PDB: 66724 resultsInfo pagesStatus searchChemie searchBIRD

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6W43	APE1 AP-endonuclease product complex R237C Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... Authors: Freudenthal, B.D, Whitaker, A.M. Deposit date: 2020-03-10 Release date: 2020-06-10 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.99 Å) Cite: Molecular and structural characterization of disease-associated APE1 polymorphisms. DNA Repair (Amst.), 91-92, 2020
2V79	Crystal Structure of the N-terminal domain of DnaD from Bacillus Subtilis Descriptor: CHLORIDE ION, DNA REPLICATION PROTEIN DNAD, SODIUM ION Authors: Schneider, S, Zhang, W, Soultanas, P, Paoli, M. Deposit date: 2007-07-27 Release date: 2008-01-15 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2 Å) Cite: Structure of the N-Terminal Oligomerization Domain of Dnad Reveals a Unique Tetramerization Motif and Provides Insights Into Scaffold Formation. J.Mol.Biol., 376, 2008
8TFL	Ricin in complex with Fab SylH3 Descriptor: 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose, NONAETHYLENE GLYCOL, ... Authors: Rudolph, M.J, Mantis, N. Deposit date: 2023-07-11 Release date: 2024-04-17 Method: X-RAY DIFFRACTION (2.89 Å) Cite: Structural Basis of Antibody-Mediated Inhibition of Ricin Toxin Attachment to Host Cells. Biochemistry, 62, 2023
3LL9	X-ray structures of isopentenyl phosphate kinase Descriptor: ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, Isopentenyl phosphate kinase Authors: Hill, C.P, Schubert, H.L. Deposit date: 2010-01-28 Release date: 2010-06-02 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.148 Å) Cite: X-ray structures of isopentenyl phosphate kinase. Acs Chem.Biol., 5, 2010
8TFH	Ricin in complex with Fab JB4 Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, JB4 monoclonal antibody heavy chain, ... Authors: Rudolph, M.J, Mantis, N. Deposit date: 2023-07-11 Release date: 2024-04-17 Method: X-RAY DIFFRACTION (3.29 Å) Cite: Structural Basis of Antibody-Mediated Inhibition of Ricin Toxin Attachment to Host Cells. Biochemistry, 62, 2023
4G1P	Structural and Mechanistic Basis of Substrate Recognition by Novel Di-peptidase Dug1p From Saccharomyces cerevisiae Descriptor: CYSTEINE, Cys-Gly metallodipeptidase DUG1, GLYCINE, ... Authors: Singh, A.K, Singh, M, Pandya, V.K, Singh, V, Mittal, M, Kumaran, S. Deposit date: 2012-07-11 Release date: 2013-07-17 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.547 Å) Cite: Structural and Mechanistic Basis of Substrate Recognition by Novel Di-peptidase Dug1p From Saccromyces cerevesiae To be published
3L5W	Crystal structure of the complex between IL-13 and C836 FAB Descriptor: C836 HEAVY CHAIN, C836 LIGHT CHAIN, GLYCEROL, ... Authors: Teplyakov, A, Obmolova, G, Malia, T, Gilliland, G.L. Deposit date: 2009-12-22 Release date: 2010-04-14 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2 Å) Cite: Human framework adaptation of a mouse anti-human IL-13 antibody. J.Mol.Biol., 398, 2010
6W4I	APE1 Y269A product complex with abasic DNA Descriptor: DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*C)-3'), DNA (5'-D(P*(3DR)P*CP*GP*AP*CP*GP*GP*AP*TP*CP*C)-3'), DNA (5'-D(P*GP*GP*AP*TP*CP*CP*GP*TP*CP*GP*GP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), ... Authors: Freudenthal, B.D, Hoitsma, N.M. Deposit date: 2020-03-10 Release date: 2020-06-17 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.2 Å) Cite: AP-endonuclease 1 sculpts DNA through an anchoring tyrosine residue on the DNA intercalating loop. Nucleic Acids Res., 48, 2020
4E2F	Crystal Structure of E. coli Aspartate Transcarbamoylase K164E/E239K Mutant in an intermediate state Descriptor: Aspartate carbamoyltransferase catalytic chain, Aspartate carbamoyltransferase regulatory chain, ZINC ION Authors: Guo, W, Kantrowitz, E.R. Deposit date: 2012-03-08 Release date: 2012-05-02 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Trapping and structure determination of an intermediate in the allosteric transition of aspartate transcarbamoylase. Proc.Natl.Acad.Sci.USA, 109, 2012
3LHP	Crystal structure of HIV epitope-scaffold 4E10_D0_1ISEA_004_N 4E10 Fv complex Descriptor: 1,2-ETHANEDIOL, 4E10_D0_1ISEA_004_N (T93), Fv 4E10 heavy chain, ... Authors: Holmes, M.A. Deposit date: 2010-01-22 Release date: 2010-09-22 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Computational Design of Epitope-Scaffolds Allows Induction of Antibodies Specific for a Poorly Immunogenic HIV Vaccine Epitope. Structure, 18, 2010
4DY9	Leishmania major Peroxidase is a Cytochrome c Peroxidase Descriptor: Cytochrome c, PROTOPORPHYRIN IX CONTAINING FE Authors: Jasion, V.S, Poulos, T.L. Deposit date: 2012-02-28 Release date: 2012-03-14 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.082 Å) Cite: Leishmania major Peroxidase Is a Cytochrome c Peroxidase. Biochemistry, 51, 2012
4GIG	crystal structure of T69A mutant of trapped Dnae intein precursor Descriptor: DNA polymerase III subunit alpha, SULFATE ION Authors: Van Roey, P. Deposit date: 2012-08-08 Release date: 2013-03-06 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.8 Å) Cite: A conserved threonine spring-loads precursor for intein splicing. Protein Sci., 22, 2013
3L7E	Crystal structure of ANTI-IL-13 antibody C836 Descriptor: ACETATE ION, C836 HEAVY CHAIN, C836 LIGHT CHAIN, ... Authors: Teplyakov, A, Obmolova, G, Malia, T, Gilliland, G.L. Deposit date: 2009-12-28 Release date: 2010-11-10 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Antigen recognition by antibody C836 through adjustment of VL/VH packing Acta Crystallogr.,Sect.F, 67, 2011
2J2I	Crystal Structure of the humab PIM1 in complex with LY333531 Descriptor: (9R)-9-[(DIMETHYLAMINO)METHYL]-6,7,10,11-TETRAHYDRO-9H,18H-5,21:12,17-DIMETHENODIBENZO[E,K]PYRROLO[3,4-H][1,4,13]OXADIA ZACYCLOHEXADECINE-18,20-DIONE, PROTO-ONCOGENE SERINE/THREONINE-PROTEIN KINASE PIM-1, SULFATE ION Authors: Debreczeni, J.E, Bullock, A.N, von Delft, F, Sundstrom, M, Arrowsmith, C, Edwards, A, Weigelt, J, Knapp, S. Deposit date: 2006-08-16 Release date: 2007-02-13 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (1.9 Å) Cite: A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases. Proc. Natl. Acad. Sci. U.S.A., 104, 2007
3LQU	Crystal structure of 3,4-Dihydroxy-2-butanone 4-phosphate synthase complexed with Ribulose-5 phosphate Descriptor: 3,4-dihydroxy-2-butanone 4-phosphate synthase, 5-O-phosphono-D-xylulose Authors: Kumar, P, Karthikeyan, S. Deposit date: 2010-02-10 Release date: 2010-09-15 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.522 Å) Cite: Potential anti-bacterial drug target: structural characterization of 3,4-dihydroxy-2-butanone-4-phosphate synthase from Salmonella typhimurium LT2. Proteins, 78, 2010
2VOE	Crystal structure of Rv2780 from M. tuberculosis H37Rv Descriptor: ALANINE DEHYDROGENASE Authors: Tripathi, S.M, Ramachandran, R. Deposit date: 2008-02-17 Release date: 2008-03-04 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Crystal Structures of the Mycobacterium Tuberculosis Secretory Antigen Alanine Dehydrogenase (Rv2780) in Apo and Ternary Complex Forms Captures "Open" and "Closed" Enzyme Conformations. Proteins, 72, 2008
3L7F	Structure of IL-13 antibody H2L6, A humanized variant OF C836 Descriptor: CALCIUM ION, H2L6 HEAVY CHAIN, H2L6 LIGHT CHAIN, ... Authors: Teplyakov, A, Obmolova, G, Malia, T, Gilliland, G.L. Deposit date: 2009-12-28 Release date: 2010-11-10 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Human framework adaptation of a mouse anti-human IL-13 antibody. J.Mol.Biol., 398, 2010
3LH2	Crystal structure of HIV epitope-scaffold 4E10_1VI7A_S0_002_N 4E10 Fv complex Descriptor: 4E10_1VI7A_S0_002_N (T88), Fv 4E10 heavy chain, Fv 4E10 light chain Authors: Holmes, M.A. Deposit date: 2010-01-21 Release date: 2010-09-22 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.65 Å) Cite: Computational Design of Epitope-Scaffolds Allows Induction of Antibodies Specific for a Poorly Immunogenic HIV Vaccine Epitope. Structure, 18, 2010
6VX2	HIV Integrase core domain in complex with inhibitor (5-methyl-1-benzofuran-3-yl)acetic acid Descriptor: (5-methyl-1-benzofuran-3-yl)acetic acid, IODIDE ION, Integrase, ... Authors: Gorman, M.A, Parker, M.W. Deposit date: 2020-02-21 Release date: 2021-02-24 Method: X-RAY DIFFRACTION (2.4 Å) Cite: HIV Integrase core domain in complex with inhibitor (5-methyl-1-benzofuran-3-yl)acetic acid To Be Published
3LUG	Crystal structure of MID domain from hAGO2 in complex with CMP Descriptor: CYTIDINE-5'-MONOPHOSPHATE, PHOSPHATE ION, Protein argonaute-2 Authors: Frank, F, Sonenberg, N, Nagar, B. Deposit date: 2010-02-17 Release date: 2010-05-26 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.849 Å) Cite: Structural basis for 5'-nucleotide base-specific recognition of guide RNA by human AGO2. Nature, 465, 2010
6W0U	HIV Integrase core domain in complex with inhibitor 2-(2-ethynyl-5-methyl-1-benzofuran-3-yl)acetic acid Descriptor: 2-(2-ethynyl-5-methyl-1-benzofuran-3-yl)ethanoic acid, IODIDE ION, Integrase, ... Authors: Gorman, M.A, Parker, M.W. Deposit date: 2020-03-02 Release date: 2021-03-03 Method: X-RAY DIFFRACTION (2.19 Å) Cite: HIV Integrase core domain in complex with inhibitor To Be Published
8T52	HIV-1 Integrase Catalytic Core Domain (CCD) F185H/Y99H/A128T Mutant Complexed with EKC-110 Descriptor: (2S)-tert-butoxy{4-(4-chlorophenyl)-2,6-dimethyl-1-[(1-methyl-1H-pyrazol-4-yl)methyl]-1H-pyrrolo[2,3-b]pyridin-5-yl}acetic acid, Integrase Authors: Dinh, T, Kvaratskhelia, M. Deposit date: 2023-06-12 Release date: 2024-06-19 Last modified: 2024-07-31 Method: X-RAY DIFFRACTION (2.07 Å) Cite: The structural and mechanistic bases for the viral resistance to allosteric HIV-1 integrase inhibitor pirmitegravir. Biorxiv, 2024
6W42	HIV Integrase core domain in complex with inhibitor 2-(5-methyl-2-(2-(thiophen-2-yl)ethynyl)-1-benzofuran-3-yl)acetic acid Descriptor: 2-[5-methyl-2-(2-thiophen-2-ylethynyl)-1-benzofuran-3-yl]ethanoic acid, HIV Integrase catalytic domain, IODIDE ION, ... Authors: Gorman, M.A, Parker, M.W. Deposit date: 2020-03-09 Release date: 2021-03-10 Method: X-RAY DIFFRACTION (2.26 Å) Cite: HIV Integrase core domain in complex with inhibitor (5-methyl-1-benzofuran-3-yl)acetic acid To Be Published
6W11	The structure of Sulfolobus solfataricus Csa3 in complex with cyclic tetraadenylate (cA4) Descriptor: CRISPR locus-related putative DNA-binding protein Csa3, cA4 Authors: Charbonneau, A.A, Gauvin, C.C, Lawrence, C.M. Deposit date: 2020-03-03 Release date: 2021-03-10 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.46 Å) Cite: Cyclic Tetra-Adenylate (cA 4 ) Recognition by Csa3; Implications for an Integrated Class 1 CRISPR-Cas Immune Response in Saccharolobus solfataricus. Biomolecules, 11, 2021
6W6T	WT HIV-1 Protease in Complex with Phosphonated UMass6 (PU6) Descriptor: Protease, SULFATE ION, diethyl [(4-{(2S,3R)-4-{[(4-aminophenyl)sulfonyl](2-ethylbutyl)amino}-2-[({[(3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl]oxy}carbonyl)amino]-3-hydroxybutyl}phenoxy)methyl]phosphonate Authors: Lockbaum, G.J, Henes, M, Kosovrasti, K, Nalivaika, E.A, Ali, A, KurtYilmaz, N, Schiffer, C.A. Deposit date: 2020-03-17 Release date: 2021-03-17 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.84 Å) Cite: To Be Determined To Be Published

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