8WAR
 
 | | Structure of transcribing complex 8 (TC8), the initially transcribing complex with Pol II positioned 8nt downstream of TSS. | | Descriptor: | Alpha-amanitin, CDK-activating kinase assembly factor MAT1, DNA-directed RNA polymerase II subunit E, ... | | Authors: | Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y. | | Deposit date: | 2023-09-08 | | Release date: | 2023-12-06 | | Last modified: | 2024-01-03 | | Method: | ELECTRON MICROSCOPY (7.2 Å) | | Cite: | Structural visualization of transcription initiation in action.
Science, 382, 2023
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8WAP
 | | Structure of transcribing complex 6 (TC6), the initially transcribing complex with Pol II positioned 6nt downstream of TSS. | | Descriptor: | Alpha-amanitin, CDK-activating kinase assembly factor MAT1, DNA-directed RNA polymerase II subunit E, ... | | Authors: | Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y. | | Deposit date: | 2023-09-08 | | Release date: | 2023-12-06 | | Last modified: | 2024-01-03 | | Method: | ELECTRON MICROSCOPY (5.85 Å) | | Cite: | Structural visualization of transcription initiation in action.
Science, 382, 2023
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8WAS
 | | Structure of transcribing complex 9 (TC9), the initially transcribing complex with Pol II positioned 9nt downstream of TSS. | | Descriptor: | Alpha-amanitin, CDK-activating kinase assembly factor MAT1, DNA-directed RNA polymerase II subunit E, ... | | Authors: | Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y. | | Deposit date: | 2023-09-08 | | Release date: | 2023-12-06 | | Last modified: | 2024-01-03 | | Method: | ELECTRON MICROSCOPY (6.13 Å) | | Cite: | Structural visualization of transcription initiation in action.
Science, 382, 2023
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8WAN
 | | Structure of transcribing complex 4 (TC4), the initially transcribing complex with Pol II positioned 4nt downstream of TSS. | | Descriptor: | Alpha-amanitin, CDK-activating kinase assembly factor MAT1, DNA-directed RNA polymerase II subunit E, ... | | Authors: | Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y. | | Deposit date: | 2023-09-07 | | Release date: | 2023-12-06 | | Last modified: | 2024-01-03 | | Method: | ELECTRON MICROSCOPY (6.07 Å) | | Cite: | Structural visualization of transcription initiation in action.
Science, 382, 2023
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8WAL
 | | Structure of transcribing complex 3 (TC3), the initially transcribing complex with Pol II positioned 3nt downstream of TSS. | | Descriptor: | Alpha-amanitin, CDK-activating kinase assembly factor MAT1, DNA-directed RNA polymerase II subunit E, ... | | Authors: | Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y. | | Deposit date: | 2023-09-07 | | Release date: | 2023-12-06 | | Last modified: | 2024-01-03 | | Method: | ELECTRON MICROSCOPY (8.52 Å) | | Cite: | Structural visualization of transcription initiation in action.
Science, 382, 2023
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8WAO
 | | Structure of transcribing complex 5 (TC5), the initially transcribing complex with Pol II positioned 5nt downstream of TSS. | | Descriptor: | Alpha-amanitin, CDK-activating kinase assembly factor MAT1, DNA-directed RNA polymerase II subunit E, ... | | Authors: | Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y. | | Deposit date: | 2023-09-07 | | Release date: | 2023-12-06 | | Last modified: | 2024-01-03 | | Method: | ELECTRON MICROSCOPY (6.4 Å) | | Cite: | Structural visualization of transcription initiation in action.
Science, 382, 2023
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8WAQ
 | | Structure of transcribing complex 7 (TC7), the initially transcribing complex with Pol II positioned 7nt downstream of TSS. | | Descriptor: | Alpha-amanitin, CDK-activating kinase assembly factor MAT1, DNA-directed RNA polymerase II subunit E, ... | | Authors: | Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y. | | Deposit date: | 2023-09-08 | | Release date: | 2023-12-06 | | Last modified: | 2024-01-03 | | Method: | ELECTRON MICROSCOPY (6.29 Å) | | Cite: | Structural visualization of transcription initiation in action.
Science, 382, 2023
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8WAK
 | | Structure of transcribing complex 2 (TC2), the initially transcribing complex with Pol II positioned 2nt downstream of TSS. | | Descriptor: | Alpha-amanitin, CDK-activating kinase assembly factor MAT1, DNA-directed RNA polymerase II subunit E, ... | | Authors: | Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y. | | Deposit date: | 2023-09-07 | | Release date: | 2023-12-06 | | Last modified: | 2024-01-03 | | Method: | ELECTRON MICROSCOPY (5.47 Å) | | Cite: | Structural visualization of transcription initiation in action.
Science, 382, 2023
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7ENA
 | | TFIID-based PIC-Mediator holo-complex in pre-assembled state (pre-hPIC-MED) | | Descriptor: | CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ... | | Authors: | Chen, X, Qi, Y, Wang, X, Wu, Z, Yin, X, Li, J, Liu, W, Xu, Y. | | Deposit date: | 2021-04-16 | | Release date: | 2021-05-26 | | Last modified: | 2021-06-16 | | Method: | ELECTRON MICROSCOPY (4.07 Å) | | Cite: | Structures of the human Mediator and Mediator-bound preinitiation complex.
Science, 372, 2021
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7ENC
 | | TFIID-based PIC-Mediator holo-complex in fully-assembled state (hPIC-MED) | | Descriptor: | CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ... | | Authors: | Chen, X, Qi, Y, Wang, X, Wu, Z, Yin, X, Li, J, Liu, W, Xu, Y. | | Deposit date: | 2021-04-16 | | Release date: | 2021-05-26 | | Last modified: | 2021-06-16 | | Method: | ELECTRON MICROSCOPY (4.13 Å) | | Cite: | Structures of the human Mediator and Mediator-bound preinitiation complex.
Science, 372, 2021
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7ZS9
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6CND
 | | Yeast RNA polymerase III natural open complex (nOC) | | Descriptor: | DNA (71-MER), DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, ... | | Authors: | Han, Y, He, Y. | | Deposit date: | 2018-03-08 | | Release date: | 2018-08-22 | | Last modified: | 2020-01-08 | | Method: | ELECTRON MICROSCOPY (4.8 Å) | | Cite: | Structural visualization of RNA polymerase III transcription machineries.
Cell Discov, 4, 2018
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6CNB
 | | Yeast RNA polymerase III initial transcribing complex | | Descriptor: | DNA (71-MER), DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, ... | | Authors: | Han, Y, He, Y. | | Deposit date: | 2018-03-08 | | Release date: | 2018-08-22 | | Last modified: | 2020-01-08 | | Method: | ELECTRON MICROSCOPY (4.1 Å) | | Cite: | Structural visualization of RNA polymerase III transcription machineries.
Cell Discov, 4, 2018
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4WV4
 | | Heterodimer of TAF8/TAF10 | | Descriptor: | CHLORIDE ION, GLYCEROL, Transcription initiation factor TFIID subunit 10, ... | | Authors: | Trowitzsch, S. | | Deposit date: | 2014-11-04 | | Release date: | 2015-01-28 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.909 Å) | | Cite: | Cytoplasmic TAF2-TAF8-TAF10 complex provides evidence for nuclear holo-TFIID assembly from preformed submodules.
Nat Commun, 6, 2015
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7EGH
 | | TFIID lobe C subcomplex | | Descriptor: | DNA (45-MER), Transcription initiation factor TFIID subunit 1, Transcription initiation factor TFIID subunit 2, ... | | Authors: | Chen, X, Wu, Z, Li, J, Zhao, D, Xu, Y. | | Deposit date: | 2021-03-24 | | Release date: | 2021-05-12 | | Method: | ELECTRON MICROSCOPY (3.04 Å) | | Cite: | Structural insights into preinitiation complex assembly on core promoters.
Science, 372, 2021
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8IUE
 | | RNA polymerase III pre-initiation complex melting complex 1 | | Descriptor: | DNA (74-MER), DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, ... | | Authors: | Hou, H, Jin, Q, Ren, Y, Wang, Q, Xu, Y. | | Deposit date: | 2023-03-24 | | Release date: | 2023-05-24 | | Last modified: | 2024-07-03 | | Method: | ELECTRON MICROSCOPY (4.1 Å) | | Cite: | Structure of the SNAPc-bound RNA polymerase III preinitiation complex.
Cell Res., 33, 2023
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8IUH
 | | RNA polymerase III pre-initiation complex open complex 1 | | Descriptor: | DNA (81-MER), DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, ... | | Authors: | Hou, H, Jin, Q, Ren, Y, Wang, Q, Xu, Y. | | Deposit date: | 2023-03-24 | | Release date: | 2023-05-24 | | Last modified: | 2024-07-03 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Structure of the SNAPc-bound RNA polymerase III preinitiation complex.
Cell Res., 33, 2023
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8ITY
 | | human RNA polymerase III pre-initiation complex closed DNA 1 | | Descriptor: | DNA (82-MER), DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, ... | | Authors: | Hou, H, Jin, Q, Ren, Y, Wang, Q, Xu, Y. | | Deposit date: | 2023-03-23 | | Release date: | 2023-06-07 | | Last modified: | 2023-07-12 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Structure of the SNAPc-bound RNA polymerase III preinitiation complex.
Cell Res., 33, 2023
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7EGG
 | | TFIID lobe B subcomplex | | Descriptor: | Transcription initiation factor TFIID subunit 10, Transcription initiation factor TFIID subunit 12, Transcription initiation factor TFIID subunit 4, ... | | Authors: | Chen, X, Wu, Z, Li, J, Zhao, D, Xu, Y. | | Deposit date: | 2021-03-24 | | Release date: | 2021-05-05 | | Last modified: | 2024-06-05 | | Method: | ELECTRON MICROSCOPY (2.77 Å) | | Cite: | Structural insights into preinitiation complex assembly on core promoters.
Science, 372, 2021
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7O4J
 | | Yeast RNA polymerase II transcription pre-initiation complex (consensus) | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA-directed RNA polymerase II subunit RPB1, ... | | Authors: | Schilbach, S, Aibara, S, Dienemann, C, Grabbe, F, Cramer, P. | | Deposit date: | 2021-04-06 | | Release date: | 2021-06-16 | | Last modified: | 2024-07-10 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Structure of RNA polymerase II pre-initiation complex at 2.9 angstrom defines initial DNA opening.
Cell, 184, 2021
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7O4I
 | | Yeast RNA polymerase II transcription pre-initiation complex with initial transcription bubble | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA-directed RNA polymerase II subunit RPB1, ... | | Authors: | Schilbach, S, Aibara, S, Dienemann, C, Grabbe, F, Cramer, P. | | Deposit date: | 2021-04-06 | | Release date: | 2021-06-16 | | Last modified: | 2024-07-10 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Structure of RNA polymerase II pre-initiation complex at 2.9 angstrom defines initial DNA opening.
Cell, 184, 2021
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7O75
 | | Yeast RNA polymerase II transcription pre-initiation complex with open promoter DNA | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA-directed RNA polymerase II subunit RPB1, ... | | Authors: | Schilbach, S, Aibara, S, Dienemann, C, Grabbe, F, Cramer, P. | | Deposit date: | 2021-04-13 | | Release date: | 2021-06-16 | | Last modified: | 2024-07-10 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Structure of RNA polymerase II pre-initiation complex at 2.9 angstrom defines initial DNA opening.
Cell, 184, 2021
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7O73
 | | Yeast RNA polymerase II transcription pre-initiation complex with closed distorted promoter DNA | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA-directed RNA polymerase II subunit RPB1, ... | | Authors: | Schilbach, S, Aibara, S, Dienemann, C, Grabbe, F, Cramer, P. | | Deposit date: | 2021-04-12 | | Release date: | 2021-06-16 | | Last modified: | 2024-07-10 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Structure of RNA polymerase II pre-initiation complex at 2.9 angstrom defines initial DNA opening.
Cell, 184, 2021
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7ML0
 | | RNA polymerase II pre-initiation complex (PIC1) | | Descriptor: | BJ4_G0050160.mRNA.1.CDS.1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB3, ... | | Authors: | Yang, C, Fujiwara, R, Kim, H.J, Gorbea Colon, J.J, Steimle, S, Garcia, B.A, Murakami, K. | | Deposit date: | 2021-04-27 | | Release date: | 2022-02-02 | | Last modified: | 2022-02-16 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Structural visualization of de novo transcription initiation by Saccharomyces cerevisiae RNA polymerase II.
Mol.Cell, 82, 2022
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7ML4
 | | RNA polymerase II initially transcribing complex (ITC) | | Descriptor: | BJ4_G0050160.mRNA.1.CDS.1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB3, ... | | Authors: | Yang, C, Fujiwara, R, Kim, H.J, Gorbea Colon, J.J, Steimle, S, Garcia, B.A, Murakami, K. | | Deposit date: | 2021-04-27 | | Release date: | 2022-02-02 | | Last modified: | 2022-03-09 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Structural visualization of de novo transcription initiation by Saccharomyces cerevisiae RNA polymerase II.
Mol.Cell, 82, 2022
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