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7AJJ
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BU of 7ajj by Molmil
bovine ATP synthase dimer state3:state3
Descriptor: 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, ATP synthase F(0) complex subunit B1, mitochondrial, ...
Authors:Spikes, T.E, Montgomery, M.G, Walker, J.E.
Deposit date:2020-09-29
Release date:2021-02-03
Last modified:2021-02-24
Method:ELECTRON MICROSCOPY (13.1 Å)
Cite:Interface mobility between monomers in dimeric bovine ATP synthase participates in the ultrastructure of inner mitochondrial membranes.
Proc.Natl.Acad.Sci.USA, 118, 2021
1Y1N
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BU of 1y1n by Molmil
Identification of SH3 motif in M. Tuberculosis methionine aminopeptidase suggests a mode of interaction with the ribosome
Descriptor: Methionine aminopeptidase 1B, POTASSIUM ION
Authors:Addlagatta, A, Quillin, M.L, Omotoso, O, Liu, J.O, Matthews, B.W.
Deposit date:2004-11-18
Release date:2005-05-24
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.51 Å)
Cite:Identification of an SH3-Binding Motif in a New Class of Methionine Aminopeptidases from Mycobacterium tuberculosis Suggests a Mode of Interaction with the Ribosome
Biochemistry, 44, 2005
7AGF
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BU of 7agf by Molmil
HAd7 knob in complex with 3 EC2-EC3 modules of DSG-2
Descriptor: Desmoglein-2, Fiber
Authors:Effantin, G, Vassal-Stermann, E, Fender, P.
Deposit date:2020-09-22
Release date:2020-10-14
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Binding Mechanism Elucidation of the Acute Respiratory Disease Causing Agent Adenovirus of Serotype 7 to Desmoglein-2.
Viruses, 12, 2020
3FM9
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BU of 3fm9 by Molmil
Analysis of the Structural Determinants Underlying Discrimination between Substrate and Solvent in beta-Phosphoglucomutase Catalysis
Descriptor: Beta-phosphoglucomutase, MAGNESIUM ION
Authors:Finci, L, Lahiri, S, Peisach, E, Allen, K.N.
Deposit date:2008-12-19
Release date:2009-06-09
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Analysis of the structural determinants underlying discrimination between substrate and solvent in beta-phosphoglucomutase catalysis.
Biochemistry, 48, 2009
7ASD
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BU of 7asd by Molmil
Structure of native royal jelly filaments
Descriptor: (3beta,14beta,17alpha)-ergosta-5,24(28)-dien-3-ol, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Mattei, S, Ban, A, Picenoni, A, Leibundgut, M, Glockshuber, R, Boehringer, D.
Deposit date:2020-10-27
Release date:2020-12-30
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structure of native glycolipoprotein filaments in honeybee royal jelly.
Nat Commun, 11, 2020
4RWJ
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BU of 4rwj by Molmil
Crystal Structure of FGFR1 (C488A, C584S) in complex with AZD4547 (N-{3-[2-(3,5-DIMETHOXYPHENYL)ETHYL]-1H-PYRAZOL-5-YL}-4-[(3R,5S)-3,5-DIMETHYLPIPERAZIN-1-YL]BENZAMIDE)
Descriptor: Fibroblast growth factor receptor 1, N-{3-[2-(3,5-dimethoxyphenyl)ethyl]-1H-pyrazol-5-yl}-4-[(3R,5S)-3,5-dimethylpiperazin-1-yl]benzamide
Authors:Sohl, C.D, Anderson, K.S.
Deposit date:2014-12-04
Release date:2015-04-22
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.489 Å)
Cite:Illuminating the Molecular Mechanisms of Tyrosine Kinase Inhibitor Resistance for the FGFR1 Gatekeeper Mutation: The Achilles' Heel of Targeted Therapy.
Acs Chem.Biol., 10, 2015
1Y8X
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BU of 1y8x by Molmil
Structural basis for recruitment of Ubc12 by an E2-binding domain in NEDD8's E1
Descriptor: Ubiquitin-activating enzyme E1C, Ubiquitin-conjugating enzyme E2 M
Authors:Huang, D.T, Paydar, A, Zhuang, M, Waddell, M.B, Holton, J.M, Schulman, B.A.
Deposit date:2004-12-13
Release date:2005-02-08
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis for recruitment of Ubc12 by an E2 binding domain in NEDD8's E1.
Mol.Cell, 17, 2005
7AJD
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BU of 7ajd by Molmil
bovine ATP synthase dimer state1:state3
Descriptor: 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, ATP synthase F(0) complex subunit B1, mitochondrial, ...
Authors:Spikes, T.E, Montgomery, M.G, Walker, J.E.
Deposit date:2020-09-29
Release date:2021-02-03
Last modified:2021-02-24
Method:ELECTRON MICROSCOPY (9 Å)
Cite:Interface mobility between monomers in dimeric bovine ATP synthase participates in the ultrastructure of inner mitochondrial membranes.
Proc.Natl.Acad.Sci.USA, 118, 2021
7AJH
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BU of 7ajh by Molmil
bovine ATP synthase dimer state3:state1
Descriptor: 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, ATP synthase F(0) complex subunit B1, mitochondrial, ...
Authors:Spikes, T.E, Montgomery, M.G, Walker, J.E.
Deposit date:2020-09-29
Release date:2021-02-03
Last modified:2021-02-24
Method:ELECTRON MICROSCOPY (9.7 Å)
Cite:Interface mobility between monomers in dimeric bovine ATP synthase participates in the ultrastructure of inner mitochondrial membranes.
Proc.Natl.Acad.Sci.USA, 118, 2021
2FO1
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BU of 2fo1 by Molmil
Crystal Structure of the CSL-Notch-Mastermind ternary complex bound to DNA
Descriptor: 5'-D(*AP*AP*TP*CP*TP*TP*TP*CP*CP*CP*AP*CP*AP*GP*T)-3', 5'-D(*TP*TP*AP*CP*TP*GP*TP*GP*GP*GP*AP*AP*AP*GP*A)-3', Lin-12 and glp-1 phenotype protein 1, ...
Authors:Wilson, J.J, Kovall, R.A.
Deposit date:2006-01-12
Release date:2006-03-21
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (3.12 Å)
Cite:Crystal structure of the CSL-Notch-Mastermind ternary complex bound to DNA.
Cell(Cambridge,Mass.), 124, 2006
7AJC
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BU of 7ajc by Molmil
bovine ATP synthase dimer state1:state2
Descriptor: 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, ATP synthase F(0) complex subunit B1, mitochondrial, ...
Authors:Spikes, T.E, Montgomery, M.G, Walker, J.E.
Deposit date:2020-09-29
Release date:2021-02-03
Last modified:2021-02-24
Method:ELECTRON MICROSCOPY (11.9 Å)
Cite:Interface mobility between monomers in dimeric bovine ATP synthase participates in the ultrastructure of inner mitochondrial membranes.
Proc.Natl.Acad.Sci.USA, 118, 2021
7EJ9
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BU of 7ej9 by Molmil
Alternative crystal structure of mouse Cryptochrome 2 in complex with TH301 compound
Descriptor: 1-(4-chlorophenyl)-N-[2-(4-methoxyphenyl)-5,5-bis(oxidanylidene)-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]cyclopentane-1-carboxamide, Cryptochrome-2
Authors:Miller, S.A, Hirota, T.
Deposit date:2021-04-01
Release date:2021-06-23
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural differences in the FAD-binding pockets and lid loops of mammalian CRY1 and CRY2 for isoform-selective regulation.
Proc.Natl.Acad.Sci.USA, 118, 2021
4TLZ
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BU of 4tlz by Molmil
Kutzneria sp. 744 ornithine N-hydroxylase, KtzI-FADox-NADP+-L-orn
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, KtzI, L-ornithine, ...
Authors:Setser, J.W, Drennan, C.L.
Deposit date:2014-05-30
Release date:2014-09-17
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.411 Å)
Cite:Crystallographic Evidence of Drastic Conformational Changes in the Active Site of a Flavin-Dependent N-Hydroxylase.
Biochemistry, 53, 2014
6BAK
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BU of 6bak by Molmil
The structure of the Stigmatella aurantiaca phytochrome chromophore binding domain T289H mutant
Descriptor: 3-[5-[(Z)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-2-[[5-[(Z)-(3-ethenyl-4-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-3-(3-hydroxy-3-oxopropyl)-4-methyl-1H-pyrrol-2-yl]methyl]-4-methyl-1H-pyrrol-3-yl]propanoic acid, Photoreceptor-histidine kinase BphP
Authors:Schmidt, M, Stojkovic, E.
Deposit date:2017-10-13
Release date:2018-09-19
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Structural basis for light control of cell development revealed by crystal structures of a myxobacterial phytochrome.
IUCrJ, 5, 2018
4RQ5
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BU of 4rq5 by Molmil
Human DNA Polymerase Beta With Gapped DNA Containing an 8-oxo-7,8-dihydro-Guanine (8-oxoG)and dATP soaked with MgCl2 for 60 s
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, ACETATE ION, CHLORIDE ION, ...
Authors:Vyas, R, Suo, Z.
Deposit date:2014-10-31
Release date:2015-04-15
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.32 Å)
Cite:Viewing Human DNA Polymerase beta Faithfully and Unfaithfully Bypass an Oxidative Lesion by Time-Dependent Crystallography.
J.Am.Chem.Soc., 137, 2015
3U88
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BU of 3u88 by Molmil
Crystal structure of human menin in complex with MLL1 and LEDGF
Descriptor: (4beta,8alpha,9R)-6'-methoxy-10,11-dihydrocinchonan-9-ol, CHOLIC ACID, GLYOXYLIC ACID, ...
Authors:Huang, J, Wan, B, Lei, M.
Deposit date:2011-10-16
Release date:2012-02-15
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (3 Å)
Cite:The same pocket in menin binds both MLL and JUND but has opposite effects on transcription.
Nature, 482, 2012
1Y5W
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BU of 1y5w by Molmil
tRNA-guanine Transglycosylase (TGT) in complex with 6-Amino-4-[2-(4-methylphenyl)ethyl]-1,7-dihydro-8H-imidazo[4,5-g]quinazolin-8-one
Descriptor: 6-AMINO-4-[2-(4-METHYLPHENYL)ETHYL]-1,7-DIHYDRO-8H-IMIDAZO[4,5-G]QUINAZOLIN-8-ONE, GLYCEROL, Queuine tRNA-ribosyltransferase, ...
Authors:Stengl, B, Meyer, E.A, Heine, A, Brenk, R, Diederich, F, Klebe, G.
Deposit date:2004-12-03
Release date:2005-12-13
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:Crystal structures of tRNA-guanine transglycosylase (TGT) in complex with novel and potent inhibitors unravel pronounced induced-fit adaptations and suggest dimer formation upon substrate binding
J.Mol.Biol., 370, 2007
1KX8
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BU of 1kx8 by Molmil
Antennal Chemosensory Protein A6 from Mamestra brassicae, tetragonal form
Descriptor: CHEMOSENSORY PROTEIN A6
Authors:Lartigue, A, Campanacci, V, Roussel, A, Larsson, A.M, Jones, T.A, Tegoni, M, Cambillau, C.
Deposit date:2002-01-31
Release date:2002-12-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:X-Ray Structure and Ligand Binding Study of a Chemosensory Protein
J.Biol.Chem., 277, 2002
4TQ8
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BU of 4tq8 by Molmil
Dual binding mode for 3-(9H-fluoren-9-ylideneaminooxy)propanoic acid binding to Human transthyretin (TTR)
Descriptor: 1,2-ETHANEDIOL, 3-[(9H-fluoren-9-ylideneamino)oxy]propanoic acid, Transthyretin
Authors:Ciccone, L, Orlandini, E, Nencetti, S, Rossello, A, Stura, E.A.
Deposit date:2014-06-10
Release date:2015-06-24
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.52 Å)
Cite:X-ray crystal structure and activity of fluorenyl-based compounds as transthyretin fibrillogenesis inhibitors.
J Enzyme Inhib Med Chem, 2015
4RSU
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BU of 4rsu by Molmil
Crystal structure of the light and hvem complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, GLYCEROL, ...
Authors:Liu, W, Ramagoal, U.A, Himmel, D, Bonanno, J.B, Nathenson, S.G, Almo, S.C, Atoms-to-Animals: The Immune Function Network (IFN), New York Structural Genomics Research Consortium (NYSGRC)
Deposit date:2014-11-11
Release date:2015-02-04
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:HVEM structures and mutants reveal distinct functions of binding to LIGHT and BTLA/CD160.
J.Exp.Med., 218, 2021
7AJB
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BU of 7ajb by Molmil
bovine ATP synthase dimer state1:state1
Descriptor: 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, ATP synthase F(0) complex subunit B1, mitochondrial, ...
Authors:Spikes, T.E, Montgomery, M.G, Walker, J.E.
Deposit date:2020-09-29
Release date:2021-02-03
Last modified:2021-02-24
Method:ELECTRON MICROSCOPY (9.2 Å)
Cite:Interface mobility between monomers in dimeric bovine ATP synthase participates in the ultrastructure of inner mitochondrial membranes.
Proc.Natl.Acad.Sci.USA, 118, 2021
4RUG
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BU of 4rug by Molmil
Cyrstal structure of SLIT-ROBO Rho GTPase-activating protein 2 fragment
Descriptor: SLIT-ROBO Rho GTPase-activating protein 2
Authors:Opatowsky, Y, Guez-Hadad, J.
Deposit date:2014-11-19
Release date:2015-11-04
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:The Neuronal Migration Factor srGAP2 Achieves Specificity in Ligand Binding through a Two-Component Molecular Mechanism.
Structure, 23, 2015
3TLJ
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BU of 3tlj by Molmil
Crystal structure of Trm14 from Pyrococcus furiosus in complex with S-adenosyl-L-homocysteine
Descriptor: ACETATE ION, S-ADENOSYL-L-HOMOCYSTEINE, tRNA (guanine N2-)-methyltransferase Trm14
Authors:Fislage, M, Roovers, M, Tuszynska, I, Bujnicki, J.M, Droogmans, L, Versees, W.
Deposit date:2011-08-30
Release date:2012-03-14
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structures of the tRNA:m2G6 methyltransferase Trm14/TrmN from two domains of life.
Nucleic Acids Res., 40, 2012
4S1L
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BU of 4s1l by Molmil
Structure of Uranotaenia sapphirina cypovirus (CPV17) polyhedrin at 298 K
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, polyhedrin
Authors:Ginn, H.M, Messerschmidt, M, Ji, X, Zhang, H, Axford, D, Gildea, R.J, Winter, G, Brewster, A.S, Hattne, J, Wagner, A, Grimes, J.M, Evans, G, Sauter, N.K, Sutton, G, Stuart, D.I.
Deposit date:2015-01-14
Release date:2015-03-25
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.752 Å)
Cite:Structure of CPV17 polyhedrin determined by the improved analysis of serial femtosecond crystallographic data.
Nat Commun, 6, 2015
3TLS
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BU of 3tls by Molmil
The GLIC pentameric Ligand-Gated Ion Channel E19'P mutant in a locally-closed conformation (LC2 subtype)
Descriptor: CHLORIDE ION, DODECYL-BETA-D-MALTOSIDE, Glr4197 protein
Authors:Sauguet, L, Nury, H, Corringer, P.J, Delarue, M.
Deposit date:2011-08-30
Release date:2012-05-16
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:A locally closed conformation of a bacterial pentameric proton-gated ion channel.
Nat.Struct.Mol.Biol., 19, 2012

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