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6IR9
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BU of 6ir9 by Molmil
RNA polymerase II elongation complex bound with Elf1 and Spt4/5, stalled at SHL(-1) of the nucleosome
Descriptor: DNA (198-MER), DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ...
Authors:Ehara, H, Kujirai, T, Fujino, Y, Shirouzu, M, Kurumizaka, H, Sekine, S.
Deposit date:2018-11-12
Release date:2019-02-20
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structural insight into nucleosome transcription by RNA polymerase II with elongation factors.
Science, 363, 2019
6INQ
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BU of 6inq by Molmil
RNA polymerase II elongation complex stalled at SHL(-1) of the nucleosome, with foreign DNA (+1 position)
Descriptor: DNA (198-MER), DNA (31-MER), DNA-directed RNA polymerase subunit, ...
Authors:Kujirai, T, Ehara, H, Fujino, Y, Shirouzu, M, Sekine, S, Kurumizaka, H.
Deposit date:2018-10-26
Release date:2019-04-03
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (6.9 Å)
Cite:Structural basis of the nucleosome transition during RNA polymerase II passage.
Science, 362, 2018
8JH4
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BU of 8jh4 by Molmil
RNA polymerase II elongation complex containing 60 bp upstream DNA loop, stalled at SHL(-1) of the nucleosome
Descriptor: DNA (198-MER), DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ...
Authors:Akatsu, M, Fujita, R, Ogasawara, M, Ehara, H, Kujirai, T, Takizawa, Y, Sekine, S, Kurumizaka, H.
Deposit date:2023-05-22
Release date:2023-11-29
Last modified:2023-12-20
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Cryo-EM structures of RNA polymerase II-nucleosome complexes rewrapping transcribed DNA.
J.Biol.Chem., 299, 2023
8JH2
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BU of 8jh2 by Molmil
RNA polymerase II elongation complex bound with Elf1, Spt4/5 and foreign DNA, stalled at SHL(-1) of the nucleosome
Descriptor: DNA (218-MER), DNA (40-MER), DNA-directed RNA polymerase subunit, ...
Authors:Akatsu, M, Fujita, R, Ogasawara, M, Ehara, H, Kujirai, T, Takizawa, Y, Sekine, S, Kurumizaka, H.
Deposit date:2023-05-22
Release date:2023-11-29
Last modified:2023-12-20
Method:ELECTRON MICROSCOPY (5.7 Å)
Cite:Cryo-EM structures of RNA polymerase II-nucleosome complexes rewrapping transcribed DNA.
J.Biol.Chem., 299, 2023
8JH3
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BU of 8jh3 by Molmil
RNA polymerase II elongation complex containing 40 bp upstream DNA loop, stalled at SHL(-1) of the nucleosome
Descriptor: DNA (198-MER), DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ...
Authors:Akatsu, M, Fujita, R, Ogasawara, M, Ehara, H, Kujirai, T, Takizawa, Y, Sekine, S, Kurumizaka, H.
Deposit date:2023-05-22
Release date:2023-11-29
Last modified:2023-12-20
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Cryo-EM structures of RNA polymerase II-nucleosome complexes rewrapping transcribed DNA.
J.Biol.Chem., 299, 2023
5JA4
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BU of 5ja4 by Molmil
Crystal structure of human TONSL and MCM2 HBDs binding to a histone H3-H4 tetramer
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DNA replication licensing factor MCM2, GLYCEROL, ...
Authors:Huang, H, Patel, D.
Deposit date:2016-04-11
Release date:2016-06-15
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.424 Å)
Cite:H4K20me0 marks post-replicative chromatin and recruits the TONSL-MMS22L DNA repair complex.
Nature, 534, 2016
4GNE
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BU of 4gne by Molmil
Crystal Structure of NSD3 tandem PHD5-C5HCH domains complexed with H3 peptide 1-7
Descriptor: Histone H3.3, Histone-lysine N-methyltransferase NSD3, ZINC ION
Authors:Li, F, He, C, Wu, J, Shi, Y.
Deposit date:2012-08-17
Release date:2013-01-02
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.47 Å)
Cite:The methyltransferase NSD3 has chromatin-binding motifs, PHD5-C5HCH, that are distinct from other NSD (nuclear receptor SET domain) family members in their histone H3 recognition.
J.Biol.Chem., 288, 2013
4GNF
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BU of 4gnf by Molmil
Crystal Structure of NSD3 tandem PHD5-C5HCH domains complexed with H3 peptide 1-15
Descriptor: Histone H3.3, Histone-lysine N-methyltransferase NSD3, ZINC ION
Authors:Li, F, He, C, Wu, J, Shi, Y.
Deposit date:2012-08-17
Release date:2013-01-02
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:The methyltransferase NSD3 has chromatin-binding motifs, PHD5-C5HCH, that are distinct from other NSD (nuclear receptor SET domain) family members in their histone H3 recognition.
J.Biol.Chem., 288, 2013
3MUL
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BU of 3mul by Molmil
Crystal structure of Brd4 bromodomain 1 with butyrylated histone H3-K(buty)14
Descriptor: 1,2-ETHANEDIOL, Bromodomain-containing protein 4, Peptide of Histone H3.3
Authors:Vollmuth, F, Geyer, M.
Deposit date:2010-05-03
Release date:2010-08-11
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Interaction of propionylated and butyrylated histone H3 lysine marks with Brd4 bromodomains
Angew.Chem.Int.Ed.Engl., 49, 2010
3MUK
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BU of 3muk by Molmil
Crystal structure of Brd4 bromodomain 1 with propionylated histone H3-K(prop)23
Descriptor: 1,2-ETHANEDIOL, Bromodomain-containing protein 4, peptide of Histone H3.3
Authors:Vollmuth, F, Geyer, M.
Deposit date:2010-05-03
Release date:2010-08-11
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Interaction of propionylated and butyrylated histone H3 lysine marks with Brd4 bromodomains
Angew.Chem.Int.Ed.Engl., 49, 2010
6A5L
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BU of 6a5l by Molmil
RNA polymerase II elongation complex stalled at SHL(-1) of the nucleosome, with foreign DNA
Descriptor: DNA (198-MER), DNA (42-MER), DNA-directed RNA polymerase subunit, ...
Authors:Kujirai, T, Ehara, H, Fujino, Y, Shirouzu, M, Sekine, S, Kurumizaka, H.
Deposit date:2018-06-24
Release date:2018-10-03
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (5.6 Å)
Cite:Structural basis of the nucleosome transition during RNA polymerase II passage.
Science, 362, 2018
6A5R
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BU of 6a5r by Molmil
RNA polymerase II elongation complex stalled at SHL(-2) of the nucleosome
Descriptor: DNA (198-MER), DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ...
Authors:Kujirai, T, Ehara, H, Fujino, Y, Shirouzu, M, Sekine, S, Kurumizaka, H.
Deposit date:2018-06-25
Release date:2018-10-03
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (8.7 Å)
Cite:Structural basis of the nucleosome transition during RNA polymerase II passage.
Science, 362, 2018
6A5O
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BU of 6a5o by Molmil
RNA polymerase II elongation complex stalled at SHL(-6) of the nucleosome
Descriptor: DNA (198-MER), DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ...
Authors:Kujirai, T, Ehara, H, Fujino, Y, Shirouzu, M, Sekine, S, Kurumizaka, H.
Deposit date:2018-06-25
Release date:2018-10-03
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (9.9 Å)
Cite:Structural basis of the nucleosome transition during RNA polymerase II passage.
Science, 362, 2018
6A5T
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BU of 6a5t by Molmil
RNA polymerase II elongation complex stalled at SHL(-1) of the nucleosome
Descriptor: DNA (198-MER), DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ...
Authors:Kujirai, T, Ehara, H, Fujino, Y, Shirouzu, M, Sekine, S, Kurumizaka, H.
Deposit date:2018-06-25
Release date:2018-10-03
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (6.7 Å)
Cite:Structural basis of the nucleosome transition during RNA polymerase II passage.
Science, 362, 2018
6A5U
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BU of 6a5u by Molmil
RNA polymerase II elongation complex stalled at SHL(-1) of the nucleosome, with foreign DNA, tilt conformation
Descriptor: DNA (198-MER), DNA (40-MER), DNA-directed RNA polymerase subunit, ...
Authors:Kujirai, T, Ehara, H, Fujino, Y, Shirouzu, M, Sekine, S, Kurumizaka, H.
Deposit date:2018-06-25
Release date:2018-10-03
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (7.6 Å)
Cite:Structural basis of the nucleosome transition during RNA polymerase II passage.
Science, 362, 2018
6A5P
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BU of 6a5p by Molmil
RNA polymerase II elongation complex stalled at SHL(-5) of the nucleosome
Descriptor: DNA (198-MER), DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ...
Authors:Kujirai, T, Ehara, H, Fujino, Y, Shirouzu, M, Sekine, S, Kurumizaka, H.
Deposit date:2018-06-25
Release date:2018-10-03
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (7 Å)
Cite:Structural basis of the nucleosome transition during RNA polymerase II passage.
Science, 362, 2018
3QL9
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BU of 3ql9 by Molmil
Monoclinic complex structure of ATRX ADD bound to histone H3K9me3 peptide
Descriptor: Transcriptional regulator ATRX, ZINC ION, peptide of Histone H3.3
Authors:Xiang, B, Li, H.
Deposit date:2011-02-02
Release date:2011-06-15
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (0.93 Å)
Cite:ATRX ADD domain links an atypical histone methylation recognition mechanism to human mental-retardation syndrome
Nat.Struct.Mol.Biol., 18, 2011
7V1M
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BU of 7v1m by Molmil
Structural basis for the co-chaperone relationship of sNASP and ASF1b
Descriptor: Histone H3.3, Histone H4, Histone chaperone ASF1B, ...
Authors:Bao, H, Huang, H.
Deposit date:2021-08-04
Release date:2022-04-20
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.834 Å)
Cite:NASP maintains histone H3-H4 homeostasis through two distinct H3 binding modes.
Nucleic Acids Res., 50, 2022
7WBV
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BU of 7wbv by Molmil
RNA polymerase II elongation complex bound with Elf1 and Spt4/5, stalled at SHL(-4) of the nucleosome
Descriptor: DNA (159-MER), DNA (198-MER), DNA-directed RNA polymerase subunit, ...
Authors:Osumi, K, Kujirai, T, Ehara, H, Sekine, S, Takizawa, Y, Kurumizaka, H.
Deposit date:2021-12-17
Release date:2023-07-05
Last modified:2024-06-26
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Structural Basis of Damaged Nucleotide Recognition by Transcribing RNA Polymerase II in the Nucleosome.
J.Mol.Biol., 435, 2023
7WBX
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BU of 7wbx by Molmil
RNA polymerase II elongation complex bound with Elf1 and Spt4/5, stalled at SHL(-3) of the nucleosome
Descriptor: DNA (198-MER), DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ...
Authors:Osumi, K, Kujirai, T, Ehara, H, Sekine, S, Takizawa, Y, Kurumizaka, H.
Deposit date:2021-12-17
Release date:2023-07-05
Last modified:2024-06-26
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structural Basis of Damaged Nucleotide Recognition by Transcribing RNA Polymerase II in the Nucleosome.
J.Mol.Biol., 435, 2023
7WBW
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BU of 7wbw by Molmil
RNA polymerase II elongation complex bound with Elf1 and Spt4/5, stalled at SHL(-3.5) of the nucleosome
Descriptor: DNA (198-MER), DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ...
Authors:Osumi, K, Kujirai, T, Ehara, H, Sekine, S, Takizawa, Y, Kurumizaka, H.
Deposit date:2021-12-17
Release date:2023-07-05
Last modified:2024-06-26
Method:ELECTRON MICROSCOPY (7.1 Å)
Cite:Structural Basis of Damaged Nucleotide Recognition by Transcribing RNA Polymerase II in the Nucleosome.
J.Mol.Biol., 435, 2023
3QLC
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BU of 3qlc by Molmil
Complex structure of ATRX ADD domain bound to unmodified H3 1-15 peptide
Descriptor: Transcriptional regulator ATRX, ZINC ION, peptide of Histone H3.3
Authors:Li, H, Patel, D.J.
Deposit date:2011-02-02
Release date:2011-06-15
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:ATRX ADD domain links an atypical histone methylation recognition mechanism to human mental-retardation syndrome
Nat.Struct.Mol.Biol., 18, 2011
3QLA
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BU of 3qla by Molmil
Hexagonal complex structure of ATRX ADD bound to H3K9me3 peptide
Descriptor: POTASSIUM ION, Transcriptional regulator ATRX, ZINC ION, ...
Authors:Xiang, B, Li, H.
Deposit date:2011-02-02
Release date:2011-06-15
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:ATRX ADD domain links an atypical histone methylation recognition mechanism to human mental-retardation syndrome
Nat.Struct.Mol.Biol., 18, 2011
7XSE
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BU of 7xse by Molmil
RNA polymerase II elongation complex transcribing a nucleosome (EC42)
Descriptor: Component of the Paf1p complex, Constituent of Paf1 complex with RNA polymerase II, Paf1p, ...
Authors:Ehara, H, Kujirai, T, Shirouzu, M, Kurumizaka, H, Sekine, S.
Deposit date:2022-05-13
Release date:2022-09-07
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structural basis of nucleosome disassembly and reassembly by RNAPII elongation complex with FACT.
Science, 377, 2022
7XSX
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BU of 7xsx by Molmil
RNA polymerase II elongation complex transcribing a nucleosome (EC49)
Descriptor: Component of the Paf1p complex, Constituent of Paf1 complex with RNA polymerase II, Paf1p, ...
Authors:Ehara, H, Kujirai, T, Shirouzu, M, Kurumizaka, H, Sekine, S.
Deposit date:2022-05-15
Release date:2022-09-07
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structural basis of nucleosome disassembly and reassembly by RNAPII elongation complex with FACT.
Science, 377, 2022

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