3BI2
| |
2H8K
| Human Sulfotranferase SULT1C3 in complex with PAP | Descriptor: | ADENOSINE-3'-5'-DIPHOSPHATE, SULT1C3 splice variant d | Authors: | Tempel, W, Dombrovski, L, Loppnau, P, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC) | Deposit date: | 2006-06-07 | Release date: | 2006-06-20 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structural and chemical profiling of the human cytosolic sulfotransferases. Plos Biol., 5, 2007
|
|
2H70
| Crystal Structure of Thioredoxin Mutant D9E in Hexagonal (p61) Space Group | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, Thioredoxin | Authors: | Gavira, J.A, Godoy-Ruiz, R, Ibarra-Molero, B, Sanchez-Ruiz, J.M. | Deposit date: | 2006-06-01 | Release date: | 2007-05-15 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | A stability pattern of protein hydrophobic mutations that reflects evolutionary structural optimization. Biophys.J., 89, 2005
|
|
3BIY
| Crystal structure of p300 histone acetyltransferase domain in complex with a bisubstrate inhibitor, Lys-CoA | Descriptor: | BROMIDE ION, Histone acetyltransferase p300, [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]methyl (3R,20R)-20-carbamoyl-3-hydroxy-2,2-dimethyl-4,8,14,22-tetraoxo-12-thia-5,9,15,21-tetraazatricos-1-yl dihydrogen diphosphate | Authors: | Liu, X, Wang, L, Zhao, K, Thompson, P.R, Hwang, Y, Marmorstein, R, Cole, P.A. | Deposit date: | 2007-12-02 | Release date: | 2008-02-12 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | The structural basis of protein acetylation by the p300/CBP transcriptional coactivator Nature, 451, 2008
|
|
2HAG
| |
4RXD
| |
3B2I
| Iodide derivative of human LFABP | Descriptor: | Fatty acid-binding protein, liver, IODIDE ION, ... | Authors: | Sharma, A, Yogavel, M, Sharma, A. | Deposit date: | 2011-08-03 | Release date: | 2012-07-11 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | Utility of anion and cation combinations for phasing of protein structures. J.Struct.Funct.Genom., 13, 2012
|
|
2HCF
| |
2H7G
| Structure of variola topoisomerase non-covalently bound to DNA | Descriptor: | 5'-D(*TP*AP*AP*TP*AP*AP*GP*GP*GP*CP*GP*AP*CP*A)-3', 5'-D(*TP*TP*GP*TP*CP*GP*CP*CP*CP*TP*TP*A)-3', DNA topoisomerase 1 | Authors: | Perry, K, Hwang, Y, Bushman, F.D, Van Duyne, G.D. | Deposit date: | 2006-06-02 | Release date: | 2006-08-15 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural basis for specificity in the poxvirus topoisomerase. Mol.Cell, 23, 2006
|
|
3BAS
| |
3B7T
| [E296Q]LTA4H in complex with Arg-Ala-Arg substrate | Descriptor: | IMIDAZOLE, Leukotriene A-4 hydrolase, RAR peptide, ... | Authors: | Tholander, F, Haeggstrom, J, Thunnissen, M, Muroya, A, Roques, B.-P, Fournie-Zaluski, M.-C. | Deposit date: | 2007-10-31 | Release date: | 2008-09-16 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure-based dissection of the active site chemistry of leukotriene a4 hydrolase: implications for m1 aminopeptidases and inhibitor design. Chem.Biol., 15, 2008
|
|
3BEV
| |
4TPO
| High-resolution structure of TxtE with bound tryptophan substrate | Descriptor: | GLYCEROL, PROTOPORPHYRIN IX CONTAINING FE, Putative P450-like protein, ... | Authors: | Cahn, J.K.B, Dodani, S.C, Brinkmann-Chen, S, Heinsich, T, McIntosh, J.A, Arnold, F.H. | Deposit date: | 2014-06-08 | Release date: | 2014-09-10 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.225 Å) | Cite: | Structural, Functional, and Spectroscopic Characterization of the Substrate Scope of the Novel Nitrating Cytochrome P450 TxtE. Chembiochem, 15, 2014
|
|
2HBA
| Crystal Structure of N-terminal Domain of Ribosomal Protein L9 (NTL9) K12M | Descriptor: | 50S ribosomal protein L9, CHLORIDE ION, IMIDAZOLE, ... | Authors: | Cho, J.-H, Kim, E.Y, Schindelin, H, Raleigh, D.P. | Deposit date: | 2006-06-14 | Release date: | 2007-05-29 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.25 Å) | Cite: | Energetically significant networks of coupled interactions within an unfolded protein. Proc.Natl.Acad.Sci.USA, 111, 2014
|
|
3BKR
| |
3CCT
| Thermodynamic and structure guided design of statin hmg-coa reductase inhibitors | Descriptor: | (3R,5R)-7-[2-(4-fluorophenyl)-4-[(2-hydroxyphenyl)carbamoyl]-5-(1-methylethyl)-3-phenyl-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoic acid, 3-hydroxy-3-methylglutaryl-coenzyme A reductase | Authors: | Pavlovsky, A, Sarver, R.W, Harris, M.S, Finzel, B.C. | Deposit date: | 2008-02-26 | Release date: | 2008-06-17 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.12 Å) | Cite: | Thermodynamic and structure guided design of statin based inhibitors of 3-hydroxy-3-methylglutaryl coenzyme a reductase. J.Med.Chem., 51, 2008
|
|
3BNI
| Crystal structure of TetR-family transcriptional regulator from Streptomyces coelicolor | Descriptor: | Putative TetR-family transcriptional regulator, TETRAETHYLENE GLYCOL | Authors: | Osipiuk, J, Xu, X, Gu, J, Savchenko, A, Edwards, A.M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2007-12-14 | Release date: | 2007-12-25 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | X-ray crystal structure of TetR-family transcriptional regulator from Streptomyces coelicolor. To be Published
|
|
2HEH
| Crystal Structure of the KIF2C motor domain | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, KIF2C protein, MAGNESIUM ION, ... | Authors: | Wang, J, Shen, Y, Tempel, W, Landry, R, Arrowsmith, C.H, Edwards, A.M, Sundstrom, M, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) | Deposit date: | 2006-06-21 | Release date: | 2006-07-18 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Crystal structure of the kif2c motor domain to be published
|
|
2HT9
| The structure of dimeric human glutaredoxin 2 | Descriptor: | 12-mer peptide, FE2/S2 (INORGANIC) CLUSTER, GLUTATHIONE, ... | Authors: | Johansson, C, Smee, C, Kavanagh, K.L, Debreczeni, J, von Delft, F, Gileadi, O, Arrowsmith, C, Weigelt, J, Edwards, A, Sundstrom, M, Oppermann, U, Structural Genomics Consortium (SGC) | Deposit date: | 2006-07-25 | Release date: | 2006-08-29 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Reversible sequestration of active site cysteines in a 2Fe-2S-bridged dimer provides a mechanism for glutaredoxin 2 regulation in human mitochondria J.Biol.Chem., 282, 2007
|
|
2HTH
| Structural basis for ubiquitin recognition by the human EAP45/ESCRT-II GLUE domain | Descriptor: | Ubiquitin, Vacuolar protein sorting protein 36 | Authors: | Alam, S.L, Whitby, F.G, Hill, C.P, Sundquist, W.I. | Deposit date: | 2006-07-25 | Release date: | 2006-10-24 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural basis for ubiquitin recognition by the human ESCRT-II EAP45 GLUE domain. Nat.Struct.Mol.Biol., 13, 2006
|
|
3BQY
| Crystal structure of a possible TetR family transcriptional regulator from Streptomyces coelicolor A3(2). | Descriptor: | ACETIC ACID, PHOSPHATE ION, Putative TetR family transcriptional regulator | Authors: | Cuff, M.E, Skarina, T, Kagan, O, Edwards, A.M, Savchenko, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2007-12-20 | Release date: | 2008-01-15 | Last modified: | 2017-10-25 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structure of a possible TetR family transcriptional regulator from Streptomyces coelicolor A3(2). TO BE PUBLISHED
|
|
1VJI
| Gene Product of At1g76680 from Arabidopsis thaliana | Descriptor: | 12-oxophytodienoate reductase (OPR1), FLAVIN MONONUCLEOTIDE | Authors: | Wesenberg, G.E, Smith, D.W, Phillips Jr, G.N, Johnson, K.A, Bingman, C.A, Center for Eukaryotic Structural Genomics (CESG) | Deposit date: | 2004-02-24 | Release date: | 2004-03-16 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.003 Å) | Cite: | X-ray structure of Arabidopsis At1g77680, 12-oxophytodienoate reductase isoform 1. Proteins, 61, 2005
|
|
2HQ9
| |
3BU1
| Crystal structure of monomine-histamine complex | Descriptor: | HISTAMINE, Lipocalin, SULFATE ION | Authors: | Mans, B.J, Ribeiro, J.M, Andersen, J.F. | Deposit date: | 2007-12-31 | Release date: | 2008-04-01 | Last modified: | 2017-10-25 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Structure, function, and evolution of biogenic amine-binding proteins in soft ticks. J.Biol.Chem., 283, 2008
|
|
2HN1
| |