4KU3
| |
4KTI
| Crystal Structure of C143A Xathomonas campestris OleA | Descriptor: | 3-oxoacyl-[ACP] synthase III | Authors: | Goblirsch, B.R. | Deposit date: | 2013-05-20 | Release date: | 2014-07-23 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.839 Å) | Cite: | Substrate Trapping in Crystals of the Thiolase OleA Identifies Three Channels That Enable Long Chain Olefin Biosynthesis. J.Biol.Chem., 291, 2016
|
|
2G9W
| Crystal Structure of Rv1846c, a Putative Transcriptional Regulatory Protein of Mycobacterium Tuberculosis | Descriptor: | CHLORIDE ION, conserved hypothetical protein | Authors: | Saul, F.A, Haouz, A, Fiez-Vandal, C, Shepard, W, Alzari, P.M. | Deposit date: | 2006-03-07 | Release date: | 2007-03-13 | Last modified: | 2021-10-20 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Genome-wide regulon and crystal structure of BlaI (Rv1846c) from Mycobacterium tuberculosis Mol.Microbiol., 71, 2009
|
|
4KTM
| Crystal Structure of C143S Xanthomonas campestris OleA | Descriptor: | 3-oxoacyl-[ACP] synthase III, DI(HYDROXYETHYL)ETHER, PHOSPHATE ION | Authors: | Goblirsch, B.R. | Deposit date: | 2013-05-20 | Release date: | 2014-07-23 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.36 Å) | Cite: | Substrate Trapping in Crystals of the Thiolase OleA Identifies Three Channels That Enable Long Chain Olefin Biosynthesis. J.Biol.Chem., 291, 2016
|
|
4KU5
| |
5WVH
| |
5WVF
| |
8W6P
| Crystal structure of dimeric murine SMPDL3A | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Acid sphingomyelinase-like phosphodiesterase 3a, ... | Authors: | Zhang, C, Liu, P, Fan, S, Hou, Y. | Deposit date: | 2023-08-29 | Release date: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.91 Å) | Cite: | SMPDL3A is a cGAMP-degrading enzyme induced by LXR-mediated lipid metabolism to restrict cGAS-STING DNA sensing. Immunity, 56, 2023
|
|
8W6R
| murine SMPDL3A bound to sulfate | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Acid sphingomyelinase-like phosphodiesterase 3a, ... | Authors: | Zhang, C, Liu, P, Fan, S. | Deposit date: | 2023-08-29 | Release date: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | SMPDL3A is a cGAMP-degrading enzyme induced by LXR-mediated lipid metabolism to restrict cGAS-STING DNA sensing. Immunity, 56, 2023
|
|
5L02
| S324T variant of B. pseudomallei KatG | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, Catalase-peroxidase, PHOSPHATE ION, ... | Authors: | Loewen, P.C. | Deposit date: | 2016-07-26 | Release date: | 2016-08-10 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural characterization of the Ser324Thr variant of the catalase-peroxidase (KatG) from Burkholderia pseudomallei J. Mol. Biol., 345, 2005
|
|
6WJA
| |
6WJB
| UDP-GlcNAc C4-epimerase from Pseudomonas protegens in complex with NAD and UDP-GlcNAc | Descriptor: | NAD-dependent epimerase/dehydratase family protein, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE | Authors: | Marmont, L.S, Pfoh, R, Robinson, H, Howell, P.L. | Deposit date: | 2020-04-13 | Release date: | 2020-07-08 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | PelX is a UDP-N-acetylglucosamine C4-epimerase involved in Pel polysaccharide-dependent biofilm formation. J.Biol.Chem., 295, 2020
|
|
6WJ9
| UDP-GlcNAc C4-epimerase mutant S121A/Y146F from Pseudomonas protegens in complex with UDP-GlcNAc | Descriptor: | NAD-dependent epimerase/dehydratase family protein, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE | Authors: | Marmont, L.S, Willams, R.J, Whitney, J.C, Whitfield, G.B, Robinson, H, Parsek, M.R, Nitz, M, Harrison, J.J, Howell, P.L. | Deposit date: | 2020-04-13 | Release date: | 2020-07-08 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.11 Å) | Cite: | PelX is a UDP-N-acetylglucosamine C4-epimerase involved in Pel polysaccharide-dependent biofilm formation. J.Biol.Chem., 295, 2020
|
|
6XOS
| |
6XOU
| |
6XOV
| |
6XOT
| |
8CIE
| Crystal structure of the human CDKL5 kinase domain with compound YL-354 | Descriptor: | 4-[[3,5-bis(fluoranyl)phenyl]carbonylamino]-~{N}-piperidin-4-yl-1~{H}-pyrazole-3-carboxamide, Cyclin-dependent kinase-like 5, SULFATE ION | Authors: | Richardson, W, Chen, X, Newman, J.A, Bakshi, S, Lakshminarayana, B, Brooke, L, Bullock, A.N. | Deposit date: | 2023-02-09 | Release date: | 2023-06-14 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Discovery of a Potent and Selective CDKL5/GSK3 Chemical Probe That Is Neuroprotective. Acs Chem Neurosci, 14, 2023
|
|
8ETN
| |
5O15
| Crystal structure of bifunctional dehydratase-cyclase domain in ambruticin biosynthesis | Descriptor: | AmbC, GLYCEROL | Authors: | Sung, K.H, Berkhan, G, Hollmann, T, Wagner, L, Hahn, F, Blankenfeldt, W. | Deposit date: | 2017-05-18 | Release date: | 2017-11-08 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.174 Å) | Cite: | Insights into the Dual Activity of a Bifunctional Dehydratase-Cyclase Domain. Angew. Chem. Int. Ed. Engl., 57, 2018
|
|
7W43
| |
6ERK
| Crystal structure of diaminopelargonic acid aminotransferase from Psychrobacter cryohalolentis | Descriptor: | 1,2-ETHANEDIOL, Aminotransferase, GLYCEROL, ... | Authors: | Boyko, K.M, Nikolaeva, A.Y, Bezsudnova, E.Y, Stekhanova, T.N, Rakitina, T.V, Popov, V.O. | Deposit date: | 2017-10-18 | Release date: | 2018-09-26 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Diaminopelargonic acid transaminase from Psychrobacter cryohalolentis is active towards (S)-(-)-1-phenylethylamine, aldehydes and alpha-diketones. Appl. Microbiol. Biotechnol., 102, 2018
|
|
6ETO
| Atomic resolution structure of RNase A (data collection 5) | Descriptor: | ISOPROPYL ALCOHOL, Ribonuclease pancreatic | Authors: | Caterino, M, Vergara, A, Merlino, A. | Deposit date: | 2017-10-27 | Release date: | 2018-02-21 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.02 Å) | Cite: | The Alkylquinolone Repertoire of Pseudomonas aeruginosa is Linked to Structural Flexibility of the FabH-like 2-Heptyl-3-hydroxy-4(1H)-quinolone (PQS) Biosynthesis Enzyme PqsBC. Chembiochem, 2018
|
|
7KL8
| Structure of F420 binding protein Rv1558 from Mycobacterium tuberculosis with F420 bound | Descriptor: | COENZYME F420, COENZYME F420-3, Deazaflavin-dependent nitroreductase, ... | Authors: | Lee, B.M, Tan, L.L, Jackson, C.J. | Deposit date: | 2020-10-29 | Release date: | 2021-03-24 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.469 Å) | Cite: | Potency boost of a Mycobacterium tuberculosis dihydrofolate reductase inhibitor by multienzyme F 420 H 2 -dependent reduction. Proc.Natl.Acad.Sci.USA, 118, 2021
|
|
6U1V
| Crystal structure of acyl-ACP/acyl-CoA dehydrogenase from allylmalonyl-CoA and FK506 biosynthesis, TcsD | Descriptor: | Acyl-CoA dehydrogenase domain-containing protein, DIHYDROFLAVINE-ADENINE DINUCLEOTIDE | Authors: | Blake-Hedges, J.M, Pereira, J.H, Barajas, J.F, Adams, P.D, Keasling, J.D. | Deposit date: | 2019-08-16 | Release date: | 2019-12-18 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structural Mechanism of Regioselectivity in an Unusual Bacterial Acyl-CoA Dehydrogenase. J.Am.Chem.Soc., 142, 2020
|
|