2X9N
| High resolution structure of TbPTR1 in complex with cyromazine | Descriptor: | (4S,5S)-1,2-DITHIANE-4,5-DIOL, ACETATE ION, DITHIANE DIOL, ... | Authors: | Dawson, A, Tulloch, L.B, Barrack, K.L, Hunter, W.N. | Deposit date: | 2010-03-23 | Release date: | 2010-06-30 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.15 Å) | Cite: | High-Resolution Structures of Trypanosoma Brucei Pteridine Reductase Ligand Complexes Inform on the Placement of New Molecular Entities in the Active Site of a Potential Drug Target Acta Crystallogr.,Sect.D, 66, 2010
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2X9V
| High resolution structure of TbPTR1 with trimetrexate | Descriptor: | ACETATE ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, PTERIDINE REDUCTASE, ... | Authors: | Dawson, A, Tulloch, L.B, Barrack, K.L, Hunter, W.N. | Deposit date: | 2010-03-24 | Release date: | 2010-06-23 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | High-Resolution Structures of Trypanosoma Brucei Pteridine Reductase Ligand Complexes Inform on the Placement of New Molecular Entities in the Active Site of a Potential Drug Target Acta Crystallogr.,Sect.D, 66, 2010
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8RDW
| Cryo-EM structure of P. urativorans 70S ribosome in complex with hibernation factor Balon and EF-Tu(GDP) (structure 3). | Descriptor: | 16S rRNA, 23S rRNA, 5S rRNA, ... | Authors: | Helena-Bueno, K, Rybak, M.Y, Gagnon, M.G, Hill, C.H, Melnikov, S.V. | Deposit date: | 2023-12-08 | Release date: | 2024-02-21 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (2.74 Å) | Cite: | A new family of bacterial ribosome hibernation factors. Nature, 626, 2024
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8RD8
| Cryo-EM structure of P. urativorans 70S ribosome in complex with hibernation factors Balon and RaiA (structure 1). | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S30, ... | Authors: | Helena-Bueno, K, Rybak, M.Y, Gagnon, M.G, Hill, C.H, Melnikov, S.V. | Deposit date: | 2023-12-07 | Release date: | 2024-02-21 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (2.62 Å) | Cite: | A new family of bacterial ribosome hibernation factors. Nature, 626, 2024
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8RDV
| Cryo-EM structure of P. urativorans 70S ribosome in complex with hibernation factor Balon, mRNA and P-site tRNA (structure 2). | Descriptor: | 16S rRNA, 23S rRNA, 5S rRNA, ... | Authors: | Helena-Bueno, K, Rybak, M.Y, Gagnon, M.G, Hill, C.H, Melnikov, S.V. | Deposit date: | 2023-12-08 | Release date: | 2024-02-21 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | A new family of bacterial ribosome hibernation factors. Nature, 626, 2024
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7UYN
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6CMN
| Co-Crystal Structure of HIV-1 TAR Bound to Lab-Evolved RRM TBP6.7 | Descriptor: | TAR-Binding Protein 6.7, Trans-Activation Response RNA Element | Authors: | Belashov, I.A, Wedekind, J.E. | Deposit date: | 2018-03-05 | Release date: | 2018-06-06 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.796 Å) | Cite: | Structure of HIV TAR in complex with a Lab-Evolved RRM provides insight into duplex RNA recognition and synthesis of a constrained peptide that impairs transcription. Nucleic Acids Res., 46, 2018
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4M38
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4M36
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1SJR
| NMR Structure of RRM2 from Human Polypyrimidine Tract Binding Protein Isoform 1 (PTB1) | Descriptor: | Polypyrimidine tract-binding protein 1 | Authors: | Simpson, P.J, Monie, T.P, Szendroi, A, Davydova, N, Tyzack, J.K, Conte, M.R, Read, C.M, Cary, P.D, Svergun, D.I, Konarev, P.V, Petoukhov, M.V, Curry, S, Matthews, S.J. | Deposit date: | 2004-03-04 | Release date: | 2004-09-14 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Structure and RNA Interactions of the N-Terminal RRM Domains of PTB Structure, 12, 2004
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6RX6
| Trypanosoma brucei PTR1 (TbPTR1) in complex with inhibitor 4 (NMT-C0026) | Descriptor: | ACETATE ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Pteridine reductase, ... | Authors: | Landi, G, Pozzi, C, Mangani, S. | Deposit date: | 2019-06-07 | Release date: | 2020-07-15 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.11 Å) | Cite: | Multitarget, Selective Compound Design Yields Potent Inhibitors of a Kinetoplastid Pteridine Reductase 1. J.Med.Chem., 65, 2022
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4M37
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2QRY
| Periplasmic thiamin binding protein | Descriptor: | THIAMIN PHOSPHATE, Thiamine-binding periplasmic protein | Authors: | Ealick, S.E, Soriano, E.V. | Deposit date: | 2007-07-30 | Release date: | 2008-02-05 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Structural Similarities between Thiamin-Binding Protein and Thiaminase-I Suggest a Common Ancestor Biochemistry, 47, 2008
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1SJQ
| NMR Structure of RRM1 from Human Polypyrimidine Tract Binding Protein Isoform 1 (PTB1) | Descriptor: | Polypyrimidine tract-binding protein 1 | Authors: | Simpson, P.J, Monie, T.P, Szendroi, A, Davydova, N, Tyzack, J.K, Conte, M.R, Read, C.M, Cary, P.D, Svergun, D.I, Konarev, P.V, Petoukhov, M.V, Curry, S, Matthews, S.J. | Deposit date: | 2004-03-04 | Release date: | 2004-09-14 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Structure and RNA Interactions of the N-Terminal RRM Domains of PTB Structure, 12, 2004
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8BGF
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2L15
| Solution Structure of Cold Shock Protein CspA Using Combined NMR and CS-Rosetta method | Descriptor: | Cold shock protein CspA | Authors: | Tang, Y, Schneider, W.M, Shen, Y, Raman, S, Inouye, M, Baker, D, Roth, M.J, Montelione, G.T. | Deposit date: | 2010-07-22 | Release date: | 2010-09-15 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Fully automated high-quality NMR structure determination of small (2)H-enriched proteins. J Struct Funct Genomics, 11, 2010
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2YMD
| Crystal structure of a mutant binding protein (5HTBP-AChBP) in complex with serotonin (5-hydroxytryptamine) | Descriptor: | GLYCEROL, PHOSPHATE ION, SEROTONIN, ... | Authors: | Kesters, D, Thompson, A.J, Brams, M, Elk, R.v, Spurny, R, Geitmann, M, Villalgordo, J.M, Guskov, A, Danielson, U.H, Lummis, S.C.R, Smit, A.B, Ulens, C. | Deposit date: | 2012-10-09 | Release date: | 2012-12-12 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.96 Å) | Cite: | Structural Basis of Ligand Recognition in 5-Ht(3) Receptors. Embo Rep., 14, 2013
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2C7V
| Structure of Trypanosoma brucei pteridine reductase (PTR1) in ternary complex with cofactor and the antifolate methotrexate | Descriptor: | ACETATE ION, METHOTREXATE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | Authors: | Dawson, A, Gibellini, F, Sienkiewicz, N, Fyfe, P.K, McLuskey, K, Fairlamb, A.H, Hunter, W.N. | Deposit date: | 2005-11-29 | Release date: | 2006-09-19 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure and Reactivity of Trypanosoma Brucei Pteridine Reductase: Inhibition by the Archetypal Antifolate Methotrexate Mol.Microbiol., 61, 2006
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2N3O
| Structure of PTB RRM1(41-163) bound to an RNA stemloop containing a structured loop derived from viral internal ribosomal entry site RNA | Descriptor: | Polypyrimidine tract-binding protein 1, RNA (5'-R(*GP*GP*GP*AP*CP*CP*UP*GP*GP*UP*CP*UP*UP*UP*CP*CP*AP*GP*GP*UP*CP*CP*C)-3') | Authors: | Maris, C, Jayne, S.F, Damberger, F.F, Ravindranathan, S, Allain, F.H.-T. | Deposit date: | 2015-06-08 | Release date: | 2016-08-10 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | C-terminal helix folding upon pyrimidine-rich hairpin binding to PTB RRM1. Implications for PTB function in Encephalomyocarditis virus IRES activity. To be Published
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1BRQ
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1BRP
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1AQB
| RETINOL-BINDING PROTEIN (RBP) FROM PIG PLASMA | Descriptor: | CADMIUM ION, RETINOL, RETINOL-BINDING PROTEIN | Authors: | Zanotti, G, Panzalorto, M, Marcato, A, Malpeli, G, Folli, C, Berni, R. | Deposit date: | 1997-07-28 | Release date: | 1998-01-28 | Last modified: | 2023-08-02 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Structure of pig plasma retinol-binding protein at 1.65 A resolution. Acta Crystallogr.,Sect.D, 54, 1998
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1JYJ
| Crystal Structure of a Double Variant (W67L/W91H) of Recombinant Human Serum Retinol-binding Protein at 2.0 A Resolution | Descriptor: | GLYCEROL, PLASMA RETINOL-BINDING PROTEIN | Authors: | Greene, L.H, Chrysina, E.D, Irons, L.I, Papageorgiou, A.C, Acharya, K.R, Brew, K. | Deposit date: | 2001-09-12 | Release date: | 2003-07-01 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Role of Conserved Residues in Structure and Stability: Tryptophans of Human Serum Retinol-Binding Protein, a Model for the Lipocalin Superfamily Protein Sci., 10, 2001
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1KT3
| Crystal structure of bovine holo-RBP at pH 2.0 | Descriptor: | Plasma retinol-binding protein, RETINOL | Authors: | Calderone, V, Berni, R, Zanotti, G. | Deposit date: | 2002-01-15 | Release date: | 2003-06-03 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | High-resolution Structures of
Retinol-binding Protein in
Complex with Retinol: pH-induced Protein Structural
Changes in the Crystal State J.Mol.Biol., 329, 2003
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1KT7
| Crystal structure of bovine holo-RBP at pH 7.0 | Descriptor: | Plasma retinol-binding protein, RETINOL | Authors: | Calderone, V, Berni, R, Zanotti, G. | Deposit date: | 2002-01-15 | Release date: | 2003-06-03 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.274 Å) | Cite: | High-resolution Structures of Retinol-binding Protein in
Complex with Retinol: pH-induced Protein Structural
Changes in the Crystal State J.Mol.Biol., 329, 2003
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