4JAQ
| Crystal Structure of Mycobacterium tuberculosis PKS11 Reveals Intermediates in the Synthesis of Methyl-branched Alkylpyrones | Descriptor: | 3,5-dioxoicosanoic acid, Alpha-pyrone synthesis polyketide synthase-like Pks11, COENZYME A, ... | Authors: | Gokulan, K, Sacchettini, J.C, Mycobacterium Tuberculosis Structural Proteomics Project (XMTB) | Deposit date: | 2013-02-19 | Release date: | 2013-04-24 | Last modified: | 2013-11-27 | Method: | X-RAY DIFFRACTION (1.73 Å) | Cite: | Crystal structure of Mycobacterium tuberculosis polyketide synthase 11 (PKS11) reveals intermediates in the synthesis of methyl-branched alkylpyrones. J.Biol.Chem., 288, 2013
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4JD3
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4JAR
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4JAP
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4JAO
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4JAT
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2ZW7
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5ONC
| Catabolism of the Cholesterol Side Chain in Mycobacterium tuberculosis is Controlled by a Redox-Sensitive Thiol Switch | Descriptor: | CHLORIDE ION, Steroid 3-ketoacyl-CoA thiolase | Authors: | Schaefer, C, Kuper, J, Sampson, N.S, Kisker, C. | Deposit date: | 2017-08-03 | Release date: | 2017-08-23 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.19 Å) | Cite: | Catabolism of the Cholesterol Side Chain in Mycobacterium tuberculosis Is Controlled by a Redox-Sensitive Thiol Switch. ACS Infect Dis, 3, 2017
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3UNO
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5ZQN
| Crystal structure of Mycobacterium tuberculosis HisB in complex with a ligand | Descriptor: | (2R,3S)-2,3-dihydroxy-3-(1H-imidazol-5-yl)propyl dihydrogen phosphate, CHLORIDE ION, Imidazoleglycerol-phosphate dehydratase, ... | Authors: | Kumar, D, Pal, R.K, Biswal, B.K. | Deposit date: | 2018-04-19 | Release date: | 2018-05-16 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Characterization of a triazole scaffold compound as an inhibitor of Mycobacterium tuberculosis imidazoleglycerol-phosphate dehydratase. Proteins, 2021
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7U22
| Mycobacterium tuberculosis RNA polymerase sigma A holoenzyme open promoter complex containing UMN-7 | Descriptor: | (9S,14S,15R,16S,17R,18R,19R,20S,21S,25R)-5,6,18,20-tetrahydroxy-14-methoxy-7,9,15,17,19,21,25-heptamethyl-1'-(2-methylpropyl)-10,26-dioxo-1,3,9,10-tetrahydrospiro[9,4-(epoxypentadecanoimino)furo[2',3':7,8]naphtho[1,2-d]imidazole-2,4'-piperidin]-16-yl benzoate, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | Authors: | Molodtsov, V, Ebright, R.H. | Deposit date: | 2022-02-22 | Release date: | 2022-10-19 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.87 Å) | Cite: | Redesign of Rifamycin Antibiotics to Overcome ADP-Ribosylation-Mediated Resistance. Angew.Chem.Int.Ed.Engl., 61, 2022
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7CS1
| Aminoglycoside 2'-N-acetyltransferase from Mycolicibacterium smegmatis-Complex with Coenzyme A and Neomycin | Descriptor: | Aminoglycoside 2'-N-acetyltransferase, COENZYME A, NEOMYCIN | Authors: | Jeong, C.S, Hwang, J, Do, H, Lee, J.H. | Deposit date: | 2020-08-14 | Release date: | 2021-06-23 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.966 Å) | Cite: | Structural and biochemical analyses of an aminoglycoside 2'-N-acetyltransferase from Mycolicibacterium smegmatis. Sci Rep, 10, 2020
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7CS0
| Aminoglycoside 2'-N-acetyltransferase from Mycolicibacterium smegmatis-Complex with Coenzyme A and Paromomycin | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, Aminoglycoside 2'-N-acetyltransferase, ... | Authors: | Jeong, C.S, Hwang, J, Do, H, Lee, J.H. | Deposit date: | 2020-08-14 | Release date: | 2021-06-23 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Structural and biochemical analyses of an aminoglycoside 2'-N-acetyltransferase from Mycolicibacterium smegmatis. Sci Rep, 10, 2020
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8HKR
| Crystal Structure of Histone H3 Lysine 79 (H3K79) Methyltransferase Rv2067c from Mycobacterium tuberculosis | Descriptor: | PHOSPHATE ION, Protein lysine methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE | Authors: | Dadireddy, V, Singh, P.R, Kalladi, S.M, Valakunja, N, Ramakumar, S. | Deposit date: | 2022-11-28 | Release date: | 2023-10-18 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | The Mycobacterium tuberculosis methyltransferase Rv2067c manipulates host epigenetic programming to promote its own survival. Nat Commun, 14, 2023
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7NJK
| Mycobacterium smegmatis ATP synthase state 1a | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase epsilon chain, ... | Authors: | Montgomery, M.G, Petri, J, Spikes, T.E, Walker, J.E. | Deposit date: | 2021-02-17 | Release date: | 2021-10-27 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (2.52 Å) | Cite: | Structure of the ATP synthase from Mycobacterium smegmatis provides targets for treating tuberculosis. Proc.Natl.Acad.Sci.USA, 118, 2021
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7NJR
| Mycobacterium smegmatis ATP synthase state 3b | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase epsilon chain, ... | Authors: | Montgomery, M.G, Petri, J, Spikes, T.E, Walker, J.E. | Deposit date: | 2021-02-17 | Release date: | 2021-10-27 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (2.56 Å) | Cite: | Structure of the ATP synthase from Mycobacterium smegmatis provides targets for treating tuberculosis. Proc.Natl.Acad.Sci.USA, 118, 2021
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7NJM
| Mycobacterium smegmatis ATP synthase state 1c | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase epsilon chain, ... | Authors: | Montgomery, M.G, Petri, J, Spikes, T.E, Walker, J.E. | Deposit date: | 2021-02-17 | Release date: | 2021-10-27 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (2.84 Å) | Cite: | Structure of the ATP synthase from Mycobacterium smegmatis provides targets for treating tuberculosis. Proc.Natl.Acad.Sci.USA, 118, 2021
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7NJS
| Mycobacterium smegmatis ATP synthase state 3c | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase epsilon chain, ... | Authors: | Montgomery, M.G, Petri, J, Spikes, T.E, Walker, J.E. | Deposit date: | 2021-02-17 | Release date: | 2021-10-27 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (2.46 Å) | Cite: | Structure of the ATP synthase from Mycobacterium smegmatis provides targets for treating tuberculosis. Proc.Natl.Acad.Sci.USA, 118, 2021
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7NJQ
| Mycobacterium smegmatis ATP synthase state 3a | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase epsilon chain, ... | Authors: | Montgomery, M.G, Petri, J, Spikes, T.E, Walker, J.E. | Deposit date: | 2021-02-17 | Release date: | 2021-10-27 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (2.67 Å) | Cite: | Structure of the ATP synthase from Mycobacterium smegmatis provides targets for treating tuberculosis. Proc.Natl.Acad.Sci.USA, 118, 2021
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7NJP
| Mycobacterium smegmatis ATP synthase state 2 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase epsilon chain, ... | Authors: | Montgomery, M.G, Petri, J, Spikes, T.E, Walker, J.E. | Deposit date: | 2021-02-17 | Release date: | 2021-10-27 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (2.84 Å) | Cite: | Structure of the ATP synthase from Mycobacterium smegmatis provides targets for treating tuberculosis. Proc.Natl.Acad.Sci.USA, 118, 2021
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7NJO
| Mycobacterium smegmatis ATP synthase state 1e | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase epsilon chain, ... | Authors: | Montgomery, M.G, Petri, J, Spikes, T.E, Walker, J.E. | Deposit date: | 2021-02-17 | Release date: | 2021-10-27 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (2.92 Å) | Cite: | Structure of the ATP synthase from Mycobacterium smegmatis provides targets for treating tuberculosis. Proc.Natl.Acad.Sci.USA, 118, 2021
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7NJL
| Mycobacterium smegmatis ATP synthase state 1b | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase epsilon chain, ... | Authors: | Montgomery, M.G, Petri, J, Spikes, T.E, Walker, J.E. | Deposit date: | 2021-02-17 | Release date: | 2021-10-27 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (2.71 Å) | Cite: | Structure of the ATP synthase from Mycobacterium smegmatis provides targets for treating tuberculosis. Proc.Natl.Acad.Sci.USA, 118, 2021
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7NL9
| Mycobacterium smegmatis ATP synthase Fo state 3 | Descriptor: | ATP synthase epsilon chain, ATP synthase gamma chain, ATP synthase subunit a, ... | Authors: | Montgomery, M.G, Petri, J, Spikes, T.E, Walker, J.E. | Deposit date: | 2021-02-22 | Release date: | 2021-10-27 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (2.86 Å) | Cite: | Structure of the ATP synthase from Mycobacterium smegmatis provides targets for treating tuberculosis. Proc.Natl.Acad.Sci.USA, 118, 2021
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7NJN
| Mycobacterium smegmatis ATP synthase state 1d | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase epsilon chain, ... | Authors: | Montgomery, M.G, Petri, J, Spikes, T.E, Walker, J.E. | Deposit date: | 2021-02-17 | Release date: | 2021-10-27 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (2.64 Å) | Cite: | Structure of the ATP synthase from Mycobacterium smegmatis provides targets for treating tuberculosis. Proc.Natl.Acad.Sci.USA, 118, 2021
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7NKP
| Mycobacterium smegmatis ATP synthase Fo state 2 | Descriptor: | ATP synthase epsilon chain, ATP synthase gamma chain, ATP synthase subunit a, ... | Authors: | Montgomery, M.G, Petri, J, Spikes, T.E, Walker, J.E. | Deposit date: | 2021-02-18 | Release date: | 2021-10-27 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (4.06 Å) | Cite: | Structure of the ATP synthase from Mycobacterium smegmatis provides targets for treating tuberculosis. Proc.Natl.Acad.Sci.USA, 118, 2021
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