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6BSC
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BU of 6bsc by Molmil
Crystal structure of the Mucin-1 SEA domain
Descriptor: Mucin-1
Authors:Noguera, M.E, Jakoncic, J, Ermacora, M.R.
Deposit date:2017-12-01
Release date:2018-12-05
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.303 Å)
Cite:High-resolution structure of intramolecularly proteolyzed human mucin-1 SEA domain.
Biochim Biophys Acta Proteins Proteom, 1868, 2020
5LR8
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BU of 5lr8 by Molmil
Structure of plastidial phosphorylase Pho1 from Barley
Descriptor: Alpha-1,4 glucan phosphorylase, CITRIC ACID, PYRIDOXAL-5'-PHOSPHATE
Authors:Cuesta-Seijo, J.A, Ruzanski, C, Kruzewicz, K, Palcic, M.M.
Deposit date:2016-08-18
Release date:2017-05-03
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Functional and structural characterization of plastidic starch phosphorylase during barley endosperm development.
PLoS ONE, 12, 2017
4K1T
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BU of 4k1t by Molmil
Gly-Ser-SplB protease from Staphylococcus aureus at 1.60 A resolution
Descriptor: CHLORIDE ION, SULFATE ION, Serine protease SplB, ...
Authors:Zdzalik, M, Pustelny, K, Stec-Niemczyk, J, Cichon, P, Czarna, A, Popowicz, G, Drag, M, Wladyka, B, Potempa, J, Dubin, A, Dubin, G.
Deposit date:2013-04-05
Release date:2014-04-16
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Staphylococcal SplB Serine Protease Utilizes a Novel Molecular Mechanism of Activation.
J.Biol.Chem., 289, 2014
3ZGG
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BU of 3zgg by Molmil
Crystal structure of the Fucosylgalactoside alpha N- acetylgalactosaminyltransferase (GTA, cisAB mutant L266G, G268A) in complex with NPE caged UDP-Gal (C222(1) space group)
Descriptor: 1-(2-NITROPHENYL)ETHYL UDP-GALACTOSE, GLYCEROL, HISTO-BLOOD GROUP ABO SYSTEM TRANSFERASE, ...
Authors:Jorgensen, R, Batot, G.O, Hindsgaul, O, Tanaka, H, Perez, S, Imberty, A, Breton, C, Royant, A, Palcic, M.M.
Deposit date:2012-12-17
Release date:2014-01-15
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structures of a Human Blood Group Glycosyltransferase in Complex with a Photo-Activatable Udp-Gal Derivative Reveal Two Different Binding Conformations
Acta Crystallogr.,Sect.F, 70, 2014
4GRY
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BU of 4gry by Molmil
Crystal structure of SHP1 catalytic domain with SO4
Descriptor: SULFATE ION, Tyrosine-protein phosphatase non-receptor type 6
Authors:Alicea-Velazquez, N.L, Jakoncic, J, Boggon, T.J.
Deposit date:2012-08-27
Release date:2012-12-19
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.6998 Å)
Cite:Structure-guided studies of the SHP-1/JAK1 interaction provide new insights into phosphatase catalytic domain substrate recognition.
J.Struct.Biol., 181, 2013
1ZJ1
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BU of 1zj1 by Molmil
Crystal Structure of Human Galactosyltransferase (GTB) Complexed with N-acetyllactosamine
Descriptor: ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase), ...
Authors:Letts, J.A, Rose, N.L, Fang, Y.R, Barry, C.H, Borisova, S.N, Seto, N.O, Palcic, M.M, Evans, S.V.
Deposit date:2005-04-27
Release date:2005-12-13
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Differential Recognition of the Type I and II H Antigen Acceptors by the Human ABO(H) Blood Group A and B Glycosyltransferases.
J.Biol.Chem., 281, 2006
1ZJO
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BU of 1zjo by Molmil
Crystal Structure of Human N-acetylgalactosaminyltransferase (GTA) Complexed with Galactose-grease
Descriptor: CHLORIDE ION, Histo-blood group ABO system transferase (NAGAT) Includes: Glycoprotein-fucosylgalactoside alpha-N- acetylgalactosaminyltransferase, MANGANESE (II) ION, ...
Authors:Letts, J.A, Rose, N.L, Fang, Y.R, Barry, C.H, Borisova, S.N, Seto, N.O, Palcic, M.M, Evans, S.V.
Deposit date:2005-04-29
Release date:2005-12-13
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:Differential Recognition of the Type I and II H Antigen Acceptors by the Human ABO(H) Blood Group A and B Glycosyltransferases.
J.Biol.Chem., 281, 2006
8ONT
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BU of 8ont by Molmil
Structure of Setaria italica NRAT in complex with a nanobody
Descriptor: DIUNDECYL PHOSPHATIDYL CHOLINE, NRAMP related aluminium transporter, Nanobody1
Authors:Ramanadane, K, Liziczai, M, Markovic, D, Straub, M.S, Rosalen, G.T, Udovcic, A, Dutzler, R, Manatschal, C.
Deposit date:2023-04-03
Release date:2023-04-12
Last modified:2023-10-25
Method:ELECTRON MICROSCOPY (3.66 Å)
Cite:Structural and functional properties of a plant NRAMP-related aluminum transporter.
Elife, 12, 2023
4K1S
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BU of 4k1s by Molmil
Gly-Ser-SplB protease from Staphylococcus aureus at 1.96 A resolution
Descriptor: Serine protease SplB
Authors:Zdzalik, M, Pustelny, K, Stec-Niemczyk, J, Cichon, P, Czarna, A, Popowicz, G, Drag, M, Wladyka, B, Potempa, J, Dubin, A, Dubin, G.
Deposit date:2013-04-05
Release date:2014-04-16
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Staphylococcal SplB Serine Protease Utilizes a Novel Molecular Mechanism of Activation.
J.Biol.Chem., 289, 2014
1ZJ3
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BU of 1zj3 by Molmil
Crystal Structure of Human Galactosyltransferase (GTB) Complexed with H type II Trisaccharide
Descriptor: ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase), ...
Authors:Letts, J.A, Rose, N.L, Fang, Y.R, Barry, C.H, Borisova, S.N, Seto, N.O, Palcic, M.M, Evans, S.V.
Deposit date:2005-04-28
Release date:2005-12-13
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:Differential Recognition of the Type I and II H Antigen Acceptors by the Human ABO(H) Blood Group A and B Glycosyltransferases.
J.Biol.Chem., 281, 2006
1ZIZ
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BU of 1ziz by Molmil
Crystal Structure of Human Galactosyltransferase (GTB) Complexed with Galactose
Descriptor: ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase), ...
Authors:Letts, J.A, Rose, N.L, Fang, Y.R, Barry, C.H, Borisova, S.N, Seto, N.O, Palcic, M.M, Evans, S.V.
Deposit date:2005-04-27
Release date:2005-12-13
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.49 Å)
Cite:Differential Recognition of the Type I and II H Antigen Acceptors by the Human ABO(H) Blood Group A and B Glycosyltransferases.
J.Biol.Chem., 281, 2006
1ZI3
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BU of 1zi3 by Molmil
Crystal Structure of Human N-acetylgalactosaminyltransferase (GTA) Complexed with N-acetyllactosamine
Descriptor: CHLORIDE ION, Histo-blood group ABO system transferase (NAGAT) Includes: Glycoprotein-fucosylgalactoside alpha-N- acetylgalactosaminyltransferase, MERCURY (II) ION, ...
Authors:Letts, J.A, Rose, N.L, Fang, Y.R, Barry, C.H, Borisova, S.N, Seto, N.O, Palcic, M.M, Evans, S.V.
Deposit date:2005-04-26
Release date:2005-12-13
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:Differential Recognition of the Type I and II H Antigen Acceptors by the Human ABO(H) Blood Group A and B Glycosyltransferases.
J.Biol.Chem., 281, 2006
1ZJ0
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BU of 1zj0 by Molmil
Crystal Structure of Human Galactosyltransferase (GTB) Complexed with Lactose
Descriptor: ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase), ...
Authors:Letts, J.A, Rose, N.L, Fang, Y.R, Barry, C.H, Borisova, S.N, Seto, N.O, Palcic, M.M, Evans, S.V.
Deposit date:2005-04-27
Release date:2005-12-13
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:Differential Recognition of the Type I and II H Antigen Acceptors by the Human ABO(H) Blood Group A and B Glycosyltransferases.
J.Biol.Chem., 281, 2006
8PFB
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BU of 8pfb by Molmil
Structure of a heteropolymeric type 4 pilus from a monoderm bacterium
Descriptor: Type IV pilin PilE1
Authors:Anger, R, Pieulle, L, Shahin, M, Valette, O, Le Guenno, H, Kosta, A, Pelicic, V, Fronzes, R.
Deposit date:2023-06-15
Release date:2023-11-22
Method:ELECTRON MICROSCOPY (3.67 Å)
Cite:Structure of a heteropolymeric type 4 pilus from a monoderm bacterium.
Nat Commun, 14, 2023
3N4W
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BU of 3n4w by Molmil
Crystal structure of an abridged SER to ALA mutant of the mature ectodomain of the human receptor-type protein-tyrosine phosphatase ICA512/IA-2 at pH 7.5
Descriptor: CALCIUM ION, Receptor-type tyrosine-protein phosphatase-like N
Authors:Primo, M.E, Jakoncic, J, Poskus, E, Ermacora, M.R.
Deposit date:2010-05-23
Release date:2010-12-01
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Structure of the mature ectodomain of the human receptor-type protein-tyrosine phosphatase IA-2.
J.Biol.Chem., 283, 2008
6BSB
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BU of 6bsb by Molmil
Crystal structure of the Mucin-1 SEA domain, L1105M mutant, Selenium-derivative
Descriptor: Mucin-1
Authors:Noguera, M.E, Jakoncic, J, Ermacora, M.R.
Deposit date:2017-12-01
Release date:2018-12-05
Last modified:2020-06-17
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:High-resolution structure of intramolecularly proteolyzed human mucin-1 SEA domain.
Biochim Biophys Acta Proteins Proteom, 1868, 2020
4ILS
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BU of 4ils by Molmil
Crystal structure of engineered protein. northeast structural genomics Consortium target or117
Descriptor: Engineered protein
Authors:Seetharaman, J, Lew, S, Nivon, L, Baker, D, Bjelic, S, Ciccosanti, C, Sahdev, S, Xiao, R, Everett, J.K, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG)
Deposit date:2012-12-31
Release date:2013-03-20
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of engineered protein. northeast structural genomics Consortium target or117
To be Published
4KC4
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BU of 4kc4 by Molmil
Structure of the blood group glycosyltransferase AAglyB in complex with a pyridine inhibitor as a neutral pyrophosphate surrogate
Descriptor: 5'-deoxy-5'-[({6-[(alpha-D-galactopyranosyloxy)methyl]pyridin-2-yl}carbonyl)amino]uridine, Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase, MANGANESE (II) ION, ...
Authors:Cuesta-Seijo, J.A, Wang, S, Lafont, D, Vidal, S, Palcic, M.M.
Deposit date:2013-04-24
Release date:2013-09-11
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Design of glycosyltransferase inhibitors: pyridine as a pyrophosphate surrogate.
Chemistry, 19, 2013
2A8W
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BU of 2a8w by Molmil
Crystal Structure of Human N-acetylgalactosaminyltransferase (GTA) Complexed with Beta-Methyllactoside
Descriptor: CHLORIDE ION, Histo-blood group ABO system transferase (NAGAT) [Includes: Glycoprotein-fucosylgalactoside alpha-N- acetylgalactosaminyltransferase (EC 2.4.1.40) (Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase) (Histo-blood group A transferase) (A transferase); Glycoprotein-fucosylgalactoside alpha- galactosyltransferase (EC 2.4.1.37) (Fucosylglycoprotein 3-alpha- galactosyltransferase) (Histo-blood group B transferase) (B transferase)] [Contains: Fucosylglycoprotein alpha-N- acetylgalactosaminyltransferase, soluble form], ...
Authors:Letts, J.A, Rose, N.L, Fang, Y.R, Barry, C.H, Borisova, S.N, Seto, N.O, Palcic, M.M, Evans, S.V.
Deposit date:2005-07-09
Release date:2005-12-13
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.59 Å)
Cite:Differential Recognition of the Type I and II H Antigen Acceptors by the Human ABO(H) Blood Group A and B Glycosyltransferases.
J.Biol.Chem., 281, 2006
1ZZF
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BU of 1zzf by Molmil
The DNA-bound solution structure of HPV-16 E2 DNA-binding domain
Descriptor: Regulatory protein E2
Authors:Eliseo, T, Nadra, A.D, De Prat-Gay, G, Paci, M, Cicero, O.D.
Deposit date:2005-06-14
Release date:2006-03-14
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:The DNA-bound solution structure of HPV-16 E2 DNA-binding domain
to be published
2G7C
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BU of 2g7c by Molmil
Clostridium difficile Toxin A Fragment Bound to aGal(1,3)bGal(1,4)bGlcNAc
Descriptor: GLYCEROL, Toxin A, alpha-D-galactopyranose-(1-3)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Greco, A, Ho, J.G.S, Lin, S.J, Palcic, M.M, Rupnik, M, Ng, K.K.S.
Deposit date:2006-02-28
Release date:2006-04-18
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Carbohydrate recognition by Clostridium difficile toxin A.
Nat.Struct.Mol.Biol., 13, 2006
4KC1
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BU of 4kc1 by Molmil
Structure of the blood group glycosyltransferase AAglyB in complex with a pyridine inhibitor as a neutral pyrophosphate surrogate
Descriptor: 6-(1-beta-D-Glucopyranosyloxymethyl)-N-(5'-deoxyluridine-5'-yl)picolinamide, Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase, MANGANESE (II) ION, ...
Authors:Cuesta-Seijo, J.A, Wang, S, Lafont, D, Vidal, S, Palcic, M.M.
Deposit date:2013-04-24
Release date:2013-09-11
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Design of glycosyltransferase inhibitors: pyridine as a pyrophosphate surrogate.
Chemistry, 19, 2013
2FBO
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BU of 2fbo by Molmil
Crystal Structure of the Two Tandem V-type Regions of VCBP3 (v-region-containing chitin binding protein) to 1.85 A
Descriptor: variable region-containing chitin-binding protein 3
Authors:Hernandez Prada, J.A, Haire, R.N, Jakoncic, J, Cannon, J.P, Litman, G.W, Ostrov, D.A.
Deposit date:2005-12-09
Release date:2006-10-17
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Ancient evolutionary origin of diversified variable regions demonstrated by crystal structures of an immune-type receptor in amphioxus
Nat.Immunol., 7, 2006
4KC2
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BU of 4kc2 by Molmil
Structure of the blood group glycosyltransferase AAglyB in complex with a pyridine inhibitor as a neutral pyrophosphate surrogate
Descriptor: 6-(1-beta-D-Galactopyranosyloxymethyl)-N-(5'-deoxyluridine-5'-yl)picolinamide, Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase soluble form, MANGANESE (II) ION, ...
Authors:Cuesta-Seijo, J.A, Wang, S, Lafont, D, Vidal, S, Palcic, M.M.
Deposit date:2013-04-24
Release date:2013-09-11
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Design of glycosyltransferase inhibitors: pyridine as a pyrophosphate surrogate.
Chemistry, 19, 2013
2AZR
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BU of 2azr by Molmil
Crystal structure of PTP1B with Bicyclic Thiophene inhibitor
Descriptor: 3-(CARBOXYMETHOXY)THIENO[2,3-B]PYRIDINE-2-CARBOXYLIC ACID, Tyrosine-protein phosphatase, non-receptor type 1
Authors:Moretto, A.F, Kirincich, S.J, Xu, W.X, Smith, M.J, Wan, Z.K, Wilson, D.P, Follows, B.C, Binnun, E, Joseph-McCarthy, D, Foreman, K, Erbe, D.V, Zhang, Y.L, Tam, S.K, Tam, S.Y, Lee, J.
Deposit date:2005-09-12
Release date:2005-12-06
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Bicyclic and tricyclic thiophenes as protein tyrosine phosphatase 1B inhibitors.
Bioorg.Med.Chem., 14, 2006

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