3NDE
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3N89
| KH domains | Descriptor: | Defective in germ line development protein 3, isoform a | Authors: | Nakel, K, Hartung, S.A, Bonneau, F, Eckmann, C.R, Conti, E. | Deposit date: | 2010-05-28 | Release date: | 2010-09-22 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.789 Å) | Cite: | Four KH domains of the C. elegans Bicaudal-C ortholog GLD-3 form a globular structural platform. Rna, 16, 2010
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4EAK
| Co-crystal structure of an AMPK core with ATP | Descriptor: | 5'-AMP-activated protein kinase catalytic subunit alpha-1, 5'-AMP-activated protein kinase subunit beta-1, 5'-AMP-activated protein kinase subunit gamma-1, ... | Authors: | Chen, L, Wang, J, Zhang, Y.-Y, Yan, S.F, Neumann, D, Schlattner, U, Wang, Z.-X, Wu, J.-W. | Deposit date: | 2012-03-22 | Release date: | 2012-06-06 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | AMP-activated protein kinase undergoes nucleotide-dependent conformational changes Nat.Struct.Mol.Biol., 19, 2012
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3NCK
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3EFL
| Crystal structure of the VEGFR2 kinase domain in complex with motesanib | Descriptor: | N-(3,3-dimethyl-2,3-dihydro-1H-indol-6-yl)-2-[(pyridin-4-ylmethyl)amino]pyridine-3-carboxamide, Vascular endothelial growth factor receptor 2 | Authors: | Kim, J.L, Whittington, D.A, Long, A.M, Rose, P, Gu, Y, Zhao, H. | Deposit date: | 2008-09-09 | Release date: | 2009-09-15 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Discovery of Motesanib To be Published
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4EMY
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3EIK
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3EHT
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6YGB
| Crystal structure of the NatC complex bound to CoA | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, COENZYME A, ... | Authors: | Grunwald, S, Hopf, L, Bock-Bierbaum, T, Lally, C.C, Spahn, C.M.T, Daumke, O. | Deposit date: | 2020-03-27 | Release date: | 2020-10-28 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.451 Å) | Cite: | Divergent architecture of the heterotrimeric NatC complex explains N-terminal acetylation of cognate substrates. Nat Commun, 11, 2020
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6YLO
| mTurquoise2 - Directionality of Optical Properties of Fluorescent Proteins | Descriptor: | POTASSIUM ION, TETRAETHYLENE GLYCOL, mTurquoise2_C2221 | Authors: | Myskova, J, Rybakova, O, Brynda, J, Lazar, J. | Deposit date: | 2020-04-07 | Release date: | 2020-12-16 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Directionality of light absorption and emission in representative fluorescent proteins. Proc.Natl.Acad.Sci.USA, 117, 2020
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3ENQ
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6YPT
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4ESK
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3EP0
| Methyltransferase domain of human PR domain-containing protein 12 | Descriptor: | PR domain zinc finger protein 12 | Authors: | Amaya, M.F, Zeng, H, Loppnau, P, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Botchkarev, A, Min, J, Plotnikov, A.N, Wu, H, Structural Genomics Consortium (SGC) | Deposit date: | 2008-09-29 | Release date: | 2008-11-04 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The crystal structure of methyltransferase domain of human PR
Domain-containing protein 12. To be Published
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4EKB
| Initial Thaumatin Structure for Radiation Damage Experiment at 100 K | Descriptor: | L(+)-TARTARIC ACID, Thaumatin-1 | Authors: | Warkentin, M, Badeau, R, Hopkins, J.B, Thorne, R.E. | Deposit date: | 2012-04-09 | Release date: | 2012-08-29 | Last modified: | 2013-01-23 | Method: | X-RAY DIFFRACTION (1.52 Å) | Cite: | Spatial distribution of radiation damage to crystalline proteins at 25-300 K. Acta Crystallogr.,Sect.D, 68, 2012
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6VTP
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6VTR
| Crystal structure of G16S human Galectin-7 mutant | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLYCEROL, Galectin-7 | Authors: | Pham, N.T.H, Calmettes, C, Doucet, N. | Deposit date: | 2020-02-13 | Release date: | 2021-08-25 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Perturbing dimer interactions and allosteric communication modulates the immunosuppressive activity of human galectin-7. J.Biol.Chem., 297, 2021
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4EPU
| Ang1 fibrinogen-related domain (FReD) | Descriptor: | Angiopoietin-1, CALCIUM ION | Authors: | Yeykal, C.C, Adams, E.J. | Deposit date: | 2012-04-17 | Release date: | 2013-04-17 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.098 Å) | Cite: | Biochemical and structural characterization of the Ang1 fibrinogen-related domain To be Published
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4EW1
| High resolution structure of human glycinamide ribonucleotide transformylase in apo form. | Descriptor: | PHOSPHATE ION, SULFATE ION, Trifunctional purine biosynthetic protein adenosine-3 | Authors: | Connelly, S, DeMartino, K, Boger, D.L, Wilson, I.A. | Deposit date: | 2012-04-26 | Release date: | 2013-07-31 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.522 Å) | Cite: | Biological and Structural Evaluation of 10R- and 10S-Methylthio-DDACTHF Reveals a New Role for Sulfur in Inhibition of Glycinamide Ribonucleotide Transformylase. Biochemistry, 52, 2013
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3NC8
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3NFP
| Crystal structure of the Fab fragment of therapeutic antibody daclizumab in complex with IL-2Ra (CD25) ectodomain | Descriptor: | Heavy chain of Fab fragment of daclizumab, Interleukin-2 receptor subunit alpha, Light chain of Fab fragment of daclizumab | Authors: | Yang, H, Wang, J, Du, J, Zhong, C, Guo, Y, Ding, J. | Deposit date: | 2010-06-10 | Release date: | 2010-09-15 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.86 Å) | Cite: | Structural basis of immunosuppression by the therapeutic antibody daclizumab Cell Res., 20, 2010
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4ETY
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4EVD
| Crystal Structure HP-NAP from strain YS29 cadmium loaded (Cocrystallization 50mM) | Descriptor: | CADMIUM ION, Neutrophil-activating protein | Authors: | Yokoyama, H, Tsuruta, O, Akao, N, Fujii, S. | Deposit date: | 2012-04-26 | Release date: | 2012-06-27 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of Helicobacter pylori neutrophil-activating protein with a di-nuclear ferroxidase center in a zinc or cadmium-bound form Biochem.Biophys.Res.Commun., 422, 2012
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4EW3
| The structure of human glycinamide ribonucleotide transformylase in complex with 10R-methylthio-DDATHF. | Descriptor: | N-({4-[(1R)-4-(2,4-diamino-6-oxo-1,6-dihydropyrimidin-5-yl)-1-(methylsulfanyl)butyl]phenyl}carbonyl)-L-glutamic acid, PHOSPHATE ION, SULFATE ION, ... | Authors: | Connelly, S, DeMartino, K, Boger, D.L, Wilson, I.A. | Deposit date: | 2012-04-26 | Release date: | 2013-07-31 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.702 Å) | Cite: | Biological and Structural Evaluation of 10R- and 10S-Methylthio-DDACTHF Reveals a New Role for Sulfur in Inhibition of Glycinamide Ribonucleotide Transformylase. Biochemistry, 52, 2013
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6YDK
| Substrate-free P146A variant of beta-phosphoglucomutase from Lactococcus lactis | Descriptor: | Beta-phosphoglucomutase, MAGNESIUM ION | Authors: | Wood, H.P, Cruz-Navarrete, F.A, Baxter, N.J, Trevitt, C.R, Robertson, A.J, Dix, S.R, Hounslow, A.M, Cliff, M.J, Waltho, J.P. | Deposit date: | 2020-03-20 | Release date: | 2020-10-28 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.02 Å) | Cite: | Allomorphy as a mechanism of post-translational control of enzyme activity. Nat Commun, 11, 2020
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