PDB: 45459 resultsInfo pagesStatus searchChemie searchBIRD

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4QV8	yCP beta5-C52F mutant Descriptor: CHLORIDE ION, MAGNESIUM ION, Probable proteasome subunit alpha type-7, ... Authors: Huber, E.M, Heinemeyer, W, Groll, M. Deposit date: 2014-07-14 Release date: 2015-02-04 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Bortezomib-Resistant Mutant Proteasomes: Structural and Biochemical Evaluation with Carfilzomib and ONX 0914. Structure, 23, 2015
4QVV	yCP beta5-A49V mutant in complex with bortezomib Descriptor: CHLORIDE ION, MAGNESIUM ION, N-[(1R)-1-(DIHYDROXYBORYL)-3-METHYLBUTYL]-N-(PYRAZIN-2-YLCARBONYL)-L-PHENYLALANINAMIDE, ... Authors: Huber, E.M, Heinemeyer, W, Groll, M. Deposit date: 2014-07-16 Release date: 2015-02-04 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Bortezomib-Resistant Mutant Proteasomes: Structural and Biochemical Evaluation with Carfilzomib and ONX 0914. Structure, 23, 2015
4QWS	yCP beta5-C63F mutant in complex with carfilzomib Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, MAGNESIUM ION, ... Authors: Huber, E.M, Heinemeyer, W, Groll, M. Deposit date: 2014-07-17 Release date: 2015-02-04 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (3 Å) Cite: Bortezomib-Resistant Mutant Proteasomes: Structural and Biochemical Evaluation with Carfilzomib and ONX 0914. Structure, 23, 2015
4QZ6	yCP beta5-A49T-A50V double mutant in complex with the epoxyketone inhibitor ONX 0914 Descriptor: 1,2,4-trideoxy-4-methyl-2-{[N-(morpholin-4-ylacetyl)-L-alanyl-O-methyl-L-tyrosyl]amino}-1-phenyl-D-xylitol, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, ... Authors: Huber, E.M, Heinemeyer, W, Groll, M. Deposit date: 2014-07-27 Release date: 2015-02-04 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Bortezomib-Resistant Mutant Proteasomes: Structural and Biochemical Evaluation with Carfilzomib and ONX 0914. Structure, 23, 2015
4I1D	The crystal structure of an ABC transporter substrate-binding protein from Bradyrhizobium japonicum USDA 110 Descriptor: ABC transporter substrate-binding protein, ACETATE ION, D-MALATE, ... Authors: Fan, Y, Tan, K, Mack, J, Zerbs, S, Collart, F, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) Deposit date: 2012-11-20 Release date: 2012-12-05 Last modified: 2013-09-25 Method: X-RAY DIFFRACTION (2.201 Å) Cite: Structural and functional characterization of solute binding proteins for aromatic compounds derived from lignin: p-Coumaric acid and related aromatic acids. Proteins, 81, 2013
4HZC	Crystal structure of Serine acetyltransferase from Brucella abortus strain S19 Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, CysE, ... Authors: Kumar, S, Samudrala, G. Deposit date: 2012-11-15 Release date: 2014-02-19 Last modified: 2017-11-15 Method: X-RAY DIFFRACTION (1.97 Å) Cite: Crystal structure of serine acetyl transferase from Brucella abortus and its complex with coenzyme A. Biochim.Biophys.Acta, 1844, 2014
4R17	Ligand-induced aziridine-formation at subunit beta5 of the yeast 20S proteasome Descriptor: (2S,3S)-3-methylaziridine-2-carboxylic acid, MAGNESIUM ION, Proteasome subunit alpha type-1, ... Authors: Dubiella, C, Cui, H, Gersch, M, Brouwer, A.J, Sieber, S.A, Krueger, A, Liskamp, R, Groll, M. Deposit date: 2014-08-04 Release date: 2014-10-15 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Selective inhibition of the immunoproteasome by ligand-induced crosslinking of the active site. Angew.Chem.Int.Ed.Engl., 53, 2014
4G7H	Crystal structure of Thermus thermophilus transcription initiation complex Descriptor: 5'-D(*CP*CP*T*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*G)-3', 5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*CP*AP*GP*G)-3', DNA-directed RNA polymerase subunit alpha, ... Authors: Zhang, Y, Ebright, R.H. Deposit date: 2012-07-20 Release date: 2012-10-31 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Structural basis of transcription initiation. Science, 338, 2012
4R57	Crystal structure of spermidine N-acetyltransferase from Vibrio cholerae in complex with acetyl-CoA Descriptor: ACETYL COENZYME *A, DI(HYDROXYETHYL)ETHER, Spermidine n1-acetyltransferase, ... Authors: Filippova, E.V, Minasov, G, Kiryukhina, O, Shuvalova, L, Kuhn, M.L, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) Deposit date: 2014-08-20 Release date: 2015-03-25 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.079 Å) Cite: A Novel Polyamine Allosteric Site of SpeG from Vibrio cholerae Is Revealed by Its Dodecameric Structure. J.Mol.Biol., 427, 2015
4R7M	Structure of the m17 leucyl aminopeptidase from malaria complexed with a hydroxamic acid-based inhibitor Descriptor: 4-amino-N-{(1R)-2-(hydroxyamino)-2-oxo-1-[4-(1H-pyrazol-1-yl)phenyl]ethyl}benzamide, CARBONATE ION, DIMETHYL SULFOXIDE, ... Authors: Drinkwater, N, Mcgowan, S. Deposit date: 2014-08-28 Release date: 2014-10-29 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.85 Å) Cite: Two-Pronged Attack: Dual Inhibition of Plasmodium falciparum M1 and M17 Metalloaminopeptidases by a Novel Series of Hydroxamic Acid-Based Inhibitors. J.Med.Chem., 57, 2014
4G0D	Human collagenase 3 (MMP-13) full form with peptides from pro-domain Descriptor: CALCIUM ION, CHLORIDE ION, Collagenase 3, ... Authors: Stura, E.A, Vera, L, Visse, R, Nagase, H, Dive, V. Deposit date: 2012-07-09 Release date: 2013-08-21 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.54 Å) Cite: Crystal structure of full-length human collagenase 3 (MMP-13) with peptides in the active site defines exosites in the catalytic domain. Faseb J., 27, 2013
4QR1	Crystal structure of Streptococcus pyogenes Cas2 at pH 6.5 Descriptor: CRISPR-associated endoribonuclease Cas2 Authors: Bae, E, Ka, D, Kim, D. Deposit date: 2014-06-30 Release date: 2014-11-26 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.193 Å) Cite: Structural and functional characterization of Streptococcus pyogenes Cas2 protein under different pH conditions Biochem.Biophys.Res.Commun., 451, 2014
4R3O	Human Constitutive 20S Proteasome Descriptor: Proteasome subunit alpha type-1, Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, ... Authors: Sacchettini, J.C, Harshbarger, W.H. Deposit date: 2014-08-16 Release date: 2015-01-28 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Crystal Structure of the Human 20S Proteasome in Complex with Carfilzomib. Structure, 23, 2015
4R88	Crystal structure of 5-methylcytosine deaminase from Klebsiella pneumoniae liganded with 5-fluorocytosine Descriptor: 1,2-ETHANEDIOL, 5-fluorocytosine, ACETIC ACID, ... Authors: Fedorov, A.A, Fedorov, E.V, Hitchcock, D.S, Raushel, F.M, Almo, S.C. Deposit date: 2014-08-29 Release date: 2014-09-17 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.952 Å) Cite: Crystal structure of 5-methylcytosine deaminase from Klebsiella pneumoniae liganded with 5-fluorocytosine To be Published
4QV6	yCP beta5-A49V mutant Descriptor: CHLORIDE ION, MAGNESIUM ION, Probable proteasome subunit alpha type-7, ... Authors: Huber, E.M, Heinemeyer, W, Groll, M. Deposit date: 2014-07-14 Release date: 2015-02-04 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Bortezomib-Resistant Mutant Proteasomes: Structural and Biochemical Evaluation with Carfilzomib and ONX 0914. Structure, 23, 2015
4GMS	Crystal structure of heterosubtypic Fab S139/1 in complex with influenza A H3 hemagglutinin Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab S139/1 heavy chain, ... Authors: Lee, P.S, Ekiert, D.C, Wilson, I.A. Deposit date: 2012-08-16 Release date: 2012-10-03 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.95 Å) Cite: Heterosubtypic antibody recognition of the influenza virus hemagglutinin receptor binding site enhanced by avidity. Proc.Natl.Acad.Sci.USA, 109, 2012
4QW7	yCP beta5-M45T mutant in complex with carfilzomib Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, MAGNESIUM ION, ... Authors: Huber, E.M, Heinemeyer, W, Groll, M. Deposit date: 2014-07-16 Release date: 2015-02-04 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Bortezomib-Resistant Mutant Proteasomes: Structural and Biochemical Evaluation with Carfilzomib and ONX 0914. Structure, 23, 2015
4QXJ	yCP beta5-M45A mutant in complex with the epoxyketone inhibitor ONX 0914 Descriptor: 1,2,4-trideoxy-4-methyl-2-{[N-(morpholin-4-ylacetyl)-L-alanyl-O-methyl-L-tyrosyl]amino}-1-phenyl-D-xylitol, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, ... Authors: Huber, E.M, Heinemeyer, W, Groll, M. Deposit date: 2014-07-21 Release date: 2015-02-04 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Bortezomib-Resistant Mutant Proteasomes: Structural and Biochemical Evaluation with Carfilzomib and ONX 0914. Structure, 23, 2015
4QZW	yCP beta5-C52F mutant in complex with the epoxyketone inhibitor ONX 0914 Descriptor: 1,2,4-trideoxy-4-methyl-2-{[N-(morpholin-4-ylacetyl)-L-alanyl-O-methyl-L-tyrosyl]amino}-1-phenyl-D-xylitol, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, ... Authors: Huber, E.M, Heinemeyer, W, Groll, M. Deposit date: 2014-07-29 Release date: 2015-02-04 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (3 Å) Cite: Bortezomib-Resistant Mutant Proteasomes: Structural and Biochemical Evaluation with Carfilzomib and ONX 0914. Structure, 23, 2015
4R0E	Crystal Structure of the Poliovirus RNA-Dependent RNA Polymerase Low-Fidelity Mutant 3Dpol H273R Descriptor: RNA-directed RNA polymerase Authors: Marcotte, L.L, Gohara, D.W, Filman, D.J, Hogle, J.M. Deposit date: 2014-07-30 Release date: 2014-11-12 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (3 Å) Cite: Structural Dynamics as a Contributor to Error-prone Replication by an RNA-dependent RNA Polymerase. J.Biol.Chem., 289, 2014
4RDR	Structure of the bacterial Zn-transporter ZnuD from Neisseria meningitidis (locked conformation bound to zinc and cadmium ions) Descriptor: (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, 1,2-ETHANEDIOL, CADMIUM ION, ... Authors: Calmettes, C, Moraes, T.F. Deposit date: 2014-09-19 Release date: 2015-08-19 Last modified: 2015-09-16 Method: X-RAY DIFFRACTION (2.472 Å) Cite: The molecular mechanism of Zinc acquisition by the neisserial outer-membrane transporter ZnuD. Nat Commun, 6, 2015
4REU	Revelation of Endogenously bound Fe2+ ions in the Crystal Structure of Ferritin from Escherichia coli Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, FE (III) ION, ... Authors: Thiruselvam, V, Ponnuswamy, M.N, Kumarevel, T.S. Deposit date: 2014-09-24 Release date: 2014-10-22 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Revelation of endogenously bound Fe(2+) ions in the crystal structure of ferritin from Escherichia coli. Biochem.Biophys.Res.Commun., 453, 2014
4R4N	Crystal structure of the anti-hiv-1 antibody 2.2c in complex with hiv-1 93ug037 gp120 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody 2.2c LIGHT CHAIN, Antibody 2.2c heavy CHAIN, ... Authors: Acharya, P, Louder, R, Kwong, P.D. Deposit date: 2014-08-19 Release date: 2014-11-05 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (3.56 Å) Cite: Structural Definition of an Antibody-Dependent Cellular Cytotoxicity Response Implicated in Reduced Risk for HIV-1 Infection. J.Virol., 88, 2014
4QV1	yCP beta5-M45A mutant Descriptor: CHLORIDE ION, MAGNESIUM ION, Probable proteasome subunit alpha type-7, ... Authors: Huber, E.M, Heinemeyer, W, Groll, M. Deposit date: 2014-07-14 Release date: 2015-02-04 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Bortezomib-Resistant Mutant Proteasomes: Structural and Biochemical Evaluation with Carfilzomib and ONX 0914. Structure, 23, 2015
4QW1	yCP beta5-A50V mutant in complex with bortezomib Descriptor: CHLORIDE ION, MAGNESIUM ION, N-[(1R)-1-(DIHYDROXYBORYL)-3-METHYLBUTYL]-N-(PYRAZIN-2-YLCARBONYL)-L-PHENYLALANINAMIDE, ... Authors: Huber, E.M, Heinemeyer, W, Groll, M. Deposit date: 2014-07-16 Release date: 2015-02-04 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Bortezomib-Resistant Mutant Proteasomes: Structural and Biochemical Evaluation with Carfilzomib and ONX 0914. Structure, 23, 2015

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