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1UGH
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BU of 1ugh by Molmil
CRYSTAL STRUCTURE OF HUMAN URACIL-DNA GLYCOSYLASE IN COMPLEX WITH A PROTEIN INHIBITOR: PROTEIN MIMICRY OF DNA
Descriptor: PROTEIN (URACIL-DNA GLYCOSYLASE INHIBITOR), PROTEIN (URACIL-DNA GLYCOSYLASE)
Authors:Mol, C.D, Arvai, A.S, Sanderson, R.J, Slupphaug, G, Kavli, B, Krokan, H.E, Mosbaugh, D.W, Tainer, J.A.
Deposit date:1999-02-05
Release date:1999-02-16
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of human uracil-DNA glycosylase in complex with a protein inhibitor: protein mimicry of DNA.
Cell(Cambridge,Mass.), 82, 1995
3O8Y
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BU of 3o8y by Molmil
Stable-5-Lipoxygenase
Descriptor: Arachidonate 5-lipoxygenase, FE (II) ION
Authors:Newcomer, M.E, Gilbert, N.C, Bartlett, S.G, Waight, M.T, Neau, D.B, Boeglin, W.E, Brash, A.R.
Deposit date:2010-08-03
Release date:2011-01-19
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.389 Å)
Cite:The structure of human 5-lipoxygenase.
Science, 331, 2011
5F4Q
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BU of 5f4q by Molmil
Crystal structure of the human egg surface protein Juno
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, GLYCEROL, ...
Authors:Aydin, H, Sultana, A, Lee, J.E.
Deposit date:2015-12-03
Release date:2016-06-15
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Molecular architecture of the human sperm IZUMO1 and egg JUNO fertilization complex.
Nature, 534, 2016
4HRT
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BU of 4hrt by Molmil
Scapharca tetrameric hemoglobin, unliganded
Descriptor: Globin-2 A chain, Hemoglobin B chain, PHOSPHATE ION, ...
Authors:Royer, W.E.
Deposit date:2012-10-28
Release date:2012-12-12
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.46 Å)
Cite:Tertiary and Quaternary Allostery in Tetrameric Hemoglobin from Scapharca inaequivalvis.
Biochemistry, 52, 2013
6DV6
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BU of 6dv6 by Molmil
Structure of the Salmonella SPI-1 type III secretion injectisome secretin InvG (residues 176-end) in the open gate state
Descriptor: Protein InvG
Authors:Hu, J, Worrall, L.J, Vuckovic, M, Atkinson, C.E, Strynadka, N.C.J.
Deposit date:2018-06-22
Release date:2018-10-03
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Cryo-EM analysis of the T3S injectisome reveals the structure of the needle and open secretin.
Nat Commun, 9, 2018
2DRM
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BU of 2drm by Molmil
Acanthamoeba myosin I SH3 domain bound to Acan125
Descriptor: 18-mer peptide from Acan125, Acanthamoeba Myosin IB, GLYCEROL, ...
Authors:Houdusse, A, Bahloul, A, Ostap, E.M.
Deposit date:2006-06-09
Release date:2007-05-29
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:The crystal structure of the SH3 domain of Acanthamoeba myosin IB bound to Acan125
To be Published
3IK9
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BU of 3ik9 by Molmil
Human GST A1-1-GIMF with GSDHN
Descriptor: (S)-2-amino-5-((R)-1-(carboxymethylamino)-3-((3S,4R)-1,4-dihydroxynonan-3-ylthio)-1-oxopropan-2-ylamino)-5-oxopentanoic acid, Glutathione S-transferase A1
Authors:Balogh, L.M, Le Trong, I, Atkins, W.M, Stenkamp, R.E.
Deposit date:2009-08-05
Release date:2010-06-23
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Substrate specificity combined with stereopromiscuity in glutathione transferase A4-4-dependent metabolism of 4-hydroxynonenal.
Biochemistry, 49, 2010
4I2Y
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BU of 4i2y by Molmil
Crystal Structure of the genetically encoded calcium indicator RGECO1
Descriptor: CALCIUM ION, RGECO1
Authors:Akerboom, J, Looger, L.L, Schreiter, E.R.
Deposit date:2012-11-23
Release date:2013-07-24
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Genetically encoded calcium indicators for multi-color neural activity imaging and combination with optogenetics.
Front Mol Neurosci, 6, 2013
4MZL
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BU of 4mzl by Molmil
Crystal Structure of MTIP from Plasmodium falciparum in complex with HBS myoA, a hydrogen bond surrogate myoA helix mimetic
Descriptor: Myosin A tail domain interacting protein, hydrogen bond surrogate (HBS) myoA helix mimetic
Authors:Douse, C.H, Garnett, J.A, Maas, S.J, Cota, E, Tate, E.W.
Deposit date:2013-09-30
Release date:2013-11-06
Last modified:2023-06-07
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Crystal Structures of Stapled and Hydrogen Bond Surrogate Peptides Targeting a Fully Buried Protein-Helix Interaction.
Acs Chem.Biol., 8, 2014
3O4T
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BU of 3o4t by Molmil
Crystal Structure of HePTP with an Open WPD Loop and Partially Depleted Active Site
Descriptor: D(-)-TARTARIC ACID, GLYCEROL, SULFATE ION, ...
Authors:Critton, D.A, Page, R.
Deposit date:2010-07-27
Release date:2010-11-24
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Visualizing active-site dynamics in single crystals of HePTP: opening of the WPD loop involves coordinated movement of the E loop.
J.Mol.Biol., 405, 2011
4Q4I
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BU of 4q4i by Molmil
Crystal structure of E.coli aminopeptidase N in complex with amastatin
Descriptor: Amastatin, Aminopeptidase N, GLYCEROL, ...
Authors:Reddi, R, Ganji, R.J, Addlagatta, A.
Deposit date:2014-04-14
Release date:2015-04-15
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:Structural basis for the inhibition of M1 family aminopeptidases by the natural product actinonin: Crystal structure in complex with E. coli aminopeptidase N.
Protein Sci., 24, 2015
4Q3F
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BU of 4q3f by Molmil
Human D-DT complexed with tartrate
Descriptor: D-dopachrome decarboxylase, L(+)-TARTARIC ACID
Authors:Rajasekaran, D, Lolis, E.
Deposit date:2014-04-11
Release date:2014-06-04
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Targeting distinct tautomerase sites of D-DT and MIF with a single molecule for inhibition of neutrophil lung recruitment.
Faseb J., 28, 2014
4I5O
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BU of 4i5o by Molmil
Crystal Structure of W-W-R ClpX Hexamer
Descriptor: ATP-dependent Clp protease ATP-binding subunit ClpX, SULFATE ION
Authors:Glynn, S.E, Nager, A.R, Stinson, B.S, Schmitz, K.R, Baker, T.A, Sauer, R.T.
Deposit date:2012-11-28
Release date:2013-05-15
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (4.4787 Å)
Cite:Nucleotide Binding and Conformational Switching in the Hexameric Ring of a AAA+ Machine.
Cell(Cambridge,Mass.), 153, 2013
4I6R
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BU of 4i6r by Molmil
High Resolution Crystal Structure of the Wild-Type Restriction-Modification Controller Protein C.Esp1396I (Triclinic form)
Descriptor: GLYCEROL, Regulatory protein, SULFATE ION
Authors:Martin, R.N.A, McGeehan, J.E, Kneale, G.G.
Deposit date:2012-11-30
Release date:2013-11-13
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.38 Å)
Cite:Structural and Mutagenic Analysis of the RM Controller Protein C.Esp1396I.
Plos One, 9, 2014
1KRC
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BU of 1krc by Molmil
CRYSTAL STRUCTURE OF KLEBSIELLA AEROGENES UREASE, ITS APOENZYME AND TWO ACTIVE SITE MUTANTS
Descriptor: CARBON DIOXIDE, NICKEL (II) ION, UREASE
Authors:Jabri, E, Karplus, P.A.
Deposit date:1995-06-20
Release date:1995-10-15
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structures of the Klebsiella aerogenes urease apoenzyme and two active-site mutants.
Biochemistry, 35, 1996
1F98
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BU of 1f98 by Molmil
CRYSTAL STRUCTURE OF THE PHOTOACTIVE YELLOW PROTEIN MUTANT T50V
Descriptor: 4'-HYDROXYCINNAMIC ACID, PHOTOACTIVE YELLOW PROTEIN
Authors:Brudler, R, Meyer, T.E, Genick, U.K, Tollin, G, Getzoff, E.D.
Deposit date:2000-07-07
Release date:2000-07-21
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (1.15 Å)
Cite:Coupling of hydrogen bonding to chromophore conformation and function in photoactive yellow protein.
Biochemistry, 39, 2000
3IG5
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BU of 3ig5 by Molmil
Saccharomyces cerevisiae glutamate cysteine ligase in complex with Mg2+ and L-glutamate
Descriptor: GLUTAMIC ACID, Glutamate-cysteine ligase, MAGNESIUM ION, ...
Authors:Biterova, E, Barycki, J.J.
Deposit date:2009-07-27
Release date:2009-09-01
Last modified:2012-12-26
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Mechanistic details of glutathione biosynthesis revealed by crystal structures of Saccharomyces cerevisiae glutamate cysteine ligase.
J.Biol.Chem., 284, 2009
6DLE
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BU of 6dle by Molmil
Crystal structure of IgLON5 homodimer
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, IgLON family member 5
Authors:Ranaivoson, F.M, Turk, L.S, Ozkan, E, Montelione, G.T, Comoletti, D.
Deposit date:2018-06-01
Release date:2019-04-10
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.994 Å)
Cite:Structure of a heterodimer of neuronal cell surface proteins
Structure, 2019
6DLZ
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BU of 6dlz by Molmil
Open state GluA2 in complex with STZ after micelle signal subtraction
Descriptor: CYCLOTHIAZIDE, GLUTAMIC ACID, Glutamate receptor 2,Voltage-dependent calcium channel gamma-2 subunit
Authors:Twomey, E.C, Yelshanskaya, M.V, Vassilevski, A.A, Sobolevsky, A.I.
Deposit date:2018-06-04
Release date:2018-08-22
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Mechanisms of Channel Block in Calcium-Permeable AMPA Receptors.
Neuron, 99, 2018
3FPX
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BU of 3fpx by Molmil
Native fungus laccase from Trametes hirsuta
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, COPPER (II) ION, ...
Authors:Polyakov, K.M, Fedorova, T.V, Stepanova, E.V, Cherkashin, E.A, Kurzeev, S.A, Strokopytov, B.V, Lamzin, V.S, Koroleva, O.V.
Deposit date:2009-01-06
Release date:2009-01-27
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of native laccase from Coriolus hirsutus at 1.8 A resolution
To be Published
1FCD
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BU of 1fcd by Molmil
THE STRUCTURE OF FLAVOCYTOCHROME C SULFIDE DEHYDROGENASE FROM A PURPLE PHOTOTROPHIC BACTERIUM CHROMATIUM VINOSUM AT 2.5 ANGSTROMS RESOLUTION
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, FLAVOCYTOCHROME C SULFIDE DEHYDROGENASE (CYTOCHROME SUBUNIT), FLAVOCYTOCHROME C SULFIDE DEHYDROGENASE (FLAVIN-BINDING SUBUNIT), ...
Authors:Chen, Z.W, Koh, M, Van Driessche, G, Van Beeumen, J.J, Bartsch, R.G, Meyer, T.E, Cusanovich, M.A, Mathews, F.S.
Deposit date:1994-08-18
Release date:1994-11-01
Last modified:2021-03-10
Method:X-RAY DIFFRACTION (2.53 Å)
Cite:The structure of flavocytochrome c sulfide dehydrogenase from a purple phototrophic bacterium.
Science, 266, 1994
5C0Z
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BU of 5c0z by Molmil
The structure of oxidized rat cytochrome c at 1.13 angstroms resolution
Descriptor: Cytochrome c, somatic, HEME C, ...
Authors:Edwards, B.F.P, Mahapatra, G, Vaishnav, A.A, Brunzelle, J.S, Huttemann, M.
Deposit date:2015-06-12
Release date:2016-09-21
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.1236 Å)
Cite:Serine-47 phosphorylation of cytochromecin the mammalian brain regulates cytochromecoxidase and caspase-3 activity.
Faseb J., 2019
3O69
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BU of 3o69 by Molmil
Structure of the E100A E.coli GDP-mannose hydrolase (yffh) in complex with Mg++
Descriptor: CHLORIDE ION, DI(HYDROXYETHYL)ETHER, GDP-mannose pyrophosphatase nudK, ...
Authors:Amzel, L.M, Gabelli, S.B, Boto, A.N.
Deposit date:2010-07-28
Release date:2011-05-11
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural studies of the Nudix GDP-mannose hydrolase from E. coli reveals a new motif for mannose recognition.
Proteins, 79, 2011
1L89
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BU of 1l89 by Molmil
SIMILAR HYDROPHOBIC REPLACEMENTS OF LEU 99 AND PHE 153 WITHIN THE CORE OF T4 LYSOZYME HAVE DIFFERENT STRUCTURAL AND THERMODYNAMIC CONSEQUENCES
Descriptor: BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME
Authors:Eriksson, A.E, Matthews, B.W.
Deposit date:1992-01-21
Release date:1993-10-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Similar hydrophobic replacements of Leu99 and Phe153 within the core of T4 lysozyme have different structural and thermodynamic consequences.
J.Mol.Biol., 229, 1993
4QBM
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BU of 4qbm by Molmil
Crystal structure of human BAZ2A bromodomain in complex with a diacetylated histone 4 peptide (H4K16acK20ac)
Descriptor: 1,2-ETHANEDIOL, Bromodomain adjacent to zinc finger domain protein 2A, histone H4 peptide with sequence Gly-Ala-Lys(ac)-Arg-His-Arg-Lys(ac)-Val-Leu
Authors:Tallant, C, Nunez-Alonso, G, Picaud, S, Filippakopoulos, P, Krojer, T, Williams, E, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC)
Deposit date:2014-05-08
Release date:2014-05-21
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Molecular basis of histone tail recognition by human TIP5 PHD finger and bromodomain of the chromatin remodeling complex NoRC.
Structure, 23, 2015

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