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7L47
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BU of 7l47 by Molmil
The internal aldimine form of the beta-K167T mutant Tryptophan Synthase from Salmonella at 1.55 Angstrom resolution with cesium ion at the metal coordination site
Descriptor: 1,2-ETHANEDIOL, CESIUM ION, CHLORIDE ION, ...
Authors:Hilario, E, Dunn, M.F, Mueller, L.J.
Deposit date:2020-12-18
Release date:2021-12-29
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:The internal aldimine form of the beta-K167T mutant Tryptophan Synthase from Salmonella at 1.55 Angstrom resolution with cesium ion at the metal coordination site.
To be Published
7KGB
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BU of 7kgb by Molmil
CryoEM structure of A2296-methylated Mycobacterium tuberculosis ribosome bound with SEQ-9
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Cui, Z, Zhang, J.
Deposit date:2020-10-16
Release date:2022-01-19
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Discovery of natural-product-derived sequanamycins as potent oral anti-tuberculosis agents.
Cell, 2023
7KOH
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BU of 7koh by Molmil
Crystal structure of antigen 43 from Escherichia coli EDL933
Descriptor: Antigen 43, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Vo, J.L, Paxman, J.J, Heras, B.
Deposit date:2020-11-09
Release date:2022-03-09
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.98 Å)
Cite:Variation of Antigen 43 self-association modulates bacterial compacting within aggregates and biofilms.
NPJ Biofilms Microbiomes, 8, 2022
7KQN
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BU of 7kqn by Molmil
Ternary complex of TERT (telomerase reverse transcriptase) with RNA template, DNA primer, an incoming dGTP and a downstream hybrid duplex
Descriptor: 1,2-ETHANEDIOL, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ...
Authors:Choi, W.S, Weng, P.J, Yang, W.
Deposit date:2020-11-17
Release date:2022-03-23
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:Flexibility of telomerase in binding the RNA template and DNA telomeric repeat.
Proc.Natl.Acad.Sci.USA, 119, 2022
7KSQ
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BU of 7ksq by Molmil
The Structure of the moss PSI-LHCI reveals the evolution of the LHCI antenna
Descriptor: (3R,3'R,6S)-4,5-DIDEHYDRO-5,6-DIHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, ...
Authors:Riddle, R, Gorski, C, Toporik, H, Dobson, Z, Da, Z, Williams, D, Mazor, Y.
Deposit date:2020-11-23
Release date:2022-03-30
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:The structure of the Physcomitrium patens photosystem I reveals a unique Lhca2 paralogue replacing Lhca4.
Nat.Plants, 8, 2022
7KUX
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BU of 7kux by Molmil
The Structure of the moss PSI-LHCI reveals the evolution of the LHCI antenna
Descriptor: (3R,3'R,6S)-4,5-DIDEHYDRO-5,6-DIHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, ...
Authors:Riddle, R, Gorski, C, Toporik, H, Dobson, Z, Da, Z, Williams, D, Mazor, Y.
Deposit date:2020-11-25
Release date:2022-03-30
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:The structure of the Physcomitrium patens photosystem I reveals a unique Lhca2 paralogue replacing Lhca4.
Nat.Plants, 8, 2022
7LD1
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BU of 7ld1 by Molmil
Structure of SARS-CoV-2 S protein in complex with Receptor Binding Domain antibody DH1047
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DH1047 heavy chain, ...
Authors:Manne, K, Acharya, P.
Deposit date:2021-01-12
Release date:2021-01-27
Last modified:2021-08-18
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:In vitro and in vivo functions of SARS-CoV-2 infection-enhancing and neutralizing antibodies.
Cell, 184, 2021
7LCN
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BU of 7lcn by Molmil
Structure of SARS-CoV-2 S protein in complex with N-terminal domain antibody DH1050.1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DH1050.1 heavy chain, ...
Authors:Manne, K, Acharya, P.
Deposit date:2021-01-11
Release date:2021-01-27
Last modified:2021-08-18
Method:ELECTRON MICROSCOPY (3.35 Å)
Cite:In vitro and in vivo functions of SARS-CoV-2 infection-enhancing and neutralizing antibodies.
Cell, 184, 2021
1WPB
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BU of 1wpb by Molmil
Structure of Escherichia coli yfbU gene product
Descriptor: CHLORIDE ION, GLYCEROL, hypothetical protein yfbU
Authors:Borek, D, Chen, Y, Zheng, M, Skarina, T, Savchenko, A, Edwards, A, Otwinowski, Z, Midwest Center for Structural Genomics (MCSG)
Deposit date:2004-09-01
Release date:2004-12-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of Escherichia coli yfbU gene product
To be Published
7LAB
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BU of 7lab by Molmil
Structure of SARS-CoV-2 S protein in complex with N-terminal domain antibody DH1052
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DH1052 heavy chain, ...
Authors:Manne, K, Acharya, P.
Deposit date:2021-01-06
Release date:2021-03-10
Last modified:2021-08-18
Method:ELECTRON MICROSCOPY (2.97 Å)
Cite:In vitro and in vivo functions of SARS-CoV-2 infection-enhancing and neutralizing antibodies.
Cell, 184, 2021
7LFT
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BU of 7lft by Molmil
Cryo-EM structure of human Apo CNGA1 channel in K+/Ca2+
Descriptor: 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CHOLESTEROL, POTASSIUM ION, ...
Authors:Xue, J, Han, Y, Jiang, Y.
Deposit date:2021-01-18
Release date:2021-03-10
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Structural mechanisms of gating and selectivity of human rod CNGA1 channel.
Neuron, 109, 2021
7LS9
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BU of 7ls9 by Molmil
Cryo-EM structure of neutralizing antibody 1-57 in complex with prefusion SARS-CoV-2 spike glycoprotein
Descriptor: 1-57 Fab heavy chain, 1-57 Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Cerutti, G, Shapiro, L.
Deposit date:2021-02-17
Release date:2021-03-17
Last modified:2021-09-29
Method:ELECTRON MICROSCOPY (3.42 Å)
Cite:Structural basis for accommodation of emerging B.1.351 and B.1.1.7 variants by two potent SARS-CoV-2 neutralizing antibodies.
Structure, 29, 2021
7LNK
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BU of 7lnk by Molmil
Gorilla Bocavirus 1 Capsid
Descriptor: Capsid protein
Authors:Yu, J.C, Mietzsch, M, Agbandje-McKenna, M.
Deposit date:2021-02-07
Release date:2021-03-17
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (2.76 Å)
Cite:Characterization of the GBoV1 Capsid and Its Antibody Interactions.
Viruses, 13, 2021
7LU5
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BU of 7lu5 by Molmil
SAMHD1(113-626) H206R D207N R366H
Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, Deoxynucleoside triphosphate triphosphohydrolase SAMHD1
Authors:Temple, J.T, Bowen, N.E.
Deposit date:2021-02-20
Release date:2021-11-24
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.57 Å)
Cite:Structural and functional characterization explains loss of dNTPase activity of the cancer-specific R366C/H mutant SAMHD1 proteins.
J.Biol.Chem., 297, 2021
7LI9
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BU of 7li9 by Molmil
5-HT bound serotonin transporter reconstituted in lipid nanodisc in KCl
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, DECANE, ...
Authors:Yang, D, Gouaux, E.
Deposit date:2021-01-26
Release date:2021-12-15
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Illumination of serotonin transporter mechanism and role of the allosteric site.
Sci Adv, 7, 2021
7LI8
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BU of 7li8 by Molmil
apo serotonin transporter reconstituted in lipid nanodisc in presence of NaCl in inward open conformation
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DECANE, DODECANE, ...
Authors:Yang, D, Gouaux, E.
Deposit date:2021-01-26
Release date:2021-12-15
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Illumination of serotonin transporter mechanism and role of the allosteric site.
Sci Adv, 7, 2021
7LKY
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BU of 7lky by Molmil
Crystal Structure of PHF1 Tudor domain in complex with a peptidomimetic ligand UNC6641
Descriptor: DIMETHYL SULFOXIDE, Isoform 1 of PHD finger protein 1, Peptidomimetic inhibitor UNC6641, ...
Authors:Liu, J, Kutateladze, T.G.
Deposit date:2021-02-03
Release date:2021-12-15
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Discovery of an H3K36me3-Derived Peptidomimetic Ligand with Enhanced Affinity for Plant Homeodomain Finger Protein 1 (PHF1).
J.Med.Chem., 64, 2021
7LI7
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BU of 7li7 by Molmil
apo serotonin transporter reconstituted in lipid nanodisc in presence of NaCl in occluded conformation
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, DECANE, ...
Authors:Yang, D, Gouaux, E.
Deposit date:2021-01-26
Release date:2021-12-15
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Illumination of serotonin transporter mechanism and role of the allosteric site.
Sci Adv, 7, 2021
7L9E
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BU of 7l9e by Molmil
Crystal structure of apo-alpha glucosidase
Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Karade, S.S, Mariuzza, R.A.
Deposit date:2021-01-03
Release date:2021-12-29
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:N-Substituted Valiolamine Derivatives as Potent Inhibitors of Endoplasmic Reticulum alpha-Glucosidases I and II with Antiviral Activity.
J.Med.Chem., 64, 2021
7LI6
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BU of 7li6 by Molmil
apo SERT reconstituted in lipid nanodisc in KCl
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, DECANE, ...
Authors:Yang, D, Gouaux, E.
Deposit date:2021-01-26
Release date:2021-12-15
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Illumination of serotonin transporter mechanism and role of the allosteric site.
Sci Adv, 7, 2021
7LBD
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BU of 7lbd by Molmil
Dihydrodipicolinate synthase (DHDPS) from C.jejuni, H59K mutant with pyruvate bound in the active site in C2221 space group
Descriptor: 1,2-ETHANEDIOL, 4-hydroxy-tetrahydrodipicolinate synthase, ACETATE ION, ...
Authors:Saran, S, Yazdi, M.M, Sanders, D.A.R.
Deposit date:2021-01-07
Release date:2022-01-12
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Reversing the roles of a crucial hydrogen-bonding pair: a lysine-insensitive mutant of Campylobacter jejuni dihydrodipicolinate synthase, H59K, binds histidine in its allosteric site
To Be Published
1XB1
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BU of 1xb1 by Molmil
The Structure of the BIR domain of IAP-like protein 2
Descriptor: Baculoviral IAP repeat-containing protein 8, Diablo homolog, mitochondrial, ...
Authors:Shin, H, Renatus, M, Eckelman, B.P, Nunes, V.A, Sampaio, C.A.M, Salvesen, G.S.
Deposit date:2004-08-27
Release date:2004-11-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The BIR domain of IAP-like protein 2 is conformationally unstable: implications for caspase inhibition
Biochem.J., 385, 2005
7JQL
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BU of 7jql by Molmil
Crystal structure of the Thermus thermophilus 70S ribosome in complex with Bac7-001, mRNA, and deacylated P-site tRNA at 3.00A resolution
Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Mardirossian, M, Sola, R, Beckert, B, Valencic, E, Collis, D.W.P, Borisek, J, Armas, F, Di Stasi, A, Buchmann, J, Syroegin, E.A, Polikanov, Y.S, Magistrato, A, Hilpert, K, Wilson, D.N, Scocchi, M.
Deposit date:2020-08-11
Release date:2020-08-26
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (3 Å)
Cite:Peptide Inhibitors of Bacterial Protein Synthesis with Broad Spectrum and SbmA-Independent Bactericidal Activity against Clinical Pathogens.
J.Med.Chem., 63, 2020
7JZN
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BU of 7jzn by Molmil
SARS-CoV-2 spike in complex with LCB3 (2RBDs open)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, LCB3, ...
Authors:Park, Y.J, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2020-09-02
Release date:2020-09-23
Last modified:2020-11-04
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:De novo design of picomolar SARS-CoV-2 miniprotein inhibitors.
Science, 370, 2020
7K4B
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BU of 7k4b by Molmil
Cryo-EM structure of human TRPV6 in complex with (4- phenylcyclohexyl)piperazine inhibitor cis-22a
Descriptor: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1-[cis-4-(3-methylphenyl)cyclohexyl]-4-(pyridin-3-yl)piperazine, CALCIUM ION, ...
Authors:Neuberger, A, Nadezhdin, K.D, Singh, A.K, Sobolevsky, A.I.
Deposit date:2020-09-15
Release date:2020-12-09
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Inactivation-mimicking block of the epithelial calcium channel TRPV6.
Sci Adv, 6, 2020

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数据于2024-08-28公开中

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