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4N7Q
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Crystal structure of eukaryotic THIC from A. thaliana
Descriptor: COBALT (II) ION, HEXANE-1,6-DIOL, Phosphomethylpyrimidine synthase, ...
Authors:Coquille, S.C, Roux, C, Mehta, A, Begley, T.P, Fitzpatrick, T.B, Thore, S.
Deposit date:2013-10-16
Release date:2013-11-13
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:High-resolution crystal structure of the eukaryotic HMP-P synthase (THIC) from Arabidopsis thaliana.
J.Struct.Biol., 184, 2013
4ZKY
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BU of 4zky by Molmil
Structure of F420 binding protein, MSMEG_6526, from Mycobacterium smegmatis
Descriptor: CHLORIDE ION, IODIDE ION, Pyridoxamine 5-phosphate oxidase, ...
Authors:Lee, B.M, Carr, P.D, Ahmed, F.H, Jackson, C.J.
Deposit date:2015-05-01
Release date:2015-10-28
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Sequence-Structure-Function Classification of a Catalytically Diverse Oxidoreductase Superfamily in Mycobacteria.
J.Mol.Biol., 427, 2015
3ZZL
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BU of 3zzl by Molmil
Bacillus halodurans trp RNA-binding attenuation protein (TRAP): a 12- subunit assembly
Descriptor: TRANSCRIPTION ATTENUATION PROTEIN MTRB, TRYPTOPHAN
Authors:Chen, C, Smits, C, Dodson, G.G, Shevtsov, M.B, Merlino, N, Gollnick, P, Antson, A.A.
Deposit date:2011-09-01
Release date:2011-10-12
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:How to Change the Oligomeric State of a Circular Protein Assembly: Switch from 11-Subunit to 12-Subunit Trap Suggests a General Mechanism
Plos One, 6, 2011
4ZG7
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BU of 4zg7 by Molmil
Structural basis for inhibition of human autotaxin by four novel compounds
Descriptor: (2R)-2-hydroxy-3-(phosphonooxy)propyl tetradecanoate, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3-({6-chloro-7-fluoro-2-methyl-1-[2-oxo-2-(spiro[cyclopropane-1,3'-indol]-1'(2'H)-yl)ethyl]-1H-indol-3-yl}sulfanyl)-2-fluorobenzoic acid, ...
Authors:Stein, A.J, Bain, G, Hutchinson, J.H, Evans, J.F.
Deposit date:2015-04-22
Release date:2015-10-14
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural Basis for Inhibition of Human Autotaxin by Four Potent Compounds with Distinct Modes of Binding.
Mol.Pharmacol., 88, 2015
4ZOC
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Crystal Structure of mutant (D270A) beta-glucosidase from Listeria innocua in complex with sophorotriose
Descriptor: GLYCEROL, Lin1840 protein, MAGNESIUM ION, ...
Authors:Nakajima, M, Yoshida, R, Miyanaga, A, Abe, K, Takahashi, Y, Sugimoto, N, Toyoizumi, H, Nakai, H, Kitaoka, M, Taguchi, H.
Deposit date:2015-05-06
Release date:2016-05-18
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Functional and Structural Analysis of a beta-Glucosidase Involved in beta-1,2-Glucan Metabolism in Listeria innocua
Plos One, 11, 2016
4ZGG
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BU of 4zgg by Molmil
Crystal structure of a DJ-1 (PARK7) from Homo sapiens at 1.23 A resolution
Descriptor: 1,2-ETHANEDIOL, Protein deglycase DJ-1
Authors:Joint Center for Structural Genomics (JCSG), Partnership for Nuclear Receptor Signaling Code Biology (NHRS), Partnership for T-Cell Biology (TCELL)
Deposit date:2015-04-22
Release date:2015-05-20
Last modified:2023-02-01
Method:X-RAY DIFFRACTION (1.23 Å)
Cite:Crystal structure of a DJ-1 (PARK7) from Homo sapiens at 1.23 A resolution
To be published
4N1E
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BU of 4n1e by Molmil
Structural evidence for antigen receptor evolution
Descriptor: Lysozyme C, immunoglobulin variable light chain domain
Authors:Langley, D.B, Rouet, R, Stock, D, Christ, D.
Deposit date:2013-10-04
Release date:2014-10-29
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:Structural reconstruction of protein ancestry.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
3ZKJ
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BU of 3zkj by Molmil
Crystal Structure of Ankyrin Repeat and Socs Box-Containing Protein 9 (Asb9) in Complex with Elonginb and Elonginc
Descriptor: 1,2-ETHANEDIOL, ANKYRIN REPEAT AND SOCS BOX PROTEIN 9, CHLORIDE ION, ...
Authors:Muniz, J.R.C, Guo, K, Zhang, Y, Ayinampudi, V, Savitsky, P, Keates, T, Filippakopoulos, P, Vollmar, M, Yue, W.W, Krojer, T, Ugochukwu, E, von Delft, F, Knapp, S, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Bullock, A.N.
Deposit date:2013-01-23
Release date:2013-01-30
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.58 Å)
Cite:Molecular Architecture of the Ankyrin Socs Box Family of Cul5-Dependent E3 Ubiquitin Ligases
J.Mol.Biol., 425, 2013
4N42
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Crystal structure of allergen protein scam1 from Scadoxus multiflorus
Descriptor: PHOSPHATE ION, Xylanase and alpha-amylase inhibitor protein isoform III
Authors:Singh, A, Kumar, S, Sinha, M, Kaur, P, Sharma, S, Singh, T.P.
Deposit date:2013-10-08
Release date:2013-10-30
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of allergen protein scam1 from Scadoxus multiflorus
To be published
4OCM
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BU of 4ocm by Molmil
Crystal Structure of the Rpn8-Rpn11 MPN domain heterodimer, crystal form Ib
Descriptor: 26S proteasome regulatory subunit RPN11, 26S proteasome regulatory subunit RPN8, Nb1, ...
Authors:Pathare, G.R, Bracher, A.
Deposit date:2014-01-09
Release date:2014-01-29
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Crystal structure of the proteasomal deubiquitylation module Rpn8-Rpn11.
Proc.Natl.Acad.Sci.USA, 111, 2014
4ZOD
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BU of 4zod by Molmil
Crystal Structure of beta-glucosidase from Listeria innocua in complex with glucose
Descriptor: DI(HYDROXYETHYL)ETHER, GLYCEROL, Lin1840 protein, ...
Authors:Nakajima, M, Yoshida, R, Miyanaga, A, Abe, K, Takahashi, Y, Sugimoto, N, Toyoizumi, H, Nakai, H, Kitaoka, M, Taguchi, H.
Deposit date:2015-05-06
Release date:2016-05-18
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Functional and Structural Analysis of a beta-Glucosidase Involved in beta-1,2-Glucan Metabolism in Listeria innocua
Plos One, 11, 2016
4OWC
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BU of 4owc by Molmil
PtI6 binding to HEWL
Descriptor: CHLORIDE ION, IODIDE ION, Lysozyme C, ...
Authors:Tanley, S.W.M, Starkey, V.L, Lamplough, L, Kaenket, S, Helliwell, J.R.
Deposit date:2014-01-31
Release date:2014-09-24
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:The binding of platinum hexahalides (Cl, Br and I) to hen egg-white lysozyme and the chemical transformation of the PtI6 octahedral complex to a PtI3 moiety bound to His15.
Acta Crystallogr.,Sect.F, 70, 2014
3ZZZ
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BU of 3zzz by Molmil
Crystal structure of a Raver1 PRI4 peptide in complex with polypyrimidine tract binding protein RRM2
Descriptor: IODIDE ION, POLYPYRIMIDINE TRACT-BINDING PROTEIN 1, RIBONUCLEOPROTEIN PTB-BINDING 1
Authors:Joshi, A, Kotik-Kogan, O, Curry, S.
Deposit date:2011-09-06
Release date:2011-12-28
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Crystallographic Analysis of Polypyrimidine Tract-Binding Protein-Raver1 Interactions Involved in Regulation of Alternative Splicing.
Structure, 19, 2011
4AU5
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BU of 4au5 by Molmil
Structure of the NhaA dimer, crystallised at low pH
Descriptor: DODECYL-ALPHA-D-MALTOSIDE, NA(+)/H(+) ANTIPORTER NHAA, SULFATE ION
Authors:Drew, D, Lee, C, Iwata, S, Cameron, A.D.
Deposit date:2012-05-14
Release date:2013-07-10
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.696 Å)
Cite:Crystal structure of the sodium-proton antiporter NhaA dimer and new mechanistic insights.
J. Gen. Physiol., 144, 2014
4AXK
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BU of 4axk by Molmil
CRYSTAL STRUCTURE OF subHisA from the thermophile Corynebacterium efficiens
Descriptor: 1-(5-PHOSPHORIBOSYL)-5-((5'-PHOSPHORIBOSYLAMINO) METHYLIDENEAMINO)IMIDAZOLE-4-CARBOXAMIDE ISOMERASE, GLYCEROL
Authors:Noda-Garcia, L, Camacho-Zarco, A.R, Medina-Ruiz, S, Verduzco-Castro, E.A, Gaytan, P, Carrillo-Tripp, M, Fulop, V, Barona-Gomez, F.
Deposit date:2012-06-13
Release date:2013-06-26
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Evolution of Substrate Specificity in a Recipient'S Enzyme Following Horizontal Gene Transfer.
Mol.Biol.Evol., 30, 2013
4O6R
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BU of 4o6r by Molmil
Crystal Structure of a Putative Aldehyde Dehydrogenase from Burkholderia cenocepacia
Descriptor: 1,2-ETHANEDIOL, ADENOSINE MONOPHOSPHATE, Aldehyde Dehydrogenase, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2013-12-23
Release date:2014-01-22
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal Structure of a Putative Aldehyde Dehydrogenase from Burkholderia cenocepacia
TO BE PUBLISHED
4ZU3
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BU of 4zu3 by Molmil
Halohydrin hydrogen-halide-lyases, HheB
Descriptor: 3-hydroxypentanedinitrile, Halohydrin epoxidase B, MAGNESIUM ION, ...
Authors:Watanabe, F, Yu, F, Ohtaki, A, Yamanaka, Y, Noguchi, K, Yohda, M, Odaka, M.
Deposit date:2015-05-15
Release date:2015-11-04
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structures of halohydrin hydrogen-halide-lyases from Corynebacterium sp. N-1074
Proteins, 83, 2015
4ZSU
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BU of 4zsu by Molmil
Crystal structure of Brevundimonas diminuta phosphotriesterase mutant L7eP-3aG
Descriptor: COBALT (II) ION, Parathion hydrolase
Authors:Mabanglo, M.F, Raushel, F.M.
Deposit date:2015-05-14
Release date:2015-09-02
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.011 Å)
Cite:Variants of Phosphotriesterase for the Enhanced Detoxification of the Chemical Warfare Agent VR.
Biochemistry, 54, 2015
4ZX5
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BU of 4zx5 by Molmil
X-ray crystal structure of PfA-M1 in complex with hydroxamic acid-based inhibitor 10q
Descriptor: DIMETHYL SULFOXIDE, GLYCEROL, M1 family aminopeptidase, ...
Authors:Drinkwater, N, McGowan, S.
Deposit date:2015-05-20
Release date:2016-03-30
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Potent dual inhibitors of Plasmodium falciparum M1 and M17 aminopeptidases through optimization of S1 pocket interactions.
Eur.J.Med.Chem., 110, 2016
4B3P
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BU of 4b3p by Molmil
Structures of HIV-1 RT and RNA-DNA Complex Reveal a Unique RT Conformation and Substrate Interface
Descriptor: DNA, P51 RT, REVERSE TRANSCRIPTASE/RIBONUCLEASE H, ...
Authors:Lapkouski, M, Tian, L, Miller, J.T, Le Grice, S.F.J, Yang, W.
Deposit date:2012-07-25
Release date:2013-01-16
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (4.839 Å)
Cite:Complexes of HIV-1 RT, Nnrti and RNA/DNA Hybrid Reveal a Structure Compatible with RNA Degradation
Nat.Struct.Mol.Biol., 20, 2013
4ZW5
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BU of 4zw5 by Molmil
X-ray crystal structure of PfA-M1 in complex with hydroxamic acid-based inhibitor 9f
Descriptor: M1 family aminopeptidase, MAGNESIUM ION, ZINC ION, ...
Authors:Drinkwater, N, McGowan, S.
Deposit date:2015-05-19
Release date:2016-03-30
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Potent dual inhibitors of Plasmodium falciparum M1 and M17 aminopeptidases through optimization of S1 pocket interactions.
Eur.J.Med.Chem., 110, 2016
4OO2
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BU of 4oo2 by Molmil
Streptomyces globisporus C-1027 FAD dependent (S)-3-chloro-β-tyrosine-S-SgcC2 C-5 hydroxylase SgcC apo form
Descriptor: CALCIUM ION, Chlorophenol-4-monooxygenase, GLYCEROL
Authors:Cao, H, Xu, W, Bingman, C.A, Lohman, J.R, Yennamalli, R, Shen, B, Phillips Jr, G.N, Enzyme Discovery for Natural Product Biosynthesis (NatPro)
Deposit date:2014-01-29
Release date:2014-02-12
Last modified:2023-03-22
Method:X-RAY DIFFRACTION (2.63 Å)
Cite:Crystal Structures of SgcE6 and SgcC, the Two-Component Monooxygenase That Catalyzes Hydroxylation of a Carrier Protein-Tethered Substrate during the Biosynthesis of the Enediyne Antitumor Antibiotic C-1027 in Streptomyces globisporus.
Biochemistry, 55, 2016
4B3O
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BU of 4b3o by Molmil
Structures of HIV-1 RT and RNA-DNA Complex Reveal a Unique RT Conformation and Substrate Interface
Descriptor: (-)-6-CHLORO-4-CYCLOPROPYLETHYNYL-4-TRIFLUOROMETHYL-1,4-DIHYDRO-2H-3,1-BENZOXAZIN-2-ONE, 5'-D(*CP*GP*TP*AP*TP*GP*CP*CP*TP*AP*TP*AP*GP*TP *TP*AP*TP*TP*GP*TP*GP*GP*CP*C)-3', 5'-R(*AP*UP*GP*AP*3DRP*GP*GP*CP*CP*AP*CP*AP*AP*UP*AP *AP*CP*UP*AP*UP*AP*GP*GP*CP*AP*UP*A)-3', ...
Authors:Lapkouski, M, Tian, L, Miller, J.T, Le Grice, S.F.J, Yang, W.
Deposit date:2012-07-25
Release date:2013-01-16
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Complexes of HIV-1 RT, Nnrti and RNA/DNA Hybrid Reveal a Structure Compatible with RNA Degradation
Nat.Struct.Mol.Biol., 20, 2013
4OPC
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BU of 4opc by Molmil
Constructing tailored isoprenoid products by structure-guided modification of geranylgeranyl reductase.
Descriptor: (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, Conserved Archaeal protein, DIHYDROFLAVINE-ADENINE DINUCLEOTIDE
Authors:McAndrew, R.P, Kung, Y, Xie, X, Liu, C, Pereira, J.H, Keasling, J.D, Adams, P.D.
Deposit date:2014-02-05
Release date:2014-07-09
Last modified:2014-07-23
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Constructing tailored isoprenoid products by structure-guided modification of geranylgeranyl reductase.
Structure, 22, 2014
4OM8
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BU of 4om8 by Molmil
Crystal structure of 5-formly-3-hydroxy-2-methylpyridine 4-carboxylic acid (FHMPC) 5-dehydrogenase, an NAD+ dependent dismutase.
Descriptor: 3-hydroxybutyryl-coA dehydrogenase, ACETATE ION, BETA-MERCAPTOETHANOL, ...
Authors:Mugo, A.N, Kobayashi, J, Mikami, B, Yagi, T, Ohnishi, K.
Deposit date:2014-01-27
Release date:2015-01-28
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Crystal structure of 5-formyl-3-hydroxy-2-methylpyridine 4-carboxylic acid 5-dehydrogenase, an NAD(+)-dependent dismutase from Mesorhizobium loti
Biochem.Biophys.Res.Commun., 456, 2015

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