 2021
8VQ9
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BU of 8vq9 by Molmil
Prefusion stabilized structure of the SARS-CoV-2 fusion machinery
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S2
Authors:Lee, J, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2024-01-18
Release date:2024-07-24
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:A broadly generalizable stabilization strategy for sarbecovirus fusion machinery vaccines.
Nat Commun, 15, 2024
6R41
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BU of 6r41 by Molmil
Structure of P110 from Mycoplasma genitalium complexed with 3'SL
Descriptor: GLYCEROL, Mgp-operon protein 3, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose, ...
Authors:Aparicio, D, Fita, I.
Deposit date:2019-03-21
Release date:2019-05-08
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Mycoplasma genitalium adhesin P110 binds sialic-acid human receptors.
Nat Commun, 9, 2018
8VQB
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BU of 8vqb by Molmil
Prefusion stabilized structure of the SARS-CoV-2 fusion machinery
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S2
Authors:Lee, J, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2024-01-18
Release date:2024-07-24
Method:ELECTRON MICROSCOPY (3 Å)
Cite:A broadly generalizable stabilization strategy for sarbecovirus fusion machinery vaccines.
Nat Commun, 15, 2024
8VQA
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BU of 8vqa by Molmil
Prefusion stabilized structure of the SARS-CoV-2 fusion machinery
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S2
Authors:Lee, J, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2024-01-18
Release date:2024-07-24
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:A broadly generalizable stabilization strategy for sarbecovirus fusion machinery vaccines.
Nat Commun, 15, 2024
8VBY
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BU of 8vby by Molmil
Structure of the human dopamine transporter in complex with beta-CFT, MRS7292 and divalent zinc
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, DECANE, ...
Authors:Srivastava, D.K, Gouaux, E.
Deposit date:2023-12-12
Release date:2024-08-07
Last modified:2024-09-04
Method:ELECTRON MICROSCOPY (3.19 Å)
Cite:Structure of the human dopamine transporter and mechanisms of inhibition.
Nature, 632, 2024
4X98
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BU of 4x98 by Molmil
Immunoglobulin Fc heterodimer variant
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Ig gamma-1 chain C region
Authors:Seok, S.H, Choi, H.J, Kim, Y.J, Seo, M.D, Kim, Y.S.
Deposit date:2014-12-11
Release date:2015-06-03
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.499 Å)
Cite:Crystal structures of immunoglobulin Fc heterodimers reveal the molecular basis for heterodimer formation.
Mol.Immunol., 65, 2015
8CTE
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BU of 8cte by Molmil
Class 2 of erythrocyte ankyrin-1 complex (Composite map)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Ammonium transporter Rh type A, Ankyrin-1, ...
Authors:Vallese, F, Kim, K, Yen, L.Y, Johnston, J.D, Noble, A.J, Cali, T, Clarke, O.B.
Deposit date:2022-05-14
Release date:2022-07-20
Last modified:2022-07-27
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Architecture of the human erythrocyte ankyrin-1 complex.
Nat.Struct.Mol.Biol., 29, 2022
4X99
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BU of 4x99 by Molmil
Immunoglobulin Fc heterodimers variant
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Ig gamma-1 chain C region
Authors:Seok, S.H, Choi, H.J, Kim, Y.J, Seo, M.D, Kim, Y.S.
Deposit date:2014-12-11
Release date:2015-06-03
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.498 Å)
Cite:Crystal structures of immunoglobulin Fc heterodimers reveal the molecular basis for heterodimer formation.
Mol.Immunol., 65, 2015
8EG3
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BU of 8eg3 by Molmil
Structure of human placental steroid (estrone/DHEA) sulfatase at 2.0 angstrom resolution
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, PHOSPHATE ION, ...
Authors:Ghosh, D.
Deposit date:2022-09-10
Release date:2022-12-07
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Structure of human placental steroid sulfatase at 2.0 angstrom resolution: Catalysis, quaternary association, and a secondary ligand site.
J.Steroid Biochem.Mol.Biol., 227, 2022
8P36
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BU of 8p36 by Molmil
Neisseria meningitidis Type IV pilus SB-DATDH variant
Descriptor: 2,4-bisacetamido-2,4,6-trideoxy-beta-D-glucopyranose, Neisseria meningitidis PilE, SB-DATDH variant, ...
Authors:Fernandez-Martinez, D, Dumenil, G.
Deposit date:2023-05-17
Release date:2024-04-03
Method:ELECTRON MICROSCOPY (2.51 Å)
Cite:Cryo-EM structures of type IV pili complexed with nanobodies reveal immune escape mechanisms.
Nat Commun, 15, 2024
7R3K
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BU of 7r3k by Molmil
Chlamydomonas reinhardtii TSP9 mutant small Photosystem I complex
Descriptor: (1~{S})-3,5,5-trimethyl-4-[(1~{E},3~{E},5~{E},7~{E},9~{E},11~{E},13~{E},15~{E},17~{E})-3,7,12,16-tetramethyl-18-[(4~{S})-2,6,6-trimethyl-4-oxidanyl-cyclohexen-1-yl]octadeca-1,3,5,7,9,11,13,15,17-nonaenyl]cyclohex-3-en-1-ol, (3R)-beta,beta-caroten-3-ol, (3R,3'R,6S)-4,5-DIDEHYDRO-5,6-DIHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, ...
Authors:Klaiman, D, Schwartz, T, Nelson, N.
Deposit date:2022-02-07
Release date:2023-02-22
Last modified:2023-04-12
Method:ELECTRON MICROSCOPY (2.52 Å)
Cite:Structure of Photosystem I Supercomplex Isolated from a Chlamydomonas reinhardtii Cytochrome b6f Temperature-Sensitive Mutant.
Biomolecules, 13, 2023
6G9X
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BU of 6g9x by Molmil
Crystal structure of a MFS transporter at 2.54 Angstroem resolution
Descriptor: 2-sulfanylbenzoic acid, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, MERCURY (II) ION, ...
Authors:Kalbermatter, D, Bosshart, P, Bonetti, S, Fotiadis, D.
Deposit date:2018-04-11
Release date:2019-07-03
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Mechanistic basis of L-lactate transport in the SLC16 solute carrier family.
Nat Commun, 10, 2019
5ESZ
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BU of 5esz by Molmil
Crystal Structure of Broadly Neutralizing Antibody CH04, Isolated from Donor CH0219, in Complex with Scaffolded Trimeric HIV-1 Env V1V2 Domain from the Clade AE Strain A244
Descriptor: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase,Envelope glycoprotein gp160, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CH04 Heavy Chain, ...
Authors:Gorman, J, Yang, M, Kwong, P.D.
Deposit date:2015-11-17
Release date:2015-12-16
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (4.191 Å)
Cite:Structures of HIV-1 Env V1V2 with broadly neutralizing antibodies reveal commonalities that enable vaccine design.
Nat. Struct. Mol. Biol., 23, 2016
5ESV
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BU of 5esv by Molmil
Crystal Structure of Broadly Neutralizing Antibody CH03, Isolated from Donor CH0219, in Complex with Scaffolded Trimeric HIV-1 Env V1V2 Domain from the Clade C Superinfecting Strain of Donor CAP256.
Descriptor: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase,Envelope glycoprotein gp160, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Gorman, J, Yang, M, Kwong, P.D.
Deposit date:2015-11-17
Release date:2015-12-16
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.105 Å)
Cite:Structures of HIV-1 Env V1V2 with broadly neutralizing antibodies reveal commonalities that enable vaccine design.
Nat.Struct.Mol.Biol., 23, 2016
4X1H
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BU of 4x1h by Molmil
Opsin/G(alpha) peptide complex stabilized by nonyl-glucoside
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, C-terminal derived peptide of guanine nucleotide-binding protein G(t) subunit alpha-1, PALMITIC ACID, ...
Authors:Blankenship, E, Lodowski, D.T.
Deposit date:2014-11-24
Release date:2015-11-04
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:The High-Resolution Structure of Activated Opsin Reveals a Conserved Solvent Network in the Transmembrane Region Essential for Activation.
Structure, 23, 2015
8PIZ
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BU of 8piz by Molmil
Neisseria meningitidis Type IV pilus SB-DATDH variant bound to the C24 nanobody
Descriptor: 2,4-bisacetamido-2,4,6-trideoxy-beta-D-glucopyranose, C24 nanobody, Pilin, ...
Authors:Fernandez-Martinez, D, Dumenil, G.
Deposit date:2023-06-22
Release date:2024-04-03
Method:ELECTRON MICROSCOPY (2.75 Å)
Cite:Cryo-EM structures of type IV pili complexed with nanobodies reveal immune escape mechanisms.
Nat Commun, 15, 2024
4RQS
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BU of 4rqs by Molmil
Crystal structure of fully glycosylated HIV-1 gp120 core bound to CD4 and 17b Fab
Descriptor: 17b Fab Heavy Chain, 17b Fab Light Chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Kong, L, Wilson, I.A, Kwong, P.D.
Deposit date:2014-11-05
Release date:2014-12-31
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (4.493 Å)
Cite:Crystal structure of a fully glycosylated HIV-1 gp120 core reveals a stabilizing role for the glycan at Asn262.
Proteins, 83, 2015
5LTP
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BU of 5ltp by Molmil
Structure of the Yellow-Green Fluorescent Protein mNeonGreen from Branchiostoma lanceolatum at the acidic pH 4.5
Descriptor: CHLORIDE ION, CITRATE ANION, mNeonGreen
Authors:Clavel, D, Gotthard, G, Royant, A.
Deposit date:2016-09-07
Release date:2016-12-21
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural analysis of the bright monomeric yellow-green fluorescent protein mNeonGreen obtained by directed evolution.
Acta Crystallogr D Struct Biol, 72, 2016
7URS
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BU of 7urs by Molmil
Crystal Structure of SARS-CoV-2 S delta variant receptor-binding domain (RBD) in complex CoV11 Fab crystal form 2
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, COV11 Fab HEAVY CHAIN, ...
Authors:Tolbert, W.D, Pazgier, M.
Deposit date:2022-04-22
Release date:2022-05-04
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The molecular basis of the neutralization breadth of the RBD-specific antibody CoV11.
Front Immunol, 14, 2023
7URQ
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BU of 7urq by Molmil
Crystal Structure of SARS-CoV-2 S delta variant receptor-binding domain (RBD) in complex CoV11 Fab crystal form 1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CITRIC ACID, COV11 Fab HEAVY CHAIN, ...
Authors:Tolbert, W.D, Pazgier, M.
Deposit date:2022-04-22
Release date:2022-05-04
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:The molecular basis of the neutralization breadth of the RBD-specific antibody CoV11.
Front Immunol, 14, 2023
8D86
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BU of 8d86 by Molmil
Isoreticular, interpenetrating co-crystal of Replication Initiator Protein REPE54 and symmetrical expanded duplex (31mer) containing the cognate REPE54 sequence and an additional G-C rich sequence co-crystallized with a guest small molecule, netropsin.
Descriptor: DNA (5'-D(A*CP*CP*CP*GP*GP*AP*CP*CP*TP*GP*TP*GP*AP*CP*AP*AP*AP*TP*TP*GP*CP*CP*CP*TP*CP*AP*GP*AP*CP*GP*G)-3'), DNA (5'-D(A*GP*GP*CP*CP*GP*TP*CP*TP*GP*AP*GP*GP*GP*CP*AP*AP*TP*TP*TP*GP*TP*CP*AP*CP*AP*GP*GP*TP*CP*CP*G)-3'), MAGNESIUM ION, ...
Authors:Orun, A.R, Snow, C.D.
Deposit date:2022-06-07
Release date:2023-06-28
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.12 Å)
Cite:Modular Protein-DNA Cocrystals as Precise, Programmable Assembly Scaffolds.
Acs Nano, 17, 2023
8D8M
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BU of 8d8m by Molmil
Isoreticular, interpenetrating co-crystal of Replication Initiator Protein REPE54 and symmetrical expanded duplex (31mer) containing the cognate REPE54 sequence and an additional G-C rich sequence grown in a calcium chloride crystallization solution.
Descriptor: CALCIUM ION, DNA (5'-D(CP*CP*CP*GP*GP*AP*CP*CP*TP*GP*TP*GP*AP*CP*AP*AP*AP*TP*TP*GP*CP*CP*CP*TP*CP*AP*GP*AP*CP*GP*GP*A)-3'), DNA (5'-D(GP*CP*CP*GP*TP*CP*TP*GP*AP*GP*GP*GP*CP*AP*AP*TP*TP*TP*GP*TP*CP*AP*CP*AP*GP*GP*TP*CP*CP*GP*GP*A)-3'), ...
Authors:Orun, A.R, Snow, C.D.
Deposit date:2022-06-08
Release date:2023-06-28
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Designed crystalline assemblies of protein and DNA enable site-specific installation of a guest protein, DNA, and small molecule.
To Be Published
6R43
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BU of 6r43 by Molmil
Structure of P110 from Mycoplasma Genitalium complexed with 6'-SL
Descriptor: Mgp-operon protein 3, N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-beta-D-glucopyranose, PHOSPHATE ION, ...
Authors:Aparicio, D, Fita, I.
Deposit date:2019-03-21
Release date:2019-04-10
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.52 Å)
Cite:Mycoplasma genitalium adhesin P110 binds sialic-acid human receptors.
Nat Commun, 9, 2018

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数据于2024-09-25公开中

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